Acidobacteria Actinobacteria Alphaproteobacteria
Aquificae Bacteroidetes/Chlorobi Betaproteobacteria
Chlamydiae/Verrucomicrobia Chloroflexi Cyanobacteria
Deinococcus-Thermus Deltaproteobacteria Epsilonproteobacteria
Firmicutes Fusobacteria Gammaproteobacteria
Other Bacteria Planctomycetes Spirochaetes
Thermotogae
Classification of phyla is from NCBI page
Search:
264 projects found  

1 accessions found for Legionella pneumophila 2300/99 Alcoy  

Data for CP001828  

Available Atlases
Other Plots
hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
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HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: CP001828.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
CP001828_2228 CDS_2463337-2460887 99.2 7e-28 2
CP001828_2008 CDS_2219160-2221889 99.0 8e-28 1
CP001828_2265 CDS_2541313-2543343 70.8 7.7e-20 1
CP001828_1308 CDS_1420886-1422472 60.1 8.6e-17 1
CP001828_1380 CDS_1497516-1496101 56.6 8.2e-16 1
CP001828_1520 CDS_1651297-1649930 52.0 1.7e-14 1
CP001828_1857 CDS_2044037-2043015 47.4 3.4e-13 1
CP001828_0805 CDS_877285-876188 45.9 9.1e-13 1
CP001828_2595 CDS_2890120-2888843 35.7 7e-10 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CP001828_2008 1/1 296 361 .. 1 87 [] 99.0 8e-28
CP001828_2228 1/2 194 260 .. 1 87 [] 71.0 6.9e-20
CP001828_2265 1/1 280 338 .. 1 80 [. 70.8 7.7e-20
CP001828_1308 1/1 310 376 .. 1 87 [] 60.1 8.6e-17
CP001828_1380 1/1 246 311 .. 1 87 [] 56.6 8.2e-16
CP001828_1520 1/1 231 295 .. 1 87 [] 52.0 1.7e-14
CP001828_1857 1/1 123 189 .. 1 87 [] 47.4 3.4e-13
CP001828_0805 1/1 138 204 .. 1 87 [] 45.9 9.1e-13
CP001828_2595 1/1 205 273 .. 1 87 [] 35.7 7e-10
CP001828_2228 2/2 592 660 .. 1 87 [] 28.2 9.2e-08

Alignments of top-scoring domains:
CP001828_2008: domain 1 of 1, from 296 to 361: score 99.0, E = 8e-28
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ksef+an+sHE+RTP+++++g++ +Lle ++l++ q
CP001828_2 296 QKSEFIANMSHEIRTPMNGVIGFTNVLLE---------SKLDPLQ-- 331

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+y++ti+++a+ ll++ind+Ld+s+i+ag
CP001828_2 332 ----------LDYVKTIKSSAQDLLSIINDILDFSKIDAG 361

CP001828_2228: domain 1 of 2, from 194 to 260: score 71.0, E = 6.9e-20
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k++f+an+sHELRTPL I+g +e+Ll+ + l++
CP001828_2 194 IKTQFFANVSHELRTPLMLILGSLEMLLA--------EKRLPSFV-- 230

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
l++i++ a+ ll+ +ndlL +s+++ag
CP001828_2 231 ----------LNTLRRIQNNAQILLKHVNDLLNISKLDAG 260

CP001828_2265: domain 1 of 1, from 280 to 338: score 70.8, E = 7.7e-20
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
ak+ f+an+sH++RTPLt+++g++elL++ t +++eq
CP001828_2 280 AKTAFIANMSHDIRTPLTGVIGMSELLEN---------TVKDPEQ-- 315

peLRledpeyreyletilreaerllrLindlLd<-*
+e + +++++e ll+++nd+Ld
CP001828_2 316 ----------KEEAHMLHDSGEELLNMLNDILD 338

CP001828_1308: domain 1 of 1, from 310 to 376: score 60.1, E = 8.6e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+++f a+++HELR+PL aI +++l ++ ++l+ee
CP001828_1 310 ALGRFSASIAHELRNPLGAIAHAIQLFGDN--------EDLNEEN-- 346

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ + i + er++r i ++L+lsr e
CP001828_1 347 ----------TRLKQLIMNNCERMNRVIKNVLQLSRREKS 376

CP001828_1380: domain 1 of 1, from 246 to 311: score 56.6, E = 8.2e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ +f+a+++HELRTPL+a+++ a+++l+ ++ ee+
CP001828_1 246 REKRFAADAAHELRTPLAALKAQAQVALN---------SNDIEEK-- 281

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++l++++ +++r +++++lL++s++ +
CP001828_1 282 ----------NQALQKLIASVNRSTHIVQQLLTMSKLVPE 311

CP001828_1520: domain 1 of 1, from 231 to 295: score 52.0, E = 1.7e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+k++++ ++sHELR PL+ ++ ++el +++ +l + +
CP001828_1 231 SKERLIQDISHELRSPLARLKIAIELGKKKT-------KHLADNE-- 268

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +++ e+ rl++Li ++Ld++r+e
CP001828_1 269 -------------FARMEIETSRLNDLIGEILDFARLEKS 295

CP001828_1857: domain 1 of 1, from 123 to 189: score 47.4, E = 3.4e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ + ++a l+H++RTPL++ ++y+e L + + l+
CP001828_1 123 SIGTMTAQLAHQIRTPLSSAILYTEHLNN--------LPSLDHRI-- 159

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +++++++ +++++i+dlL ++r +
CP001828_1 160 ----------KNWIHRLQECHASIEQQIQDLLLFARGTSI 189

CP001828_0805: domain 1 of 1, from 138 to 204: score 45.9, E = 9.1e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+f a+++HELR+P++ +r+++e+ l+ +++ e+
CP001828_0 138 HIKQFSASIAHELRNPIHYLRTATEITLT---------KPQTIET-- 173

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
y+ l+t l+e ++l +Li++lL l+r e+g
CP001828_0 174 ---------YQHVLQTHLEEYQSLTQLIDNLLFLTRCEHG 204

CP001828_2595: domain 1 of 1, from 205 to 273: score 35.7, E = 7e-10
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ef +sH+L+ PL aI+ +a ++e+ +l++
CP001828_2 205 DLEEFSYIISHDLKAPLRAIIQLATWIEEDCG------NKLDSLS-- 243

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+ l+ +++ ++r++ +++ lL+++r++
CP001828_2 244 ----------RKNLQLLRERTRRMSGMVDGLLQYARAGRV 273

CP001828_2228: domain 2 of 2, from 592 to 660: score 28.2, E = 9.2e-08
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+ ++sH+L+ PL a+ +++ ++e+l +e+ +eq
CP001828_2 592 ELDQFVYHASHDLKAPLPAMEHLISWIEEDL-------GEMLSEQS- 630

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++yl +++ a r+++L++ lL +++ +
CP001828_2 631 ----------KKYLLLLRQRASRMSKLLDGLLKYAQSGYV 660


Histogram of all scores:
score obs exp (one = represents 11 sequences)
----- --- ---
-15 2 0|=
-14 15 0|==
-13 73 2|*======
-12 185 72|======*==========
-11 334 378|=============================== *
-10 504 701|============================================== *
-9 614 724|======================================================== *
-8 504 542|============================================== *
-7 371 341|==============================*===
-6 240 196|=================*====
-5 136 107|=========*===
-4 87 57|=====*==
-3 45 30|==*==
-2 31 16|=*=
-1 20 8|*=
0 7 4|*
1 5 2|*
2 3 1|*
3 2 0|=
4 1 0|=
5 0 0|
> 6 12 -|==


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 323.8521
P(chi-square) = 0

Total sequences searched: 3191

Whole sequence top hits:
tophits_s report:
Total hits: 9
Satisfying E cutoff: 9
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 10
Satisfying E cutoff: 10
Total memory: 24K


Acknowledgements:

This research is funded by:

Developed by: