Acidobacteria Actinobacteria Alphaproteobacteria
Aquificae Bacteroidetes/Chlorobi Betaproteobacteria
Chlamydiae/Verrucomicrobia Chloroflexi Cyanobacteria
Deinococcus-Thermus Deltaproteobacteria Epsilonproteobacteria
Firmicutes Fusobacteria Gammaproteobacteria
Other Bacteria Planctomycetes Spirochaetes
Thermotogae
Classification of phyla is from NCBI page
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5 accessions found for   

Data for CP001645  

Available Atlases
Other Plots
hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
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HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: CP001645.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
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Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
CP001645_0829 CDS_925294-923399 67.2 3e-19 1
CP001645_0839 CDS_935938-937494 64.4 1.9e-18 1
CP001645_0454 CDS_498727-501153 62.0 9.1e-18 1
CP001645_0320 CDS_352294-350978 60.5 2.4e-17 1
CP001645_0422 CDS_461638-459254 60.4 2.5e-17 1
CP001645_0817 CDS_908102-909388 54.7 1e-15 1
CP001645_0145 CDS_167394-165898 35.5 2.9e-10 1
CP001645_0434 CDS_474505-476352 30.2 9.3e-09 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CP001645_0829 1/1 251 317 .. 1 87 [] 67.2 3e-19
CP001645_0839 1/1 281 345 .. 1 87 [] 64.4 1.9e-18
CP001645_0454 1/1 315 380 .. 1 87 [] 62.0 9.1e-18
CP001645_0320 1/1 215 280 .. 1 87 [] 60.5 2.4e-17
CP001645_0422 1/1 415 482 .. 1 87 [] 60.4 2.5e-17
CP001645_0817 1/1 217 275 .. 1 87 [] 54.7 1e-15
CP001645_0145 1/1 244 309 .. 1 87 [] 35.5 2.9e-10
CP001645_0434 1/1 387 455 .. 1 87 [] 30.2 9.3e-09

Alignments of top-scoring domains:
CP001645_0829: domain 1 of 1, from 251 to 317: score 67.2, E = 3e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k++fla++sHELRTPL+a++g a+lL ++++ +e
CP001645_0 251 LKDDFLATVSHELRTPLNAVLGWAQLLNMRAY----------DEA-- 285

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++++ +e i+r+a+ +Li+dlLd+s i +g
CP001645_0 286 --------MFKRGIEAIERSARTQVHLIDDLLDMSAILSG 317

CP001645_0839: domain 1 of 1, from 281 to 345: score 64.4, E = 1.9e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++++a++sHELRTPL+++rg +e+L++++ +l++
CP001645_0 281 MRRQLTADISHELRTPLAVLRGELEALEDGV-------RPLTATS-- 318

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
l +++ e+ l++Li+dl +ls ++ g
CP001645_0 319 -------------LASLQAEVSTLSKLIDDLYELSLADVG 345

CP001645_0454: domain 1 of 1, from 315 to 380: score 62.0, E = 9.1e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k f+a +sHE+RTP+++I+ +elL++ + l+ +q
CP001645_0 315 DKAMFVAFISHEIRTPMHTILSSLELLQR---------SQLNGQQ-- 350

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +++++e ll+L++d+L++sr+e+
CP001645_0 351 ----------ASRAVAAISASETLLALLDDVLEYSRLESR 380

CP001645_0320: domain 1 of 1, from 215 to 280: score 60.5, E = 2.4e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ f+a+++H LRTPL+a+++ ++++ + ++see+r
CP001645_0 215 HQRAFVADAAHALRTPLAALKLQLQVADR----------AQSEEER- 250

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r + ++r +er+ rL+ +lL+l+r e g
CP001645_0 251 ----------RAAHADLHRGVERMIRLVGQLLTLARQEPG 280

CP001645_0422: domain 1 of 1, from 415 to 482: score 60.4, E = 2.5e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+++fla +sHELR PL++I+ + +L+++l ++ s+
CP001645_0 415 ARDQFLAVVSHELRSPLNGIQNWTYVLENQL-------SDGSPLV-- 452

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l i+ +e+ rLi+dlLd +r +g
CP001645_0 453 ----------QRALAGIKTGVEQQVRLIEDLLDATRVMSG 482

CP001645_0817: domain 1 of 1, from 217 to 275: score 54.7, E = 1e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++ +la+++H+L+TPL+ +r+ ae+L +
CP001645_0 217 ERNTMLAGIAHDLKTPLSRLRLRAEMLAD------------------ 245

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ i+r++e+++++++++L +++ +
CP001645_0 246 ----------QKAGAGIERDVESMSAIVEQFLAYAQSGDS 275

CP001645_0145: domain 1 of 1, from 244 to 309: score 35.5, E = 2.9e-10
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a ++f+a+++HELRTPL+aI++ a + se++r
CP001645_0 244 ADRRFFADAAHELRTPLAAIQAQAYVVSH----------SDSEDDR- 279

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+l+ +r + r + + lL ++r++a
CP001645_0 280 ----------STALREFDRGISRATQSLAKLLAIARLDAR 309

CP001645_0434: domain 1 of 1, from 387 to 455: score 30.2, E = 9.3e-09
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++++a++ HEL++PLta+ ++++ + la+++ +e
CP001645_0 387 VLGQMAAGITHELNQPLTALTTLSDNANQ-----LAERGRIDEVR-- 426

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
l i + a+r+ r+++ + +sr +
CP001645_0 427 -----------GNLTHISQLANRMGRIVSHIKAFSRKGDA 455


Histogram of all scores:
score obs exp (one = represents 4 sequences)
----- --- ---
-15 3 0|=
-14 9 0|===
-13 9 0|===
-12 37 26|======*===
-11 117 139|============================== *
-10 188 259|=============================================== *
-9 219 267|======================================================= *
-8 228 200|=================================================*=======
-7 152 126|===============================*======
-6 84 72|=================*===
-5 59 39|=========*=====
-4 29 21|=====*==
-3 22 11|==*===
-2 7 5|=*
-1 5 3|*=
0 0 1|*
1 1 0|=
2 1 0|=
3 0 0|
> 4 10 -|===


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 68.9737
P(chi-square) = 6.994e-11

Total sequences searched: 1180

Whole sequence top hits:
tophits_s report:
Total hits: 8
Satisfying E cutoff: 8
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 8
Satisfying E cutoff: 8
Total memory: 24K


Acknowledgements:

This research is funded by:

Developed by: