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2 accessions found for Vibrio cholerae MJ-1236  

Data for CP001485  

Available Atlases
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hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: CP001485.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
CP001485_1950 CDS_2207459-2203464 97.7 1.6e-27 1
CP001485_0870 CDS_960067-957284 94.5 1.3e-26 1
CP001485_1511 CDS_1673806-1676016 90.9 1.4e-25 1
CP001485_2560 CDS_2890833-2889532 80.1 1.6e-22 1
CP001485_1861 CDS_2102618-2100900 79.8 2e-22 1
CP001485_0949 CDS_1066984-1069341 75.1 4.1e-21 1
CP001485_2744 CDS_3108296-3111685 74.7 5.5e-21 1
CP001485_1688 CDS_1880969-1884499 71.4 4.7e-20 1
CP001485_0589 CDS_673268-672204 60.6 5.5e-17 1
CP001485_1977 CDS_2240427-2241749 58.5 2.1e-16 1
CP001485_0291 CDS_328963-325520 56.5 7.6e-16 1
CP001485_1202 CDS_1336577-1337632 56.4 8.5e-16 1
CP001485_1404 CDS_1552038-1550245 52.4 1.1e-14 1
CP001485_0623 CDS_706280-707596 51.0 2.9e-14 2
CP001485_0644 CDS_734170-732776 50.2 4.7e-14 1
CP001485_1814 CDS_2028468-2030501 39.9 4e-11 1
CP001485_2146 CDS_2434934-2436889 29.3 3.9e-08 2

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CP001485_1950 1/1 606 671 .. 1 87 [] 97.7 1.6e-27
CP001485_0870 1/1 290 355 .. 1 87 [] 94.5 1.3e-26
CP001485_1511 1/1 356 421 .. 1 87 [] 90.9 1.4e-25
CP001485_2560 1/1 205 272 .. 1 87 [] 80.1 1.6e-22
CP001485_1861 1/1 211 275 .. 1 87 [] 79.8 2e-22
CP001485_0949 1/1 282 347 .. 1 87 [] 75.1 4.1e-21
CP001485_2744 1/1 459 527 .. 1 87 [] 74.7 5.5e-21
CP001485_1688 1/1 651 716 .. 1 87 [] 71.4 4.7e-20
CP001485_0589 1/1 131 196 .. 1 87 [] 60.6 5.5e-17
CP001485_1977 1/1 212 277 .. 1 87 [] 58.5 2.1e-16
CP001485_0291 1/1 788 853 .. 1 87 [] 56.5 7.6e-16
CP001485_1202 1/1 125 191 .. 1 87 [] 56.4 8.5e-16
CP001485_1404 1/1 373 441 .. 1 87 [] 52.4 1.1e-14
CP001485_0644 1/1 247 309 .. 1 87 [] 50.2 4.7e-14
CP001485_0623 2/2 226 286 .. 1 87 [] 49.3 8.6e-14
CP001485_1814 1/1 445 512 .. 1 87 [] 39.9 4e-11

Alignments of top-scoring domains:
CP001485_1950: domain 1 of 1, from 606 to 671: score 97.7, E = 1.6e-27
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
ak++flan+sHE+RTP++aI+g+a+l+l+ t+l+ q
CP001485_1 606 AKGDFLANMSHEIRTPMNAILGMAHLALN---------TPLDTTQ-- 641

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+y+ +i ++a+ ll +ind+Ld+s++eag
CP001485_1 642 ----------RKYVTRINESAKNLLGIINDILDFSKMEAG 671

CP001485_0870: domain 1 of 1, from 290 to 355: score 94.5, E = 1.3e-26
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
kseflan+sHELRTPL++++g++ +l+ t l+ q
CP001485_0 290 VKSEFLANMSHELRTPLNGVIGFTRQMLK---------TQLTNSQ-- 325

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++yl+ti+++a+ ll +ind+Ld+s++eag
CP001485_0 326 ----------ADYLQTIEKSANNLLTIINDILDFSKLEAG 355

CP001485_1511: domain 1 of 1, from 356 to 421: score 90.9, E = 1.4e-25
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks fla+lsHE+RTP+++++g+a++Ll+ +el+++q
CP001485_1 356 AKSAFLATLSHEIRTPMNGVLGTAQILLK---------DELTSKQ-- 391

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+ l ++++++e++ +L+n++Ld+s+ie+g
CP001485_1 392 ----------RQHLTSLYESGEHMMSLLNEILDYSKIEQG 421

CP001485_2560: domain 1 of 1, from 205 to 272: score 80.1, E = 1.6e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++ f+an+sHELRTP+t+++gy+e+ ++ ++ +
CP001485_2 205 MRRNFFANVSHELRTPMTVLQGYLEMTED---------PDVLAGP-- 240

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ ++ ++ ++++r++ L+n+lL+ls+iea
CP001485_2 241 --------MWSKAHGVMTEQLNRMNGLVNQLLTLSKIEAS 272

CP001485_1861: domain 1 of 1, from 211 to 275: score 79.8, E = 2e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ks fla++sHELRTPL+a++g++++L+ e ++ q
CP001485_1 211 SKSNFLAMMSHELRTPLNAVLGLIDILRG----------ESTSYQ-- 245

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e+le ++++ae ll +ind+Ldlsrie+g
CP001485_1 246 ----------VELLEQMENSAELLLIIINDILDLSRIESG 275

CP001485_0949: domain 1 of 1, from 282 to 347: score 75.1, E = 4.1e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k+ f++++sHELRTPL++I g++ +Ll+ t+ls eq
CP001485_0 282 DKTTFISTISHELRTPLNGIVGLSRMLLD---------TPLSGEQ-- 317

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+ l+ti +a l ++ nd+ d+ + +
CP001485_0 318 ----------RKHLQTINVSAVTLGNIFNDIIDMDKFDRR 347

CP001485_2744: domain 1 of 1, from 459 to 527: score 74.7, E = 5.5e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k+efla+ sHELRTPL++++g ae+L +++ ++ s+ +
CP001485_2 459 LKDEFLATTSHELRTPLHGMIGIAEALISGAN------GPISAAH-- 497

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ l++i+++++rl L++dlLd+ +++ g
CP001485_2 498 ----------KYQLDIIISSGQRLATLVDDLLDYHKMRYG 527

CP001485_1688: domain 1 of 1, from 651 to 716: score 71.4, E = 4.7e-20
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++ fla +sHELRTP++a++g+ e+L +s+e
CP001485_1 651 ARNHFLAVVSHELRTPIAAMLGLMEILAS---------RLKSSES-- 686

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +l ++++aerl +nd+Ld+s+iea+
CP001485_1 687 ----------QLLLTNAISSAERLKLHVNDILDFSKIEAQ 716

CP001485_0589: domain 1 of 1, from 131 to 196: score 60.6, E = 5.5e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a ++++l+HE+++PL ++rg+a+lL++ l+++ +
CP001485_0 131 AAKLLVRGLAHEIKNPLGGLRGAAQLLER----------MLPDPAL- 166

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
ey+++i+++a+rl+ L+++lL r ++
CP001485_0 167 ----------MEYTQIIIEQADRLRGLVDRLLGPQRPGEK 196

CP001485_1977: domain 1 of 1, from 212 to 277: score 58.5, E = 2.1e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++ +++H+LRTP+ I+ ae+L e + l+++q
CP001485_1 212 SNKALTNAIAHDLRTPIFRIQWQAEVLAE---------SQLNAKQ-- 247

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ + +i++++e ++ ++++lL ++++e++
CP001485_1 248 ----------QQQVASIIEDTEEMETMVDELLYYAKLEHP 277

CP001485_0291: domain 1 of 1, from 788 to 853: score 56.5, E = 7.6e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ks+fla++sH+L +PL+a r++a+ L e ++ +e
CP001485_0 788 SKSRFLAAVSHDLMQPLNAARLFASSLSE---------VAKEAEV-- 823

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ + i++++ ++Li+dlLd+sr+e+g
CP001485_0 824 ----------QKLAHHIESALGAAEDLISDLLDISRLESG 853

CP001485_1202: domain 1 of 1, from 125 to 191: score 56.4, E = 8.5e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++++a+l+H+ RTPL++ ++ya L + ++l++ +r
CP001485_1 125 SLGRMVASLAHQVRTPLSSAMLYAANLAA---------PNLPPATR- 161

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ +++ + ++ l++++nd+L +++ + +
CP001485_1 162 ----------ERFQSKLVDRLHDLEKQVNDMLLFAKGGDN 191

CP001485_1404: domain 1 of 1, from 373 to 441: score 52.4, E = 1.1e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++ a++sHEL++PL+aIr +a+ +++l t+++e
CP001485_1 373 VLGQMSASISHELNNPLAAIRSFADNGRRFLA------TNKPERA-- 411

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e l++i +er+ ++ ++l ++r +
CP001485_1 412 ----------EENLSRISALTERMAKISEQLKSFARKSTS 441

CP001485_0644: domain 1 of 1, from 247 to 309: score 50.2, E = 4.7e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++l+++sHELR PLt +r++ l+ + s+ +
CP001485_0 247 GQQRLLSDISHELRSPLTRLRMANALAMR---------KLGSSSE-- 282

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
le+i+ ea+rl+++i dlL lsr++ +
CP001485_0 283 -------------LERIDTEAQRLEQMIGDLLALSRMQIN 309

CP001485_0623: domain 2 of 2, from 226 to 286: score 49.3, E = 8.6e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++a++sH++RTPLt Ir+++e++ e+
CP001485_0 226 DRALLMAGISHDIRTPLTRIRLATEMMSP--------------ED-- 256

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ e+i++++e ++++i++++d+ + +
CP001485_0 257 ----------SYLAESIISDTEECNQIISQFMDYLKPVNR 286

CP001485_1814: domain 1 of 1, from 445 to 512: score 39.9, E = 4e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++e++a+++HE+++P ++I+g++el++ el ++ +
CP001485_1 445 ALGELTAGIAHEINNPTAVILGNTELIRFEL-------GADASRV-- 482

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e ++ il ++er++++ + lL++sr +
CP001485_1 483 ----------EEEIDAILLQIERIRNITRSLLQYSRQGGV 512


Histogram of all scores:
score obs exp (one = represents 9 sequences)
----- --- ---
-15 7 0|=
-14 18 0|==
-13 42 2|*====
-12 108 63|======*=====
-11 225 328|========================= *
-10 445 609|================================================== *
-9 499 629|======================================================== *
-8 495 470|====================================================*==
-7 342 296|================================*=====
-6 221 170|==================*======
-5 122 93|==========*===
-4 80 50|=====*===
-3 59 26|==*====
-2 38 13|=*===
-1 20 7|*==
0 14 3|*=
1 2 1|*
2 3 1|*
3 5 0|=
4 2 0|=
5 0 0|
6 1 0|=
7 1 0|=
8 0 0|
> 9 21 -|===


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 288.3959
P(chi-square) = 0

Total sequences searched: 2770

Whole sequence top hits:
tophits_s report:
Total hits: 17
Satisfying E cutoff: 17
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 16
Satisfying E cutoff: 16
Total memory: 27K


Acknowledgements:

This research is funded by:

Developed by: