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Classification of phyla is from NCBI page
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106 projects found  

1 accessions found for Thermomonospora curvata DSM 43183  

Data for CP001738  

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hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: CP001738.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
CP001738_2588 CDS_3086884-3090795 89.2 7.2e-25 1
CP001738_2101 CDS_2508236-2509378 77.7 1.3e-21 1
CP001738_4685 CDS_5419427-5415681 76.4 3.2e-21 1
CP001738_4684 CDS_5415601-5411450 75.8 4.6e-21 1
CP001738_0565 CDS_647157-648674 74.6 1e-20 1
CP001738_1430 CDS_1664525-1663539 70.0 2.1e-19 1
CP001738_3962 CDS_4619954-4618170 68.9 4.2e-19 1
CP001738_0093 CDS_96461-98326 63.0 2e-17 1
CP001738_1332 CDS_1545337-1546746 61.9 4e-17 1
CP001738_0683 CDS_780157-781395 61.6 4.9e-17 1
CP001738_4663 CDS_5379468-5378104 59.0 2.8e-16 1
CP001738_4040 CDS_4704412-4703135 54.4 5.2e-15 1
CP001738_1101 CDS_1288043-1286349 51.0 5.1e-14 1
CP001738_1661 CDS_1986914-1988155 50.4 7.3e-14 1
CP001738_0449 CDS_530589-529228 49.9 1e-13 1
CP001738_3291 CDS_3880863-3879526 44.7 3.1e-12 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CP001738_2588 1/1 875 943 .. 1 87 [] 89.2 7.2e-25
CP001738_2101 1/1 151 219 .. 1 87 [] 77.7 1.3e-21
CP001738_4685 1/1 337 404 .. 1 87 [] 76.4 3.2e-21
CP001738_4684 1/1 346 413 .. 1 87 [] 75.8 4.6e-21
CP001738_0565 1/1 265 332 .. 1 87 [] 74.6 1e-20
CP001738_1430 1/1 114 178 .. 1 87 [] 70.0 2.1e-19
CP001738_3962 1/1 263 331 .. 1 87 [] 68.9 4.2e-19
CP001738_0093 1/1 393 461 .. 1 87 [] 63.0 2e-17
CP001738_1332 1/1 241 306 .. 1 87 [] 61.9 4e-17
CP001738_0683 1/1 156 222 .. 1 87 [] 61.6 4.9e-17
CP001738_4663 1/1 233 298 .. 1 87 [] 59.0 2.8e-16
CP001738_4040 1/1 202 268 .. 1 87 [] 54.4 5.2e-15
CP001738_1101 1/1 320 388 .. 1 87 [] 51.0 5.1e-14
CP001738_1661 1/1 192 258 .. 1 87 [] 50.4 7.3e-14
CP001738_0449 1/1 234 299 .. 1 87 [] 49.9 1e-13
CP001738_3291 1/1 223 278 .. 1 77 [. 44.7 3.1e-12

Alignments of top-scoring domains:
CP001738_2588: domain 1 of 1, from 875 to 943: score 89.2, E = 7.2e-25
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
kseflan+sHELRTPL++++ +a+lL e +++l+++q
CP001738_2 875 YKSEFLANMSHELRTPLNSLLVLAKLLSE------NPEGNLTPKQ-- 913

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e+ +ti++++ ll+Lind+Ldls+ eag
CP001738_2 914 ----------VEFAKTIHDSGTDLLQLINDILDLSKVEAG 943

CP001738_2101: domain 1 of 1, from 151 to 219: score 77.7, E = 1.3e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ +++++++HELR PLt+++g++ +Ll+ +++ +++q+
CP001738_2 151 DRADLVSTVAHELRSPLTSVKGFTATLLA-------KWHRFTDDQK- 189

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r +let+ +a+r rLi++lLd srieag
CP001738_2 190 ----------RVMLETVNADADRVTRLISELLDVSRIEAG 219

CP001738_4685: domain 1 of 1, from 337 to 404: score 76.4, E = 3.2e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
ak+ fl+++sHE+RTPLt I+g +e L+++l +++ +
CP001738_4 337 AKTVFLSDISHEFRTPLTLIMGPVEELRARL-------QDAEPWV-- 374

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+ le+i+r + rl++L++ lLd++rieag
CP001738_4 375 ----------RKDLEVIHRNGLRLSKLVDTLLDYARIEAG 404

CP001738_4684: domain 1 of 1, from 346 to 413: score 75.8, E = 4.6e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
ak+ f+ ++sHE+RTPLt I g +e L+ +l ++++
CP001738_4 346 AKTVFFTDISHEFRTPLTLIVGPLEELRSRL-------GPADQWV-- 383

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
re le+i+++a r+ rL++ lLd++rieag
CP001738_4 384 ----------RENLEIIRHSALRMTRLVDTLLDFARIEAG 413

CP001738_0565: domain 1 of 1, from 265 to 332: score 74.6, E = 1e-20
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+a++ HELRTPLtaIrg+ael + ++ ++++ ++
CP001738_0 265 RMRRFIADAGHELRTPLTAIRGFAELYRQGA--------ARDAAEI- 302

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ +i+++a r+ L++dlL l+r++ +
CP001738_0 303 ----------DRLIGRIEDAASRMGLLVEDLLLLARLDRQ 332

CP001738_1430: domain 1 of 1, from 114 to 178: score 70.0, E = 2.1e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++ef+an+sHELRTP++a+ + +e + + + ++
CP001738_1 114 RRREFIANVSHELRTPISALHAQLENIAD---------GITPARP-- 149

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ l+ +l++++rl+rL+ +lLdlsr+++g
CP001738_1 150 -----------QTLRAALEQTQRLERLVAQLLDLSRLDEG 178

CP001738_3962: domain 1 of 1, from 263 to 331: score 68.9, E = 4.2e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++f++++sHELRTPLt+Ir +a++L + +++ s++ +
CP001738_3 263 VQRQFVSDVSHELRTPLTTIRIAADMLYA-------HREQFSDPAV- 301

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ e +++++er ++L+ dlL++sr +ag
CP001738_3 302 ----------GRSAELLQSQLERFEALLADLLEISRHDAG 331

CP001738_0093: domain 1 of 1, from 393 to 461: score 63.0, E = 2e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
ak+ fla++ HELRTP+t+++g+a++L ++++l++ +r
CP001738_0 393 AKDLFLATAGHELRTPITVVQGFASTLVS-------RWDKLGDAER- 431

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r ++eti + a+ l rL++ lL sr+++g
CP001738_0 432 ----------RAAVETIAERARALARLVEHLLLGSRAGTG 461

CP001738_1332: domain 1 of 1, from 241 to 306: score 61.9, E = 4e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+++f+a++sHELR PLta+r+ +e++l + +e+
CP001738_1 241 AQRRFVADVSHELRSPLTALRTQLEVALV----------HPEDED-- 275

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + +l++a+rl++ + d+L+++++eag
CP001738_1 276 ---------WPAVARAALDDADRLQKVVADVLTIAKLEAG 306

CP001738_0683: domain 1 of 1, from 156 to 222: score 61.6, E = 4.9e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++f+an+sHEL+TP+ a++++ae+ + ++ ++e +
CP001738_0 156 IRRDFVANVSHELKTPVGALSLLAETVES---------AADDPEAV- 192

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r++ ++++e+ rl++L++dl++lsr +
CP001738_0 193 ----------RRFSIRMQHESMRLSNLVQDLMTLSRVQGD 222

CP001738_4663: domain 1 of 1, from 233 to 298: score 59.0, E = 2.8e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f++++sHELRTP++a+r+++e + + ++ + +
CP001738_4 233 RQRQFASDASHELRTPIAALRANLEDAVM---------HPEDTDL-- 268

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e ++ +lr+++rl+++i dlL l+ri+++
CP001738_4 269 ----------QEVVRAALRDTDRLESIITDLLLLARIGTE 298

CP001738_4040: domain 1 of 1, from 202 to 268: score 54.4, E = 5.2e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a +ef+a++sH+LRTPLta+++ +e + + ++ +e +
CP001738_4 202 ASREFAADASHQLRTPLTALSMRLEEMVR---------SADQPEVV- 238

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
re +l++aerl + +++lL +r +
CP001738_4 239 ----------REEGAAALSQAERLVAVVEQLLARARHDRT 268

CP001738_1101: domain 1 of 1, from 320 to 388: score 51.0, E = 5.1e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+ +sH+L PL + ++++L++++ +++ +e
CP001738_1 320 ELEQFAYVASHDLQEPLRKVASFCQMLERRY-------GDRLDERG- 358

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+y++ + + a+r+++Li+dlL lsr +
CP001738_1 359 ----------RRYIDFAVDGAKRMQALISDLLMLSRVGRS 388

CP001738_1661: domain 1 of 1, from 192 to 258: score 50.4, E = 7.3e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+++f+an+sHELRTPL+ r+++e++l d+e+s++
CP001738_1 192 AQRRFVANASHELRTPLAINRTLLEVALG--------DPEASPDL-- 228

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +t+l r +rLi+ lL l+r e +
CP001738_1 229 ----------KAVGRTLLANNARHERLIEGLLLLARSERE 258

CP001738_0449: domain 1 of 1, from 234 to 299: score 49.9, E = 1e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+a++sH+LRTP++a r+ +e +l ++ +t++++
CP001738_0 234 QMRRFTADASHDLRTPIAAARARVEEALL-----YPDETDWPAMA-- 273

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+l++++rl++++ dlL+l+ +++
CP001738_0 274 --------------TDVLESLNRLQAIVTDLLELAALDSK 299

CP001738_3291: domain 1 of 1, from 223 to 278: score 44.7, E = 3.1e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a +e++a+lsH LRTPL+a+r++ae L ++l++++
CP001738_3 223 AEREMAADLSHRLRTPLAALRLNAESLPP---------GALGDQT-- 258

peLRledpeyreyletilreaerllrLind<-*
re++++++re++ + r +++
CP001738_3 259 ----------REAVDRLEREIDMIIRAVRN 278


Histogram of all scores:
score obs exp (one = represents 17 sequences)
----- --- ---
-15 1 0|=
-14 16 0|=
-13 50 3|*==
-12 179 111|======*====
-11 430 579|========================== *
-10 814 1075|================================================ *
-9 977 1110|==========================================================*
-8 840 831|================================================*=
-7 590 524|==============================*====
-6 409 301|=================*=======
-5 245 165|=========*=====
-4 144 88|=====*===
-3 80 46|==*==
-2 41 24|=*=
-1 17 12|*
0 21 6|*=
1 9 3|*
2 5 1|*
3 3 0|=
4 0 0|
5 1 0|=
6 0 0|
> 7 18 -|==


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 345.0056
P(chi-square) = 0

Total sequences searched: 4890

Whole sequence top hits:
tophits_s report:
Total hits: 16
Satisfying E cutoff: 16
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 16
Satisfying E cutoff: 16
Total memory: 27K


Acknowledgements:

This research is funded by:

Developed by: