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Classification of phyla is from NCBI page
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264 projects found  

1 accessions found for Escherichia coli IHE3034  

Data for CP001969  

Available Atlases
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hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: CP001969.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
CP001969_3026 CDS_3222566-3225322 100.1 5.8e-28 1
CP001969_0364 CDS_421431-422726 91.0 2.3e-25 1
CP001969_2573 CDS_2760876-2764469 81.6 1e-22 1
CP001969_1005 CDS_1087527-1084825 80.7 1.8e-22 1
CP001969_2347 CDS_2534350-2531501 80.6 2e-22 1
CP001969_3485 CDS_3725780-3723444 78.9 6.1e-22 1
CP001969_2348 CDS_2534517-2536343 77.9 1.1e-21 1
CP001969_2779 CDS_2987733-2986351 75.4 6e-21 1
CP001969_2206 CDS_2378428-2379831 70.4 1.5e-19 1
CP001969_4199 CDS_4494059-4492686 66.6 1.8e-18 1
CP001969_4754 CDS_5103427-5104851 62.4 2.8e-17 1
CP001969_4288 CDS_4602456-4603832 61.5 5.1e-17 1
CP001969_0561 CDS_617025-615583 61.0 7.1e-17 1
CP001969_3305 CDS_3540905-3542254 60.7 8.9e-17 1
CP001969_4161 CDS_4454528-4453479 59.7 1.7e-16 1
CP001969_0677 CDS_743088-740404 59.6 1.7e-16 1
CP001969_3666 CDS_3901435-3900083 55.0 3.5e-15 1
CP001969_2004 CDS_2100420-2099062 52.3 2e-14 1
CP001969_4427 CDS_4759298-4758207 45.0 2.4e-12 1
CP001969_1658 CDS_1759858-1761159 42.4 1.4e-11 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CP001969_3026 1/1 292 357 .. 1 87 [] 100.1 5.8e-28
CP001969_0364 1/1 203 269 .. 1 87 [] 91.0 2.3e-25
CP001969_2573 1/1 711 777 .. 1 87 [] 81.6 1e-22
CP001969_1005 1/1 433 498 .. 1 87 [] 80.7 1.8e-22
CP001969_2347 1/1 469 534 .. 1 87 [] 80.6 2e-22
CP001969_3485 1/1 282 347 .. 1 87 [] 78.9 6.1e-22
CP001969_2348 1/1 388 453 .. 1 87 [] 77.9 1.1e-21
CP001969_2779 1/1 234 302 .. 1 87 [] 75.4 6e-21
CP001969_2206 1/1 240 304 .. 1 87 [] 70.4 1.5e-19
CP001969_4199 1/1 238 300 .. 1 87 [] 66.6 1.8e-18
CP001969_4754 1/1 255 320 .. 1 87 [] 62.4 2.8e-17
CP001969_4288 1/1 237 303 .. 1 87 [] 61.5 5.1e-17
CP001969_0561 1/1 261 327 .. 1 87 [] 61.0 7.1e-17
CP001969_3305 1/1 236 302 .. 1 87 [] 60.7 8.9e-17
CP001969_4161 1/1 129 186 .. 1 79 [. 59.7 1.7e-16
CP001969_0677 1/1 663 730 .. 1 87 [] 59.6 1.7e-16
CP001969_3666 1/1 233 293 .. 1 87 [] 55.0 3.5e-15
CP001969_2004 1/1 235 301 .. 1 87 [] 52.3 2e-14
CP001969_4427 1/1 142 202 .. 1 87 [] 45.0 2.4e-12
CP001969_1658 1/1 211 271 .. 1 87 [] 42.4 1.4e-11

Alignments of top-scoring domains:
CP001969_3026: domain 1 of 1, from 292 to 357: score 100.1, E = 5.8e-28
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
kseflan+sHELRTPL++++g++ l l+ tel++ q
CP001969_3 292 IKSEFLANMSHELRTPLNGVIGFTRLTLK---------TELTPTQ-- 327

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+ l+ti+r+a+ ll++ind+Ld+s++eag
CP001969_3 328 ----------RDHLNTIERSANNLLAIINDVLDFSKLEAG 357

CP001969_0364: domain 1 of 1, from 203 to 269: score 91.0, E = 2.3e-25
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++ f+an+sHELRTPLt+++gy+e++ e ++l r
CP001969_0 203 ARRNFFANVSHELRTPLTVLQGYLEMMDE---------QPLEGAVR- 239

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l+t++++++r++ L+ +lL+ls+iea
CP001969_0 240 ----------EKALHTMREQTQRMEGLVKQLLTLSKIEAA 269

CP001969_2573: domain 1 of 1, from 711 to 777: score 81.6, E = 1e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks+fla++sHE+RTP+++I+g++elL + ls eqr
CP001969_2 711 AKSQFLATMSHEIRTPISSIMGFLELLSG---------SGLSKEQR- 747

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e+++ ++ +++ll Li ++Ld +ie+g
CP001969_2 748 ----------VEAISLAYATGQSLLGLIGEILDVDKIESG 777

CP001969_1005: domain 1 of 1, from 433 to 498: score 80.7, E = 1.8e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks fla++sHE+RTPL +I+g+a+lL + ++ q
CP001969_1 433 AKSAFLAAMSHEIRTPLYGILGTAQLLAD---------NPALNAQ-- 468

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+ l+ i +++e+ll ++nd+Ld+s ieag
CP001969_1 469 ----------RDDLRAITDSGESLLTILNDILDYSAIEAG 498

CP001969_2347: domain 1 of 1, from 469 to 534: score 80.6, E = 2e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ks fla++sHELRTPL +I+g+++lL++ el+
CP001969_2 469 SKSMFLATVSHELRTPLYGIIGNLDLLQT---------KELPKGV-- 504

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ + +++ ll++i+d+Ld+s+ie++
CP001969_2 505 ----------DRLVTAMNNSSSLLLKIISDILDFSKIESE 534

CP001969_3485: domain 1 of 1, from 282 to 347: score 78.9, E = 6.1e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k+ f++++sHELRTPL++I g++ +Ll+ tel++eq
CP001969_3 282 DKTTFISTISHELRTPLNGIVGLSRILLD---------TELTAEQ-- 317

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++yl+ti+ +a l ++ nd+ d+ ++e
CP001969_3 318 ----------EKYLKTIHVSAVTLGNIFNDIIDMDKMERR 347

CP001969_2348: domain 1 of 1, from 388 to 453: score 77.9, E = 1.1e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++e++a+++HE R+PLtaIrgy+++L+ +++++ +
CP001969_2 388 TLGELMAGVAHEVRNPLTAIRGYVQILRQ---------QTRDPIH-- 423

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+eyl+++l+e++++++ i++lL++sr ++
CP001969_2 424 ----------QEYLSVVLKEIDSINKVIQQLLEFSRPRHS 453

CP001969_2779: domain 1 of 1, from 234 to 302: score 75.4, E = 6e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +fl++lsHEL+TPL+++r +elL +++ ++l++eq
CP001969_2 234 QRHQFLRHLSHELKTPLASMREGTELLADQV------VGPLTPEQ-- 272

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e +++++++++ l++Li++lLd+ r +a
CP001969_2 273 ----------KEVVSILDSSSRNLQKLIEQLLDYNRKQAD 302

CP001969_2206: domain 1 of 1, from 240 to 304: score 70.4, E = 1.5e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+a++sHELRTPL+++rg +e++++++ + ++e+
CP001969_2 240 MRRDFMADISHELRTPLAVLRGELEAIQDGV-------RKFTPET-- 277

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
l +++ e+ l +L++dl +ls ++g
CP001969_2 278 -------------LASLQAEVGTLTKLVDDLHQLSMSDEG 304

CP001969_4199: domain 1 of 1, from 238 to 300: score 66.6, E = 1.8e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++++l+++sHELRTPLt +++ + lL++ +++
CP001969_4 238 SQQRLLSDISHELRTPLTRLQLGTALLRR---------RSGESKE-- 273

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
le+i+ ea+rl+++indlL +sr ++
CP001969_4 274 -------------LERIETEAQRLDSMINDLLVMSRNQQK 300

CP001969_4754: domain 1 of 1, from 255 to 320: score 62.4, E = 2.8e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ + +l HEL+ PL+aIrg+ae+L+e ++ +e
CP001969_4 255 YIEQYVYALTHELKSPLAAIRGAAEILRE---------GPPPEVV-- 290

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++++ il + r+++L++ lL +r+e+
CP001969_4 291 ----------ARFTDNILTQNARMQALVETLLRQARLENR 320

CP001969_4288: domain 1 of 1, from 237 to 303: score 61.5, E = 5.1e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++ ++a+++HE+R+PL++I+g+a+ e +++++ e
CP001969_4 237 ALGHLAAGVAHEIRNPLSSIKGLAKYFAE--------RAPAGGEA-- 273

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ +++ +ea+rl+r +++lL+l + +
CP001969_4 274 ----------HQLAQVMAKEADRLNRVVSELLELVKPTHL 303

CP001969_0561: domain 1 of 1, from 261 to 327: score 61.0, E = 7.1e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++s f a+++HE+RTP+t +++ +e++l + +s +++
CP001969_0 261 RQSNFSADIAHEIRTPITNLITQTEIALS---------QSRSQKEL- 297

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ l + l+e+ r+ ++++d+L l++++++
CP001969_0 298 ----------EDVLYSNLEELTRMAKMVSDMLFLAQADNN 327

CP001969_3305: domain 1 of 1, from 236 to 302: score 60.7, E = 8.9e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++f+++++HELR PLta++ +e+++ ++ +++ r
CP001969_3 236 RERRFTSDAAHELRSPLTALKVQTEVAQL---------SDDDPQAR- 272

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l +++ ++r rL+++lL+lsr+++
CP001969_3 273 ----------KKALLQLHSGIDRATRLVDQLLTLSRLDSL 302

CP001969_4161: domain 1 of 1, from 129 to 186: score 59.7, E = 1.7e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a ++++++l+HE+++PL ++rg+a+lL + +l+++ +
CP001969_4 129 AARDLVRGLAHEIKNPLGGLRGAAQLLSK----------ALPDPSL- 164

peLRledpeyreyletilreaerllrLindlL<-*
ey+++i+++a+rl++L+++lL
CP001969_4 165 ----------LEYTKVIIEQADRLRNLVDRLL 186

CP001969_0677: domain 1 of 1, from 663 to 730: score 59.6, E = 1.7e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +la+lsH+LRTPLt++ g ae+L +l + ++++
CP001969_0 663 IRNALLAALSHDLRTPLTVLFGQAEILTLDL-------ASEGSPH-- 700

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ + i++ + rL+n+lLd++ri++g
CP001969_0 701 ----------ARQASEIRQHVLNTTRLVNNLLDMARIQSG 730

CP001969_3666: domain 1 of 1, from 233 to 293: score 55.0, E = 3.5e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ ++a++sH+LRTPLt Ir+++e++ e ++
CP001969_3 233 DRTLLMAGVSHDLRTPLTRIRLATEMMSE---------QD------- 263

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ e+i +++e ++++i+++ d+ r +++
CP001969_3 264 ----------GYLAESINKDIEECNAIIEQFIDYLRTGQE 293

CP001969_2004: domain 1 of 1, from 235 to 301: score 52.3, E = 2e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++s+f+ +l+HELRTP++a++g ++ l +++s +
CP001969_2 235 RLSQFADDLAHELRTPINALLGQNQVTLS---------QTRSIAE-- 270

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
y++ + ++e+e ++rL +++L l+r++ +
CP001969_2 271 ---------YQKTIAGNIEELENISRLTENILFLARADKN 301

CP001969_4427: domain 1 of 1, from 142 to 202: score 45.0, E = 2.4e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ f+a+++HELRTPL+++r+++elL + t+
CP001969_4 142 NERLFTADVAHELRTPLAGVRLHLELLAK---------TH------- 172

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + + ++++ + +++lL+l+r+++
CP001969_4 173 ----------HIDVAPLVARLDQMMESVSQLLQLARAGQS 202

CP001969_1658: domain 1 of 1, from 211 to 271: score 42.4, E = 1.4e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+k +++ +++HELRTPL +r +e+ + ls+ +
CP001969_1 211 SKKQLIDGIAHELRTPLVRLRYRLEMSDN-----------LSAAE-- 244

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + r++ +l++Li++lL+++r++ +
CP001969_1 245 -------------SQALNRDISQLEALIEELLTYARLDRP 271


Histogram of all scores:
score obs exp (one = represents 15 sequences)
----- --- ---
-16 1 0|=
-15 4 0|=
-14 45 0|===
-13 95 3|*======
-12 246 108|=======*=========
-11 492 563|================================= *
-10 837 1046|======================================================== *
-9 884 1080|==========================================================*
-8 751 808|=================================================== *
-7 565 509|=================================*====
-6 349 293|===================*====
-5 206 160|==========*===
-4 104 86|=====*=
-3 59 45|==*=
-2 31 23|=*=
-1 34 12|*==
0 18 6|*=
1 6 3|*
2 6 1|*
3 1 0|=
4 0 0|
> 5 23 -|==


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 360.5240
P(chi-square) = 0

Total sequences searched: 4757

Whole sequence top hits:
tophits_s report:
Total hits: 20
Satisfying E cutoff: 20
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 20
Satisfying E cutoff: 20
Total memory: 28K


Acknowledgements:

This research is funded by:

Developed by: