Acidobacteria Actinobacteria Alphaproteobacteria
Aquificae Bacteroidetes/Chlorobi Betaproteobacteria
Chlamydiae/Verrucomicrobia Chloroflexi Cyanobacteria
Deinococcus-Thermus Deltaproteobacteria Epsilonproteobacteria
Firmicutes Fusobacteria Gammaproteobacteria
Other Bacteria Planctomycetes Spirochaetes
Thermotogae
Classification of phyla is from NCBI page
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14 projects found  

2 accessions found for Sphaerobacter thermophilus DSM 20745  

Data for CP001823  

Available Atlases
Other Plots
hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
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HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: CP001823.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
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Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
CP001823_0368 CDS_409485-407689 83.2 1.9e-23 1
CP001823_2183 CDS_2449676-2451292 81.8 4.6e-23 1
CP001823_2017 CDS_2251194-2249713 76.8 1.2e-21 1
CP001823_2388 CDS_2680388-2682754 76.5 1.4e-21 1
CP001823_1933 CDS_2149290-2150390 74.1 6.8e-21 1
CP001823_0909 CDS_1001220-1002851 67.3 5.8e-19 1
CP001823_2379 CDS_2667915-2672261 66.8 8e-19 1
CP001823_0748 CDS_833964-832570 65.9 1.5e-18 1
CP001823_0181 CDS_204323-202890 65.9 1.5e-18 1
CP001823_2022 CDS_2256059-2254908 64.8 3.1e-18 1
CP001823_2030 CDS_2265801-2264230 63.8 5.9e-18 1
CP001823_2433 CDS_2735028-2733754 45.9 6.9e-13 1
CP001823_1265 CDS_1403152-1404855 42.1 8.2e-12 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CP001823_0368 1/1 360 427 .. 1 87 [] 83.2 1.9e-23
CP001823_2183 1/1 301 369 .. 1 87 [] 81.8 4.6e-23
CP001823_2017 1/1 247 317 .. 1 87 [] 76.8 1.2e-21
CP001823_2388 1/1 545 616 .. 1 87 [] 76.5 1.4e-21
CP001823_1933 1/1 133 201 .. 1 87 [] 74.1 6.8e-21
CP001823_0909 1/1 305 381 .. 1 87 [] 67.3 5.8e-19
CP001823_2379 1/1 1210 1280 .. 1 87 [] 66.8 8e-19
CP001823_0748 1/1 233 300 .. 1 87 [] 65.9 1.5e-18
CP001823_0181 1/1 228 295 .. 1 87 [] 65.9 1.5e-18
CP001823_2022 1/1 156 224 .. 1 87 [] 64.8 3.1e-18
CP001823_2030 1/1 303 370 .. 1 87 [] 63.8 5.9e-18
CP001823_2433 1/1 193 261 .. 1 87 [] 45.9 6.9e-13
CP001823_1265 1/1 339 405 .. 1 87 [] 42.1 8.2e-12

Alignments of top-scoring domains:
CP001823_0368: domain 1 of 1, from 360 to 427: score 83.2, E = 1.9e-23
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++f+an+sHELRTP++++++++e+Ll+ ++l +e+++
CP001823_0 360 IRRDFVANVSHELRTPIASLKALVETLLD---------GALEDEEVA 397

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e+l +++ e++ l rL++dlL+lsr+e+g
CP001823_0 398 ----------HEFLARMETEVDGLARLVQDLLELSRAESG 427

CP001823_2183: domain 1 of 1, from 301 to 369: score 81.8, E = 4.6e-23
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++e++a++sHELRTP++++rgy+e +l+ ++ e +++++
CP001823_2 301 SQRELVAAVSHELRTPVATLRGYLESALA-------HWNEEPPPTL- 339

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r l ++ re+e+l+rLi+dl +lsr eag
CP001823_2 340 ----------RADLAIMARETEQLQRLIDDLFTLSRVEAG 369

CP001823_2017: domain 1 of 1, from 247 to 317: score 76.8, E = 1.2e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a ++f++++sHELRTPLta+rg+ae+Ll++ d + +++ ++
CP001823_2 247 AERRFVSDASHELRTPLTALRGNAEILLRQID-----AERWDPADL- 287

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+ l i++eaer+ rL+++lL+l+r++ g
CP001823_2 288 ----------RDGLADIRDEAERMGRLVENLLTLARADVG 317

CP001823_2388: domain 1 of 1, from 545 to 616: score 76.5, E = 1.4e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++efl+ ++HEL+TP+t+++++++ +l+ +l+++++l +e +
CP001823_2 545 QREEFLSIAAHELKTPVTSVKLFTQGMLR----TLQRRGTLAPERA- 586

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ l+til++++rl rL++dlLd sr ++g
CP001823_2 587 ----------ERDLQTILSQIDRLTRLVDDLLDVSRVRTG 616

CP001823_1933: domain 1 of 1, from 133 to 201: score 74.1, E = 6.8e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+s+++a lsHE+RTPL++I+gya++Ll +d+ ++ee+r
CP001823_1 133 LRSDLAAILSHEMRTPLASIKGYASALLL-------EDAYWDEETR- 171

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
re+l i+ e+++l +Li+d+Ld s ieag
CP001823_1 172 ----------REFLLAIDAETDHLTQLIEDVLDASIIEAG 201

CP001823_0909: domain 1 of 1, from 305 to 381: score 67.3, E = 5.8e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldk....vlagdtelse
a+ f+an+sH+LRTP++ +rg++e Ll+ ++ ++ +++ +el++
CP001823_0 305 ARKAFVANVSHDLRTPVAIVRGHIERLLA--SRgadpISGSLGELDD 349

eqrlpeLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e+ + l ++++e+ l+rLindl +l+rie+
CP001823_0 350 EE------------TRSLAVVHQEVLTLERLINDLFTLARIEEA 381

CP001823_2379: domain 1 of 1, from 1210 to 1280: score 66.8, E = 8e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ fl+++sHEL+TPLt+++gy +lLl+ +++ ++l+ e++
CP001823_2 1210 VREAFLSTASHELKTPLTTVKGYGQLLLR-----FLKQPTLDREHL- 1250

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ ++++++r + L+ndlLd sri++g
CP001823_2 1251 ----------IKLATHLRDQTDRFETLVNDLLDVSRIQQG 1280

CP001823_0748: domain 1 of 1, from 233 to 300: score 65.9, E = 1.5e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++ f+a++sHELRTPLt +r++ae+Ll+ +++ ++e+
CP001823_0 233 RQQAFIADASHELRTPLTLLRANAEVLLR-------RRDRFDPED-- 270

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +le i e+ ++++L ++lL+l+r++a+
CP001823_0 271 ----------AALLEDIVAETAHMDHLASNLLTLARLDAN 300

CP001823_0181: domain 1 of 1, from 228 to 295: score 65.9, E = 1.5e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++ f+ ++ H+LRTPL a+rgy+e L+++l + ++e+r
CP001823_0 228 ERRLFIGAVVHDLRTPLFALRGYLEGLEKGL--------DDTPEKR- 265

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++y+ ++++ a l+rLi dl d++r+e
CP001823_0 266 ----------ARYIAVAQEKAATLERLIGDLFDFTRLEYL 295

CP001823_2022: domain 1 of 1, from 156 to 224: score 64.8, E = 3.1e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++ f+a++ HELR+PLt+I gya+ L+++ + ++l e++
CP001823_2 156 QLQVFIAAVTHELRQPLTTIVGYAQGLQRRIE------PDLAEQD-- 194

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r++le i++++ r +r+ dl d +r++ g
CP001823_2 195 ----------RRALEAIIEAVWRTRRITTDLHDAARLGVG 224

CP001823_2030: domain 1 of 1, from 303 to 370: score 63.8, E = 5.9e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+k++fla ++HELRTPLt+Irg+++l+ + ++++ +e++
CP001823_2 303 EKDDFLAVAAHELRTPLTTIRGHLQLIMR--------RADRLPEDI- 340

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r +e++++++er+ ++ +lLd sri+
CP001823_2 341 ----------RGRIEIVQEQVERMTQMAVRLLDVSRIGMD 370

CP001823_2433: domain 1 of 1, from 193 to 261: score 45.9, E = 6.9e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ ++a l+HELRTPLt++rg+++l+ +a+ ++ + ++
CP001823_2 193 TMTTLVAQLAHELRTPLTGLRGNVQLAAI-----AARKGDYTRVPAR 234

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
le + r ++ + i++l dlsr+e g
CP001823_2 235 -------------LEAAMRLVDTMTGVIQNLQDLSRLERG 261

CP001823_1265: domain 1 of 1, from 339 to 405: score 42.1, E = 8.2e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k +f+a+++HEL PL+aIr ++elL + + ++e r
CP001823_1 339 LKADFTAMVAHELGYPLSAIRRLTELLAR---------DGVNPELR- 375

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ l +ilre++ l+ L+ d+ ++ e
CP001823_1 376 ----------NRTLASILRETDALDTLVADVQAMATVERD 405


Histogram of all scores:
score obs exp (one = represents 8 sequences)
----- --- ---
-14 6 0|=
-13 21 1|*==
-12 99 55|======*======
-11 194 289|========================= *
-10 383 536|================================================ *
-9 458 553|==========================================================*
-8 450 414|===================================================*=====
-7 321 261|================================*========
-6 193 150|==================*======
-5 105 82|==========*===
-4 75 44|=====*====
-3 41 23|==*===
-2 33 12|=*===
-1 17 6|*==
0 9 3|*=
1 8 1|*
2 4 0|=
3 4 0|=
4 2 0|=
5 0 0|
> 6 16 -|==


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 247.8722
P(chi-square) = 0

Total sequences searched: 2439

Whole sequence top hits:
tophits_s report:
Total hits: 13
Satisfying E cutoff: 13
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 13
Satisfying E cutoff: 13
Total memory: 26K


Acknowledgements:

This research is funded by:

Developed by: