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Classification of phyla is from NCBI page
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264 projects found  

1 accessions found for Escherichia coli BW2952  

Data for CP001396  

Available Atlases
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hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: CP001396.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
CP001396_2518 CDS_2800227-2802983 100.1 4.9e-28 1
CP001396_0282 CDS_319872-321167 90.3 3.1e-25 1
CP001396_2133 CDS_2368201-2371794 81.6 8.8e-23 1
CP001396_0847 CDS_958369-955625 80.7 1.5e-22 1
CP001396_1987 CDS_2203703-2200854 80.6 1.7e-22 1
CP001396_2906 CDS_3238195-3235859 78.9 5.2e-22 1
CP001396_1988 CDS_2203870-2205696 76.4 2.7e-21 1
CP001396_2315 CDS_2574925-2573498 75.4 5.1e-21 1
CP001396_1862 CDS_2053383-2054786 69.8 2e-19 1
CP001396_3572 CDS_3992667-3991294 66.6 1.6e-18 1
CP001396_4080 CDS_4573203-4574627 62.4 2.4e-17 1
CP001396_3654 CDS_4089629-4091026 61.5 4.4e-17 1
CP001396_0441 CDS_496753-495311 61.0 6.1e-17 1
CP001396_2733 CDS_3055654-3057003 60.7 7.6e-17 1
CP001396_3530 CDS_3944031-3942982 59.7 1.5e-16 1
CP001396_0555 CDS_626397-623713 59.6 1.5e-16 1
CP001396_3089 CDS_3421047-3419695 55.0 3e-15 1
CP001396_1763 CDS_1928659-1927301 52.3 1.7e-14 1
CP001396_3814 CDS_4270030-4268939 45.0 2.1e-12 1
CP001396_1419 CDS_1572965-1574266 42.4 1.2e-11 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CP001396_2518 1/1 292 357 .. 1 87 [] 100.1 4.9e-28
CP001396_0282 1/1 203 269 .. 1 87 [] 90.3 3.1e-25
CP001396_2133 1/1 711 777 .. 1 87 [] 81.6 8.8e-23
CP001396_0847 1/1 443 508 .. 1 87 [] 80.7 1.5e-22
CP001396_1987 1/1 469 534 .. 1 87 [] 80.6 1.7e-22
CP001396_2906 1/1 282 347 .. 1 87 [] 78.9 5.2e-22
CP001396_1988 1/1 388 453 .. 1 87 [] 76.4 2.7e-21
CP001396_2315 1/1 249 317 .. 1 87 [] 75.4 5.1e-21
CP001396_1862 1/1 240 304 .. 1 87 [] 69.8 2e-19
CP001396_3572 1/1 238 300 .. 1 87 [] 66.6 1.6e-18
CP001396_4080 1/1 255 320 .. 1 87 [] 62.4 2.4e-17
CP001396_3654 1/1 244 310 .. 1 87 [] 61.5 4.4e-17
CP001396_0441 1/1 261 327 .. 1 87 [] 61.0 6.1e-17
CP001396_2733 1/1 236 302 .. 1 87 [] 60.7 7.6e-17
CP001396_3530 1/1 129 186 .. 1 79 [. 59.7 1.5e-16
CP001396_0555 1/1 663 730 .. 1 87 [] 59.6 1.5e-16
CP001396_3089 1/1 233 293 .. 1 87 [] 55.0 3e-15
CP001396_1763 1/1 235 301 .. 1 87 [] 52.3 1.7e-14
CP001396_3814 1/1 142 202 .. 1 87 [] 45.0 2.1e-12
CP001396_1419 1/1 211 271 .. 1 87 [] 42.4 1.2e-11

Alignments of top-scoring domains:
CP001396_2518: domain 1 of 1, from 292 to 357: score 100.1, E = 4.9e-28
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
kseflan+sHELRTPL++++g++ l l+ tel++ q
CP001396_2 292 IKSEFLANMSHELRTPLNGVIGFTRLTLK---------TELTPTQ-- 327

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+ l+ti+r+a+ ll++ind+Ld+s++eag
CP001396_2 328 ----------RDHLNTIERSANNLLAIINDVLDFSKLEAG 357

CP001396_0282: domain 1 of 1, from 203 to 269: score 90.3, E = 3.1e-25
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++ f+an+sHELRTPLt+++gy+e++ e ++l r
CP001396_0 203 ARRNFFANVSHELRTPLTVLQGYLEMMNE---------QPLEGAVR- 239

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l+t++++++r++ L+ +lL+ls+iea
CP001396_0 240 ----------EKALHTMREQTQRMEGLVKQLLTLSKIEAA 269

CP001396_2133: domain 1 of 1, from 711 to 777: score 81.6, E = 8.8e-23
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks+fla++sHE+RTP+++I+g++elL + ls eqr
CP001396_2 711 AKSQFLATMSHEIRTPISSIMGFLELLSG---------SGLSKEQR- 747

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e+++ ++ +++ll Li ++Ld +ie+g
CP001396_2 748 ----------VEAISLAYATGQSLLGLIGEILDVDKIESG 777

CP001396_0847: domain 1 of 1, from 443 to 508: score 80.7, E = 1.5e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks fla++sHE+RTPL +I+g+a+lL + ++ q
CP001396_0 443 AKSAFLAAMSHEIRTPLYGILGTAQLLAD---------NPALNAQ-- 478

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+ l+ i +++e+ll ++nd+Ld+s ieag
CP001396_0 479 ----------RDDLRAITDSGESLLTILNDILDYSAIEAG 508

CP001396_1987: domain 1 of 1, from 469 to 534: score 80.6, E = 1.7e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ks fla++sHELRTPL +I+g+++lL++ el+
CP001396_1 469 SKSMFLATVSHELRTPLYGIIGNLDLLQT---------KELPKGV-- 504

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ + +++ ll++i+d+Ld+s+ie++
CP001396_1 505 ----------DRLVTAMNNSSSLLLKIISDILDFSKIESE 534

CP001396_2906: domain 1 of 1, from 282 to 347: score 78.9, E = 5.2e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k+ f++++sHELRTPL++I g++ +Ll+ tel++eq
CP001396_2 282 DKTTFISTISHELRTPLNGIVGLSRILLD---------TELTAEQ-- 317

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++yl+ti+ +a l ++ nd+ d+ ++e
CP001396_2 318 ----------EKYLKTIHVSAVTLGNIFNDIIDMDKMERR 347

CP001396_1988: domain 1 of 1, from 388 to 453: score 76.4, E = 2.7e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++e++a+++HE R+PLtaIrgy+++L+ ++ ++ +
CP001396_1 388 TLGELMAGVAHEVRNPLTAIRGYVQILRQ---------QTSDPIH-- 423

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+eyl+++l+e++++++ i++lL++sr ++
CP001396_1 424 ----------QEYLSVVLKEIDSINKVIQQLLEFSRPRHS 453

CP001396_2315: domain 1 of 1, from 249 to 317: score 75.4, E = 5.1e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +fl++lsHEL+TPL+++r +elL +++ ++l++eq
CP001396_2 249 QRHQFLRHLSHELKTPLASMREGTELLADQV------VGPLTPEQ-- 287

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e +++++++++ l++Li++lLd+ r +a
CP001396_2 288 ----------KEVVSILDSSSRNLQKLIEQLLDYNRKQAD 317

CP001396_1862: domain 1 of 1, from 240 to 304: score 69.8, E = 2e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+a++sHELRTPL+++rg +e++++++ + ++e+
CP001396_1 240 MRRDFMADISHELRTPLAVLRGELEAIQDGV-------RKFTPET-- 277

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +++ e+ l +L++dl +ls ++g
CP001396_1 278 -------------VASLQAEVGTLTKLVDDLHQLSMSDEG 304

CP001396_3572: domain 1 of 1, from 238 to 300: score 66.6, E = 1.6e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++++l+++sHELRTPLt +++ + lL++ +++
CP001396_3 238 SQQRLLSDISHELRTPLTRLQLGTALLRR---------RSGESKE-- 273

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
le+i+ ea+rl+++indlL +sr ++
CP001396_3 274 -------------LERIETEAQRLDSMINDLLVMSRNQQK 300

CP001396_4080: domain 1 of 1, from 255 to 320: score 62.4, E = 2.4e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ + +l HEL+ PL+aIrg+ae+L+e ++ +e
CP001396_4 255 YIEQYVYALTHELKSPLAAIRGAAEILRE---------GPPPEVV-- 290

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++++ il + r+++L++ lL +r+e+
CP001396_4 291 ----------ARFTDNILTQNARMQALVETLLRQARLENR 320

CP001396_3654: domain 1 of 1, from 244 to 310: score 61.5, E = 4.4e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++ ++a+++HE+R+PL++I+g+a+ e +++++ e
CP001396_3 244 ALGHLAAGVAHEIRNPLSSIKGLAKYFAE--------RAPAGGEA-- 280

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ +++ +ea+rl+r +++lL+l + +
CP001396_3 281 ----------HQLAQVMAKEADRLNRVVSELLELVKPTHL 310

CP001396_0441: domain 1 of 1, from 261 to 327: score 61.0, E = 6.1e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++s f a+++HE+RTP+t +++ +e++l + +s +++
CP001396_0 261 RQSNFSADIAHEIRTPITNLITQTEIALS---------QSRSQKEL- 297

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ l + l+e+ r+ ++++d+L l++++++
CP001396_0 298 ----------EDVLYSNLEELTRMAKMVSDMLFLAQADNN 327

CP001396_2733: domain 1 of 1, from 236 to 302: score 60.7, E = 7.6e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++f+++++HELR PLta++ +e+++ ++ +++ r
CP001396_2 236 RERRFTSDAAHELRSPLTALKVQTEVAQL---------SDDDPQAR- 272

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l +++ ++r rL+++lL+lsr+++
CP001396_2 273 ----------KKALLQLHSGIDRATRLVDQLLTLSRLDSL 302

CP001396_3530: domain 1 of 1, from 129 to 186: score 59.7, E = 1.5e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a ++++++l+HE+++PL ++rg+a+lL + +l+++ +
CP001396_3 129 AARDLVRGLAHEIKNPLGGLRGAAQLLSK----------ALPDPSL- 164

peLRledpeyreyletilreaerllrLindlL<-*
ey+++i+++a+rl++L+++lL
CP001396_3 165 ----------LEYTKVIIEQADRLRNLVDRLL 186

CP001396_0555: domain 1 of 1, from 663 to 730: score 59.6, E = 1.5e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +la+lsH+LRTPLt++ g ae+L +l + ++++
CP001396_0 663 IRNALLAALSHDLRTPLTVLFGQAEILTLDL-------ASEGSPH-- 700

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ + i++ + rL+n+lLd++ri++g
CP001396_0 701 ----------ARQASEIRQHVLNTTRLVNNLLDMARIQSG 730

CP001396_3089: domain 1 of 1, from 233 to 293: score 55.0, E = 3e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ ++a++sH+LRTPLt Ir+++e++ e ++
CP001396_3 233 DRTLLMAGVSHDLRTPLTRIRLATEMMSE---------QD------- 263

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ e+i +++e ++++i+++ d+ r +++
CP001396_3 264 ----------GYLAESINKDIEECNAIIEQFIDYLRTGQE 293

CP001396_1763: domain 1 of 1, from 235 to 301: score 52.3, E = 1.7e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++s+f+ +l+HELRTP++a++g ++ l +++s +
CP001396_1 235 RLSQFADDLAHELRTPINALLGQNQVTLS---------QTRSIAE-- 270

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
y++ + ++e+e ++rL +++L l+r++ +
CP001396_1 271 ---------YQKTIAGNIEELENISRLTENILFLARADKN 301

CP001396_3814: domain 1 of 1, from 142 to 202: score 45.0, E = 2.1e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ f+a+++HELRTPL+++r+++elL + t+
CP001396_3 142 NERLFTADVAHELRTPLAGVRLHLELLAK---------TH------- 172

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + + ++++ + +++lL+l+r+++
CP001396_3 173 ----------HIDVAPLVARLDQMMESVSQLLQLARAGQS 202

CP001396_1419: domain 1 of 1, from 211 to 271: score 42.4, E = 1.2e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+k +++ +++HELRTPL +r +e+ + ls+ +
CP001396_1 211 SKKQLIDGIAHELRTPLVRLRYRLEMSDN-----------LSAAE-- 244

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + r++ +l++Li++lL+++r++ +
CP001396_1 245 -------------SQALNRDISQLEALIEELLTYARLDRP 271


Histogram of all scores:
score obs exp (one = represents 13 sequences)
----- --- ---
-16 1 0|=
-15 4 0|=
-14 13 0|=
-13 49 3|*===
-12 185 93|=======*=======
-11 414 484|================================ *
-10 700 898|====================================================== *
-9 752 927|==========================================================*
-8 689 694|=====================================================*
-7 497 437|=================================*=====
-6 328 251|===================*======
-5 187 138|==========*====
-4 90 73|=====*=
-3 55 39|==*==
-2 29 20|=*=
-1 34 10|*==
0 16 5|*=
1 6 2|*
2 11 1|*
3 2 0|=
4 0 0|
> 5 22 -|==


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 309.0043
P(chi-square) = 0

Total sequences searched: 4084

Whole sequence top hits:
tophits_s report:
Total hits: 20
Satisfying E cutoff: 20
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 20
Satisfying E cutoff: 20
Total memory: 28K


Acknowledgements:

This research is funded by:

Developed by: