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Thermotogae
Classification of phyla is from NCBI page
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264 projects found  

1 accessions found for Escherichia coli BL21(DE3)  

Data for CP001509  

Available Atlases
Other Plots
hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: CP001509.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
CP001509_2548 CDS_2747646-2750402 100.1 5e-28 1
CP001509_0345 CDS_383291-384586 91.0 2e-25 1
CP001509_2199 CDS_2362262-2365855 81.6 8.9e-23 1
CP001509_0989 CDS_1060466-1057722 80.7 1.6e-22 1
CP001509_2066 CDS_2210189-2207388 80.6 1.8e-22 1
CP001509_2979 CDS_3221525-3219189 78.9 5.3e-22 1
CP001509_2067 CDS_2210404-2212230 76.4 2.7e-21 1
CP001509_2368 CDS_2556903-2555476 75.4 5.2e-21 1
CP001509_1932 CDS_2061797-2063200 69.8 2e-19 1
CP001509_3690 CDS_4012897-4011524 66.6 1.6e-18 1
CP001509_4155 CDS_4553997-4555421 62.4 2.4e-17 1
CP001509_3772 CDS_4109972-4111348 62.1 2.9e-17 1
CP001509_0509 CDS_553452-552004 61.0 6.2e-17 1
CP001509_2802 CDS_3037921-3039270 60.7 7.8e-17 1
CP001509_3647 CDS_3963037-3961988 59.7 1.5e-16 1
CP001509_0626 CDS_684291-681604 59.6 1.5e-16 1
CP001509_3159 CDS_3396248-3394896 55.0 3.1e-15 1
CP001509_1835 CDS_1943299-1941941 52.3 1.7e-14 1
CP001509_3873 CDS_4240351-4239260 45.0 2.1e-12 1
CP001509_1534 CDS_1628079-1629380 42.4 1.2e-11 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CP001509_2548 1/1 292 357 .. 1 87 [] 100.1 5e-28
CP001509_0345 1/1 203 269 .. 1 87 [] 91.0 2e-25
CP001509_2199 1/1 711 777 .. 1 87 [] 81.6 8.9e-23
CP001509_0989 1/1 443 508 .. 1 87 [] 80.7 1.6e-22
CP001509_2066 1/1 453 518 .. 1 87 [] 80.6 1.8e-22
CP001509_2979 1/1 282 347 .. 1 87 [] 78.9 5.3e-22
CP001509_2067 1/1 388 453 .. 1 87 [] 76.4 2.7e-21
CP001509_2368 1/1 249 317 .. 1 87 [] 75.4 5.2e-21
CP001509_1932 1/1 240 304 .. 1 87 [] 69.8 2e-19
CP001509_3690 1/1 238 300 .. 1 87 [] 66.6 1.6e-18
CP001509_4155 1/1 255 320 .. 1 87 [] 62.4 2.4e-17
CP001509_3772 1/1 237 303 .. 1 87 [] 62.1 2.9e-17
CP001509_0509 1/1 261 327 .. 1 87 [] 61.0 6.2e-17
CP001509_2802 1/1 236 302 .. 1 87 [] 60.7 7.8e-17
CP001509_3647 1/1 129 186 .. 1 79 [. 59.7 1.5e-16
CP001509_0626 1/1 664 731 .. 1 87 [] 59.6 1.5e-16
CP001509_3159 1/1 233 293 .. 1 87 [] 55.0 3.1e-15
CP001509_1835 1/1 235 301 .. 1 87 [] 52.3 1.7e-14
CP001509_3873 1/1 142 202 .. 1 87 [] 45.0 2.1e-12
CP001509_1534 1/1 211 271 .. 1 87 [] 42.4 1.2e-11

Alignments of top-scoring domains:
CP001509_2548: domain 1 of 1, from 292 to 357: score 100.1, E = 5e-28
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
kseflan+sHELRTPL++++g++ l l+ tel++ q
CP001509_2 292 IKSEFLANMSHELRTPLNGVIGFTRLTLK---------TELTPTQ-- 327

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+ l+ti+r+a+ ll++ind+Ld+s++eag
CP001509_2 328 ----------RDHLNTIERSANNLLAIINDVLDFSKLEAG 357

CP001509_0345: domain 1 of 1, from 203 to 269: score 91.0, E = 2e-25
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++ f+an+sHELRTPLt+++gy+e++ e ++l r
CP001509_0 203 ARRNFFANVSHELRTPLTVLQGYLEMMDE---------QPLEGAVR- 239

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l+t++++++r++ L+ +lL+ls+iea
CP001509_0 240 ----------EKALHTMREQTQRMEGLVKQLLTLSKIEAA 269

CP001509_2199: domain 1 of 1, from 711 to 777: score 81.6, E = 8.9e-23
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks+fla++sHE+RTP+++I+g++elL + ls eqr
CP001509_2 711 AKSQFLATMSHEIRTPISSIMGFLELLSG---------SGLSKEQR- 747

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e+++ ++ +++ll Li ++Ld +ie+g
CP001509_2 748 ----------VEAISLAYATGQSLLGLIGEILDVDKIESG 777

CP001509_0989: domain 1 of 1, from 443 to 508: score 80.7, E = 1.6e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks fla++sHE+RTPL +I+g+a+lL + ++ q
CP001509_0 443 AKSAFLAAMSHEIRTPLYGILGTAQLLAD---------NPALNAQ-- 478

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+ l+ i +++e+ll ++nd+Ld+s ieag
CP001509_0 479 ----------RDDLRAITDSGESLLTILNDILDYSAIEAG 508

CP001509_2066: domain 1 of 1, from 453 to 518: score 80.6, E = 1.8e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ks fla++sHELRTPL +I+g+++lL++ el+
CP001509_2 453 SKSMFLATVSHELRTPLYGIIGNLDLLQT---------KELPKGV-- 488

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ + +++ ll++i+d+Ld+s+ie++
CP001509_2 489 ----------DRLVTAMNNSSSLLLKIISDILDFSKIESE 518

CP001509_2979: domain 1 of 1, from 282 to 347: score 78.9, E = 5.3e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k+ f++++sHELRTPL++I g++ +Ll+ tel++eq
CP001509_2 282 DKTTFISTISHELRTPLNGIVGLSRILLD---------TELTAEQ-- 317

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++yl+ti+ +a l ++ nd+ d+ ++e
CP001509_2 318 ----------EKYLKTIHVSAVTLGNIFNDIIDMDKMERR 347

CP001509_2067: domain 1 of 1, from 388 to 453: score 76.4, E = 2.7e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++e++a+++HE R+PLtaIrgy+++L+ ++ ++ +
CP001509_2 388 TLGELMAGVAHEVRNPLTAIRGYVQILRQ---------QTSDPIH-- 423

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+eyl+++l+e++++++ i++lL++sr ++
CP001509_2 424 ----------QEYLSVVLKEIDSINKVIQQLLEFSRPRHS 453

CP001509_2368: domain 1 of 1, from 249 to 317: score 75.4, E = 5.2e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +fl++lsHEL+TPL+++r +elL +++ ++l++eq
CP001509_2 249 QRHQFLRHLSHELKTPLASMREGTELLADQV------VGPLTPEQ-- 287

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e +++++++++ l++Li++lLd+ r +a
CP001509_2 288 ----------KEVVSILDSSSRNLQKLIEQLLDYNRKQAD 317

CP001509_1932: domain 1 of 1, from 240 to 304: score 69.8, E = 2e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+a++sHELRTPL+++rg +e++++++ + ++e+
CP001509_1 240 MRRDFMADISHELRTPLAVLRGELEAIQDGV-------RKFTPET-- 277

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +++ e+ l +L++dl +ls ++g
CP001509_1 278 -------------VASLQAEVGTLTKLVDDLHQLSMSDEG 304

CP001509_3690: domain 1 of 1, from 238 to 300: score 66.6, E = 1.6e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++++l+++sHELRTPLt +++ + lL++ +++
CP001509_3 238 SQQRLLSDISHELRTPLTRLQLGTALLRR---------RSGESKE-- 273

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
le+i+ ea+rl+++indlL +sr ++
CP001509_3 274 -------------LERIETEAQRLDSMINDLLVMSRNQQK 300

CP001509_4155: domain 1 of 1, from 255 to 320: score 62.4, E = 2.4e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ + +l HEL+ PL+aIrg+ae+L+e ++ +e
CP001509_4 255 YIEQYVYALTHELKSPLAAIRGAAEILRE---------GPPPEVV-- 290

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++++ il + r+++L++ lL +r+e+
CP001509_4 291 ----------ARFTDNILTQNARMQALVETLLRQARLENR 320

CP001509_3772: domain 1 of 1, from 237 to 303: score 62.1, E = 2.9e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++ ++a+++HE+R+PL++I+g+a+ e +++++ e
CP001509_3 237 ALGHLAAGVAHEIRNPLSSIKGLAKYFAE--------RAPAGGEA-- 273

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ +++ +ea+rl+r +++lL+l r +
CP001509_3 274 ----------HQLAQVMAKEADRLNRVVSELLELVRPTHL 303

CP001509_0509: domain 1 of 1, from 261 to 327: score 61.0, E = 6.2e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++s f a+++HE+RTP+t +++ +e++l + +s +++
CP001509_0 261 RQSNFSADIAHEIRTPITNLITQTEIALS---------QSRSQKEL- 297

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ l + l+e+ r+ ++++d+L l++++++
CP001509_0 298 ----------EDVLYSNLEELTRMAKMVSDMLFLAQADNN 327

CP001509_2802: domain 1 of 1, from 236 to 302: score 60.7, E = 7.8e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++f+++++HELR PLta++ +e+++ ++ +++ r
CP001509_2 236 RERRFTSDAAHELRSPLTALKVQTEVAQL---------SDDDPQAR- 272

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l +++ ++r rL+++lL+lsr+++
CP001509_2 273 ----------KKALLQLHSGIDRATRLVDQLLTLSRLDSL 302

CP001509_3647: domain 1 of 1, from 129 to 186: score 59.7, E = 1.5e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a ++++++l+HE+++PL ++rg+a+lL + +l+++ +
CP001509_3 129 AARDLVRGLAHEIKNPLGGLRGAAQLLSK----------ALPDPSL- 164

peLRledpeyreyletilreaerllrLindlL<-*
ey+++i+++a+rl++L+++lL
CP001509_3 165 ----------LEYTKVIIEQADRLRNLVDRLL 186

CP001509_0626: domain 1 of 1, from 664 to 731: score 59.6, E = 1.5e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +la+lsH+LRTPLt++ g ae+L +l + ++++
CP001509_0 664 IRNALLAALSHDLRTPLTVLFGQAEILTLDL-------ASEGSPH-- 701

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ + i++ + rL+n+lLd++ri++g
CP001509_0 702 ----------ARQASEIRQHVLNTTRLVNNLLDMARIQSG 731

CP001509_3159: domain 1 of 1, from 233 to 293: score 55.0, E = 3.1e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ ++a++sH+LRTPLt Ir+++e++ e ++
CP001509_3 233 DRTLLMAGVSHDLRTPLTRIRLATEMMSE---------QD------- 263

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ e+i +++e ++++i+++ d+ r +++
CP001509_3 264 ----------GYLAESINKDIEECNAIIEQFIDYLRTGQE 293

CP001509_1835: domain 1 of 1, from 235 to 301: score 52.3, E = 1.7e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++s+f+ +l+HELRTP++a++g ++ l +++s +
CP001509_1 235 RLSQFADDLAHELRTPINALLGQNQVTLS---------QTRSIAE-- 270

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
y++ + ++e+e ++rL +++L l+r++ +
CP001509_1 271 ---------YQKTIAGNIEELENISRLTENILFLARADKN 301

CP001509_3873: domain 1 of 1, from 142 to 202: score 45.0, E = 2.1e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ f+a+++HELRTPL+++r+++elL + t+
CP001509_3 142 NERLFTADVAHELRTPLAGVRLHLELLAK---------TH------- 172

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + + ++++ + +++lL+l+r+++
CP001509_3 173 ----------HIDVAPLVARLDQMMESVSQLLQLARAGQS 202

CP001509_1534: domain 1 of 1, from 211 to 271: score 42.4, E = 1.2e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+k +++ +++HELRTPL +r +e+ + ls+ +
CP001509_1 211 SKKQLIDGIAHELRTPLVRLRYRLEMSDN-----------LSAAE-- 244

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + r++ +l++Li++lL+++r++ +
CP001509_1 245 -------------SQALNRDISQLEALIEELLTYARLDRP 271


Histogram of all scores:
score obs exp (one = represents 14 sequences)
----- --- ---
-16 1 0|=
-15 2 0|=
-14 16 0|==
-13 49 3|*===
-12 181 95|======*======
-11 440 493|================================ *
-10 706 914|=================================================== *
-9 790 944|========================================================= *
-8 707 707|==================================================*
-7 512 445|===============================*=====
-6 305 256|==================*===
-5 197 140|=========*=====
-4 86 75|=====*=
-3 51 39|==*=
-2 27 20|=*
-1 34 10|*==
0 15 5|*=
1 7 2|*
2 9 1|*
3 2 0|=
4 0 0|
> 5 22 -|==


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 268.4384
P(chi-square) = 0

Total sequences searched: 4159

Whole sequence top hits:
tophits_s report:
Total hits: 20
Satisfying E cutoff: 20
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 20
Satisfying E cutoff: 20
Total memory: 28K


Acknowledgements:

This research is funded by:

Developed by: