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1 accessions found for Methanohalophilus mahii DSM 5219  

Data for CP001994  

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hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
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HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: CP001994.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
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Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
CP001994_1461 CDS_1500835-1498637 105.6 7e-30 1
CP001994_0279 CDS_308372-306495 98.6 6.6e-28 1
CP001994_0424 CDS_451549-454653 96.5 2.6e-27 1
CP001994_0421 CDS_449307-446926 95.8 4e-27 1
CP001994_0895 CDS_932005-934215 94.4 9.8e-27 1
CP001994_1516 CDS_1556877-1553551 92.4 3.8e-26 1
CP001994_1953 CDS_1970817-1972715 92.3 4e-26 1
CP001994_1355 CDS_1396451-1398640 90.9 9.8e-26 1
CP001994_0806 CDS_842954-841227 88.0 6.5e-25 1
CP001994_0108 CDS_138275-136476 87.8 7.6e-25 1
CP001994_0581 CDS_618963-616822 84.0 9e-24 1
CP001994_0191 CDS_222465-224330 80.9 7e-23 1
CP001994_1036 CDS_1091388-1093301 69.5 1.1e-19 1
CP001994_1215 CDS_1262334-1263998 64.3 3.5e-18 1
CP001994_0816 CDS_853265-850377 60.9 3.2e-17 1
CP001994_1905 CDS_1919216-1920682 43.8 2.3e-12 1
CP001994_0596 CDS_635178-633646 38.9 5.4e-11 1
CP001994_0337 CDS_362805-361693 38.4 7.4e-11 1
CP001994_1216 CDS_1266809-1264008 35.7 4.2e-10 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CP001994_1461 1/1 505 573 .. 1 87 [] 105.6 7e-30
CP001994_0279 1/1 396 464 .. 1 87 [] 98.6 6.6e-28
CP001994_0424 1/1 811 879 .. 1 87 [] 96.5 2.6e-27
CP001994_0421 1/1 556 624 .. 1 87 [] 95.8 4e-27
CP001994_0895 1/1 511 579 .. 1 87 [] 94.4 9.8e-27
CP001994_1516 1/1 863 931 .. 1 87 [] 92.4 3.8e-26
CP001994_1953 1/1 404 472 .. 1 87 [] 92.3 4e-26
CP001994_1355 1/1 501 569 .. 1 87 [] 90.9 9.8e-26
CP001994_0806 1/1 350 416 .. 1 87 [] 88.0 6.5e-25
CP001994_0108 1/1 370 438 .. 1 87 [] 87.8 7.6e-25
CP001994_0581 1/1 483 551 .. 1 87 [] 84.0 9e-24
CP001994_0191 1/1 390 458 .. 1 87 [] 80.9 7e-23
CP001994_1036 1/1 405 473 .. 1 87 [] 69.5 1.1e-19
CP001994_1215 1/1 329 397 .. 1 87 [] 64.3 3.5e-18
CP001994_0816 1/1 735 803 .. 1 87 [] 60.9 3.2e-17
CP001994_1905 1/1 274 341 .. 1 87 [] 43.8 2.3e-12
CP001994_0596 1/1 270 327 .. 1 76 [. 38.9 5.4e-11
CP001994_0337 1/1 152 217 .. 1 87 [] 38.4 7.4e-11
CP001994_1216 1/1 714 779 .. 1 87 [] 35.7 4.2e-10

Alignments of top-scoring domains:
CP001994_1461: domain 1 of 1, from 505 to 573: score 105.6, E = 7e-30
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
ks+flan+sHELRTPL++I+g++++Llee++ ++l+e+q
CP001994_1 505 TKSQFLANMSHELRTPLNSIIGFSDVLLEEAF------GKLNEKQ-- 543

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++y++ i ++++ll++ind+Ldls+ieag
CP001994_1 544 ----------KKYTHNINTSGHHLLDIINDILDLSKIEAG 573

CP001994_0279: domain 1 of 1, from 396 to 464: score 98.6, E = 6.6e-28
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
kseflan+sHELRTPL++++g++++L +e+ +++l++ q
CP001994_0 396 TKSEFLANMSHELRTPLNSVIGFSDILSKEV------RGKLNDSQ-- 434

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++y++ i +++ +ll+Lind+Ldls+ieag
CP001994_0 435 ----------KKYVSNITKSGSHLLSLINDILDLSKIEAG 464

CP001994_0424: domain 1 of 1, from 811 to 879: score 96.5, E = 2.6e-27
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
ks+flan+sHELRTPL++++g++++Ll+ + +el++ q
CP001994_0 811 TKSQFLANMSHELRTPLNSVIGFSDILLK------EIKGELNDSQ-- 849

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++y++ i + +++ll+Lind+Ldls+ieag
CP001994_0 850 ----------KKYISNISNGGRHLLDLINDILDLSKIEAG 879

CP001994_0421: domain 1 of 1, from 556 to 624: score 95.8, E = 4e-27
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ksef+ n+sHELRTPL++++g++++Ll+ + +el++ q
CP001994_0 556 MKSEFITNMSHELRTPLNSVIGFSDVLLK------EIKGELNDSQ-- 594

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++y++ i +++++ll+Lind+Ldls+ie+g
CP001994_0 595 ----------KKYISNISKSGRHLLELINDILDLSKIEEG 624

CP001994_0895: domain 1 of 1, from 511 to 579: score 94.4, E = 9.8e-27
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
kseflan+sHELRTPL++++g++++L++++ + +l++++
CP001994_0 511 TKSEFLANMSHELRTPLNSVIGFSQVLETNS------SNHLDDKE-- 549

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++y++ i++++ +ll+Lin++Ld+s+ e+g
CP001994_0 550 ----------QKYVKNIYESGSHLLELINNILDISKVESG 579

CP001994_1516: domain 1 of 1, from 863 to 931: score 92.4, E = 3.8e-26
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+kseflan+sHELRTPL++I+g++++L e + ++l+ +q
CP001994_1 863 SKSEFLANMSHELRTPLNSIIGFSDILNGETF------GKLTQKQ-- 901

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++y+ i +++++ll Lin++Ldls+ieag
CP001994_1 902 ----------EKYTANINKSGKHLLYLINEILDLSKIEAG 931

CP001994_1953: domain 1 of 1, from 404 to 472: score 92.3, E = 4e-26
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
ak+eflan+sHELRTPL+aI+g++++L + ++++l++++
CP001994_1 404 AKTEFLANVSHELRTPLNAIIGFSQILST------NKSGNLNDKE-- 442

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+y++ il+++++ll+Lin +Ld+s+++ag
CP001994_1 443 ----------LKYVSNILKSGNHLLELINKILDISKLQAG 472

CP001994_1355: domain 1 of 1, from 501 to 569: score 90.9, E = 9.8e-26
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+k+efl+n+sHEL+TPLt+I+gy+elL + ++ +el+eeq
CP001994_1 501 MKDEFLSNVSHELKTPLTSIIGYTELLND------GSLGELGEEQ-- 539

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + et+ r ++rl+rL++ lL lsr +ag
CP001994_1 540 ----------KHAEETVMRNTKRLQRLVDSLLYLSRTQAG 569

CP001994_0806: domain 1 of 1, from 350 to 416: score 88.0, E = 6.5e-25
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k+efl+++sHEL+TPLtaIr+ +e L+e ++ + e++
CP001994_0 350 VKNEFLSMVSHELKTPLTAIRTSSEFLRE---------EDYDRETQ- 386

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e+l+ i+r ++r +r+++dlLd+srie+g
CP001994_0 387 ----------EEMLDLIIRNIDRQSRMVDDLLDISRIESG 416

CP001994_0108: domain 1 of 1, from 370 to 438: score 87.8, E = 7.6e-25
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
kseflan+sHELRTPL++I+gy+++L +++l+e++
CP001994_0 370 TKSEFLANMSHELRTPLNSIIGYSQILNQ------NPSGNLDEKE-- 408

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+y + il+++e+ll+Lin +Ld+s+ eag
CP001994_0 409 ----------LKYSHNILNSGEHLLELINSILDISKVEAG 438

CP001994_0581: domain 1 of 1, from 483 to 551: score 84.0, E = 9e-24
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
ksef+ ++sHELRTPL++I+g++++Lle + se +++
CP001994_0 483 TKSEFMTTMSHELRTPLNSIIGFSQMLLE---------VPGSELTNA 520

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++y++ il+++++ll+Lind+Ld+s+ eag
CP001994_0 521 H---------HKYVSNILKSGKSLLHLINDILDISKVEAG 551

CP001994_0191: domain 1 of 1, from 390 to 458: score 80.9, E = 7e-23
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k+ef+a++sHELRTPL+aI+g+++lL + + ++++e++
CP001994_0 390 TKTEFIATMSHELRTPLNAIIGFSQLLSSNRY------GNMNEKE-- 428

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+y +il+ +++ll+Lind+Ld+s+i ++
CP001994_0 429 ----------LKYSFSILKGGKHLLNLINDILDFSKIHSN 458

CP001994_1036: domain 1 of 1, from 405 to 473: score 69.5, E = 1.1e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+k+efl+n+sHEL+TPLt I+gy+elL e ++ + l+ eq+
CP001994_1 405 MKDEFLSNVSHELKTPLTLIKGYTELLCE------GKMGQLNKEQI- 444

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e +++ r aerl rL++ lL ls+i+a
CP001994_1 445 -----------EVQNKVVRNAERLKRLVDSLLYLSKIQAS 473

CP001994_1215: domain 1 of 1, from 329 to 397: score 64.3, E = 3.5e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
kseflanl HEL+TPL +I+g+++lL + ++ +el+e+q
CP001994_1 329 LKSEFLANLTHELKTPLISIKGFSDLLDK------GRLGELNEDQ-- 367

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ + r a+rl rLi+ lL +s +g
CP001994_1 368 ----------KKANLAVVRNADRLKRLIDSLLYMSMEKEG 397

CP001994_0816: domain 1 of 1, from 735 to 803: score 60.9, E = 3.2e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
se+ anl HELRT L I+g++++L ++ + + l+++q
CP001994_0 735 TNSELKANLGHELRTSLGNIIGFTQMLHNNIY------GRLNPKQ-- 773

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ ++ i+++ae+l +Li+d+L++s eag
CP001994_0 774 ----------QKHIQGIQKSAEHLMNLIDDILEISDVEAG 803

CP001994_1905: domain 1 of 1, from 274 to 341: score 43.8, E = 2.3e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k ef+an sHELRTP+ +++g+++lL + + +el++eq
CP001994_1 274 VKKEFIANTSHELRTPMISLKGFSDLLNK------ERLGELGPEQ-- 312

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ e+i r + l rLi+ L ++ +
CP001994_1 313 ----------KKAMESISRNSIFLHRLIES-LFYANDTTR 341

CP001994_0596: domain 1 of 1, from 270 to 327: score 38.9, E = 5.4e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++eflan+s EL PL++I+g++ lL + ++++e +++q
CP001994_0 270 MRNEFLANISKELQMPLASIKGFSNLLAR------GEYGEINSKQ-- 308

peLRledpeyreyletilreaerllrLin<-*
r++l ti r +rl++ +n
CP001994_0 309 ----------RDALLTITRNCDRLQKHVN 327

CP001994_0337: domain 1 of 1, from 152 to 217: score 38.4, E = 7.4e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k+ f +sH+L++P I+gy++lL + e ++e+
CP001994_0 152 IKELFGDIVSHDLKNPAGIIKGYSQLLAD---------REEGAEK-- 187

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ ti r ++r+l+Li++ + ++++
CP001994_0 188 ----------KKIALTINRNINRILELIENASVFVKLDTL 217

CP001994_1216: domain 1 of 1, from 714 to 779: score 35.7, E = 4.2e-10
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+k+ f+ ++H+L +P + ++g++++L + e+ e+++
CP001994_1 714 MKDLFTDIMRHDLLNPANIVKGFTDILIK---------NEKEEKKI- 750

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+l++i++ +erl ++i++ ls++e+
CP001994_1 751 -----------HFLSRIRDNTERLIDMIENTAYLSKLEST 779


Histogram of all scores:
score obs exp (one = represents 7 sequences)
----- --- ---
-15 1 0|=
-14 17 0|===
-13 46 1|*======
-12 117 45|======*==========
-11 263 235|=================================*====
-10 376 436|====================================================== *
-9 347 451|================================================== *
-8 291 337|========================================== *
-7 200 212|============================= *
-6 138 122|=================*==
-5 81 67|=========*==
-4 43 35|====*==
-3 21 19|==*
-2 10 9|=*
-1 10 5|*=
0 2 2|*
1 2 1|*
2 1 0|=
3 1 0|=
> 4 20 -|===


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 166.6601
P(chi-square) = 5.738e-30

Total sequences searched: 1987

Whole sequence top hits:
tophits_s report:
Total hits: 19
Satisfying E cutoff: 19
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 19
Satisfying E cutoff: 19
Total memory: 28K


Acknowledgements:

This research is funded by:

Developed by: