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Thermotogae
Classification of phyla is from NCBI page
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106 projects found  

1 accessions found for Mycobacterium tuberculosis KZN 1435  

Data for CP001658  

Available Atlases
Other Plots
hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: CP001658.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
CP001658_3896 CDS_4198048-4196528 83.7 2.2e-23 1
CP001658_3372 CDS_3624733-3623030 74.9 7e-21 1
CP001658_0789 CDS_853594-855051 73.5 1.7e-20 1
CP001658_0503 CDS_579552-580784 72.4 3.6e-20 1
CP001658_3027 CDS_3260281-3262863 65.2 3.9e-18 1
CP001658_3075 CDS_3314459-3312945 60.6 7.8e-17 1
CP001658_3159 CDS_3406137-3407477 54.0 5.8e-15 1
CP001658_3022 CDS_3254888-3255541 43.3 6.1e-12 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CP001658_3896 1/1 277 343 .. 1 87 [] 83.7 2.2e-23
CP001658_3372 1/1 295 362 .. 1 87 [] 74.9 7e-21
CP001658_0789 1/1 249 313 .. 1 87 [] 73.5 1.7e-20
CP001658_0503 1/1 157 223 .. 1 87 [] 72.4 3.6e-20
CP001658_3027 1/1 632 700 .. 1 87 [] 65.2 3.9e-18
CP001658_3075 1/1 239 311 .. 1 87 [] 60.6 7.8e-17
CP001658_3159 1/1 230 296 .. 1 87 [] 54.0 5.8e-15
CP001658_3022 1/1 1 52 [. 17 87 .] 43.3 6.1e-12

Alignments of top-scoring domains:
CP001658_3896: domain 1 of 1, from 277 to 343: score 83.7, E = 2.2e-23
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++f+a++sHELRTPL+aIrgy+el ++ ++e +
CP001658_3 277 RVRQFVADASHELRTPLAAIRGYTELTQR---------IGDDPEAV- 313

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + +++ +e+er+ rL++dlL l+r+++g
CP001658_3 314 ----------AHAMSRVASETERITRLVEDLLLLARLDSG 343

CP001658_3372: domain 1 of 1, from 295 to 362: score 74.9, E = 7e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++f++++sHELRTPLt++r++a+l+ + ++++l++
CP001658_3 295 LQRRFTSDVSHELRTPLTTVRMAADLIYD-------HSADLDPTL-- 332

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+ +e + +e++r + L+ndlL++sr +ag
CP001658_3 333 ----------RRSTELMVSELDRFETLLNDLLEISRHDAG 362

CP001658_0789: domain 1 of 1, from 249 to 313: score 73.5, E = 1.7e-20
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+ ++sHELRTPLt+Irg+ael + ++ + ++
CP001658_0 249 RMRQFITDASHELRTPLTTIRGFAELYRQGA-----------ARDV- 283

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+l++i++ea r+ L++dlL l+r++a
CP001658_0 284 ----------GMLLSRIESEASRMGLLVDDLLLLARLDAH 313

CP001658_0503: domain 1 of 1, from 157 to 223: score 72.4, E = 3.6e-20
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+++f+an+sHEL+TP+ a+ ++ae+Ll+ ++ ++e++
CP001658_0 157 ARRDFVANVSHELKTPVGAMALLAEALLA---------SADDSETV- 193

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r++ e++l ea+rl +++ +l +lsr++
CP001658_0 194 ----------RRFAEKVLIEANRLGDMVAELIELSRLQGA 223

CP001658_3027: domain 1 of 1, from 632 to 700: score 65.2, E = 3.9e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +l+++sH+LRTPL+a + +++ L++ +d + s+e++
CP001658_3 632 LRRSLLSAVSHDLRTPLAAAKVAVSSLRT-------EDVAFSPEDT- 670

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e+l ti++++++l +L+ +lLd sr+ ag
CP001658_3 671 ----------AELLATIEESIDQLTALVANLLDSSRLAAG 700

CP001658_3075: domain 1 of 1, from 239 to 311: score 60.6, E = 7.8e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +++ ++ HELRTPLt++r+++elL + + ++g + l+ +++
CP001658_3 239 RQARLVTDAGHELRTPLTSLRTNVELLMASM---APGAPRLPKQEM- 281

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ +l ++e l+ L+ dl dlsr +ag
CP001658_3 282 ----------VDLRADVLAQIEELSTLVGDLVDLSRGDAG 311

CP001658_3159: domain 1 of 1, from 230 to 296: score 54.0, E = 5.8e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++f+a sHELRTPLta+r+++e+L + +l+++qr
CP001658_3 230 SARDFAAVSSHELRTPLTAMRTNLEVLST---------LDLPDDQR- 266

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e l+ ++r r+++ ++ l l++ e
CP001658_3 267 ----------KEVLNDVIRTQSRIEATLSALERLAQGELS 296

CP001658_3022: domain 1 of 1, from 1 to 52: score 43.3, E = 6.1e-12
*->LtaIrgyaelLleeldkvlagdtelseeqrlpeLRledpeyreylet
++aI+gyael + ++ ++l++ + + +l +
CP001658_3 1 MAAIQGYAELTRQDS-------SDLPPTT------------EYALAR 28

ilreaerllrLindlLdlsrieag<-*
i++ea+r+ L+++lL lsr+ +g
CP001658_3 29 IESEARRMTLLVDELLLLSRLSEG 52


Histogram of all scores:
score obs exp (one = represents 14 sequences)
----- --- ---
-15 1 0|=
-14 6 0|=
-13 49 3|*===
-12 189 92|======*=======
-11 391 481|============================ *
-10 726 892|==================================================== *
-9 825 922|==========================================================*
-8 682 690|=================================================*
-7 490 435|===============================*===
-6 291 250|=================*===
-5 176 137|=========*===
-4 107 73|=====*==
-3 60 38|==*==
-2 30 20|=*=
-1 9 10|*
0 8 5|*
1 2 2|*
2 3 1|*
3 2 0|=
4 1 0|=
5 0 0|
> 6 12 -|=


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 215.2594
P(chi-square) = 4.316e-309

Total sequences searched: 4060

Whole sequence top hits:
tophits_s report:
Total hits: 8
Satisfying E cutoff: 8
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 8
Satisfying E cutoff: 8
Total memory: 24K


Acknowledgements:

This research is funded by:

Developed by: