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106 projects found  

1 accessions found for Thermobispora bispora DSM 43833  

Data for CP001874  

Available Atlases
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hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: CP001874.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
CP001874_0180 CDS_222911-219267 90.8 1.9e-25 1
CP001874_3228 CDS_3829736-3828273 79.9 2.4e-22 1
CP001874_3048 CDS_3623752-3625200 73.8 1.2e-20 1
CP001874_0489 CDS_547213-548388 72.7 2.5e-20 1
CP001874_0758 CDS_862517-864301 72.7 2.6e-20 1
CP001874_2013 CDS_2365495-2364404 70.8 9.1e-20 1
CP001874_1864 CDS_2184373-2185803 69.8 1.7e-19 1
CP001874_0469 CDS_528007-529689 68.8 3.3e-19 1
CP001874_0039 CDS_47942-46026 55.2 2.3e-15 1
CP001874_3082 CDS_3667359-3668831 53.7 6.4e-15 1
CP001874_2270 CDS_2671779-2670376 47.2 4.3e-13 1
CP001874_3325 CDS_3948882-3950279 46.0 9.4e-13 1
CP001874_2287 CDS_2691982-2693334 45.4 1.4e-12 1
CP001874_0696 CDS_783575-784873 44.8 2.1e-12 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CP001874_0180 1/1 769 837 .. 1 87 [] 90.8 1.9e-25
CP001874_3228 1/1 249 313 .. 1 87 [] 79.9 2.4e-22
CP001874_3048 1/1 262 329 .. 1 87 [] 73.8 1.2e-20
CP001874_0489 1/1 152 218 .. 1 87 [] 72.7 2.5e-20
CP001874_0758 1/1 305 372 .. 1 87 [] 72.7 2.6e-20
CP001874_2013 1/1 140 208 .. 1 87 [] 70.8 9.1e-20
CP001874_1864 1/1 236 299 .. 1 87 [] 69.8 1.7e-19
CP001874_0469 1/1 206 274 .. 1 87 [] 68.8 3.3e-19
CP001874_0039 1/1 398 466 .. 1 87 [] 55.2 2.3e-15
CP001874_3082 1/1 251 316 .. 1 87 [] 53.7 6.4e-15
CP001874_2270 1/1 235 301 .. 1 87 [] 47.2 4.3e-13
CP001874_3325 1/1 219 284 .. 1 87 [] 46.0 9.4e-13
CP001874_2287 1/1 234 299 .. 1 87 [] 45.4 1.4e-12
CP001874_0696 1/1 209 275 .. 1 87 [] 44.8 2.1e-12

Alignments of top-scoring domains:
CP001874_0180: domain 1 of 1, from 769 to 837: score 90.8, E = 1.9e-25
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
kseflan+sHELRTPL++++ +a+lL ++++ ++l++ q
CP001874_0 769 YKSEFLANMSHELRTPLNSLLVLAKLLADNAE------GNLTPRQ-- 807

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e+ +ti++++ ll+Lind+Ldls+ eag
CP001874_0 808 ----------VEFAKTIHEAGTALLQLINDILDLSKVEAG 837

CP001874_3228: domain 1 of 1, from 249 to 313: score 79.9, E = 2.4e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+a++sHELRTPLt+Irg+ae ++ + s+++
CP001874_3 249 RMRRFVADASHELRTPLTSIRGFAEFYRR---------VPGSDPD-- 284

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ +i++ea r++ L++dlL l+r++++
CP001874_3 285 -----------RLMARIESEATRMSLLVEDLLLLARLDQQ 313

CP001874_3048: domain 1 of 1, from 262 to 329: score 73.8, E = 1.2e-20
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++f+a++sHELRTPL+a+ + +++L ee+ l+++
CP001874_3 262 MSRRFVADVSHELRTPLAAMTAVTDMLSEEA-------KSLPDDV-- 299

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e++++++re+erl+ L++ l ++sr ++g
CP001874_3 300 ----------GEAVQIVIREIERLQVLVDHLIEISRFDSG 329

CP001874_0489: domain 1 of 1, from 152 to 218: score 72.7, E = 2.5e-20
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++f+an+sHEL+TP+ a++++ae+ + ++ ++e +
CP001874_0 152 VRRDFVANVSHELKTPVGALSLLAETVMA---------AADDPEAV- 188

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r++ ++++ea rl +Li+dl +lsri+ g
CP001874_0 189 ----------RRFAGRMQHEAARLTNLIQDLITLSRIQGG 218

CP001874_0758: domain 1 of 1, from 305 to 372: score 72.7, E = 2.6e-20
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++f++++sHELRTPLt+Ir++a++L e +++ ++
CP001874_0 305 VQRQFVSDVSHELRTPLTTIRMAADVLYE-------SRESFDPGA-- 342

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ e +++++er ++++ dlL++sr +ag
CP001874_0 343 ----------ARAAELMQNQLERFEAMLTDLLEISRHDAG 372

CP001874_2013: domain 1 of 1, from 140 to 208: score 70.8, E = 9.1e-20
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +++++++HELR PLt+++g++ +Ll+ +++ ++ q+
CP001874_2 140 SRADLVSTVAHELRSPLTSVKGFTATLLA-------KWDRFTDAQK- 178

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+let+ +a+r rLi +lLd srie+g
CP001874_2 179 ----------LVMLETVNADADRVTRLITELLDVSRIESG 208

CP001874_1864: domain 1 of 1, from 236 to 299: score 69.8, E = 1.7e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+a++sHELRTP+++Ir+ +e ++ +e++
CP001874_1 236 QQRRFAADASHELRTPIAGIRAQLECARL-----------HPEDT-- 269

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e++e +lr+++rl++L++dlL l+ri++
CP001874_1 270 ----------AEAVEAALRDTDRLESLVSDLLLLTRIGTT 299

CP001874_0469: domain 1 of 1, from 206 to 274: score 68.8, E = 3.3e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+++f ++sHELRTPL++I+g++ lLl +g ++lseeq
CP001874_0 206 ARQRFWVSVSHELRTPLNSIIGLVRLLLG------PGGEPLSEEQ-- 244

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ ++ i ++ae ll+++++lLd++++e+g
CP001874_0 245 ----------EHQIRLIGSSAETLLAMVSELLDMAKAESG 274

CP001874_0039: domain 1 of 1, from 398 to 466: score 55.2, E = 2.3e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
ak+ fla HELRTP+t +rg+a++L + ++++ls+ +r
CP001874_0 398 AKDLFLAVTGHELRTPITIVRGFASTLDR-------RWDALSDAER- 436

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r +++ti + a+ l rL + lL +++++g
CP001874_0 437 ----------RSAVRTIAERANALGRLMDHLLLGAWAGTG 466

CP001874_3082: domain 1 of 1, from 251 to 316: score 53.7, E = 6.4e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++ef+a++sHELRTPL++Ir+ +e ++ +++ +
CP001874_3 251 RQREFTADASHELRTPLAGIRARLEDAKL---------HPAETDL-- 286

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e+++ +l ++erl+++i+dlL l+r a
CP001874_3 287 ----------EELVDGALGDVERLQAIIDDLLFLTRVCAA 316

CP001874_2270: domain 1 of 1, from 235 to 301: score 47.2, E = 4.3e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+++f+ n+sHELRTPL+ r+ +e++l+ ++ +e++
CP001874_2 235 AQRRFVDNASHELRTPLAITRTVLEVALA---------DPDASEDL- 271

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + +t+l + r +rLi+ lL l+r e +
CP001874_2 272 ----------KVLGRTLLGTTARNERLIEGLLLLARSERE 301

CP001874_3325: domain 1 of 1, from 219 to 284: score 46.0, E = 9.4e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++f++++sH+LR P+taIr+ +e +l + ++ +
CP001874_3 219 HQQRFTSDASHDLRSPITAIRAEVEDALL----------APDDRSV- 254

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e+ +til ++rl++ +ndlL +++++a
CP001874_3 255 ----------TELARTILGGIDRLQATVNDLLMIAQLDAR 284

CP001874_2287: domain 1 of 1, from 234 to 299: score 45.4, E = 1.4e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f++ +sH+LRTPLta+r+ +e +l ++ +++
CP001874_2 234 RQRRFAREASHDLRTPLTAMRADIEEALL---------HPEDADW-- 269

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + l+ ++rl+++i dlL+l+r+++g
CP001874_2 270 ----------PRVAQAQLDNIDRLQAIITDLLELARLDSG 299

CP001874_0696: domain 1 of 1, from 209 to 275: score 44.8, E = 2.1e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ +ef+ ++sH+LRTPLt++ + +e + + +++++e
CP001874_0 209 REREFATDASHQLRTPLTGLTMRLEEIVA--------SADRPEVV-- 245

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
re e ++ ++erl + i++lL +r +
CP001874_0 246 ----------REEGEAAIVQVERLTAVIDELLAAARRQRH 275


Histogram of all scores:
score obs exp (one = represents 12 sequences)
----- --- ---
-14 11 0|=
-13 30 2|*==
-12 129 81|======*====
-11 294 420|========================= *
-10 548 779|============================================== *
-9 685 805|==========================================================*
-8 661 602|==================================================*=====
-7 486 379|===============================*=========
-6 288 218|==================*=====
-5 182 119|=========*======
-4 94 64|=====*==
-3 57 33|==*==
-2 31 17|=*=
-1 19 9|*=
0 5 4|*
1 3 2|*
2 4 1|*
3 1 0|=
4 1 0|=
5 2 0|=
> 6 15 -|==


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 291.9421
P(chi-square) = 0

Total sequences searched: 3546

Whole sequence top hits:
tophits_s report:
Total hits: 14
Satisfying E cutoff: 14
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 14
Satisfying E cutoff: 14
Total memory: 26K


Acknowledgements:

This research is funded by:

Developed by: