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Classification of phyla is from NCBI page
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106 projects found  

2 accessions found for Tsukamurella paurometabola DSM 20162  

Data for CP001966  

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hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
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HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: CP001966.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
CP001966_3178 CDS_3348963-3351524 75.5 4.7e-21 1
CP001966_0636 CDS_670529-671722 72.0 4.6e-20 1
CP001966_1055 CDS_1101246-1102910 69.2 2.9e-19 1
CP001966_3554 CDS_3746246-3744840 65.7 2.8e-18 1
CP001966_3216 CDS_3382744-3381308 62.0 3.2e-17 1
CP001966_0094 CDS_99157-100284 61.7 4e-17 1
CP001966_1974 CDS_2102404-2103546 60.6 8.2e-17 1
CP001966_0098 CDS_104035-105387 49.3 1.3e-13 1
CP001966_1590 CDS_1698156-1699214 42.2 1.3e-11 1
CP001966_0508 CDS_550453-551580 37.3 3.3e-10 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CP001966_3178 1/1 621 689 .. 1 87 [] 75.5 4.7e-21
CP001966_0636 1/1 152 218 .. 1 87 [] 72.0 4.6e-20
CP001966_1055 1/1 304 371 .. 1 87 [] 69.2 2.9e-19
CP001966_3554 1/1 247 311 .. 1 87 [] 65.7 2.8e-18
CP001966_3216 1/1 233 305 .. 1 87 [] 62.0 3.2e-17
CP001966_0094 1/1 152 216 .. 1 87 [] 61.7 4e-17
CP001966_1974 1/1 154 218 .. 1 87 [] 60.6 8.2e-17
CP001966_0098 1/1 226 299 .. 1 87 [] 49.3 1.3e-13
CP001966_1590 1/1 140 205 .. 1 87 [] 42.2 1.3e-11
CP001966_0508 1/1 153 217 .. 1 87 [] 37.3 3.3e-10

Alignments of top-scoring domains:
CP001966_3178: domain 1 of 1, from 621 to 689: score 75.5, E = 4.7e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++ +l+++sH+LRTPL++I++++ L+ d e+see+
CP001966_3 621 ARTALLSAVSHDLRTPLAGIKAAVTSLRS-------DDVEWSEEDE- 659

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e+leti+++a+rl++L+ +lLd+sr+e+
CP001966_3 660 ----------AELLETIEESADRLDSLVGNLLDMSRLESD 689

CP001966_0636: domain 1 of 1, from 152 to 218: score 72.0, E = 4.6e-20
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++f+an+sHEL+TP+ aI ++ae+Lle ++ ++e +
CP001966_0 152 TRRDFVANVSHELKTPVGAIGLLAEALLE---------SDDDPEAV- 188

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r + +++l+e+ r+ +++n+l lsr++
CP001966_0 189 ----------RHFGSRVLSESTRMGNMVNELIALSRLQGA 218

CP001966_1055: domain 1 of 1, from 304 to 371: score 69.2, E = 2.9e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++f++++sHELRTPLt++r++a+++ + + +el++
CP001966_1 304 LQRQFTSDVSHELRTPLTTVRMAADMIADSA-------DELDPGL-- 341

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+ +e + e++r + L+ +lL++sr +ag
CP001966_1 342 ----------RRTTELMVTELDRFELLLAELLEISRHDAG 371

CP001966_3554: domain 1 of 1, from 247 to 311: score 65.7, E = 2.8e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+ ++sHELRTPLt+Irg+ael + +s +
CP001966_3 247 RMRRFVGDASHELRTPLTSIRGFAELYRQ----------GASGDI-- 281

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ i++ea+r+ L++dlL l+r++a
CP001966_3 282 ----------DFLMCHIESEAQRMGLLVEDLLLLARLDAR 311

CP001966_3216: domain 1 of 1, from 233 to 305: score 62.0, E = 3.2e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkv.lagdtelseeqr
++s+++a++ HELRTPLt++r+++elL + + +g ++ +ee++
CP001966_3 233 RQSRLVADAGHELRTPLTSLRTNVELLIA----AnRPGAPAIPEEDV 275

lpeLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e+ + ++ ++e l L+ dl dl+r +a+
CP001966_3 276 -----------QELSDDVIAQVEELTTLVGDLVDLAREDAP 305

CP001966_0094: domain 1 of 1, from 152 to 216: score 61.7, E = 4e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++++l +l+HE+RTP++++ gy+e +++ + s+++
CP001966_0 152 SRRRLLTDLAHEIRTPVSVLDGYLEGMQD---------GVVSADE-- 187

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e + ++++++rl rL +d+L s +++g
CP001966_0 188 -----------ETVTMLREQTNRLARLTEDVLAVSHADEG 216

CP001966_1974: domain 1 of 1, from 154 to 218: score 60.6, E = 8.2e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+++f+a +sH+LRTPLt+Ir++ae+L e ++++r
CP001966_1 154 ARGQFFAWISHDLRTPLTGIRALAEALDE-----------GTAPDR- 188

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ yl ++ ++ l+ +i dl +ls +++g
CP001966_1 189 ----------AAYLTALRGKVDTLNGMITDLFELSTMQSG 218

CP001966_0098: domain 1 of 1, from 226 to 299: score 49.3, E = 1.3e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++f++++sHELR PL+a+ +ae+L+ee+d + + e
CP001966_0 226 RSRRFASDVSHELRSPLAALVPAAEVLREEAD------AMAAESSGH 266

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
p L +++ + + +e++ l +L++dlL+++r++ag
CP001966_0 267 PDL-------ARAARMVASEVDGLAQLLDDLLEITRLDAG 299

CP001966_1590: domain 1 of 1, from 140 to 205: score 42.2, E = 1.3e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+a+++HELR P+ a+r+ +e++ + ++r+
CP001966_1 140 RQRRFVADAAHELRGPIGAVRTDLEVAAR-------------YPDRI 173

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ + +l+ +l ++erl+ dlL+l+r+e+g
CP001966_1 174 DA--------AGALNEALVDVERLQTVATDLLTLARLESG 205

CP001966_0508: domain 1 of 1, from 153 to 217: score 37.3, E = 3.3e-10
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+an+sHELRTPL+ ++++++++ d+e++++++
CP001966_0 153 EQQRFAANASHELRTPLAITQTLLDVARS--------DPERDDDEL- 190

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++++ r +L + lL lsr++
CP001966_0 191 -------------VSRLQFVNARAIDLTEALLLLSRADRR 217


Histogram of all scores:
score obs exp (one = represents 16 sequences)
----- --- ---
-15 1 0|=
-14 7 0|=
-13 42 3|*==
-12 172 95|=====*=====
-11 423 492|=========================== *
-10 689 914|============================================ *
-9 894 944|======================================================== *
-8 760 706|============================================*===
-7 506 445|===========================*====
-6 290 256|===============*===
-5 169 140|========*==
-4 89 75|====*=
-3 46 39|==*
-2 28 20|=*
-1 15 10|*
0 8 5|*
1 2 2|*
2 1 1|*
3 1 0|=
4 1 0|=
> 5 13 -|=


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 161.1655
P(chi-square) = 3.04e-28

Total sequences searched: 4157

Whole sequence top hits:
tophits_s report:
Total hits: 10
Satisfying E cutoff: 10
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 10
Satisfying E cutoff: 10
Total memory: 24K


Acknowledgements:

This research is funded by:

Developed by: