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Thermotogae
Classification of phyla is from NCBI page
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264 projects found  

1 accessions found for Klebsiella variicola At-22  

Data for CP001891  

Available Atlases
Other Plots
hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: CP001891.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
CP001891_2955 CDS_3108413-3111100 107.1 6.6e-30 1
CP001891_0922 CDS_974008-971258 96.8 5.5e-27 1
CP001891_4004 CDS_4257006-4255711 91.9 1.3e-25 1
CP001891_0606 CDS_642916-639674 82.7 5.2e-23 1
CP001891_1405 CDS_1498611-1501451 79.4 4.7e-22 1
CP001891_0475 CDS_510886-513225 78.8 6.6e-22 1
CP001891_3450 CDS_3649914-3648442 78.7 7.2e-22 1
CP001891_1175 CDS_1243728-1245149 76.9 2.3e-21 1
CP001891_4955 CDS_5344353-5345726 66.1 2.7e-18 1
CP001891_4359 CDS_4659351-4657927 65.2 5e-18 1
CP001891_1523 CDS_1639544-1638042 63.0 2e-17 1
CP001891_4813 CDS_5175296-5173902 62.4 3.1e-17 1
CP001891_5002 CDS_5392187-5393236 60.3 1.2e-16 1
CP001891_4494 CDS_4813369-4811936 60.2 1.3e-16 1
CP001891_3622 CDS_3834252-3836939 59.2 2.4e-16 1
CP001891_0650 CDS_684923-683574 56.3 1.6e-15 1
CP001891_0323 CDS_365368-366723 53.8 8.1e-15 1
CP001891_1531 CDS_1653923-1652067 48.5 2.6e-13 1
CP001891_3540 CDS_3745381-3746478 46.5 9.9e-13 1
CP001891_2811 CDS_2950901-2952202 44.0 5e-12 1
CP001891_2595 CDS_2733702-2734898 43.4 7.1e-12 1
CP001891_4714 CDS_5053665-5051380 41.0 3.5e-11 1
CP001891_2471 CDS_2604136-2605479 32.9 6.7e-09 1
CP001891_3210 CDS_3370619-3372085 26.8 3.6e-07 2

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CP001891_2955 1/1 267 332 .. 1 87 [] 107.1 6.6e-30
CP001891_0922 1/1 292 357 .. 1 87 [] 96.8 5.5e-27
CP001891_4004 1/1 203 269 .. 1 87 [] 91.9 1.3e-25
CP001891_0606 1/1 596 662 .. 1 87 [] 82.7 5.2e-23
CP001891_1405 1/1 467 532 .. 1 87 [] 79.4 4.7e-22
CP001891_0475 1/1 282 347 .. 1 87 [] 78.8 6.6e-22
CP001891_3450 1/1 268 336 .. 1 87 [] 78.7 7.2e-22
CP001891_1175 1/1 249 317 .. 1 87 [] 76.9 2.3e-21
CP001891_4955 1/1 238 300 .. 1 87 [] 66.1 2.7e-18
CP001891_4359 1/1 255 320 .. 1 87 [] 65.2 5e-18
CP001891_1523 1/1 273 337 .. 1 87 [] 63.0 2e-17
CP001891_4813 1/1 241 307 .. 1 87 [] 62.4 3.1e-17
CP001891_5002 1/1 129 186 .. 1 79 [. 60.3 1.2e-16
CP001891_4494 1/1 258 324 .. 1 87 [] 60.2 1.3e-16
CP001891_3622 1/1 663 730 .. 1 87 [] 59.2 2.4e-16
CP001891_0650 1/1 236 302 .. 1 87 [] 56.3 1.6e-15
CP001891_0323 1/1 233 293 .. 1 87 [] 53.8 8.1e-15
CP001891_1531 1/1 398 463 .. 1 87 [] 48.5 2.6e-13
CP001891_3540 1/1 143 203 .. 1 87 [] 46.5 9.9e-13
CP001891_2811 1/1 211 271 .. 1 87 [] 44.0 5e-12
CP001891_2595 1/1 170 233 .. 1 87 [] 43.4 7.1e-12
CP001891_4714 1/1 402 464 .. 1 87 [] 41.0 3.5e-11
CP001891_2471 1/1 226 284 .. 1 87 [] 32.9 6.7e-09

Alignments of top-scoring domains:
CP001891_2955: domain 1 of 1, from 267 to 332: score 107.1, E = 6.6e-30
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks flan+sHE+RTP+++I+g+a+l+l+ t+l++eq
CP001891_2 267 AKSAFLANMSHEIRTPMNGILGMAQLCLD---------TPLTAEQ-- 302

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
reyl+ + ++a++ll++ind+Ld+srie+g
CP001891_2 303 ----------REYLSLVMSSAQSLLHIINDILDFSRIESG 332

CP001891_0922: domain 1 of 1, from 292 to 357: score 96.8, E = 5.5e-27
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
kseflan+sHELRTPL++++g++ l l+ t+l++ q
CP001891_0 292 IKSEFLANMSHELRTPLNGVIGFTRLTLK---------TDLNATQ-- 327

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+ l ti+r+a+ ll++ind+Ld+s++eag
CP001891_0 328 ----------RDHLTTIERSANNLLAIINDVLDFSKLEAG 357

CP001891_4004: domain 1 of 1, from 203 to 269: score 91.9, E = 1.3e-25
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++ f+an+sHELRTPLt+++gy+e+++e + l +r
CP001891_4 203 ARRNFFANVSHELRTPLTVLQGYLEMMQE---------QVLEGATR- 239

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l+t++++++r++ L+ +lL+lsriea
CP001891_4 240 ----------EKALHTMREQTQRMEGLVKQLLTLSRIEAA 269

CP001891_0606: domain 1 of 1, from 596 to 662: score 82.7, E = 5.2e-23
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks+fla++sHELRTP++aI g++elL + +el+ qr
CP001891_0 596 AKSRFLASMSHELRTPVSAIVGFLELLAK---------PELNVGQR- 632

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e++e + + a+ ll Li ++Ld+ +ie+g
CP001891_0 633 ----------KEAIELAGSTAQTLLGLIGNILDIDKIESG 662

CP001891_1405: domain 1 of 1, from 467 to 532: score 79.4, E = 4.7e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ks fla++sHELRTPL +I+g+++lL++ +l+
CP001891_1 467 SKSMFLATVSHELRTPLYGIIGNLDLLQT---------KALPKGV-- 502

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ + +++ ll++i+d+Ld+s+ie++
CP001891_1 503 ----------DRLVTAMNNSSSLLLKIISDILDFSKIESE 532

CP001891_0475: domain 1 of 1, from 282 to 347: score 78.8, E = 6.6e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k+ f++++sHELRTPL++I g++ +Ll+ tel++eq
CP001891_0 282 DKTTFISTISHELRTPLNGIVGLSRILLD---------TELTSEQ-- 317

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++yl+ti+ +a l ++ nd+ d+ ++e
CP001891_0 318 ----------EKYLKTIHVSAVTLGNIFNDIIDMDKMERR 347

CP001891_3450: domain 1 of 1, from 268 to 336: score 78.7, E = 7.2e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++ef+an+sH+LRTPLt+++gy+e+L +d+ l++e+r
CP001891_3 268 QRREFVANISHDLRTPLTSLLGYLETLML-------KDERLTAEER- 306

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+yl ++lr+++ ++L ++l +l+r+e+g
CP001891_3 307 ----------RQYLTIALRQGNKVRHLSQQLFELARLEHG 336

CP001891_1175: domain 1 of 1, from 249 to 317: score 76.9, E = 2.3e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +fl++lsHEL+TPL+++r +elL +++ ++l++eq
CP001891_1 249 QRHQFLRHLSHELKTPLASMREGTELLADRVA------GPLTPEQ-- 287

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e++e+++++++ l++Li++lLd+ r +a
CP001891_1 288 ----------QEIVEILDSSSRNLQKLIEQLLDYNRKQAD 317

CP001891_4955: domain 1 of 1, from 238 to 300: score 66.1, E = 2.7e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++++l+++sHELRTPLt +++ + lL++ +++
CP001891_4 238 SQQRLLSDISHELRTPLTRLQLGTALLRR---------RSGESKE-- 273

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
le+i+ ea+rl+++indlL +sr +a
CP001891_4 274 -------------LERIETEAHRLDSMINDLLVMSRNQAK 300

CP001891_4359: domain 1 of 1, from 255 to 320: score 65.2, E = 5e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a + + +l HEL+ PL+aIrg+ae+L+e ++ +e
CP001891_4 255 AIENYVYDLTHELKSPLAAIRGAAEILRE---------GPPPEVA-- 290

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++++ il + r++ L+++lL+ +r+e+
CP001891_4 291 ----------ARFTDNILAQNTRMQLLVERLLQQARLESR 320

CP001891_1523: domain 1 of 1, from 273 to 337: score 63.0, E = 2e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++++a++sHELRTPL+++rg +e++++++ ++e
CP001891_1 273 MRRDLMADISHELRTPLAVLRGELEAIQDGV-------RRFTPES-- 310

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +++ e+ l +L++dl +ls ++g
CP001891_1 311 -------------IPSLQAEVATLTKLVDDLHQLSMSDEG 337

CP001891_4813: domain 1 of 1, from 241 to 307: score 62.4, E = 3.1e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++ ++a+++HE+R+PL++I+g+a+ e +t+ + e
CP001891_4 241 ALGHLAAGVAHEIRNPLSSIKGLAKYFAE--------RTPPGGEA-- 277

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ +++ +ea+rl+r +++lL+l r +
CP001891_4 278 ----------QQLAQVMAKEADRLNRVVSELLELVRPAHL 307

CP001891_5002: domain 1 of 1, from 129 to 186: score 60.3, E = 1.2e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a ++++++l+HE+++PL ++rg+a+lL + +l+++ +
CP001891_5 129 AARDLVRGLAHEIKNPLGGLRGAAQLLSK----------ALPDPAL- 164

peLRledpeyreyletilreaerllrLindlL<-*
ey+++i+++a+rl++L+++lL
CP001891_5 165 ----------TEYTKVIIEQADRLRNLVDRLL 186

CP001891_4494: domain 1 of 1, from 258 to 324: score 60.2, E = 1.3e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++s f a+++HE+RTP+t + + +e++l + +s +++
CP001891_4 258 RQSNFSADIAHEIRTPITNLVTQTEIALS---------QSRSQQEL- 294

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e l + l+e r++r+++d+L l++++++
CP001891_4 295 ----------EEVLYSNLEEFSRMSRMVSDMLFLAQADNN 324

CP001891_3622: domain 1 of 1, from 663 to 730: score 59.2, E = 2.4e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +la+lsH+LRTPLt++ g ae+L +l + ++++
CP001891_3 663 LRNSLLAALSHDLRTPLTVLFGQAEILTLDL-------ASEGSKH-- 700

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + i++ + rL+n+lLd++ri++g
CP001891_3 701 ----------APQANEIRQHVLNTTRLVNNLLDMARIQSG 730

CP001891_0650: domain 1 of 1, from 236 to 302: score 56.3, E = 1.6e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++f+++++HELR PL+a++ +++++ + ++e r
CP001891_0 236 RERRFTSDAAHELRSPLAALKVQTDVAQL---------SMDDAEGR- 272

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l +++ ++r rL+++lL+lsr+++
CP001891_0 273 ----------EKALAQLHQGIDRATRLVDQLLTLSRLDSL 302

CP001891_0323: domain 1 of 1, from 233 to 293: score 53.8, E = 8.1e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ ++a++sH+LRTPLt Ir+++e++ e ++
CP001891_0 233 DRTLLMAGVSHDLRTPLTRIRLATEMMGE---------QD------- 263

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ e+i +++e ++++i+++ d+ r +++
CP001891_0 264 ----------GYLAESINKDIEECNAIIEQFIDYLRTGQE 293

CP001891_1531: domain 1 of 1, from 398 to 463: score 48.5, E = 2.6e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++f+ +++HE+RTPL++I++++e L+ +++s q
CP001891_1 398 HQRQFMGMVAHEFRTPLAVIQAALENLRL---------SAASTSQ-- 433

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +++i r+a rl +L ++ L +r+ +
CP001891_1 434 ----------EARFDRIGRAATRLVQLTDNCLADARLASH 463

CP001891_3540: domain 1 of 1, from 143 to 203: score 46.5, E = 9.9e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ + f+a+++HELRTPL+++r+++elL + +
CP001891_3 143 RERLFTADVAHELRTPLAGLRLHLELLAK----------VHGVGV-- 177

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +++ ++++ i++lL+l+r ++
CP001891_3 178 --------------DPLIQRLDQMTTSISQLLQLARVGQS 203

CP001891_2811: domain 1 of 1, from 211 to 271: score 44.0, E = 5e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+k +++ +++HELRTPL +r +e+ ++ l+e +
CP001891_2 211 SKKQLIDGIAHELRTPLVRLRYRLEMSEN-----------LTEAE-- 244

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + r++ +l++Li++lL+++r++ +
CP001891_2 245 -------------SQALNRDIGQLEALIEELLTYARLDRP 271

CP001891_2595: domain 1 of 1, from 170 to 233: score 43.4, E = 7.1e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +a ++HELR PLta +g ++ +l++++ ++s+eq
CP001891_2 170 LRTSHVA-MAHELRSPLTAAIGRLQGMLDGVF-------DASPEQ-- 206

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
l + +++++l+rL ++l ls +ag
CP001891_2 207 -------------LAMVMKQLQHLNRLTDELHLLSLSDAG 233

CP001891_4714: domain 1 of 1, from 402 to 464: score 41.0, E = 3.5e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a ++++ +l+H++++ L++I+g +el + ++++++
CP001891_4 402 AVGQLTGGLAHDFNNLLAVIIGSLELVEP---------DARDAPR-- 437

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
l+++l++aer L ++lL +sr +a
CP001891_4 438 -------------LSRALKAAERGALLTQRLLAFSRKQAL 464

CP001891_2471: domain 1 of 1, from 226 to 284: score 32.9, E = 6.7e-09
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ + la++sH+L TP+t +++ +e++
CP001891_2 226 ERARILAAISHDLQTPITRMKLRVEMADQ------------------ 254

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e+ +++l++++ + rL+++ ++r ++
CP001891_2 255 ----------PELRDKLLQDLDNMTRLVREGIAFARTSQP 284


Histogram of all scores:
score obs exp (one = represents 17 sequences)
----- --- ---
-15 3 0|=
-14 17 0|=
-13 56 3|*===
-12 180 115|======*====
-11 458 599|=========================== *
-10 850 1112|================================================== *
-9 978 1148|==========================================================*
-8 923 859|==================================================*====
-7 655 541|===============================*=======
-6 390 311|==================*====
-5 239 171|==========*====
-4 122 91|=====*==
-3 66 48|==*=
-2 37 25|=*=
-1 31 13|*=
0 12 6|*
1 6 3|*
2 5 1|*
3 3 0|=
> 4 26 -|==


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 280.4780
P(chi-square) = 0

Total sequences searched: 5057

Whole sequence top hits:
tophits_s report:
Total hits: 24
Satisfying E cutoff: 24
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 23
Satisfying E cutoff: 23
Total memory: 30K


Acknowledgements:

This research is funded by:

Developed by: