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2 accessions found for Brucella melitensis ATCC 23457  

Data for CP001488  

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hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: CP001488.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
CP001488_0595 CDS_631710-629359 90.3 1.5e-25 1
CP001488_1532 CDS_1570198-1573305 89.7 2.3e-25 1
CP001488_0299 CDS_331167-332483 85.6 3.3e-24 1
CP001488_1975 CDS_2031789-2033594 72.5 1.7e-20 1
CP001488_1981 CDS_2037233-2039812 69.6 1.1e-19 1
CP001488_0560 CDS_590043-591872 63.3 6.7e-18 1
CP001488_1073 CDS_1116341-1115199 55.3 1.3e-15 1
CP001488_0592 CDS_622455-623858 48.8 8.9e-14 1
CP001488_0316 CDS_351602-348078 45.0 1.1e-12 1
CP001488_1071 CDS_1113636-1111312 42.4 5.6e-12 1
CP001488_0123 CDS_148776-150068 40.1 2.5e-11 1
CP001488_0996 CDS_1022880-1025576 39.5 3.9e-11 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CP001488_0595 1/1 543 612 .. 1 87 [] 90.3 1.5e-25
CP001488_1532 1/1 795 864 .. 1 87 [] 89.7 2.3e-25
CP001488_0299 1/1 200 267 .. 1 87 [] 85.6 3.3e-24
CP001488_1975 1/1 364 429 .. 1 87 [] 72.5 1.7e-20
CP001488_1981 1/1 627 695 .. 1 87 [] 69.6 1.1e-19
CP001488_0560 1/1 328 397 .. 1 87 [] 63.3 6.7e-18
CP001488_1073 1/1 135 199 .. 1 87 [] 55.3 1.3e-15
CP001488_0592 1/1 240 306 .. 1 87 [] 48.8 8.9e-14
CP001488_0316 1/1 801 866 .. 1 87 [] 45.0 1.1e-12
CP001488_1071 1/1 525 596 .. 1 87 [] 42.4 5.6e-12
CP001488_0123 1/1 209 275 .. 1 87 [] 40.1 2.5e-11
CP001488_0996 1/1 520 586 .. 1 87 [] 39.5 3.9e-11

Alignments of top-scoring domains:
CP001488_0595: domain 1 of 1, from 543 to 612: score 90.3, E = 1.5e-25
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
akseflan+sHELRTPL+aI+g++e+++++ + ++l+++
CP001488_0 543 AKSEFLANMSHELRTPLNAIIGFSEMIQAGTF------GPLGSDR-- 581

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
y+ey++ i+ +++ ll+ ind+Ld+s+ieag
CP001488_0 582 ---------YEEYINDIHTSGNFLLNVINDILDMSKIEAG 612

CP001488_1532: domain 1 of 1, from 795 to 864: score 89.7, E = 2.3e-25
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+k+efla +sHE+RTPL+aI+g++el+ + + ++ + +
CP001488_1 795 QKTEFLARISHEIRTPLNAIIGFSELMAD------EKFGPIGNDR-- 833

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
yr+yl+ i r++++ l+L+ndlLd+s+ieag
CP001488_1 834 ---------YRDYLRDINRSGNHVLALVNDLLDISKIEAG 864

CP001488_0299: domain 1 of 1, from 200 to 267: score 85.6, E = 3.3e-24
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++s+f+an+sHELRTPL+++rg++e+L+ +++++ ++
CP001488_0 200 MRSDFIANASHELRTPLASLRGFIETLQG---------PARNDAAAR 237

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++l++++++aer++rLi+dlL lsr+e
CP001488_0 238 ----------DRFLDIMQKQAERMSRLIDDLLSLSRLEMR 267

CP001488_1975: domain 1 of 1, from 364 to 429: score 72.5, E = 1.7e-20
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a + f+a++sHEL++PLt++r ++e+L ++++e r
CP001488_1 364 AIESFAADVSHELKNPLTSLRSAVETLPL----------AKTDESR- 399

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l++i+++++rl+rLi d+ d sr++a+
CP001488_1 400 ----------KRLLDVIQHDVRRLDRLITDISDASRLDAE 429

CP001488_1981: domain 1 of 1, from 627 to 695: score 69.6, E = 1.1e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k++f+ ++s ELR PLt I+g++elL++ + + l+e q
CP001488_1 627 IKNDFVQHVSYELRSPLTNIIGFTELLQT------PAFGSLNERQ-- 665

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
eyl+ i ++ ll ++nd+Ldl+ +ag
CP001488_1 666 ----------LEYLDHISTSSSVLLTIVNDILDLATVDAG 695

CP001488_0560: domain 1 of 1, from 328 to 397: score 63.3, E = 6.7e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k+++la++sHELRTPL++I+g++++L + ++l ++ +
CP001488_0 328 GKGRLLATVSHELRTPLNSIIGFSDMLTH------EIGGKLASDRQ- 367

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
rey i++++++ll+L+n +Ld sr+e+g
CP001488_0 368 ----------REYAGLIHQSGHYLLELVNAVLDNSRLETG 397

CP001488_1073: domain 1 of 1, from 135 to 199: score 55.3, E = 1.3e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ + ++++l+HE+++PL++Irg+a+lL+ s+e+
CP001488_1 135 SVTGLASMLAHEIKNPLSGIRGAAQLLEQ----------VVSDED-- 169

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r + + i +e++r+ +L++++ +s +
CP001488_1 170 ----------RALARLITEETDRIVSLVDRMEVFSDERPI 199

CP001488_0592: domain 1 of 1, from 240 to 306: score 48.8, E = 8.9e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ + n++H+L+TPLt +r ae +l +e+ e++
CP001488_0 240 GLKQVSDNIAHDLKTPLTRLRNRAEEALG---------GEKVEPE-- 275

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
yr +le i+ e+++l r n +L +sr+eag
CP001488_0 276 ---------YRAALEDIIGESDQLIRTFNAILMISRLEAG 306

CP001488_0316: domain 1 of 1, from 801 to 866: score 45.0, E = 1.1e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k++fla++ H++ +PL+a r+y+ +L e +l+ ++
CP001488_0 801 GKTRFLAAAGHDILQPLNAARLYSTALAE----------KLGRSET- 836

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e+ + i++++e ++++ +Ld+sr+++g
CP001488_0 837 ----------SEFARNIDSSLEAVEAILGMVLDISRLDTG 866

CP001488_1071: domain 1 of 1, from 525 to 596: score 42.4, E = 5.6e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a + ++ ++HE+++PLt I++ ae +++++ ++ + + e
CP001488_1 525 AWADVARRIAHEIKNPLTPIQLSAERIRRRY----GKVITEDREV-- 565

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + ++ti+r++ + r+++++ ++r+ +
CP001488_1 566 ---------FDQCTDTIIRQVGDIGRMVDEFSAFARMPKP 596

CP001488_0123: domain 1 of 1, from 209 to 275: score 40.1, E = 2.5e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++ ++a+++HEL TPL++I + ++ +++ +++++
CP001488_0 209 ALDGLAAAAAHELGTPLATIALVVKEMQR--------AHTKDPGL-- 245

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e + ++++++r+++++++l ls +++
CP001488_0 246 ----------EEDIALLHSQTQRCREILQRLTSLSSEGEE 275

CP001488_0996: domain 1 of 1, from 520 to 586: score 39.5, E = 3.9e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a ++++ +++H++++ LtaI++ ++lLl++ + +s++
CP001488_0 520 AVGQLAGGIAHDFNNVLTAIIMSSDLLLTN--------HRASDPS-- 556

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ i++ a+r +L+++lL +sr ++
CP001488_0 557 ----------FPDIMNIKQNANRAASLVRQLLAFSRRQTL 586


Histogram of all scores:
score obs exp (one = represents 7 sequences)
----- --- ---
-15 2 0|=
-14 19 0|===
-13 40 1|*=====
-12 140 47|======*=============
-11 229 244|================================= *
-10 356 453|=================================================== *
-9 397 468|========================================================= *
-8 324 350|=============================================== *
-7 242 221|===============================*===
-6 133 127|==================*
-5 79 69|=========*==
-4 42 37|=====*
-3 19 19|==*
-2 11 10|=*
-1 7 5|*
0 4 2|*
1 2 1|*
2 0 0|
3 2 0|=
> 4 16 -|===


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 222.3400
P(chi-square) = 3.18e-311

Total sequences searched: 2064

Whole sequence top hits:
tophits_s report:
Total hits: 12
Satisfying E cutoff: 12
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 12
Satisfying E cutoff: 12
Total memory: 25K


Acknowledgements:

This research is funded by:

Developed by: