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Classification of phyla is from NCBI page
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264 projects found  

2 accessions found for Escherichia coli O157:H7 str. TW14359  

Data for CP001368  

Available Atlases
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hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: CP001368.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
CP001368_3592 CDS_3696579-3699335 100.1 6.4e-28 1
CP001368_0442 CDS_485048-486343 91.0 2.5e-25 1
CP001368_3196 CDS_3271498-3275091 81.6 1.1e-22 1
CP001368_1114 CDS_1239850-1237106 80.7 2e-22 1
CP001368_2982 CDS_3049096-3046247 80.6 2.2e-22 1
CP001368_4023 CDS_4153186-4150850 78.9 6.8e-22 1
CP001368_3369 CDS_3470452-3469025 75.4 6.6e-21 1
CP001368_2727 CDS_2802124-2803527 69.8 2.6e-19 1
CP001368_4775 CDS_4964108-4962735 66.6 2e-18 1
CP001368_5259 CDS_5523180-5524604 62.4 3.1e-17 1
CP001368_4865 CDS_5069924-5071300 61.5 5.7e-17 1
CP001368_0599 CDS_682298-680850 61.0 7.9e-17 1
CP001368_3842 CDS_3969036-3970385 60.7 9.8e-17 1
CP001368_4726 CDS_4911425-4910376 59.7 1.9e-16 1
CP001368_0709 CDS_807709-805025 59.6 1.9e-16 1
CP001368_4183 CDS_4307183-4305831 55.0 3.9e-15 1
CP001368_2484 CDS_2569283-2567925 52.3 2.2e-14 1
CP001368_4998 CDS_5218982-5217891 45.0 2.7e-12 1
CP001368_2090 CDS_2187959-2189260 42.4 1.5e-11 1
CP001368_4977 CDS_5197714-5199984 36.1 8.9e-10 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CP001368_3592 1/1 292 357 .. 1 87 [] 100.1 6.4e-28
CP001368_0442 1/1 203 269 .. 1 87 [] 91.0 2.5e-25
CP001368_3196 1/1 711 777 .. 1 87 [] 81.6 1.1e-22
CP001368_1114 1/1 443 508 .. 1 87 [] 80.7 2e-22
CP001368_2982 1/1 469 534 .. 1 87 [] 80.6 2.2e-22
CP001368_4023 1/1 282 347 .. 1 87 [] 78.9 6.8e-22
CP001368_3369 1/1 249 317 .. 1 87 [] 75.4 6.6e-21
CP001368_2727 1/1 240 304 .. 1 87 [] 69.8 2.6e-19
CP001368_4775 1/1 238 300 .. 1 87 [] 66.6 2e-18
CP001368_5259 1/1 255 320 .. 1 87 [] 62.4 3.1e-17
CP001368_4865 1/1 237 303 .. 1 87 [] 61.5 5.7e-17
CP001368_0599 1/1 261 327 .. 1 87 [] 61.0 7.9e-17
CP001368_3842 1/1 236 302 .. 1 87 [] 60.7 9.8e-17
CP001368_4726 1/1 129 186 .. 1 79 [. 59.7 1.9e-16
CP001368_0709 1/1 663 730 .. 1 87 [] 59.6 1.9e-16
CP001368_4183 1/1 233 293 .. 1 87 [] 55.0 3.9e-15
CP001368_2484 1/1 235 301 .. 1 87 [] 52.3 2.2e-14
CP001368_4998 1/1 142 202 .. 1 87 [] 45.0 2.7e-12
CP001368_2090 1/1 211 271 .. 1 87 [] 42.4 1.5e-11
CP001368_4977 1/1 400 462 .. 1 87 [] 36.1 8.9e-10

Alignments of top-scoring domains:
CP001368_3592: domain 1 of 1, from 292 to 357: score 100.1, E = 6.4e-28
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
kseflan+sHELRTPL++++g++ l l+ tel++ q
CP001368_3 292 IKSEFLANMSHELRTPLNGVIGFTRLTLK---------TELTPTQ-- 327

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+ l+ti+r+a+ ll++ind+Ld+s++eag
CP001368_3 328 ----------RDHLNTIERSANNLLAIINDVLDFSKLEAG 357

CP001368_0442: domain 1 of 1, from 203 to 269: score 91.0, E = 2.5e-25
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++ f+an+sHELRTPLt+++gy+e++ e ++l r
CP001368_0 203 ARRNFFANVSHELRTPLTVLQGYLEMMDE---------QPLEGAVR- 239

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l+t++++++r++ L+ +lL+ls+iea
CP001368_0 240 ----------EKALHTMREQTQRMEGLVKQLLTLSKIEAA 269

CP001368_3196: domain 1 of 1, from 711 to 777: score 81.6, E = 1.1e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks+fla++sHE+RTP+++I+g++elL + ls eqr
CP001368_3 711 AKSQFLATMSHEIRTPISSIMGFLELLSG---------SGLSKEQR- 747

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e+++ ++ +++ll Li ++Ld +ie+g
CP001368_3 748 ----------VEAISLAYATGQSLLGLIGEILDVDKIESG 777

CP001368_1114: domain 1 of 1, from 443 to 508: score 80.7, E = 2e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks fla++sHE+RTPL +I+g+a+lL + ++ q
CP001368_1 443 AKSAFLAAMSHEIRTPLYGILGTAQLLAD---------NPALNAQ-- 478

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+ l+ i +++e+ll ++nd+Ld+s ieag
CP001368_1 479 ----------RDDLRAITDSGESLLTILNDILDYSAIEAG 508

CP001368_2982: domain 1 of 1, from 469 to 534: score 80.6, E = 2.2e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ks fla++sHELRTPL +I+g+++lL++ el+
CP001368_2 469 SKSMFLATVSHELRTPLYGIIGNLDLLQT---------KELPKGV-- 504

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ + +++ ll++i+d+Ld+s+ie++
CP001368_2 505 ----------DRLVTAMNNSSSLLLKIISDILDFSKIESE 534

CP001368_4023: domain 1 of 1, from 282 to 347: score 78.9, E = 6.8e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k+ f++++sHELRTPL++I g++ +Ll+ tel++eq
CP001368_4 282 DKTTFISTISHELRTPLNGIVGLSRILLD---------TELTAEQ-- 317

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++yl+ti+ +a l ++ nd+ d+ ++e
CP001368_4 318 ----------EKYLKTIHVSAVTLGNIFNDIIDMDKMERR 347

CP001368_3369: domain 1 of 1, from 249 to 317: score 75.4, E = 6.6e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +fl++lsHEL+TPL+++r +elL +++ ++l++eq
CP001368_3 249 QRHQFLRHLSHELKTPLASMREGTELLADQV------VGPLTPEQ-- 287

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e +++++++++ l++Li++lLd+ r +a
CP001368_3 288 ----------KEVVSILDSSSRNLQKLIEQLLDYNRKQAD 317

CP001368_2727: domain 1 of 1, from 240 to 304: score 69.8, E = 2.6e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+a++sHELRTPL+++rg +e++++++ + ++e+
CP001368_2 240 MRRDFMADISHELRTPLAVLRGELEAIQDGV-------RKFTPET-- 277

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +++ e+ l +L++dl +ls ++g
CP001368_2 278 -------------VASLQAEVGTLTKLVDDLHQLSMSDEG 304

CP001368_4775: domain 1 of 1, from 238 to 300: score 66.6, E = 2e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++++l+++sHELRTPLt +++ + lL++ +++
CP001368_4 238 SQQRLLSDISHELRTPLTRLQLGTALLRR---------RSGESKE-- 273

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
le+i+ ea+rl+++indlL +sr ++
CP001368_4 274 -------------LERIETEAQRLDSMINDLLVMSRNQQK 300

CP001368_5259: domain 1 of 1, from 255 to 320: score 62.4, E = 3.1e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ + +l HEL+ PL+aIrg+ae+L+e ++ +e
CP001368_5 255 YIEQYVYALTHELKSPLAAIRGAAEILRE---------GPPPEVV-- 290

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++++ il + r+++L++ lL +r+e+
CP001368_5 291 ----------ARFTDNILTQNARMQALVETLLRQARLENR 320

CP001368_4865: domain 1 of 1, from 237 to 303: score 61.5, E = 5.7e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++ ++a+++HE+R+PL++I+g+a+ e +++++ e
CP001368_4 237 ALGHLAAGVAHEIRNPLSSIKGLAKYFAE--------RAPAGGEA-- 273

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ +++ +ea+rl+r +++lL+l + +
CP001368_4 274 ----------HQLAQVMAKEADRLNRVVSELLELVKPTHL 303

CP001368_0599: domain 1 of 1, from 261 to 327: score 61.0, E = 7.9e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++s f a+++HE+RTP+t +++ +e++l + +s +++
CP001368_0 261 RQSNFSADIAHEIRTPITNLITQTEIALS---------QSRSQKEL- 297

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ l + l+e+ r+ ++++d+L l++++++
CP001368_0 298 ----------EDVLYSNLEELTRMAKMVSDMLFLAQADNN 327

CP001368_3842: domain 1 of 1, from 236 to 302: score 60.7, E = 9.8e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++f+++++HELR PLta++ +e+++ ++ +++ r
CP001368_3 236 RERRFTSDAAHELRSPLTALKVQTEVAQL---------SDDDPQAR- 272

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l +++ ++r rL+++lL+lsr+++
CP001368_3 273 ----------KKALLQLHSGIDRATRLVDQLLTLSRLDSL 302

CP001368_4726: domain 1 of 1, from 129 to 186: score 59.7, E = 1.9e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a ++++++l+HE+++PL ++rg+a+lL + +l+++ +
CP001368_4 129 AARDLVRGLAHEIKNPLGGLRGAAQLLSK----------ALPDPSL- 164

peLRledpeyreyletilreaerllrLindlL<-*
ey+++i+++a+rl++L+++lL
CP001368_4 165 ----------LEYTKVIIEQADRLRNLVDRLL 186

CP001368_0709: domain 1 of 1, from 663 to 730: score 59.6, E = 1.9e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +la+lsH+LRTPLt++ g ae+L +l + ++++
CP001368_0 663 IRNALLAALSHDLRTPLTVLFGQAEILTLDL-------ASEGSPH-- 700

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ + i++ + rL+n+lLd++ri++g
CP001368_0 701 ----------ARQASEIRQHVLNTTRLVNNLLDMARIQSG 730

CP001368_4183: domain 1 of 1, from 233 to 293: score 55.0, E = 3.9e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ ++a++sH+LRTPLt Ir+++e++ e ++
CP001368_4 233 DRTLLMAGVSHDLRTPLTRIRLATEMMSE---------QD------- 263

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ e+i +++e ++++i+++ d+ r +++
CP001368_4 264 ----------GYLAESINKDIEECNAIIEQFIDYLRTGQE 293

CP001368_2484: domain 1 of 1, from 235 to 301: score 52.3, E = 2.2e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++s+f+ +l+HELRTP++a++g ++ l +++s +
CP001368_2 235 RLSQFADDLAHELRTPINALLGQNQVTLS---------QTRSIAE-- 270

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
y++ + ++e+e ++rL +++L l+r++ +
CP001368_2 271 ---------YQKTIAGNIEELENISRLTENILFLARADKN 301

CP001368_4998: domain 1 of 1, from 142 to 202: score 45.0, E = 2.7e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ f+a+++HELRTPL+++r+++elL + t+
CP001368_4 142 NERLFTADVAHELRTPLAGVRLHLELLAK---------TH------- 172

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + + ++++ + +++lL+l+r+++
CP001368_4 173 ----------HIDVAPLVARLDQMMESVSQLLQLARAGQS 202

CP001368_2090: domain 1 of 1, from 211 to 271: score 42.4, E = 1.5e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+k +++ +++HELRTPL +r +e+ + ls+ +
CP001368_2 211 SKKQLIDGIAHELRTPLVRLRYRLEMSDN-----------LSAAE-- 244

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + r++ +l++Li++lL+++r++ +
CP001368_2 245 -------------SQALNRDISQLEALIEELLTYARLDRP 271

CP001368_4977: domain 1 of 1, from 400 to 462: score 36.1, E = 8.9e-10
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a ++++ +l+H++++ L++I+g +el + +++
CP001368_4 400 AVGQLTGGLAHDFNNLLAVIIGSLELVNP---------DSPDAPR-- 435

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++++l++aer L ++lL +sr ++
CP001368_4 436 -------------IQRALQAAERGALLTQRLLAFSRKQSL 462


Histogram of all scores:
score obs exp (one = represents 17 sequences)
----- --- ---
-16 2 0|=
-15 11 0|=
-14 32 0|==
-13 114 3|*======
-12 316 120|=======*===========
-11 533 623|================================ *
-10 886 1157|===================================================== *
-9 999 1195|==========================================================*
-8 858 894|=================================================== *
-7 611 563|=================================*==
-6 377 324|===================*===
-5 216 178|==========*==
-4 121 95|=====*==
-3 61 50|==*=
-2 31 26|=*
-1 40 13|*==
0 15 7|*
1 7 3|*
2 7 1|*
3 3 1|*
4 0 0|
5 1 0|=
6 0 0|
> 7 22 -|==


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 517.6651
P(chi-square) = 0

Total sequences searched: 5263

Whole sequence top hits:
tophits_s report:
Total hits: 20
Satisfying E cutoff: 20
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 20
Satisfying E cutoff: 20
Total memory: 28K


Acknowledgements:

This research is funded by:

Developed by: