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Classification of phyla is from NCBI page
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264 projects found  

4 accessions found for Yersinia pestis Z176003  

Data for CP001593  

Available Atlases
Other Plots
hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: CP001593.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
CP001593_2820 CDS_3620993-3619677 88.2 1.1e-24 1
CP001593_0221 CDS_255558-252739 86.8 2.6e-24 1
CP001593_2977 CDS_3821993-3824785 85.9 4.5e-24 1
CP001593_1121 CDS_1445044-1447824 79.3 3.3e-22 1
CP001593_3212 CDS_4120344-4122680 75.7 3.7e-21 1
CP001593_1818 CDS_2337081-2338466 69.5 2e-19 1
CP001593_2416 CDS_3121683-3123110 68.8 3.2e-19 1
CP001593_2649 CDS_3415280-3416824 67.1 1e-18 1
CP001593_2472 CDS_3192824-3191709 67.0 1.1e-18 1
CP001593_0066 CDS_83612-82236 63.6 9.6e-18 1
CP001593_0022 CDS_32877-31828 62.4 2.1e-17 1
CP001593_2371 CDS_3071507-3068781 61.1 5e-17 1
CP001593_0828 CDS_1072253-1073671 58.1 3.6e-16 1
CP001593_2640 CDS_3402587-3401238 53.9 5.3e-15 1
CP001593_0117 CDS_148379-149731 53.2 8.6e-15 1
CP001593_1066 CDS_1372604-1374418 53.0 9.9e-15 1
CP001593_3251 CDS_4167254-4166187 46.9 5.4e-13 1
CP001593_2199 CDS_2837931-2835376 40.4 3.6e-11 1
CP001593_1563 CDS_2028214-2026958 36.2 5.5e-10 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CP001593_2820 1/1 203 269 .. 1 87 [] 88.2 1.1e-24
CP001593_0221 1/1 397 462 .. 1 87 [] 86.8 2.6e-24
CP001593_2977 1/1 291 356 .. 1 87 [] 85.9 4.5e-24
CP001593_1121 1/1 448 513 .. 1 87 [] 79.3 3.3e-22
CP001593_3212 1/1 282 347 .. 1 87 [] 75.7 3.7e-21
CP001593_1818 1/1 238 304 .. 1 87 [] 69.5 2e-19
CP001593_2416 1/1 249 317 .. 1 87 [] 68.8 3.2e-19
CP001593_2649 1/1 280 350 .. 1 87 [] 67.1 1e-18
CP001593_2472 1/1 237 301 .. 1 87 [] 67.0 1.1e-18
CP001593_0066 1/1 238 300 .. 1 87 [] 63.6 9.6e-18
CP001593_0022 1/1 129 194 .. 1 87 [] 62.4 2.1e-17
CP001593_2371 1/1 665 732 .. 1 87 [] 61.1 5e-17
CP001593_0828 1/1 255 320 .. 1 87 [] 58.1 3.6e-16
CP001593_2640 1/1 228 291 .. 1 87 [] 53.9 5.3e-15
CP001593_0117 1/1 233 293 .. 1 87 [] 53.2 8.6e-15
CP001593_1066 1/1 370 436 .. 1 87 [] 53.0 9.9e-15
CP001593_3251 1/1 136 196 .. 1 87 [] 46.9 5.4e-13
CP001593_2199 1/1 497 559 .. 1 87 [] 40.4 3.6e-11
CP001593_1563 1/1 195 255 .. 1 87 [] 36.2 5.5e-10

Alignments of top-scoring domains:
CP001593_2820: domain 1 of 1, from 203 to 269: score 88.2, E = 1.1e-24
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++ f+an+sHELRTPLt+++gy+e++ + +el + r
CP001593_2 203 ARRNFFANVSHELRTPLTVLQGYLEMMHD---------QELAGPLR- 239

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++l t++++++r++ L+ +lL+lsriea
CP001593_2 240 ----------DKALGTMQEQTKRMDGLVKQLLTLSRIEAA 269

CP001593_0221: domain 1 of 1, from 397 to 462: score 86.8, E = 2.6e-24
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ks+ l ++sHE+RTPL++ +g++elL++ t+l++ q
CP001593_0 397 RKSDHLTTISHEIRTPLNGALGAVELLQN---------TPLDAGQ-- 432

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ et+++++ +ll++in+lLd+srie+g
CP001593_0 433 ----------MRLAETAHQCSLSLLAIINNLLDFSRIESG 462

CP001593_2977: domain 1 of 1, from 291 to 356: score 85.9, E = 4.5e-24
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
kseflan+sHELRTPL++++g++ l+ t l++ q
CP001593_2 291 IKSEFLANMSHELRTPLNGVIGFTRQTLK---------TSLTPTQ-- 326

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+yl+ti+r+a+ ll +ind+Ld+s++ea
CP001593_2 327 ----------TDYLQTIQRSANNLLCIINDVLDFSKLEAD 356

CP001593_1121: domain 1 of 1, from 448 to 513: score 79.3, E = 3.3e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ks fla++sHELRTPL +I+g+++lL++ el+
CP001593_1 448 SKSMFLATVSHELRTPLYGIIGNLDLLQT---------KELPQGV-- 483

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ + +++ ll++i+d+Ld+s+ie++
CP001593_1 484 ----------DRLVTAMNNSSGLLLKIISDILDFSKIESE 513

CP001593_3212: domain 1 of 1, from 282 to 347: score 75.7, E = 3.7e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k+ f++++sHELRTPL++I g++ +Ll+ tel++eq
CP001593_3 282 DKTTFISTISHELRTPLNGIVGLSRILLD---------TELDAEQ-- 317

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+yl+ti+ +a l ++ nd+ ++ ++e
CP001593_3 318 ----------LKYLKTIHVSAITLGNIFNDIIEMDKLERR 347

CP001593_1818: domain 1 of 1, from 238 to 304: score 69.5, E = 2e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++ f a+++HELRTPLt ++g ++l l ++ ++
CP001593_1 238 QLESFNADVAHELRTPLTNLMGQTQLGLS---------RKRETHEL- 274

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++le+ l+e+er+ +++nd+L ls ++ag
CP001593_1 275 ----------EDLLESNLEELERMTSIVNDMLFLSHAQAG 304

CP001593_2416: domain 1 of 1, from 249 to 317: score 68.8, E = 3.2e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ efl+++sHEL+TPL+++r +elL +e+ ++l+ +q
CP001593_2 249 QRHEFLRHISHELKTPLASMREGTELLADEVA------GPLTQDQ-- 287

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e + ++++++++l++Li++lLd+ r a
CP001593_2 288 ----------QEVVAILDHSSRHLQQLIEQLLDYNRKLAD 317

CP001593_2649: domain 1 of 1, from 280 to 350: score 67.1, E = 1e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ f+ +sHEL+TPLt I +yae+L+e l+ ++ ++
CP001593_2 280 QQVSFVGQVSHELKTPLTNITLYAEMLQE-----LQPEQSVPPTAE- 320

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++yle+il+e++rl+rLi+++L ++++
CP001593_2 321 ----------QRYLEVILNESQRLSRLIQNILSFTKAPKL 350

CP001593_2472: domain 1 of 1, from 237 to 301: score 67.0, E = 1.1e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+a++sHELRTPL+++rg +e+L+++l ++e
CP001593_2 237 MRRDFMADVSHELRTPLAVLRGELEALQDGL-------RQPTPES-- 274

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
l++++ e+ l +L+ndl +ls+ + g
CP001593_2 275 -------------LSSLQAEVAILTKLVNDLHQLSQSDRG 301

CP001593_0066: domain 1 of 1, from 238 to 300: score 63.6, E = 9.6e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++++++++sHELRTPLt +++++ l+++ + ++
CP001593_0 238 AQQRLISDISHELRTPLTRLQLATALMRR---------RHGEGKE-- 273

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
le+i+ ea+rl+++indlL lsr ++
CP001593_0 274 -------------LERIEMEAQRLDSMINDLLVLSRSQHK 300

CP001593_0022: domain 1 of 1, from 129 to 194: score 62.4, E = 2.1e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a ++++++l+HE+++PL ++rg+a+lL + +l+++ +
CP001593_0 129 AARDLVRGLAHEIKNPLGGLRGAAQLLAK----------ALPDPAL- 164

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
ey+++i+++a+rl++L+++lL r ++
CP001593_0 165 ----------LEYTQVIIEQADRLRNLVDRLLGPQRPGQH 194

CP001593_2371: domain 1 of 1, from 665 to 732: score 61.1, E = 5e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +la+lsH+LRTPLt++ g ae+L +l ++ ++ +
CP001593_2 665 LRNSLLAALSHDLRTPLTVLFGQAEILTLDL-------AAEGSRH-- 702

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + i++++ + rL+n+lLd++ri++g
CP001593_2 703 ----------APQANQIRQQVLSTTRLVNNLLDMARIQSG 732

CP001593_0828: domain 1 of 1, from 255 to 320: score 58.1, E = 3.6e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ + +l HEL+ PL+aI+g+aelL+e ++ +e
CP001593_0 255 YIEQYVHTLTHELKSPLAAISGAAELLRE---------SPPPETA-- 290

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l i++++ r+++L++ +L +r+e+
CP001593_0 291 ----------QRFLINIEQQSARIQQLVDKMLVQARLESR 320

CP001593_2640: domain 1 of 1, from 228 to 291: score 53.9, E = 5.3e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++++l ++sHELR PL+ +++++ l ++++++ +
CP001593_2 228 AREQLLHDVSHELRSPLARLQLAIGL------------AHQNPDNV- 261

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+l++i++e+erl+++i +lL lsr+e+
CP001593_2 262 ----------DNALQRIEHESERLDKMIGELLALSRAENH 291

CP001593_0117: domain 1 of 1, from 233 to 293: score 53.2, E = 8.6e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ ++a++sH+LRTPLt Ir+++e++ e ++
CP001593_0 233 DRTLLMAGVSHDLRTPLTRIRLATEMMSE--------------DD-- 263

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + e+i +++e ++++i+++ d+ r +++
CP001593_0 264 ----------AYLSESINKDIEECNAIIEQFIDYLRTGQE 293

CP001593_1066: domain 1 of 1, from 370 to 436: score 53.0, E = 9.9e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a + ++a+++HE+R+PL++I+g+a+ + +++++e+
CP001593_1 370 AIGNLAAGVAHEIRNPLSSIKGFAKYFEG--------HSPQGSEE-- 406

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e+ +++++e++rl+r + +lL l r
CP001593_1 407 ----------QELAKVMIKEVDRLNRAVTELLGLVRPSDL 436

CP001593_3251: domain 1 of 1, from 136 to 196: score 46.9, E = 5.4e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ + f+a+++HELRTPL++Ir+++el+++ + e +
CP001593_3 136 QERLFTADAAHELRTPLAGIRLHLELMEK---------QGIAESK-- 171

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++++ ++ l + i++lL lsr++++
CP001593_3 172 ---------------SLINRIDLLMHTIEQLLMLSRAGQN 196

CP001593_2199: domain 1 of 1, from 497 to 559: score 40.4, E = 3.6e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a ++++ +l+H++++ L++I+g +el + + s+ +r
CP001593_2 497 AVGQLTGGLAHDFNNLLAVIIGSLELTAT----------DSSDATR- 532

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++++l++aer +L ++lL +sr ++
CP001593_2 533 -------------IHRALKAAERGAQLTQRLLAFSRKQSL 559

CP001593_1563: domain 1 of 1, from 195 to 255: score 36.2, E = 5.5e-10
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+k ++ +++HELRTPL +r + + + l+e ++
CP001593_1 195 SKKLLIDGIAHELRTPLVRLRYRLAMSDN-----------LTESEQ- 229

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +++++ +l++Li++lL+++r++ +
CP001593_1 230 --------------QALHHDIGQLEALIDELLTYARLDRP 255


Histogram of all scores:
score obs exp (one = represents 12 sequences)
----- --- ---
-14 1 0|=
-13 14 2|*=
-12 120 80|======*===
-11 271 419|======================= *
-10 599 778|================================================== *
-9 652 804|======================================================= *
-8 677 602|==================================================*======
-7 498 379|===============================*==========
-6 290 218|==================*======
-5 183 119|=========*======
-4 96 64|=====*==
-3 52 33|==*==
-2 25 17|=*=
-1 23 9|*=
0 5 4|*
1 5 2|*
2 3 1|*
3 1 0|=
4 3 0|=
5 0 0|
6 2 0|=
> 7 22 -|==


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 293.7669
P(chi-square) = 0

Total sequences searched: 3542

Whole sequence top hits:
tophits_s report:
Total hits: 19
Satisfying E cutoff: 19
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 19
Satisfying E cutoff: 19
Total memory: 28K


Acknowledgements:

This research is funded by:

Developed by: