Acidobacteria Actinobacteria Alphaproteobacteria
Aquificae Bacteroidetes/Chlorobi Betaproteobacteria
Chlamydiae/Verrucomicrobia Chloroflexi Cyanobacteria
Deinococcus-Thermus Deltaproteobacteria Epsilonproteobacteria
Firmicutes Fusobacteria Gammaproteobacteria
Other Bacteria Planctomycetes Spirochaetes
Thermotogae
Classification of phyla is from NCBI page
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264 projects found  

3 accessions found for Enterobacter cloacae subsp. cloacae ATCC 13047  

Data for CP001918  

Available Atlases
Other Plots
hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: CP001918.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
CP001918_4084 CDS_4221879-4224638 98.7 1.5e-27 1
CP001918_1148 CDS_1189061-1190356 91.8 1.5e-25 1
CP001918_2785 CDS_2869533-2867374 80.7 2e-22 1
CP001918_3488 CDS_3610057-3607211 80.6 2.2e-22 1
CP001918_4551 CDS_4708365-4706032 78.9 6.3e-22 1
CP001918_3859 CDS_3984176-3982794 70.7 1.4e-19 1
CP001918_3371 CDS_3478460-3479863 69.1 3.9e-19 1
CP001918_5019 CDS_5203581-5204954 65.7 3.6e-18 1
CP001918_1942 CDS_1995836-1994379 62.9 2.1e-17 1
CP001918_4834 CDS_4985242-4983842 60.8 8.5e-17 1
CP001918_4408 CDS_4558045-4554857 59.4 2.1e-16 1
CP001918_5066 CDS_5252492-5253541 59.2 2.5e-16 1
CP001918_4854 CDS_5003669-5005150 59.2 2.5e-16 1
CP001918_2991 CDS_3073378-3076065 55.5 2.8e-15 1
CP001918_4305 CDS_4456855-4458192 55.3 3.2e-15 1
CP001918_2109 CDS_2177635-2176247 55.1 3.6e-15 1
CP001918_4727 CDS_4879971-4878634 54.9 4.1e-15 1
CP001918_4524 CDS_4685728-4686771 52.6 1.9e-14 1
CP001918_1752 CDS_1776902-1777969 45.4 2e-12 1
CP001918_4271 CDS_4418687-4416900 44.3 4.1e-12 1
CP001918_2251 CDS_2324771-2326069 43.1 8.8e-12 1
CP001918_2222 CDS_2292866-2294062 41.4 2.8e-11 1
CP001918_3504 CDS_3632184-3630775 36.8 5.5e-10 1
CP001918_0344 CDS_357115-359391 35.8 1.1e-09 2
CP001918_0713 CDS_709200-714782 35.0 1.7e-09 1
CP001918_1960 CDS_2014143-2012848 32.3 1e-08 1
CP001918_2328 CDS_2400637-2399309 32.2 1.1e-08 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CP001918_4084 1/1 292 357 .. 1 87 [] 98.7 1.5e-27
CP001918_1148 1/1 203 269 .. 1 87 [] 91.8 1.5e-25
CP001918_2785 1/1 497 565 .. 1 87 [] 80.7 2e-22
CP001918_3488 1/1 469 534 .. 1 87 [] 80.6 2.2e-22
CP001918_4551 1/1 282 347 .. 1 87 [] 78.9 6.3e-22
CP001918_3859 1/1 234 302 .. 1 87 [] 70.7 1.4e-19
CP001918_3371 1/1 240 304 .. 1 87 [] 69.1 3.9e-19
CP001918_5019 1/1 238 300 .. 1 87 [] 65.7 3.6e-18
CP001918_1942 1/1 261 327 .. 1 87 [] 62.9 2.1e-17
CP001918_4834 1/1 247 313 .. 1 87 [] 60.8 8.5e-17
CP001918_4408 1/1 572 638 .. 1 87 [] 59.4 2.1e-16
CP001918_5066 1/1 129 186 .. 1 79 [. 59.2 2.5e-16
CP001918_4854 1/1 262 328 .. 1 87 [] 59.2 2.5e-16
CP001918_2991 1/1 663 730 .. 1 87 [] 55.5 2.8e-15
CP001918_4305 1/1 232 298 .. 1 87 [] 55.3 3.2e-15
CP001918_2109 1/1 242 307 .. 1 87 [] 55.1 3.6e-15
CP001918_4727 1/1 230 290 .. 1 87 [] 54.9 4.1e-15
CP001918_4524 1/1 136 196 .. 1 87 [] 52.6 1.9e-14
CP001918_1752 1/1 136 199 .. 1 87 [] 45.4 2e-12
CP001918_4271 1/1 227 292 .. 1 87 [] 44.3 4.1e-12
CP001918_2251 1/1 211 271 .. 1 87 [] 43.1 8.8e-12
CP001918_2222 1/1 170 233 .. 1 87 [] 41.4 2.8e-11
CP001918_3504 1/1 246 311 .. 1 87 [] 36.8 5.5e-10
CP001918_0344 2/2 401 463 .. 1 87 [] 35.3 1.5e-09
CP001918_0713 1/1 1635 1705 .. 1 87 [] 35.0 1.7e-09
CP001918_1960 1/1 224 282 .. 1 87 [] 32.3 1e-08
CP001918_2328 1/1 219 280 .. 1 80 [. 32.2 1.1e-08

Alignments of top-scoring domains:
CP001918_4084: domain 1 of 1, from 292 to 357: score 98.7, E = 1.5e-27
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
kseflan+sHELRTPL++++g++ l l+ +el++ q
CP001918_4 292 IKSEFLANMSHELRTPLNGVIGFTRLTLK---------SELNPTQ-- 327

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+ l+ti+r+a+ ll++ind+Ld+s++eag
CP001918_4 328 ----------RDHLHTIERSANNLLAIINDVLDFSKLEAG 357

CP001918_1148: domain 1 of 1, from 203 to 269: score 91.8, E = 1.5e-25
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++ f+an+sHELRTPLt+++gy+e+++e ++l r
CP001918_1 203 ARRNFFANVSHELRTPLTVLQGYLEMMQE---------QTLEGAPR- 239

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l+t++++++r++ L+ +lL+ls+iea
CP001918_1 240 ----------EKALHTMREQTHRMEGLVKQLLTLSKIEAA 269

CP001918_2785: domain 1 of 1, from 497 to 565: score 80.7, E = 2e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++ef+an+sH+LRTPLt+++gy+e+L ++ ++l+++++
CP001918_2 497 QRREFIANISHDLRTPLTSLLGYLETLSLKS-------ATLTPQEH- 535

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++yl t+lr+++ ++L ++l +l+r+e+g
CP001918_2 536 ----------QQYLATALRQGQKVRHLSQQLFELARLEHG 565

CP001918_3488: domain 1 of 1, from 469 to 534: score 80.6, E = 2.2e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ks fla++sHELRTPL +I+g+++lL++ el+
CP001918_3 469 SKSMFLATVSHELRTPLYGIIGNLDLLQT---------KELPKGV-- 504

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ + +++ ll++i+d+Ld+s+ie++
CP001918_3 505 ----------DRLVTAMNNSSSLLLKIISDILDFSKIESE 534

CP001918_4551: domain 1 of 1, from 282 to 347: score 78.9, E = 6.3e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k+ f++++sHELRTPL++I g++ +Ll+ t+l++eq
CP001918_4 282 DKTTFISTISHELRTPLNGIVGLSRILLD---------TDLTAEQ-- 317

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++yl+ti+ +a l ++ nd+ d+ ++e
CP001918_4 318 ----------EKYLKTIHVSAVTLGNIFNDIIDMDKMERR 347

CP001918_3859: domain 1 of 1, from 234 to 302: score 70.7, E = 1.4e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +fl+++sHEL+TPL+++r +elL +e+ ++l+ eq
CP001918_3 234 QRHQFLRHISHELKTPLASMREGTELLADEVA------GPLTVEQ-- 272

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e++e+++ +++ l++Li++lLd+ r a
CP001918_3 273 ----------KEIVEILDASSRNLQKLIEQLLDYNRKLAD 302

CP001918_3371: domain 1 of 1, from 240 to 304: score 69.1, E = 3.9e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+a++sHELRTPL+++rg +e++++++ + ++e
CP001918_3 240 MRRDFMADISHELRTPLAVLRGELEAIQDGV-------RKFTPES-- 277

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +++ e+ l +L++dl +ls ++g
CP001918_3 278 -------------VASLQAEVGTLTKLVDDLHQLSMSDEG 304

CP001918_5019: domain 1 of 1, from 238 to 300: score 65.7, E = 3.6e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++l+++sHELRTPLt +++ + lL++ +++
CP001918_5 238 TQQRLLSDISHELRTPLTRLQLGTALLRR---------RSGESKE-- 273

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
le+i+ ea+rl+++indlL +sr ++
CP001918_5 274 -------------LERIETEAQRLDSMINDLLVMSRNQQK 300

CP001918_1942: domain 1 of 1, from 261 to 327: score 62.9, E = 2.1e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ f a+++HE+RTP+t + + +e++l +++s++++
CP001918_1 261 RQANFSADIAHEIRTPITNLVTQTEIALS---------QNRSPKEL- 297

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ l + l+e +r+ r+++d+L l++++++
CP001918_1 298 ----------EDVLYSSLEEYNRMTRMVSDMLFLAQADNN 327

CP001918_4834: domain 1 of 1, from 247 to 313: score 60.8, E = 8.5e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+s+f ++++HELRTP++ +++ ++ +l+ e++ +
CP001918_4 247 KLSDFSSDIAHELRTPVSNLMMQTQFALA---------KERDVSH-- 282

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
yre+l l+e++rl+r+ +d+L l+r e+g
CP001918_4 283 ---------YREILFANLEELKRLSRMTSDMLFLARSEHG 313

CP001918_4408: domain 1 of 1, from 572 to 638: score 59.4, E = 2.1e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
ks fla++sHE+RTP++aI+g++el + + ++q+
CP001918_4 572 GKSAFLATMSHEIRTPVSAIIGMLELVMK---------RPDHAPQN- 608

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ ++++ ++a++ll Li ++Ld +ri +g
CP001918_4 609 ----------PQSIRVAWDAAQSLLLLIGNILDVERIASG 638

CP001918_5066: domain 1 of 1, from 129 to 186: score 59.2, E = 2.5e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a ++++++l+HE+++PL ++rg+a+lL + +l+++ +
CP001918_5 129 AARDLVRGLAHEIKNPLGGLRGAAQLLTK----------ALPDPAL- 164

peLRledpeyreyletilreaerllrLindlL<-*
+ey+++i+++a+rl++L+++lL
CP001918_5 165 ----------AEYTNVIIEQADRLRNLVDRLL 186

CP001918_4854: domain 1 of 1, from 262 to 328: score 59.2, E = 2.5e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ f a+++HE+RTP+t + + +e++l ++++ ++
CP001918_4 262 RQANFSADIAHEIRTPITNLVTQTEIALS---------QDRTQREL- 298

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ l + l+e +r+ ++++d+L l++++++
CP001918_4 299 ----------EDVLYSSLEEYNRMTKMVSDMLFLAQADNN 328

CP001918_2991: domain 1 of 1, from 663 to 730: score 55.5, E = 2.8e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +la+lsH+LRTPLt++ g +e+L +l ++ ++++
CP001918_2 663 IRNSLLAALSHDLRTPLTVLFGQSEILTLDL-------AAEGSKH-- 700

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + i++ + rL+n+lLd++ri++g
CP001918_2 701 ----------ALQASEIRQHVLNTTRLVNNLLDMARIQSG 730

CP001918_4305: domain 1 of 1, from 232 to 298: score 55.3, E = 3.2e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++f+++++HELR PL+a++ +++++ l+++q++
CP001918_4 232 RERRFTSDAAHELRSPLAALKVQTDVAQL----------SLDDPQAQ 268

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l+ ++ ++r +rL+++lL+lsr+++
CP001918_4 269 ----------EKALSQLHAGIDRASRLVDQLLTLSRLDSL 298

CP001918_2109: domain 1 of 1, from 242 to 307: score 55.1, E = 3.6e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ + f+a+++HELRTPL+a+r ++e+L++++ s+ q
CP001918_2 242 RERVFIADAAHELRTPLAAMRINVEALQAYV---------SSDNQ-- 277

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +l i+r+ r rL+n+lL + ea
CP001918_2 278 ----------QALLAGIIRSNSRAARLVNQLLLMMHSEAS 307

CP001918_4727: domain 1 of 1, from 230 to 290: score 54.9, E = 4.1e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ ++a++sH+LRTPLt Ir+++e++ e e+
CP001918_4 230 DRTLLMAGVSHDLRTPLTRIRLATEMMGE--------------ED-- 260

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ e+i +++e ++++i+++ d+ r +++
CP001918_4 261 ----------GYLAESINKDIEECNAIIEQFIDYLRTGQE 290

CP001918_4524: domain 1 of 1, from 136 to 196: score 52.6, E = 1.9e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ + f+a+++HELRTPL++Ir+++el+ +
CP001918_4 136 QERLFTADAAHELRTPLAGIRLHLELMAQSG---------------- 166

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +++ +++l + i++lL l+r+++
CP001918_4 167 ----------SPQASALISRIDQLMHTIEQLLMLARAGQA 196

CP001918_1752: domain 1 of 1, from 136 to 199: score 45.4, E = 2e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ + a+++HELRTP+t +rg ++ L + + ++e
CP001918_1 136 QRKSWNAAIAHELRTPVTILRGRLQGLVD---------GVFTPEP-- 171

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ +l+++e l rLi+d L + g
CP001918_1 172 -----------VLFNNLLKQTEGLARLIED-LRVVSSDGG 199

CP001918_4271: domain 1 of 1, from 227 to 292: score 44.3, E = 4.1e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k++fl ++sH+LR+P++a+ +++e++ ++++
CP001918_4 227 DKNQFLTTASHDLRQPVHAMGFLIEAIIH---------RNRDDSL-- 262

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
l +++++++ + n lLdls+ie+g
CP001918_4 263 ----------TPQLLDLQQSVRSVHLMFNSLLDLSKIESG 292

CP001918_2251: domain 1 of 1, from 211 to 271: score 43.1, E = 8.8e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+k +++ +++HELRTPL +r +e+ ++ l++ +
CP001918_2 211 SKKQLIDGIAHELRTPLVRLRYRLEMSEN-----------LTAAE-- 244

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + r++ +l++Li++lL+++r++ +
CP001918_2 245 -------------SQALNRDIGQLEALIEELLTYARLDRP 271

CP001918_2222: domain 1 of 1, from 170 to 233: score 41.4, E = 2.8e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ +a ++HELR PLta +g ++ + ++++ ++++eq
CP001918_2 170 LRASHVA-MAHELRSPLTAAIGRLQGMMDGVF-------DATPEQ-- 206

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
l + +++++l+rL ++l ls ++ag
CP001918_2 207 -------------LGMVMKQLQHLNRLTDELHLLSLADAG 233

CP001918_3504: domain 1 of 1, from 246 to 311: score 36.8, E = 5.5e-10
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f a++sH+L+TPL+++++ ++++l+ ++++ +
CP001918_3 246 RQERFNADASHQLKTPLAVLKTQVSVALT-----------RNDPAL- 280

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++e l+ + ++ L ++lL+ls +
CP001918_3 281 ---------WQESLRAMNVTLDNTIVLTERLLQLSTVRRK 311

CP001918_0344: domain 2 of 2, from 401 to 463: score 35.3, E = 1.5e-09
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a ++++ +l+H++++ L++I+g +el + +++
CP001918_0 401 AVGQLTGGLAHDFNNLLAVIIGSLELTDP---------DSSDAPR-- 436

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ ++l++aer L ++lL +sr ++
CP001918_0 437 -------------IARALNAAERGALLTQRLLAFSRKQSL 463

CP001918_0713: domain 1 of 1, from 1635 to 1705: score 35.0, E = 1.7e-09
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++++++HE+++PL +I +a + l++l+ +++++ ++
CP001918_0 1635 TVGQLTSSIAHEINQPLMSIVSNAGASLRWLN----REPARLDKV-- 1675

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
re le i e+ r ++i+ + l+r + +
CP001918_0 1676 ----------REGLEEIAAEGARAGEIIRSIQSLTRKQDP 1705

CP001918_1960: domain 1 of 1, from 224 to 282: score 32.3, E = 1e-08
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ + la++sH+L TP+t +++ +e++
CP001918_1 224 ERAQILASVSHDLQTPITRMKLRVEMADQ------------------ 252

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e+ +++l++++ + rL+++ ++r +
CP001918_1 253 ----------PELRDKLLNDLDNMTRLVREGIAYARSSES 282

CP001918_2328: domain 1 of 1, from 219 to 280: score 32.2, E = 1.1e-08
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++e +a++ HE+++PLta+++ ++ ++++l + + + +
CP001918_2 219 TLGEITAGIVHEINQPLTAVQTWIQGAQRQL-------QQENGQAV- 257

peLRledpeyreyletilreaerllrLindlLd<-*
++l+ +l +++r+++L+ ++++
CP001918_2 258 ----------SQALSAALTQTQRISALLTRFRE 280


Histogram of all scores:
score obs exp (one = represents 17 sequences)
----- --- ---
-15 3 0|=
-14 36 0|===
-13 86 3|*=====
-12 279 117|======*==========
-11 519 606|=============================== *
-10 897 1125|===================================================== *
-9 948 1162|======================================================== *
-8 865 870|===================================================*
-7 616 548|================================*====
-6 357 315|==================*==
-5 193 173|==========*=
-4 136 92|=====*==
-3 54 48|==*=
-2 33 25|=*
-1 33 13|*=
0 22 7|*=
1 6 3|*
2 4 1|*
3 3 0|=
> 4 30 -|==


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 422.5517
P(chi-square) = 0

Total sequences searched: 5120

Whole sequence top hits:
tophits_s report:
Total hits: 27
Satisfying E cutoff: 27
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 27
Satisfying E cutoff: 27
Total memory: 31K


Acknowledgements:

This research is funded by:

Developed by: