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Classification of phyla is from NCBI page
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264 projects found  

6 accessions found for Shigella flexneri 2002017  

Data for CP001383  

Available Atlases
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hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: CP001383.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
CP001383_2781 CDS_2913818-2916574 100.1 5.3e-28 1
CP001383_0367 CDS_365261-366556 91.0 2.1e-25 1
CP001383_2433 CDS_2525406-2528672 81.6 9.4e-23 1
CP001383_2303 CDS_2380236-2377387 80.6 1.9e-22 1
CP001383_3227 CDS_3385224-3382888 78.9 5.6e-22 1
CP001383_2591 CDS_2713728-2712238 73.0 2.6e-20 1
CP001383_3943 CDS_4159632-4158259 66.6 1.7e-18 1
CP001383_4371 CDS_4645902-4647326 62.4 2.6e-17 1
CP001383_4022 CDS_4260565-4261941 61.5 4.7e-17 1
CP001383_0499 CDS_506528-505086 61.0 6.5e-17 1
CP001383_3048 CDS_3201291-3202565 60.7 8.2e-17 1
CP001383_3892 CDS_4108851-4107802 59.7 1.6e-16 1
CP001383_3389 CDS_3541198-3539846 55.0 3.3e-15 1
CP001383_2045 CDS_2095868-2094510 51.1 4.1e-14 1
CP001383_4059 CDS_4315984-4317084 45.0 2.2e-12 1
CP001383_1678 CDS_1714531-1715832 42.4 1.2e-11 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CP001383_2781 1/1 292 357 .. 1 87 [] 100.1 5.3e-28
CP001383_0367 1/1 203 269 .. 1 87 [] 91.0 2.1e-25
CP001383_2433 1/1 602 668 .. 1 87 [] 81.6 9.4e-23
CP001383_2303 1/1 469 534 .. 1 87 [] 80.6 1.9e-22
CP001383_3227 1/1 282 347 .. 1 87 [] 78.9 5.6e-22
CP001383_2591 1/1 270 338 .. 1 87 [] 73.0 2.6e-20
CP001383_3943 1/1 238 300 .. 1 87 [] 66.6 1.7e-18
CP001383_4371 1/1 255 320 .. 1 87 [] 62.4 2.6e-17
CP001383_4022 1/1 237 303 .. 1 87 [] 61.5 4.7e-17
CP001383_0499 1/1 261 327 .. 1 87 [] 61.0 6.5e-17
CP001383_3048 1/1 236 302 .. 1 87 [] 60.7 8.2e-17
CP001383_3892 1/1 129 186 .. 1 79 [. 59.7 1.6e-16
CP001383_3389 1/1 233 293 .. 1 87 [] 55.0 3.3e-15
CP001383_2045 1/1 235 301 .. 1 87 [] 51.1 4.1e-14
CP001383_4059 1/1 145 205 .. 1 87 [] 45.0 2.2e-12
CP001383_1678 1/1 211 271 .. 1 87 [] 42.4 1.2e-11

Alignments of top-scoring domains:
CP001383_2781: domain 1 of 1, from 292 to 357: score 100.1, E = 5.3e-28
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
kseflan+sHELRTPL++++g++ l l+ tel++ q
CP001383_2 292 IKSEFLANMSHELRTPLNGVIGFTRLTLK---------TELTPTQ-- 327

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+ l+ti+r+a+ ll++ind+Ld+s++eag
CP001383_2 328 ----------RDHLNTIERSANNLLAIINDVLDFSKLEAG 357

CP001383_0367: domain 1 of 1, from 203 to 269: score 91.0, E = 2.1e-25
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++ f+an+sHELRTPLt+++gy+e++ e ++l r
CP001383_0 203 ARRNFFANVSHELRTPLTVLQGYLEMMDE---------QPLEGAVR- 239

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l+t++++++r++ L+ +lL+ls+iea
CP001383_0 240 ----------EKALHTMREQTQRMEGLVKQLLTLSKIEAA 269

CP001383_2433: domain 1 of 1, from 602 to 668: score 81.6, E = 9.4e-23
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks+fla++sHE+RTP+++I+g++elL + ls eqr
CP001383_2 602 AKSQFLATMSHEIRTPISSIMGFLELLSG---------SGLSKEQR- 638

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e+++ ++ +++ll Li ++Ld +ie+g
CP001383_2 639 ----------VEAISLAYATGQSLLGLIGEILDVDKIESG 668

CP001383_2303: domain 1 of 1, from 469 to 534: score 80.6, E = 1.9e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ks fla++sHELRTPL +I+g+++lL++ el+
CP001383_2 469 SKSMFLATVSHELRTPLYGIIGNLDLLQT---------KELPKGV-- 504

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ + +++ ll++i+d+Ld+s+ie++
CP001383_2 505 ----------DRLVTAMNNSSSLLLKIISDILDFSKIESE 534

CP001383_3227: domain 1 of 1, from 282 to 347: score 78.9, E = 5.6e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k+ f++++sHELRTPL++I g++ +Ll+ tel++eq
CP001383_3 282 DKTTFISTISHELRTPLNGIVGLSRILLD---------TELTAEQ-- 317

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++yl+ti+ +a l ++ nd+ d+ ++e
CP001383_3 318 ----------EKYLKTIHVSAVTLGNIFNDIIDMDKMERR 347

CP001383_2591: domain 1 of 1, from 270 to 338: score 73.0, E = 2.6e-20
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +fl++lsHEL+TPL+++r +elL +++ ++l++eq
CP001383_2 270 QRHQFLRHLSHELKTPLASMREGTELLADQV------VGPLTPEQ-- 308

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e ++++++++ l++Li++lLd+ r +a
CP001383_2 309 ----------KEVVSILDSSSCNLQKLIEQLLDYNRKQAD 338

CP001383_3943: domain 1 of 1, from 238 to 300: score 66.6, E = 1.7e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++++l+++sHELRTPLt +++ + lL++ +++
CP001383_3 238 SQQRLLSDISHELRTPLTRLQLGTALLRR---------RSGESKE-- 273

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
le+i+ ea+rl+++indlL +sr ++
CP001383_3 274 -------------LERIETEAQRLDSMINDLLVMSRNQQK 300

CP001383_4371: domain 1 of 1, from 255 to 320: score 62.4, E = 2.6e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ + +l HEL+ PL+aIrg+ae+L+e ++ +e
CP001383_4 255 YIEQYVYALTHELKSPLAAIRGAAEILRE---------GPPPEVV-- 290

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++++ il + r+++L++ lL +r+e+
CP001383_4 291 ----------ARFTDNILTQNARMQALVETLLRQARLENR 320

CP001383_4022: domain 1 of 1, from 237 to 303: score 61.5, E = 4.7e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++ ++a+++HE+R+PL++I+g+a+ e +++++ e
CP001383_4 237 ALGHLAAGVAHEIRNPLSSIKGLAKYFAE--------RAPAGGEA-- 273

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ +++ +ea+rl+r +++lL+l + +
CP001383_4 274 ----------HQLAQVMAKEADRLNRVVSELLELVKPTHL 303

CP001383_0499: domain 1 of 1, from 261 to 327: score 61.0, E = 6.5e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++s f a+++HE+RTP+t +++ +e++l + +s +++
CP001383_0 261 RQSNFSADIAHEIRTPITNLITQTEIALS---------QSRSQKEL- 297

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ l + l+e+ r+ ++++d+L l++++++
CP001383_0 298 ----------EDVLYSNLEELTRMAKMVSDMLFLAQADNN 327

CP001383_3048: domain 1 of 1, from 236 to 302: score 60.7, E = 8.2e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++f+++++HELR PLta++ +e+++ ++ +++ r
CP001383_3 236 RERRFTSDAAHELRSPLTALKVQTEVAQL---------SDDDPQAR- 272

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l +++ ++r rL+++lL+lsr+++
CP001383_3 273 ----------KKALLQLHSGIDRATRLVDQLLTLSRLDSL 302

CP001383_3892: domain 1 of 1, from 129 to 186: score 59.7, E = 1.6e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a ++++++l+HE+++PL ++rg+a+lL + +l+++ +
CP001383_3 129 AARDLVRGLAHEIKNPLGGLRGAAQLLSK----------ALPDPSL- 164

peLRledpeyreyletilreaerllrLindlL<-*
ey+++i+++a+rl++L+++lL
CP001383_3 165 ----------LEYTKVIIEQADRLRNLVDRLL 186

CP001383_3389: domain 1 of 1, from 233 to 293: score 55.0, E = 3.3e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ ++a++sH+LRTPLt Ir+++e++ e ++
CP001383_3 233 DRTLLMAGVSHDLRTPLTRIRLATEMMSE---------QD------- 263

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ e+i +++e ++++i+++ d+ r +++
CP001383_3 264 ----------GYLAESINKDIEECNAIIEQFIDYLRTGQE 293

CP001383_2045: domain 1 of 1, from 235 to 301: score 51.1, E = 4.1e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++s+f+ +l+HELRTP++a++g ++ l + +s +
CP001383_2 235 RLSQFADDLAHELRTPINALLGQNQVTLS---------QIRSIAE-- 270

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
y++ + ++e+e ++rL +++L l+r++ +
CP001383_2 271 ---------YQKTIAGNIEELENISRLTENILFLARADKN 301

CP001383_4059: domain 1 of 1, from 145 to 205: score 45.0, E = 2.2e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ f+a+++HELRTPL+++r+++elL + t+
CP001383_4 145 NERLFTADVAHELRTPLAGVRLHLELLAK---------TH------- 175

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + + ++++ + +++lL+l+r+++
CP001383_4 176 ----------HIDVAPLVARLDQMMESVSQLLQLARAGQS 205

CP001383_1678: domain 1 of 1, from 211 to 271: score 42.4, E = 1.2e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+k +++ +++HELRTPL +r +e+ + ls+ +
CP001383_1 211 SKKQLIDGIAHELRTPLVRLRYRLEMSDN-----------LSAAE-- 244

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + r++ +l++Li++lL+++r++ +
CP001383_1 245 -------------SQALNRDISQLEALIEELLTYARLDRP 271


Histogram of all scores:
score obs exp (one = represents 15 sequences)
----- --- ---
-15 3 0|=
-14 49 0|====
-13 81 3|*=====
-12 222 99|======*========
-11 500 518|==================================*
-10 729 962|================================================= *
-9 831 993|======================================================== *
-8 698 743|=============================================== *
-7 468 468|===============================*
-6 286 269|=================*==
-5 257 148|=========*========
-4 101 79|=====*=
-3 45 41|==*
-2 32 21|=*=
-1 24 11|*=
0 15 5|*
1 7 3|*
2 6 1|*
3 3 0|=
4 0 0|
> 5 18 -|==


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 354.7320
P(chi-square) = 0

Total sequences searched: 4375

Whole sequence top hits:
tophits_s report:
Total hits: 16
Satisfying E cutoff: 16
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 16
Satisfying E cutoff: 16
Total memory: 27K


Acknowledgements:

This research is funded by:

Developed by: