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Aquificae Bacteroidetes/Chlorobi Betaproteobacteria
Chlamydiae/Verrucomicrobia Chloroflexi Cyanobacteria
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Firmicutes Fusobacteria Gammaproteobacteria
Other Bacteria Planctomycetes Spirochaetes
Thermotogae
Classification of phyla is from NCBI page
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76 projects found  

4 accessions found for Burkholderia sp. CCGE1002  

Data for CP002014  

Available Atlases
Other Plots
hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: CP002014.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
CP002014_0391 CDS_431213-434152 84.8 5.9e-24 1
CP002014_0752 CDS_854539-850958 80.8 8e-23 1
CP002014_0167 CDS_182004-183935 73.9 7.4e-21 1
CP002014_0344 CDS_376911-378413 71.6 3.2e-20 1
CP002014_0749 CDS_849413-848286 63.8 5.3e-18 1
CP002014_0470 CDS_529143-531038 63.5 6.7e-18 1
CP002014_0530 CDS_595477-596877 61.2 2.9e-17 1
CP002014_2111 CDS_2416448-2417863 60.3 5.5e-17 1
CP002014_0513 CDS_577064-578911 53.9 3.4e-15 1
CP002014_1463 CDS_1660445-1659060 51.2 2e-14 1
CP002014_2087 CDS_2392109-2386536 44.6 1.5e-12 2
CP002014_2226 CDS_2557825-2559276 43.8 2.6e-12 1
CP002014_2019 CDS_2285858-2284200 42.7 5.3e-12 1
CP002014_1594 CDS_1800445-1799090 36.1 3.7e-10 1
CP002014_1686 CDS_1911974-1910424 35.3 6.4e-10 1
CP002014_1671 CDS_1897862-1892331 35.1 7.3e-10 2
CP002014_2106 CDS_2410718-2412994 33.8 1.7e-09 1
CP002014_1593 CDS_1799081-1797957 33.2 2.6e-09 1
CP002014_1931 CDS_2177398-2178219 30.9 1.1e-08 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CP002014_0391 1/1 493 558 .. 1 87 [] 84.8 5.9e-24
CP002014_0752 1/1 494 562 .. 1 87 [] 80.8 8e-23
CP002014_0167 1/1 268 335 .. 1 87 [] 73.9 7.4e-21
CP002014_0344 1/1 234 300 .. 1 87 [] 71.6 3.2e-20
CP002014_0749 1/1 146 211 .. 1 87 [] 63.8 5.3e-18
CP002014_0470 1/1 217 283 .. 1 87 [] 63.5 6.7e-18
CP002014_0530 1/1 246 312 .. 1 87 [] 61.2 2.9e-17
CP002014_2111 1/1 249 315 .. 1 87 [] 60.3 5.5e-17
CP002014_0513 1/1 245 310 .. 1 87 [] 53.9 3.4e-15
CP002014_1463 1/1 236 302 .. 1 87 [] 51.2 2e-14
CP002014_2226 1/1 252 322 .. 1 87 [] 43.8 2.6e-12
CP002014_2087 1/2 1633 1703 .. 1 87 [] 43.7 2.6e-12
CP002014_2019 1/1 194 259 .. 1 87 [] 42.7 5.3e-12
CP002014_1594 1/1 228 296 .. 1 87 [] 36.1 3.7e-10
CP002014_1686 1/1 278 348 .. 1 87 [] 35.3 6.4e-10
CP002014_2106 1/1 508 578 .. 1 87 [] 33.8 1.7e-09
CP002014_1671 2/2 1612 1682 .. 1 87 [] 33.4 2.2e-09
CP002014_1593 1/1 141 202 .. 1 78 [. 33.2 2.6e-09
CP002014_1931 1/1 35 102 .. 1 87 [] 30.9 1.1e-08

Alignments of top-scoring domains:
CP002014_0391: domain 1 of 1, from 493 to 558: score 84.8, E = 5.9e-24
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks fla++sHE+RTPL+aI+g++elL + ++ls+ q
CP002014_0 493 AKSAFLAMMSHEIRTPLNAILGNLELLGR---------SPLSPLQ-- 528

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e + ++ +++ ll +ind+Ld+s+ e+g
CP002014_0 529 ----------EERVGVVTSSSTALLGIINDILDFSKVESG 558

CP002014_0752: domain 1 of 1, from 494 to 562: score 80.8, E = 8e-23
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
kseflan+sHELRTPL++ + +a+lL+ ++++l++eq
CP002014_0 494 YKSEFLANMSHELRTPLNSSLILAKLLQQ------NRSGNLTDEQ-- 532

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+y eti+ + ll Lind+Ldls+ eag
CP002014_0 533 ----------VRYAETIHASNSDLLVLINDILDLSKVEAG 562

CP002014_0167: domain 1 of 1, from 268 to 335: score 73.9, E = 7.4e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+k+efla+l+HELR+PL+ Ir ++elL + ++++q
CP002014_0 268 RKDEFLAMLAHELRNPLAPIRNAIELLDP---------SRAPSQQS- 304

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ + +i r++++l+rL++dlLd +ri +g
CP002014_0 305 ---------FEAMRAVIGRQVKHLSRLVDDLLDVARITQG 335

CP002014_0344: domain 1 of 1, from 234 to 300: score 71.6, E = 3.2e-20
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++ f a+++HELRTP+t ++g +e++l+ ++s +++
CP002014_0 234 RLESFNADVAHELRTPVTILIGQTEVALT---------RNRSVDDL- 270

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r l++ l+e er++++ind+L l+r+++g
CP002014_0 271 ----------RHTLQSNLEEFERMRAIINDMLFLARADQG 300

CP002014_0749: domain 1 of 1, from 146 to 211: score 63.8, E = 5.3e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a + ++a lsH+LRTPL a+++ ae L + t+++e+
CP002014_0 146 ANEMLMAVLSHDLRTPLGAVLASAEYLMR---------TAADEQA-- 181

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ ++++++ r+ r++++lL l+r++ g
CP002014_0 182 ----------ATVAARVKNSSLRMARMVDQLLNLARLQGG 211

CP002014_0470: domain 1 of 1, from 217 to 283: score 63.5, E = 6.7e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
ak++f+a++sH+LR+PL+aI ++a L + +++++ q+
CP002014_0 217 AKTRFFAAASHDLRQPLHAIGLLAASLND---------PAATPAQH- 253

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ i +e l++L n++Ldl+r+e+g
CP002014_0 254 ----------AKTAGHIVYNVEALNQLFNQVLDLARLESG 283

CP002014_0530: domain 1 of 1, from 246 to 312: score 61.2, E = 2.9e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f a+l+HE+RTP+ a+ g ++++l+ +++ +++
CP002014_0 246 RLQQFSADLAHEIRTPVGALVGQTQVALA---------QPREPDE-- 281

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
y+++le+ l+e++rl+++ +++L l+ +++
CP002014_0 282 ---------YQQLLESNLEELNRLSHIAENILFLAHADHA 312

CP002014_2111: domain 1 of 1, from 249 to 315: score 60.3, E = 5.5e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++s+ +a+l+H++RTPL +rg++e++l+ ++s +
CP002014_2 249 RMSQYTADLAHDMRTPLGNLRGATEVALT---------RPRSTAE-- 284

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
y+ +le+ l+e +rl+r+i+ + l+r+e++
CP002014_2 285 ---------YEALLESNLEECDRLSRMIESVIFLARAEHP 315

CP002014_0513: domain 1 of 1, from 245 to 310: score 53.9, E = 3.4e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
ak+ fl ++sHELRTPL+aI +elL + se +
CP002014_0 245 AKDAFLGMISHELRTPLHAIVSSVELLGF---------HYHSEAD-- 280

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+ +++++ +a++l+++ dl d++r++ag
CP002014_0 281 ----------RKVIQRLETAARHLEAQMKDLTDYARLGAG 310

CP002014_1463: domain 1 of 1, from 236 to 302: score 51.2, E = 2e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+++f+a+++H+LRTPLt + + ++ ++ +e + +
CP002014_1 236 AQRRFIADAAHQLRTPLTLLGTQLQFARQ---------QEGLNPAL- 272

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e+l ++r+ +++ L n lL l+++ea
CP002014_1 273 ----------DEALAAMHRSNRSMVGLTNKLLLLAQAEAA 302

CP002014_2226: domain 1 of 1, from 252 to 322: score 43.8, E = 2.6e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++e++ +l+HEL++PLtaI+++a++++++ld +++ + ++
CP002014_2 252 SLGELAGSLAHELKQPLTAILFNAQAARKFLD-----SETTNVVEL- 292

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
re+le i + r ++ ++ ++ l r +
CP002014_2 293 ----------REALEDIVADNCRANDVLQKIRALVRKGDV 322

CP002014_2087: domain 1 of 2, from 1633 to 1703: score 43.7, E = 2.6e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++a++sHE ++P++a+ ++ +++l++l + ++++ + +
CP002014_2 1633 TIGQLTATISHEVKQPIAAMAANGDAALRWL-----SAAPANVDRA- 1673

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r++l+ i r+a r ++i++++ l r
CP002014_2 1674 ----------RDALNLIVRDAMRAGDIIDRIRNLVRKTPA 1703

CP002014_2019: domain 1 of 1, from 194 to 259: score 42.7, E = 5.3e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+++++ +++H++++ L++I+ +ael+ + ++
CP002014_2 194 ALGQLTGGIAHDFNNLLNVIMVNAELIAR---------VSGDDRL-- 229

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r + t++r++er +L +lL++sr ++
CP002014_2 230 ----------RGMAATVKRATERGAKLTGQLLTFSRNSNP 259

CP002014_1594: domain 1 of 1, from 228 to 296: score 36.1, E = 3.7e-10
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a + ++a+l HE ++P++ ++++e++le ++ s ++
CP002014_1 228 AIGTLAAGLLHEVNNPVNFCLMAIEVALE---------EPISKKE-- 263

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
p L +e l +++ +r++++++dl +++ g
CP002014_1 264 PTL-------QECLVDARQGMQRIQHIVSDLKTFAYRKPG 296

CP002014_1686: domain 1 of 1, from 278 to 348: score 35.3, E = 6.4e-10
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++++a+++HEL +P+++ ae++l++ld +++++ +++
CP002014_1 278 TMGQLAASIAHELSQPIASTVISAEAALRWLD-----REPADIDEA- 318

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++l++i a+r + + ++++l r
CP002014_1 319 ----------SRALDSIVGGANRAADVLGRIRQLVRKAPR 348

CP002014_2106: domain 1 of 1, from 508 to 578: score 33.8, E = 1.7e-09
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++e++a+++HE +P++a+ + +++l++l +d+++ +e
CP002014_2 508 TLGELAASIAHEVTQPIAAVVTSGDAALRWL----RRDPPKLDEV-- 548

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ + ++++++r ++++++++ +++ +
CP002014_2 549 ----------ERSVGQMIKSVKRANEIVRQIRAMAQKRPA 578

CP002014_1671: domain 2 of 2, from 1612 to 1682: score 33.4, E = 2.2e-09
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ ++a+++H+ ++PL++I++ a+++l++l +t+ + ++
CP002014_1 1612 TLNALTASIAHDVNQPLASIITDAKAALRWLA-----RTPPDLGEL- 1652

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e +e+i + ++r ++ i ++ l + ++
CP002014_1 1653 ----------KETVERIVEGGHRASAVIAGVRALLKKSSP 1682

CP002014_1593: domain 1 of 1, from 141 to 202: score 33.2, E = 2.6e-09
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a +e la ++HEL+TPL+aI ++a+ ++++ d +e+++e
CP002014_1 141 AIDETLAFIAHELNTPLAAIALNAHSIEDRTD------AERDAEG-- 179

peLRledpeyreyletilreaerllrLindl<-*
e+ + ++++++a+++ + ++ +
CP002014_1 180 --------EILGAAKSMRESAQYCMAVVSSF 202

CP002014_1931: domain 1 of 1, from 35 to 102: score 30.9, E = 1.1e-08
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++ l+ +sH+LR PL+aI a +L+++l ++ ++
CP002014_1 35 MRDHVLSLVSHDLRGPLNAIHSWAYVLERKL-------DANDPNS-- 72

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++++ i++ +++ +L++ + d +r+e+
CP002014_1 73 ----------QRAITGIRSGVDQQVKLLETIVDTTRAETK 102


Histogram of all scores:
score obs exp (one = represents 8 sequences)
----- --- ---
-15 1 0|=
-14 6 0|=
-13 28 1|*===
-12 93 51|======*=====
-11 200 267|========================= *
-10 374 496|=============================================== *
-9 437 512|======================================================= *
-8 404 383|===============================================*===
-7 284 241|==============================*=====
-6 175 139|=================*====
-5 102 76|=========*===
-4 58 40|====*===
-3 31 21|==*=
-2 15 11|=*
-1 10 5|*=
0 4 3|*
1 6 1|*
> 2 30 -|====


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 133.1397
P(chi-square) = 4.026e-23

Total sequences searched: 2258

Whole sequence top hits:
tophits_s report:
Total hits: 19
Satisfying E cutoff: 19
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 19
Satisfying E cutoff: 19
Total memory: 28K


Acknowledgements:

This research is funded by:

Developed by: