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2 accessions found for Brucella microti CCM 4915  

Data for CP001578  

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hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: CP001578.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
CP001578_0592 CDS_613856-611505 90.3 1.5e-25 1
CP001578_1559 CDS_1558186-1561293 89.7 2.4e-25 1
CP001578_0294 CDS_311890-313206 85.6 3.4e-24 1
CP001578_2029 CDS_2022875-2024680 72.5 1.8e-20 1
CP001578_2037 CDS_2028319-2030898 69.6 1.1e-19 1
CP001578_0553 CDS_572168-573997 63.3 6.9e-18 1
CP001578_1084 CDS_1102629-1101526 55.3 1.3e-15 1
CP001578_0589 CDS_604601-606004 48.8 9.1e-14 1
CP001578_1082 CDS_1099963-1097639 42.4 5.8e-12 1
CP001578_0132 CDS_150427-151719 40.1 2.6e-11 1
CP001578_1000 CDS_1008213-1011050 39.5 4e-11 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CP001578_0592 1/1 543 612 .. 1 87 [] 90.3 1.5e-25
CP001578_1559 1/1 795 864 .. 1 87 [] 89.7 2.4e-25
CP001578_0294 1/1 200 267 .. 1 87 [] 85.6 3.4e-24
CP001578_2029 1/1 364 429 .. 1 87 [] 72.5 1.8e-20
CP001578_2037 1/1 627 695 .. 1 87 [] 69.6 1.1e-19
CP001578_0553 1/1 328 397 .. 1 87 [] 63.3 6.9e-18
CP001578_1084 1/1 122 186 .. 1 87 [] 55.3 1.3e-15
CP001578_0589 1/1 240 306 .. 1 87 [] 48.8 9.1e-14
CP001578_1082 1/1 525 596 .. 1 87 [] 42.4 5.8e-12
CP001578_0132 1/1 209 275 .. 1 87 [] 40.1 2.6e-11
CP001578_1000 1/1 567 633 .. 1 87 [] 39.5 4e-11

Alignments of top-scoring domains:
CP001578_0592: domain 1 of 1, from 543 to 612: score 90.3, E = 1.5e-25
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
akseflan+sHELRTPL+aI+g++e+++++ + ++l+++
CP001578_0 543 AKSEFLANMSHELRTPLNAIIGFSEMIQAGTF------GPLGSDR-- 581

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
y+ey++ i+ +++ ll+ ind+Ld+s+ieag
CP001578_0 582 ---------YEEYINDIHTSGNFLLNVINDILDMSKIEAG 612

CP001578_1559: domain 1 of 1, from 795 to 864: score 89.7, E = 2.4e-25
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+k+efla +sHE+RTPL+aI+g++el+ + + ++ + +
CP001578_1 795 QKTEFLARISHEIRTPLNAIIGFSELMAD------EKFGPIGNDR-- 833

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
yr+yl+ i r++++ l+L+ndlLd+s+ieag
CP001578_1 834 ---------YRDYLRDINRSGNHVLALVNDLLDISKIEAG 864

CP001578_0294: domain 1 of 1, from 200 to 267: score 85.6, E = 3.4e-24
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++s+f+an+sHELRTPL+++rg++e+L+ +++++ ++
CP001578_0 200 MRSDFIANASHELRTPLASLRGFIETLQG---------PARNDAAAR 237

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++l++++++aer++rLi+dlL lsr+e
CP001578_0 238 ----------DRFLDIMQKQAERMSRLIDDLLSLSRLEMR 267

CP001578_2029: domain 1 of 1, from 364 to 429: score 72.5, E = 1.8e-20
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a + f+a++sHEL++PLt++r ++e+L ++++e r
CP001578_2 364 AIESFAADVSHELKNPLTSLRSAVETLPL----------AKTDESR- 399

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l++i+++++rl+rLi d+ d sr++a+
CP001578_2 400 ----------KRLLDVIQHDVRRLDRLITDISDASRLDAE 429

CP001578_2037: domain 1 of 1, from 627 to 695: score 69.6, E = 1.1e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k++f+ ++s ELR PLt I+g++elL++ + + l+e q
CP001578_2 627 IKNDFVQHVSYELRSPLTNIIGFTELLQT------PAFGSLNERQ-- 665

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
eyl+ i ++ ll ++nd+Ldl+ +ag
CP001578_2 666 ----------LEYLDHISTSSSVLLTIVNDILDLATVDAG 695

CP001578_0553: domain 1 of 1, from 328 to 397: score 63.3, E = 6.9e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k+++la++sHELRTPL++I+g++++L + ++l ++ +
CP001578_0 328 GKGRLLATVSHELRTPLNSIIGFSDMLTH------EIGGKLASDRQ- 367

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
rey i++++++ll+L+n +Ld sr+e+g
CP001578_0 368 ----------REYAGLIHQSGHYLLELVNAVLDNSRLETG 397

CP001578_1084: domain 1 of 1, from 122 to 186: score 55.3, E = 1.3e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ + ++++l+HE+++PL++Irg+a+lL+ s+e+
CP001578_1 122 SVTGLASMLAHEIKNPLSGIRGAAQLLEQ----------VVSDED-- 156

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r + + i +e++r+ +L++++ +s +
CP001578_1 157 ----------RALARLITEETDRIVSLVDRMEVFSDERPI 186

CP001578_0589: domain 1 of 1, from 240 to 306: score 48.8, E = 9.1e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ + n++H+L+TPLt +r ae +l +e+ e++
CP001578_0 240 GLKQVSDNIAHDLKTPLTRLRNRAEEALG---------GEKVEPE-- 275

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
yr +le i+ e+++l r n +L +sr+eag
CP001578_0 276 ---------YRAALEDIIGESDQLIRTFNAILMISRLEAG 306

CP001578_1082: domain 1 of 1, from 525 to 596: score 42.4, E = 5.8e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a + ++ ++HE+++PLt I++ ae +++++ ++ + + e
CP001578_1 525 AWADVARRIAHEIKNPLTPIQLSAERIRRRY----GKVITEDREV-- 565

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + ++ti+r++ + r+++++ ++r+ +
CP001578_1 566 ---------FDQCTDTIIRQVGDIGRMVDEFSAFARMPKP 596

CP001578_0132: domain 1 of 1, from 209 to 275: score 40.1, E = 2.6e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++ ++a+++HEL TPL++I + ++ +++ +++++
CP001578_0 209 ALDGLAAAAAHELGTPLATIALVVKEMQR--------AHTKDPGL-- 245

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e + ++++++r+++++++l ls +++
CP001578_0 246 ----------EEDIALLHSQTQRCREILQRLTSLSSEGEE 275

CP001578_1000: domain 1 of 1, from 567 to 633: score 39.5, E = 4e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a ++++ +++H++++ LtaI++ ++lLl++ + +s++
CP001578_1 567 AVGQLAGGIAHDFNNVLTAIIMSSDLLLTN--------HRASDPS-- 603

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ i++ a+r +L+++lL +sr ++
CP001578_1 604 ----------FPDIMNIKQNANRAASLVRQLLAFSRRQTL 633


Histogram of all scores:
score obs exp (one = represents 8 sequences)
----- --- ---
-15 2 0|=
-14 17 0|===
-13 44 1|*=====
-12 138 48|=====*============
-11 244 251|===============================*
-10 349 466|============================================ *
-9 424 481|===================================================== *
-8 334 360|========================================== *
-7 245 227|============================*==
-6 137 130|================*=
-5 77 71|========*=
-4 46 38|====*=
-3 22 20|==*
-2 12 10|=*
-1 7 5|*
0 4 2|*
1 2 1|*
2 0 0|
3 1 0|=
> 4 15 -|==


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 208.2515
P(chi-square) = 1.438e-38

Total sequences searched: 2120

Whole sequence top hits:
tophits_s report:
Total hits: 11
Satisfying E cutoff: 11
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 11
Satisfying E cutoff: 11
Total memory: 25K


Acknowledgements:

This research is funded by:

Developed by: