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Other Bacteria Planctomycetes Spirochaetes
Thermotogae
Classification of phyla is from NCBI page
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264 projects found  

1 accessions found for Escherichia coli BL21(DE3)  

Data for CP001665  

Available Atlases
Other Plots
hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: CP001665.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
CP001665_0928 CDS_992258-989502 100.1 5.1e-28 1
CP001665_3180 CDS_3399093-3397798 91.0 2e-25 1
CP001665_1286 CDS_1377642-1374049 81.6 9.1e-23 1
CP001665_2542 CDS_2721964-2724663 80.7 1.6e-22 1
CP001665_1423 CDS_1529571-1532420 80.6 1.8e-22 1
CP001665_0521 CDS_552279-554615 78.9 5.4e-22 1
CP001665_1422 CDS_1529404-1527578 76.4 2.8e-21 1
CP001665_1113 CDS_1183001-1184428 75.4 5.3e-21 1
CP001665_1553 CDS_1678011-1676608 69.8 2.1e-19 1
CP001665_4014 CDS_4329575-4330948 66.6 1.6e-18 1
CP001665_3536 CDS_3788678-3787254 62.4 2.5e-17 1
CP001665_3932 CDS_4232501-4231125 62.1 3e-17 1
CP001665_3017 CDS_3228932-3230380 61.0 6.3e-17 1
CP001665_0701 CDS_735883-734534 60.7 7.9e-17 1
CP001665_4060 CDS_4379435-4380484 59.7 1.5e-16 1
CP001665_2896 CDS_3098097-3100781 59.6 1.5e-16 1
CP001665_0332 CDS_377555-378907 55.0 3.1e-15 1
CP001665_1651 CDS_1799185-1800543 52.3 1.8e-14 1
CP001665_3824 CDS_4102113-4103213 45.0 2.2e-12 1
CP001665_2000 CDS_2154304-2153003 42.4 1.2e-11 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CP001665_0928 1/1 292 357 .. 1 87 [] 100.1 5.1e-28
CP001665_3180 1/1 203 269 .. 1 87 [] 91.0 2e-25
CP001665_1286 1/1 711 777 .. 1 87 [] 81.6 9.1e-23
CP001665_2542 1/1 428 493 .. 1 87 [] 80.7 1.6e-22
CP001665_1423 1/1 469 534 .. 1 87 [] 80.6 1.8e-22
CP001665_0521 1/1 282 347 .. 1 87 [] 78.9 5.4e-22
CP001665_1422 1/1 388 453 .. 1 87 [] 76.4 2.8e-21
CP001665_1113 1/1 249 317 .. 1 87 [] 75.4 5.3e-21
CP001665_1553 1/1 240 304 .. 1 87 [] 69.8 2.1e-19
CP001665_4014 1/1 238 300 .. 1 87 [] 66.6 1.6e-18
CP001665_3536 1/1 255 320 .. 1 87 [] 62.4 2.5e-17
CP001665_3932 1/1 237 303 .. 1 87 [] 62.1 3e-17
CP001665_3017 1/1 261 327 .. 1 87 [] 61.0 6.3e-17
CP001665_0701 1/1 236 302 .. 1 87 [] 60.7 7.9e-17
CP001665_4060 1/1 129 186 .. 1 79 [. 59.7 1.5e-16
CP001665_2896 1/1 663 730 .. 1 87 [] 59.6 1.5e-16
CP001665_0332 1/1 233 293 .. 1 87 [] 55.0 3.1e-15
CP001665_1651 1/1 235 301 .. 1 87 [] 52.3 1.8e-14
CP001665_3824 1/1 145 205 .. 1 87 [] 45.0 2.2e-12
CP001665_2000 1/1 211 271 .. 1 87 [] 42.4 1.2e-11

Alignments of top-scoring domains:
CP001665_0928: domain 1 of 1, from 292 to 357: score 100.1, E = 5.1e-28
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
kseflan+sHELRTPL++++g++ l l+ tel++ q
CP001665_0 292 IKSEFLANMSHELRTPLNGVIGFTRLTLK---------TELTPTQ-- 327

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+ l+ti+r+a+ ll++ind+Ld+s++eag
CP001665_0 328 ----------RDHLNTIERSANNLLAIINDVLDFSKLEAG 357

CP001665_3180: domain 1 of 1, from 203 to 269: score 91.0, E = 2e-25
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++ f+an+sHELRTPLt+++gy+e++ e ++l r
CP001665_3 203 ARRNFFANVSHELRTPLTVLQGYLEMMDE---------QPLEGAVR- 239

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l+t++++++r++ L+ +lL+ls+iea
CP001665_3 240 ----------EKALHTMREQTQRMEGLVKQLLTLSKIEAA 269

CP001665_1286: domain 1 of 1, from 711 to 777: score 81.6, E = 9.1e-23
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks+fla++sHE+RTP+++I+g++elL + ls eqr
CP001665_1 711 AKSQFLATMSHEIRTPISSIMGFLELLSG---------SGLSKEQR- 747

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e+++ ++ +++ll Li ++Ld +ie+g
CP001665_1 748 ----------VEAISLAYATGQSLLGLIGEILDVDKIESG 777

CP001665_2542: domain 1 of 1, from 428 to 493: score 80.7, E = 1.6e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks fla++sHE+RTPL +I+g+a+lL + ++ q
CP001665_2 428 AKSAFLAAMSHEIRTPLYGILGTAQLLAD---------NPALNAQ-- 463

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+ l+ i +++e+ll ++nd+Ld+s ieag
CP001665_2 464 ----------RDDLRAITDSGESLLTILNDILDYSAIEAG 493

CP001665_1423: domain 1 of 1, from 469 to 534: score 80.6, E = 1.8e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ks fla++sHELRTPL +I+g+++lL++ el+
CP001665_1 469 SKSMFLATVSHELRTPLYGIIGNLDLLQT---------KELPKGV-- 504

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ + +++ ll++i+d+Ld+s+ie++
CP001665_1 505 ----------DRLVTAMNNSSSLLLKIISDILDFSKIESE 534

CP001665_0521: domain 1 of 1, from 282 to 347: score 78.9, E = 5.4e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k+ f++++sHELRTPL++I g++ +Ll+ tel++eq
CP001665_0 282 DKTTFISTISHELRTPLNGIVGLSRILLD---------TELTAEQ-- 317

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++yl+ti+ +a l ++ nd+ d+ ++e
CP001665_0 318 ----------EKYLKTIHVSAVTLGNIFNDIIDMDKMERR 347

CP001665_1422: domain 1 of 1, from 388 to 453: score 76.4, E = 2.8e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++e++a+++HE R+PLtaIrgy+++L+ ++ ++ +
CP001665_1 388 TLGELMAGVAHEVRNPLTAIRGYVQILRQ---------QTSDPIH-- 423

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+eyl+++l+e++++++ i++lL++sr ++
CP001665_1 424 ----------QEYLSVVLKEIDSINKVIQQLLEFSRPRHS 453

CP001665_1113: domain 1 of 1, from 249 to 317: score 75.4, E = 5.3e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +fl++lsHEL+TPL+++r +elL +++ ++l++eq
CP001665_1 249 QRHQFLRHLSHELKTPLASMREGTELLADQV------VGPLTPEQ-- 287

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e +++++++++ l++Li++lLd+ r +a
CP001665_1 288 ----------KEVVSILDSSSRNLQKLIEQLLDYNRKQAD 317

CP001665_1553: domain 1 of 1, from 240 to 304: score 69.8, E = 2.1e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+a++sHELRTPL+++rg +e++++++ + ++e+
CP001665_1 240 MRRDFMADISHELRTPLAVLRGELEAIQDGV-------RKFTPET-- 277

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +++ e+ l +L++dl +ls ++g
CP001665_1 278 -------------VASLQAEVGTLTKLVDDLHQLSMSDEG 304

CP001665_4014: domain 1 of 1, from 238 to 300: score 66.6, E = 1.6e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++++l+++sHELRTPLt +++ + lL++ +++
CP001665_4 238 SQQRLLSDISHELRTPLTRLQLGTALLRR---------RSGESKE-- 273

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
le+i+ ea+rl+++indlL +sr ++
CP001665_4 274 -------------LERIETEAQRLDSMINDLLVMSRNQQK 300

CP001665_3536: domain 1 of 1, from 255 to 320: score 62.4, E = 2.5e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ + +l HEL+ PL+aIrg+ae+L+e ++ +e
CP001665_3 255 YIEQYVYALTHELKSPLAAIRGAAEILRE---------GPPPEVV-- 290

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++++ il + r+++L++ lL +r+e+
CP001665_3 291 ----------ARFTDNILTQNARMQALVETLLRQARLENR 320

CP001665_3932: domain 1 of 1, from 237 to 303: score 62.1, E = 3e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++ ++a+++HE+R+PL++I+g+a+ e +++++ e
CP001665_3 237 ALGHLAAGVAHEIRNPLSSIKGLAKYFAE--------RAPAGGEA-- 273

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ +++ +ea+rl+r +++lL+l r +
CP001665_3 274 ----------HQLAQVMAKEADRLNRVVSELLELVRPTHL 303

CP001665_3017: domain 1 of 1, from 261 to 327: score 61.0, E = 6.3e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++s f a+++HE+RTP+t +++ +e++l + +s +++
CP001665_3 261 RQSNFSADIAHEIRTPITNLITQTEIALS---------QSRSQKEL- 297

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ l + l+e+ r+ ++++d+L l++++++
CP001665_3 298 ----------EDVLYSNLEELTRMAKMVSDMLFLAQADNN 327

CP001665_0701: domain 1 of 1, from 236 to 302: score 60.7, E = 7.9e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++f+++++HELR PLta++ +e+++ ++ +++ r
CP001665_0 236 RERRFTSDAAHELRSPLTALKVQTEVAQL---------SDDDPQAR- 272

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l +++ ++r rL+++lL+lsr+++
CP001665_0 273 ----------KKALLQLHSGIDRATRLVDQLLTLSRLDSL 302

CP001665_4060: domain 1 of 1, from 129 to 186: score 59.7, E = 1.5e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a ++++++l+HE+++PL ++rg+a+lL + +l+++ +
CP001665_4 129 AARDLVRGLAHEIKNPLGGLRGAAQLLSK----------ALPDPSL- 164

peLRledpeyreyletilreaerllrLindlL<-*
ey+++i+++a+rl++L+++lL
CP001665_4 165 ----------LEYTKVIIEQADRLRNLVDRLL 186

CP001665_2896: domain 1 of 1, from 663 to 730: score 59.6, E = 1.5e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +la+lsH+LRTPLt++ g ae+L +l + ++++
CP001665_2 663 IRNALLAALSHDLRTPLTVLFGQAEILTLDL-------ASEGSPH-- 700

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ + i++ + rL+n+lLd++ri++g
CP001665_2 701 ----------ARQASEIRQHVLNTTRLVNNLLDMARIQSG 730

CP001665_0332: domain 1 of 1, from 233 to 293: score 55.0, E = 3.1e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ ++a++sH+LRTPLt Ir+++e++ e ++
CP001665_0 233 DRTLLMAGVSHDLRTPLTRIRLATEMMSE---------QD------- 263

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ e+i +++e ++++i+++ d+ r +++
CP001665_0 264 ----------GYLAESINKDIEECNAIIEQFIDYLRTGQE 293

CP001665_1651: domain 1 of 1, from 235 to 301: score 52.3, E = 1.8e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++s+f+ +l+HELRTP++a++g ++ l +++s +
CP001665_1 235 RLSQFADDLAHELRTPINALLGQNQVTLS---------QTRSIAE-- 270

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
y++ + ++e+e ++rL +++L l+r++ +
CP001665_1 271 ---------YQKTIAGNIEELENISRLTENILFLARADKN 301

CP001665_3824: domain 1 of 1, from 145 to 205: score 45.0, E = 2.2e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ f+a+++HELRTPL+++r+++elL + t+
CP001665_3 145 NERLFTADVAHELRTPLAGVRLHLELLAK---------TH------- 175

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + + ++++ + +++lL+l+r+++
CP001665_3 176 ----------HIDVAPLVARLDQMMESVSQLLQLARAGQS 205

CP001665_2000: domain 1 of 1, from 211 to 271: score 42.4, E = 1.2e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+k +++ +++HELRTPL +r +e+ + ls+ +
CP001665_2 211 SKKQLIDGIAHELRTPLVRLRYRLEMSDN-----------LSAAE-- 244

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + r++ +l++Li++lL+++r++ +
CP001665_2 245 -------------SQALNRDISQLEALIEELLTYARLDRP 271


Histogram of all scores:
score obs exp (one = represents 14 sequences)
----- --- ---
-15 2 0|=
-14 23 0|==
-13 63 3|*====
-12 208 96|======*========
-11 445 501|================================ *
-10 711 929|=================================================== *
-9 793 960|========================================================= *
-8 704 718|===================================================*
-7 514 453|================================*====
-6 313 260|==================*====
-5 191 143|==========*===
-4 88 76|=====*=
-3 59 40|==*==
-2 26 21|=*
-1 34 11|*==
0 15 5|*=
1 7 3|*
2 8 1|*
3 2 0|=
4 0 0|
> 5 22 -|==


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 323.6262
P(chi-square) = 0

Total sequences searched: 4228

Whole sequence top hits:
tophits_s report:
Total hits: 20
Satisfying E cutoff: 20
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 20
Satisfying E cutoff: 20
Total memory: 28K


Acknowledgements:

This research is funded by:

Developed by: