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3 accessions found for Halorubrum lacusprofundi ATCC 49239  

Data for CP001365  

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hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
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HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: CP001365.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
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Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
CP001365_0465 CDS_487530-486394 66.1 1.5e-18 1
CP001365_2649 CDS_2672899-2674449 62.3 1.7e-17 1
CP001365_0995 CDS_1001901-999136 60.2 6.9e-17 1
CP001365_1782 CDS_1824342-1825463 59.5 1.1e-16 1
CP001365_1335 CDS_1365989-1363362 57.0 5.4e-16 1
CP001365_1501 CDS_1532290-1530773 54.9 2.2e-15 1
CP001365_1217 CDS_1241385-1242515 52.3 1.1e-14 1
CP001365_1880 CDS_1912957-1911368 52.1 1.4e-14 1
CP001365_0912 CDS_919551-917584 51.8 1.6e-14 1
CP001365_2097 CDS_2118804-2117125 47.9 2.1e-13 1
CP001365_0714 CDS_732041-730092 47.5 2.8e-13 1
CP001365_2562 CDS_2575812-2574736 39.9 3.9e-11 1
CP001365_1773 CDS_1814739-1816505 32.5 4.8e-09 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CP001365_0465 1/1 140 201 .. 1 87 [] 66.1 1.5e-18
CP001365_2649 1/1 279 340 .. 1 87 [] 62.3 1.7e-17
CP001365_0995 1/1 703 764 .. 1 87 [] 60.2 6.9e-17
CP001365_1782 1/1 110 174 .. 1 87 [] 59.5 1.1e-16
CP001365_1335 1/1 659 720 .. 1 87 [] 57.0 5.4e-16
CP001365_1501 1/1 282 343 .. 1 87 [] 54.9 2.2e-15
CP001365_1217 1/1 174 235 .. 1 87 [] 52.3 1.1e-14
CP001365_1880 1/1 300 366 .. 1 87 [] 52.1 1.4e-14
CP001365_0912 1/1 452 513 .. 1 87 [] 51.8 1.6e-14
CP001365_2097 1/1 351 414 .. 1 87 [] 47.9 2.1e-13
CP001365_0714 1/1 432 493 .. 1 87 [] 47.5 2.8e-13
CP001365_2562 1/1 150 211 .. 1 87 [] 39.9 3.9e-11
CP001365_1773 1/1 350 414 .. 1 87 [] 32.5 4.8e-09

Alignments of top-scoring domains:
CP001365_0465: domain 1 of 1, from 140 to 201: score 66.1, E = 1.5e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++ef++ +sH+LR+PL++ +g ++l++ee+d
CP001365_0 140 RLEEFASIVSHDLRNPLNVAQGRLDLAREEYD--------------- 171

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e le++ ++ er+ +Li+dlL+l+r ++g
CP001365_0 172 ----------SEHLEVVANAHERMAALIDDLLTLARDGEG 201

CP001365_2649: domain 1 of 1, from 279 to 340: score 62.3, E = 1.7e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f++ +sH+LR+PL++Irg e+++ + + e
CP001365_2 279 RLDRFASIVSHDLRNPLSVIRGSMEMAEL----------NGDTEP-- 313

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
le+ +r+++r+++L+++lL+l+r ++g
CP001365_2 314 -------------LERGERAVDRIDQLVSELLTLARQGSG 340

CP001365_0995: domain 1 of 1, from 703 to 764: score 60.2, E = 6.9e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ ef++ +sH+LR+PL++ +g ++l+++ e+++e
CP001365_0 703 RLAEFASVVSHDLRNPLNVAQGRVQLARD----------ECDSEN-- 737

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
l+ + r+ er++ Li dlL+l+r ++
CP001365_0 738 -------------LDAAARAHERMDTLIADLLTLAREGER 764

CP001365_1782: domain 1 of 1, from 110 to 174: score 59.5, E = 1.1e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++ef++ +sH+LR+PL++ g++el++e + e++
CP001365_1 110 RLEEFASVVSHDLRNPLSVAVGNIELARE-----------FDGEEV- 144

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e l++++++++ +++Li+d+L l+r +
CP001365_1 145 ----------DERLDRAHDALDWMDDLISDVLALAREGRS 174

CP001365_1335: domain 1 of 1, from 659 to 720: score 57.0, E = 5.4e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++ef++ +sH+LR+PL++++gy+ l++e
CP001365_1 659 RLDEFASIVSHDLRNPLNVLSGYLRLARE-------------TGN-- 690

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ y+e+ + +++ ++rLi d+L+l+r +
CP001365_1 691 ----------ESYFERCDTALDEMERLIADVLTLARQGDA 720

CP001365_1501: domain 1 of 1, from 282 to 343: score 54.9, E = 2.2e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f a +sH+LR+PL++++gy++l ++ e s +
CP001365_1 282 QLEQFSAVVSHDLRNPLNVLSGYLDLVEN----------EISLST-- 316

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e ++r++ r+++Li++lL l++ +
CP001365_1 317 -------------YEPMDRAVTRMEALIDNLLMLAKRGDT 343

CP001365_1217: domain 1 of 1, from 174 to 235: score 52.3, E = 1.1e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f++ +sH+LR PL++ +g ++l + ++++++
CP001365_1 174 RLDQFASVVSHDLRSPLNVAQGRVDLERS----------TRDSDH-- 208

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
l ++ r+++r+++Li d+L+ +r +++
CP001365_1 209 -------------LGIAARSLDRMEDLIADVLTVARQGQE 235

CP001365_1880: domain 1 of 1, from 300 to 366: score 52.1, E = 1.4e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++ef++ +sH+LR PL++ g+++l++e++ e+ e+ +
CP001365_1 300 RLEEFASLVSHDLRSPLNVATGNLDLIRERF-------REQHEDLAE 339

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++t+ r+++r+++L++d+L+l+r ++
CP001365_1 340 -------------IDTVARSLDRMEALVEDMLTLARQGSA 366

CP001365_0912: domain 1 of 1, from 452 to 513: score 51.8, E = 1.6e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f++++sH+LR+PL++ +g++el +e +ee r
CP001365_0 452 RLEQFASMVSHDLRNPLSVASGNLELYRE-----------TGEESR- 486

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
leti+ ++ r+++Li dl l+r + +
CP001365_0 487 -------------LETIDTALTRIQELITDLTSLARYGIP 513

CP001365_2097: domain 1 of 1, from 351 to 414: score 47.9, E = 2.1e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+ +sH+LR+PL+a +++el++ ++++ e++
CP001365_2 351 RLEDFAGVVSHDLRNPLAAATAAVELARH---------GDRNNEDA- 387

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
l+++ ++ er+++Li+ lL l+ ++
CP001365_2 388 -------------LDRAANAHERMDDLIEGLLSLATAGKS 414

CP001365_0714: domain 1 of 1, from 432 to 493: score 47.5, E = 2.8e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++ef++ +sH+LR+PL++ gy+ l+ e + +
CP001365_0 432 RLDEFASIVSHDLRNPLSVAEGYVTLANE----------TGEIAH-- 466

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
le+ l++++r+++L+ dlL l+r ++
CP001365_0 467 -------------LEKTLEALDRMDELVGDLLSLARQGEA 493

CP001365_2562: domain 1 of 1, from 150 to 211: score 39.9, E = 3.9e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++++ lsH+L++PL++ rgy++++++ + + +
CP001365_2 150 RLERLSGFLSHDLKNPLAVARGYLDVARD----------TGDLDR-- 184

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
l+ ++++++r++ Li++ L ++r a
CP001365_2 185 -------------LDPADDALDRIETLIDEALVMAREPAV 211

CP001365_1773: domain 1 of 1, from 350 to 414: score 32.5, E = 4.8e-09
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++ + + ++H++R+ +++I g +e+L++ + + e
CP001365_1 350 QLEALNRVVRHDIRNDMAVIHGWSETLRD----------HVDKEG-- 384

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l+++lr + + +L + +d+ +g
CP001365_1 385 ----------QDALDRVLRKSTHVIELTETARDFVDSLTG 414


Histogram of all scores:
score obs exp (one = represents 9 sequences)
----- --- ---
-15 1 0|=
-14 11 0|==
-13 38 2|*====
-12 151 61|======*==========
-11 281 321|================================ *
-10 499 596|======================================================== *
-9 513 615|========================================================= *
-8 426 460|================================================ *
-7 330 290|================================*====
-6 191 167|==================*===
-5 118 91|==========*===
-4 64 49|=====*==
-3 23 25|==*
-2 20 13|=*=
-1 13 7|*=
0 3 3|*
1 7 1|*
2 3 1|*
3 0 0|
> 4 19 -|===


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 197.6680
P(chi-square) = 2.266e-36

Total sequences searched: 2711

Whole sequence top hits:
tophits_s report:
Total hits: 13
Satisfying E cutoff: 13
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 13
Satisfying E cutoff: 13
Total memory: 26K


Acknowledgements:

This research is funded by:

Developed by: