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Chlamydiae/Verrucomicrobia Chloroflexi Cyanobacteria
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Firmicutes Fusobacteria Gammaproteobacteria
Other Bacteria Planctomycetes Spirochaetes
Thermotogae
Classification of phyla is from NCBI page
Search:
264 projects found  

1 accessions found for Escherichia coli DH1  

Data for CP001637  

Available Atlases
Other Plots
hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: CP001637.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
CP001637_0884 CDS_968706-965950 100.1 5e-28 1
CP001637_3134 CDS_3453066-3451771 90.3 3.1e-25 1
CP001637_1260 CDS_1392598-1389005 81.6 8.9e-23 1
CP001637_2582 CDS_2824986-2827685 80.7 1.6e-22 1
CP001637_1409 CDS_1557096-1559945 80.6 1.8e-22 1
CP001637_0484 CDS_530739-533075 78.9 5.3e-22 1
CP001637_1408 CDS_1556929-1555103 76.4 2.7e-21 1
CP001637_1085 CDS_1192709-1194091 75.4 5.2e-21 1
CP001637_1542 CDS_1715180-1713777 69.8 2e-19 1
CP001637_3972 CDS_4409495-4410868 66.6 1.6e-18 1
CP001637_3510 CDS_3876333-3874909 62.4 2.4e-17 1
CP001637_3889 CDS_4312544-4311147 61.5 4.5e-17 1
CP001637_2986 CDS_3286349-3287791 61.0 6.2e-17 1
CP001637_0659 CDS_713279-711930 60.7 7.8e-17 1
CP001637_4016 CDS_4458131-4459180 59.7 1.5e-16 1
CP001637_2871 CDS_3156705-3159389 59.6 1.5e-16 1
CP001637_0298 CDS_347896-349248 55.0 3.1e-15 1
CP001637_1644 CDS_1839903-1841261 52.3 1.7e-14 1
CP001637_3780 CDS_4181300-4182400 45.0 2.1e-12 1
CP001637_1990 CDS_2195596-2194295 42.4 1.2e-11 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CP001637_0884 1/1 292 357 .. 1 87 [] 100.1 5e-28
CP001637_3134 1/1 203 269 .. 1 87 [] 90.3 3.1e-25
CP001637_1260 1/1 711 777 .. 1 87 [] 81.6 8.9e-23
CP001637_2582 1/1 428 493 .. 1 87 [] 80.7 1.6e-22
CP001637_1409 1/1 469 534 .. 1 87 [] 80.6 1.8e-22
CP001637_0484 1/1 282 347 .. 1 87 [] 78.9 5.3e-22
CP001637_1408 1/1 388 453 .. 1 87 [] 76.4 2.7e-21
CP001637_1085 1/1 234 302 .. 1 87 [] 75.4 5.2e-21
CP001637_1542 1/1 240 304 .. 1 87 [] 69.8 2e-19
CP001637_3972 1/1 238 300 .. 1 87 [] 66.6 1.6e-18
CP001637_3510 1/1 255 320 .. 1 87 [] 62.4 2.4e-17
CP001637_3889 1/1 244 310 .. 1 87 [] 61.5 4.5e-17
CP001637_2986 1/1 261 327 .. 1 87 [] 61.0 6.2e-17
CP001637_0659 1/1 236 302 .. 1 87 [] 60.7 7.8e-17
CP001637_4016 1/1 129 186 .. 1 79 [. 59.7 1.5e-16
CP001637_2871 1/1 663 730 .. 1 87 [] 59.6 1.5e-16
CP001637_0298 1/1 233 293 .. 1 87 [] 55.0 3.1e-15
CP001637_1644 1/1 235 301 .. 1 87 [] 52.3 1.7e-14
CP001637_3780 1/1 145 205 .. 1 87 [] 45.0 2.1e-12
CP001637_1990 1/1 211 271 .. 1 87 [] 42.4 1.2e-11

Alignments of top-scoring domains:
CP001637_0884: domain 1 of 1, from 292 to 357: score 100.1, E = 5e-28
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
kseflan+sHELRTPL++++g++ l l+ tel++ q
CP001637_0 292 IKSEFLANMSHELRTPLNGVIGFTRLTLK---------TELTPTQ-- 327

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+ l+ti+r+a+ ll++ind+Ld+s++eag
CP001637_0 328 ----------RDHLNTIERSANNLLAIINDVLDFSKLEAG 357

CP001637_3134: domain 1 of 1, from 203 to 269: score 90.3, E = 3.1e-25
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++ f+an+sHELRTPLt+++gy+e++ e ++l r
CP001637_3 203 ARRNFFANVSHELRTPLTVLQGYLEMMNE---------QPLEGAVR- 239

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l+t++++++r++ L+ +lL+ls+iea
CP001637_3 240 ----------EKALHTMREQTQRMEGLVKQLLTLSKIEAA 269

CP001637_1260: domain 1 of 1, from 711 to 777: score 81.6, E = 8.9e-23
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks+fla++sHE+RTP+++I+g++elL + ls eqr
CP001637_1 711 AKSQFLATMSHEIRTPISSIMGFLELLSG---------SGLSKEQR- 747

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e+++ ++ +++ll Li ++Ld +ie+g
CP001637_1 748 ----------VEAISLAYATGQSLLGLIGEILDVDKIESG 777

CP001637_2582: domain 1 of 1, from 428 to 493: score 80.7, E = 1.6e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks fla++sHE+RTPL +I+g+a+lL + ++ q
CP001637_2 428 AKSAFLAAMSHEIRTPLYGILGTAQLLAD---------NPALNAQ-- 463

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+ l+ i +++e+ll ++nd+Ld+s ieag
CP001637_2 464 ----------RDDLRAITDSGESLLTILNDILDYSAIEAG 493

CP001637_1409: domain 1 of 1, from 469 to 534: score 80.6, E = 1.8e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ks fla++sHELRTPL +I+g+++lL++ el+
CP001637_1 469 SKSMFLATVSHELRTPLYGIIGNLDLLQT---------KELPKGV-- 504

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ + +++ ll++i+d+Ld+s+ie++
CP001637_1 505 ----------DRLVTAMNNSSSLLLKIISDILDFSKIESE 534

CP001637_0484: domain 1 of 1, from 282 to 347: score 78.9, E = 5.3e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k+ f++++sHELRTPL++I g++ +Ll+ tel++eq
CP001637_0 282 DKTTFISTISHELRTPLNGIVGLSRILLD---------TELTAEQ-- 317

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++yl+ti+ +a l ++ nd+ d+ ++e
CP001637_0 318 ----------EKYLKTIHVSAVTLGNIFNDIIDMDKMERR 347

CP001637_1408: domain 1 of 1, from 388 to 453: score 76.4, E = 2.7e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++e++a+++HE R+PLtaIrgy+++L+ ++ ++ +
CP001637_1 388 TLGELMAGVAHEVRNPLTAIRGYVQILRQ---------QTSDPIH-- 423

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+eyl+++l+e++++++ i++lL++sr ++
CP001637_1 424 ----------QEYLSVVLKEIDSINKVIQQLLEFSRPRHS 453

CP001637_1085: domain 1 of 1, from 234 to 302: score 75.4, E = 5.2e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +fl++lsHEL+TPL+++r +elL +++ ++l++eq
CP001637_1 234 QRHQFLRHLSHELKTPLASMREGTELLADQV------VGPLTPEQ-- 272

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e +++++++++ l++Li++lLd+ r +a
CP001637_1 273 ----------KEVVSILDSSSRNLQKLIEQLLDYNRKQAD 302

CP001637_1542: domain 1 of 1, from 240 to 304: score 69.8, E = 2e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+a++sHELRTPL+++rg +e++++++ + ++e+
CP001637_1 240 MRRDFMADISHELRTPLAVLRGELEAIQDGV-------RKFTPET-- 277

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +++ e+ l +L++dl +ls ++g
CP001637_1 278 -------------VASLQAEVGTLTKLVDDLHQLSMSDEG 304

CP001637_3972: domain 1 of 1, from 238 to 300: score 66.6, E = 1.6e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++++l+++sHELRTPLt +++ + lL++ +++
CP001637_3 238 SQQRLLSDISHELRTPLTRLQLGTALLRR---------RSGESKE-- 273

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
le+i+ ea+rl+++indlL +sr ++
CP001637_3 274 -------------LERIETEAQRLDSMINDLLVMSRNQQK 300

CP001637_3510: domain 1 of 1, from 255 to 320: score 62.4, E = 2.4e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ + +l HEL+ PL+aIrg+ae+L+e ++ +e
CP001637_3 255 YIEQYVYALTHELKSPLAAIRGAAEILRE---------GPPPEVV-- 290

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++++ il + r+++L++ lL +r+e+
CP001637_3 291 ----------ARFTDNILTQNARMQALVETLLRQARLENR 320

CP001637_3889: domain 1 of 1, from 244 to 310: score 61.5, E = 4.5e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++ ++a+++HE+R+PL++I+g+a+ e +++++ e
CP001637_3 244 ALGHLAAGVAHEIRNPLSSIKGLAKYFAE--------RAPAGGEA-- 280

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ +++ +ea+rl+r +++lL+l + +
CP001637_3 281 ----------HQLAQVMAKEADRLNRVVSELLELVKPTHL 310

CP001637_2986: domain 1 of 1, from 261 to 327: score 61.0, E = 6.2e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++s f a+++HE+RTP+t +++ +e++l + +s +++
CP001637_2 261 RQSNFSADIAHEIRTPITNLITQTEIALS---------QSRSQKEL- 297

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ l + l+e+ r+ ++++d+L l++++++
CP001637_2 298 ----------EDVLYSNLEELTRMAKMVSDMLFLAQADNN 327

CP001637_0659: domain 1 of 1, from 236 to 302: score 60.7, E = 7.8e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++f+++++HELR PLta++ +e+++ ++ +++ r
CP001637_0 236 RERRFTSDAAHELRSPLTALKVQTEVAQL---------SDDDPQAR- 272

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l +++ ++r rL+++lL+lsr+++
CP001637_0 273 ----------KKALLQLHSGIDRATRLVDQLLTLSRLDSL 302

CP001637_4016: domain 1 of 1, from 129 to 186: score 59.7, E = 1.5e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a ++++++l+HE+++PL ++rg+a+lL + +l+++ +
CP001637_4 129 AARDLVRGLAHEIKNPLGGLRGAAQLLSK----------ALPDPSL- 164

peLRledpeyreyletilreaerllrLindlL<-*
ey+++i+++a+rl++L+++lL
CP001637_4 165 ----------LEYTKVIIEQADRLRNLVDRLL 186

CP001637_2871: domain 1 of 1, from 663 to 730: score 59.6, E = 1.5e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +la+lsH+LRTPLt++ g ae+L +l + ++++
CP001637_2 663 IRNALLAALSHDLRTPLTVLFGQAEILTLDL-------ASEGSPH-- 700

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ + i++ + rL+n+lLd++ri++g
CP001637_2 701 ----------ARQASEIRQHVLNTTRLVNNLLDMARIQSG 730

CP001637_0298: domain 1 of 1, from 233 to 293: score 55.0, E = 3.1e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ ++a++sH+LRTPLt Ir+++e++ e ++
CP001637_0 233 DRTLLMAGVSHDLRTPLTRIRLATEMMSE---------QD------- 263

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ e+i +++e ++++i+++ d+ r +++
CP001637_0 264 ----------GYLAESINKDIEECNAIIEQFIDYLRTGQE 293

CP001637_1644: domain 1 of 1, from 235 to 301: score 52.3, E = 1.7e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++s+f+ +l+HELRTP++a++g ++ l +++s +
CP001637_1 235 RLSQFADDLAHELRTPINALLGQNQVTLS---------QTRSIAE-- 270

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
y++ + ++e+e ++rL +++L l+r++ +
CP001637_1 271 ---------YQKTIAGNIEELENISRLTENILFLARADKN 301

CP001637_3780: domain 1 of 1, from 145 to 205: score 45.0, E = 2.1e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ f+a+++HELRTPL+++r+++elL + t+
CP001637_3 145 NERLFTADVAHELRTPLAGVRLHLELLAK---------TH------- 175

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + + ++++ + +++lL+l+r+++
CP001637_3 176 ----------HIDVAPLVARLDQMMESVSQLLQLARAGQS 205

CP001637_1990: domain 1 of 1, from 211 to 271: score 42.4, E = 1.2e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+k +++ +++HELRTPL +r +e+ + ls+ +
CP001637_1 211 SKKQLIDGIAHELRTPLVRLRYRLEMSDN-----------LSAAE-- 244

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + r++ +l++Li++lL+++r++ +
CP001637_1 245 -------------SQALNRDISQLEALIEELLTYARLDRP 271


Histogram of all scores:
score obs exp (one = represents 13 sequences)
----- --- ---
-14 13 0|=
-13 50 3|*===
-12 193 95|=======*=======
-11 415 493|================================ *
-10 719 914|======================================================== *
-9 765 944|==========================================================*
-8 709 707|======================================================*
-7 495 445|==================================*====
-6 342 256|===================*=======
-5 187 140|==========*====
-4 93 75|=====*==
-3 56 39|==*==
-2 29 20|=*=
-1 35 10|*==
0 16 5|*=
1 7 2|*
2 12 1|*
3 2 0|=
4 0 0|
> 5 22 -|==


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 324.2374
P(chi-square) = 0

Total sequences searched: 4160

Whole sequence top hits:
tophits_s report:
Total hits: 20
Satisfying E cutoff: 20
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 20
Satisfying E cutoff: 20
Total memory: 28K


Acknowledgements:

This research is funded by:

Developed by: