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Thermotogae
Classification of phyla is from NCBI page
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264 projects found  

2 accessions found for Escherichia coli O55:H7 str. CB9615  

Data for CP001846  

Available Atlases
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hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: CP001846.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
CP001846_3291 CDS_3475533-3478289 100.1 6.1e-28 1
CP001846_0479 CDS_519555-520850 91.0 2.4e-25 1
CP001846_2782 CDS_2953577-2957170 81.6 1.1e-22 1
CP001846_1167 CDS_1281889-1279145 80.7 1.9e-22 1
CP001846_2645 CDS_2793618-2790769 80.6 2.1e-22 1
CP001846_3760 CDS_3984063-3981727 78.9 6.4e-22 1
CP001846_2957 CDS_3152592-3151102 75.4 6.3e-21 1
CP001846_2495 CDS_2618445-2619848 69.8 2.5e-19 1
CP001846_4500 CDS_4792577-4791204 66.6 1.9e-18 1
CP001846_5010 CDS_5381396-5382820 62.4 2.9e-17 1
CP001846_4594 CDS_4898391-4899767 61.5 5.4e-17 1
CP001846_0696 CDS_766852-765404 61.0 7.5e-17 1
CP001846_3580 CDS_3799666-3801015 60.7 9.3e-17 1
CP001846_4455 CDS_4739522-4738473 59.7 1.8e-16 1
CP001846_0806 CDS_892304-889620 59.6 1.8e-16 1
CP001846_3916 CDS_4136682-4135330 55.0 3.7e-15 1
CP001846_2319 CDS_2432479-2431121 52.3 2.1e-14 1
CP001846_4704 CDS_5036496-5035396 45.0 2.6e-12 1
CP001846_1917 CDS_2039990-2041291 42.4 1.4e-11 1
CP001846_4683 CDS_5015233-5017590 36.1 8.5e-10 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CP001846_3291 1/1 292 357 .. 1 87 [] 100.1 6.1e-28
CP001846_0479 1/1 203 269 .. 1 87 [] 91.0 2.4e-25
CP001846_2782 1/1 711 777 .. 1 87 [] 81.6 1.1e-22
CP001846_1167 1/1 443 508 .. 1 87 [] 80.7 1.9e-22
CP001846_2645 1/1 469 534 .. 1 87 [] 80.6 2.1e-22
CP001846_3760 1/1 282 347 .. 1 87 [] 78.9 6.4e-22
CP001846_2957 1/1 270 338 .. 1 87 [] 75.4 6.3e-21
CP001846_2495 1/1 240 304 .. 1 87 [] 69.8 2.5e-19
CP001846_4500 1/1 238 300 .. 1 87 [] 66.6 1.9e-18
CP001846_5010 1/1 255 320 .. 1 87 [] 62.4 2.9e-17
CP001846_4594 1/1 237 303 .. 1 87 [] 61.5 5.4e-17
CP001846_0696 1/1 261 327 .. 1 87 [] 61.0 7.5e-17
CP001846_3580 1/1 236 302 .. 1 87 [] 60.7 9.3e-17
CP001846_4455 1/1 129 186 .. 1 79 [. 59.7 1.8e-16
CP001846_0806 1/1 663 730 .. 1 87 [] 59.6 1.8e-16
CP001846_3916 1/1 233 293 .. 1 87 [] 55.0 3.7e-15
CP001846_2319 1/1 235 301 .. 1 87 [] 52.3 2.1e-14
CP001846_4704 1/1 145 205 .. 1 87 [] 45.0 2.6e-12
CP001846_1917 1/1 211 271 .. 1 87 [] 42.4 1.4e-11
CP001846_4683 1/1 429 491 .. 1 87 [] 36.1 8.5e-10

Alignments of top-scoring domains:
CP001846_3291: domain 1 of 1, from 292 to 357: score 100.1, E = 6.1e-28
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
kseflan+sHELRTPL++++g++ l l+ tel++ q
CP001846_3 292 IKSEFLANMSHELRTPLNGVIGFTRLTLK---------TELTPTQ-- 327

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+ l+ti+r+a+ ll++ind+Ld+s++eag
CP001846_3 328 ----------RDHLNTIERSANNLLAIINDVLDFSKLEAG 357

CP001846_0479: domain 1 of 1, from 203 to 269: score 91.0, E = 2.4e-25
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++ f+an+sHELRTPLt+++gy+e++ e ++l r
CP001846_0 203 ARRNFFANVSHELRTPLTVLQGYLEMMDE---------QPLEGAVR- 239

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l+t++++++r++ L+ +lL+ls+iea
CP001846_0 240 ----------EKALHTMREQTQRMEGLVKQLLTLSKIEAA 269

CP001846_2782: domain 1 of 1, from 711 to 777: score 81.6, E = 1.1e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks+fla++sHE+RTP+++I+g++elL + ls eqr
CP001846_2 711 AKSQFLATMSHEIRTPISSIMGFLELLSG---------SGLSKEQR- 747

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e+++ ++ +++ll Li ++Ld +ie+g
CP001846_2 748 ----------VEAISLAYATGQSLLGLIGEILDVDKIESG 777

CP001846_1167: domain 1 of 1, from 443 to 508: score 80.7, E = 1.9e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks fla++sHE+RTPL +I+g+a+lL + ++ q
CP001846_1 443 AKSAFLAAMSHEIRTPLYGILGTAQLLAD---------NPALNAQ-- 478

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+ l+ i +++e+ll ++nd+Ld+s ieag
CP001846_1 479 ----------RDDLRAITDSGESLLTILNDILDYSAIEAG 508

CP001846_2645: domain 1 of 1, from 469 to 534: score 80.6, E = 2.1e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ks fla++sHELRTPL +I+g+++lL++ el+
CP001846_2 469 SKSMFLATVSHELRTPLYGIIGNLDLLQT---------KELPKGV-- 504

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ + +++ ll++i+d+Ld+s+ie++
CP001846_2 505 ----------DRLVTAMNNSSSLLLKIISDILDFSKIESE 534

CP001846_3760: domain 1 of 1, from 282 to 347: score 78.9, E = 6.4e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k+ f++++sHELRTPL++I g++ +Ll+ tel++eq
CP001846_3 282 DKTTFISTISHELRTPLNGIVGLSRILLD---------TELTAEQ-- 317

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++yl+ti+ +a l ++ nd+ d+ ++e
CP001846_3 318 ----------EKYLKTIHVSAVTLGNIFNDIIDMDKMERR 347

CP001846_2957: domain 1 of 1, from 270 to 338: score 75.4, E = 6.3e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +fl++lsHEL+TPL+++r +elL +++ ++l++eq
CP001846_2 270 QRHQFLRHLSHELKTPLASMREGTELLADQV------VGPLTPEQ-- 308

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e +++++++++ l++Li++lLd+ r +a
CP001846_2 309 ----------KEVVSILDSSSRNLQKLIEQLLDYNRKQAD 338

CP001846_2495: domain 1 of 1, from 240 to 304: score 69.8, E = 2.5e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+a++sHELRTPL+++rg +e++++++ + ++e+
CP001846_2 240 MRRDFMADISHELRTPLAVLRGELEAIQDGV-------RKFTPET-- 277

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +++ e+ l +L++dl +ls ++g
CP001846_2 278 -------------VASLQAEVGTLTKLVDDLHQLSMSDEG 304

CP001846_4500: domain 1 of 1, from 238 to 300: score 66.6, E = 1.9e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++++l+++sHELRTPLt +++ + lL++ +++
CP001846_4 238 SQQRLLSDISHELRTPLTRLQLGTALLRR---------RSGESKE-- 273

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
le+i+ ea+rl+++indlL +sr ++
CP001846_4 274 -------------LERIETEAQRLDSMINDLLVMSRNQQK 300

CP001846_5010: domain 1 of 1, from 255 to 320: score 62.4, E = 2.9e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ + +l HEL+ PL+aIrg+ae+L+e ++ +e
CP001846_5 255 YIEQYVYALTHELKSPLAAIRGAAEILRE---------GPPPEVV-- 290

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++++ il + r+++L++ lL +r+e+
CP001846_5 291 ----------ARFTDNILTQNARMQALVETLLRQARLENR 320

CP001846_4594: domain 1 of 1, from 237 to 303: score 61.5, E = 5.4e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++ ++a+++HE+R+PL++I+g+a+ e +++++ e
CP001846_4 237 ALGHLAAGVAHEIRNPLSSIKGLAKYFAE--------RAPAGGEA-- 273

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ +++ +ea+rl+r +++lL+l + +
CP001846_4 274 ----------HQLAQVMAKEADRLNRVVSELLELVKPTHL 303

CP001846_0696: domain 1 of 1, from 261 to 327: score 61.0, E = 7.5e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++s f a+++HE+RTP+t +++ +e++l + +s +++
CP001846_0 261 RQSNFSADIAHEIRTPITNLITQTEIALS---------QSRSQKEL- 297

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ l + l+e+ r+ ++++d+L l++++++
CP001846_0 298 ----------EDVLYSNLEELTRMAKMVSDMLFLAQADNN 327

CP001846_3580: domain 1 of 1, from 236 to 302: score 60.7, E = 9.3e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++f+++++HELR PLta++ +e+++ ++ +++ r
CP001846_3 236 RERRFTSDAAHELRSPLTALKVQTEVAQL---------SDDDPQAR- 272

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l +++ ++r rL+++lL+lsr+++
CP001846_3 273 ----------KKALLQLHSGIDRATRLVDQLLTLSRLDSL 302

CP001846_4455: domain 1 of 1, from 129 to 186: score 59.7, E = 1.8e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a ++++++l+HE+++PL ++rg+a+lL + +l+++ +
CP001846_4 129 AARDLVRGLAHEIKNPLGGLRGAAQLLSK----------ALPDPSL- 164

peLRledpeyreyletilreaerllrLindlL<-*
ey+++i+++a+rl++L+++lL
CP001846_4 165 ----------LEYTKVIIEQADRLRNLVDRLL 186

CP001846_0806: domain 1 of 1, from 663 to 730: score 59.6, E = 1.8e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +la+lsH+LRTPLt++ g ae+L +l + ++++
CP001846_0 663 IRNALLAALSHDLRTPLTVLFGQAEILTLDL-------ASEGSPH-- 700

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ + i++ + rL+n+lLd++ri++g
CP001846_0 701 ----------ARQASEIRQHVLNTTRLVNNLLDMARIQSG 730

CP001846_3916: domain 1 of 1, from 233 to 293: score 55.0, E = 3.7e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ ++a++sH+LRTPLt Ir+++e++ e ++
CP001846_3 233 DRTLLMAGVSHDLRTPLTRIRLATEMMSE---------QD------- 263

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ e+i +++e ++++i+++ d+ r +++
CP001846_3 264 ----------GYLAESINKDIEECNAIIEQFIDYLRTGQE 293

CP001846_2319: domain 1 of 1, from 235 to 301: score 52.3, E = 2.1e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++s+f+ +l+HELRTP++a++g ++ l +++s +
CP001846_2 235 RLSQFADDLAHELRTPINALLGQNQVTLS---------QTRSIAE-- 270

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
y++ + ++e+e ++rL +++L l+r++ +
CP001846_2 271 ---------YQKTIAGNIEELENISRLTENILFLARADKN 301

CP001846_4704: domain 1 of 1, from 145 to 205: score 45.0, E = 2.6e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ f+a+++HELRTPL+++r+++elL + t+
CP001846_4 145 NERLFTADVAHELRTPLAGVRLHLELLAK---------TH------- 175

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + + ++++ + +++lL+l+r+++
CP001846_4 176 ----------HIDVAPLVARLDQMMESVSQLLQLARAGQS 205

CP001846_1917: domain 1 of 1, from 211 to 271: score 42.4, E = 1.4e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+k +++ +++HELRTPL +r +e+ + ls+ +
CP001846_1 211 SKKQLIDGIAHELRTPLVRLRYRLEMSDN-----------LSAAE-- 244

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + r++ +l++Li++lL+++r++ +
CP001846_1 245 -------------SQALNRDISQLEALIEELLTYARLDRP 271

CP001846_4683: domain 1 of 1, from 429 to 491: score 36.1, E = 8.5e-10
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a ++++ +l+H++++ L++I+g +el + +++
CP001846_4 429 AVGQLTGGLAHDFNNLLAVIIGSLELVNP---------DSPDAPR-- 464

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++++l++aer L ++lL +sr ++
CP001846_4 465 -------------IQRALQAAERGALLTQRLLAFSRKQSL 491


Histogram of all scores:
score obs exp (one = represents 17 sequences)
----- --- ---
-16 2 0|=
-15 4 0|=
-14 28 0|==
-13 87 3|*=====
-12 249 114|======*========
-11 522 594|=============================== *
-10 859 1102|=================================================== *
-9 986 1138|==========================================================*
-8 816 852|================================================ *
-7 577 537|===============================*==
-6 363 309|==================*===
-5 219 169|=========*===
-4 119 90|=====*=
-3 62 47|==*=
-2 32 25|=*
-1 34 13|*=
0 16 6|*
1 8 3|*
2 6 1|*
3 2 0|=
4 0 0|
5 1 0|=
6 0 0|
> 7 22 -|==


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 328.9489
P(chi-square) = 0

Total sequences searched: 5014

Whole sequence top hits:
tophits_s report:
Total hits: 20
Satisfying E cutoff: 20
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 20
Satisfying E cutoff: 20
Total memory: 28K


Acknowledgements:

This research is funded by:

Developed by: