Acidobacteria Actinobacteria Alphaproteobacteria
Aquificae Bacteroidetes/Chlorobi Betaproteobacteria
Chlamydiae/Verrucomicrobia Chloroflexi Cyanobacteria
Deinococcus-Thermus Deltaproteobacteria Epsilonproteobacteria
Firmicutes Fusobacteria Gammaproteobacteria
Other Bacteria Planctomycetes Spirochaetes
Thermotogae
Classification of phyla is from NCBI page
Search:
7 projects found  

3 accessions found for Meiothermus silvanus DSM 9946  

Data for CP002042  

Available Atlases
Other Plots
hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: CP002042.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
CP002042_0895 CDS_922470-919987 93.8 2.3e-26 1
CP002042_2539 CDS_2680950-2682377 87.7 1.3e-24 1
CP002042_2871 CDS_3027953-3029107 76.2 2.3e-21 1
CP002042_0138 CDS_148169-147072 75.5 3.6e-21 1
CP002042_3024 CDS_3196923-3195604 70.2 1.1e-19 1
CP002042_1055 CDS_1089426-1088098 65.3 2.7e-18 1
CP002042_1343 CDS_1384097-1385470 64.3 5.2e-18 1
CP002042_1024 CDS_1059566-1060843 59.5 1.2e-16 1
CP002042_0783 CDS_808700-807459 55.3 1.9e-15 1
CP002042_0703 CDS_728082-726856 54.9 2.4e-15 1
CP002042_0805 CDS_834658-833621 49.8 6.9e-14 1
CP002042_2877 CDS_3034520-3035752 49.5 8.4e-14 1
CP002042_3022 CDS_3194862-3193552 47.9 2.4e-13 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CP002042_0895 1/1 598 664 .. 1 87 [] 93.8 2.3e-26
CP002042_2539 1/1 249 315 .. 1 87 [] 87.7 1.3e-24
CP002042_2871 1/1 158 225 .. 1 87 [] 76.2 2.3e-21
CP002042_0138 1/1 139 202 .. 1 87 [] 75.5 3.6e-21
CP002042_3024 1/1 217 282 .. 1 87 [] 70.2 1.1e-19
CP002042_1055 1/1 217 279 .. 1 87 [] 65.3 2.7e-18
CP002042_1343 1/1 244 306 .. 1 87 [] 64.3 5.2e-18
CP002042_1024 1/1 200 264 .. 1 87 [] 59.5 1.2e-16
CP002042_0783 1/1 218 281 .. 1 87 [] 55.3 1.9e-15
CP002042_0703 1/1 189 253 .. 1 87 [] 54.9 2.4e-15
CP002042_0805 1/1 106 170 .. 1 87 [] 49.8 6.9e-14
CP002042_2877 1/1 163 229 .. 1 87 [] 49.5 8.4e-14
CP002042_3022 1/1 217 283 .. 1 87 [] 47.9 2.4e-13

Alignments of top-scoring domains:
CP002042_0895: domain 1 of 1, from 598 to 664: score 93.8, E = 2.3e-26
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
ksef+a++sHELRTPL+aI+g+aelL +e + e+
CP002042_0 598 IKSEFIAAVSHELRTPLAAIMGFAELLTS---------GEIPLEEG- 634

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e+l++i++ ++rl +++++lLd sr+eag
CP002042_0 635 ----------QEFLRIIYDNGRRLKNMVDNLLDSSRLEAG 664

CP002042_2539: domain 1 of 1, from 249 to 315: score 87.7, E = 1.3e-24
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++fla++sHELRTP+taI+g+++ Ll+ +t+l+e+q
CP002042_2 249 TQTRFLADASHELRTPVTAILGHVSYLLR--------RTPLTEQQ-- 285

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
re le+++re+er+ +L+ dlL+ls+ +
CP002042_2 286 ----------RESLEIVRREGERMKKLVGDLLELSKTGGT 315

CP002042_2871: domain 1 of 1, from 158 to 225: score 76.2, E = 2.3e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+++f+a+++HELR PLtaI+g++elL + ++e+++++r
CP002042_2 158 AQQRFVADAAHELRAPLTAIQGNLELLYR--------YPEMPPQDR- 195

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e + +l+ea+rl rL+ d+L l+r +ag
CP002042_2 196 ----------MESVIQALQEARRLGRLVADMLALARGDAG 225

CP002042_0138: domain 1 of 1, from 139 to 202: score 75.5, E = 3.6e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ e++ +++HELRTPL++++gyae+L + + l++eq+
CP002042_0 139 SRVELIGSVAHELRTPLAGLQGYAEALAD---------GVLPPEQA- 175

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++i +e++ ++rL++dl sr eag
CP002042_0 176 -------------AHRIAHEVRAMRRLVEDLSLVSRVEAG 202

CP002042_3024: domain 1 of 1, from 217 to 282: score 70.2, E = 1.1e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++f+ +++HELRTPLt+++g +e ++e ++++++
CP002042_3 217 SERRFTQDAAHELRTPLTVLLGRLEQAQE---------ENRDPQV-- 252

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++le ++r+a r+l+L++ lL l+r+eag
CP002042_3 253 ----------ARALEHAHRSAGRMLALVEKLLHLARAEAG 282

CP002042_1055: domain 1 of 1, from 217 to 279: score 65.3, E = 2.7e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ + fla +sHELRTPLt++ gy+e L + ++ +
CP002042_1 217 RERAFLAEVSHELRTPLTSLTGYLERLSR------------NPAE-- 249

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +le ++r +e+l r++ dlL l+r ea+
CP002042_1 250 ----------QSALEGAKRTTEHLTRMVGDLLALARGEAE 279

CP002042_1343: domain 1 of 1, from 244 to 306: score 64.3, E = 5.2e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ +f+ ++sHELR+PL+a++gy+e+L ++ + +
CP002042_1 244 SAKRFAYGASHELRNPLAALKGYLEVLARR------------PGE-- 276

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++e +lrea+r+++L++ lL+l+r+e
CP002042_1 277 ----------LRAIEGALREARRMESLLEGLLTLARLEGR 306

CP002042_1024: domain 1 of 1, from 200 to 264: score 59.5, E = 1.2e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ ++a+++HELRTPLt ++g +e++++++ + l +
CP002042_1 200 ERKAMIADIAHELRTPLTIMQGRLEAIQDGV-------ASLEMRE-- 237

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++++++++ l+rL++dl++ls ++ag
CP002042_1 238 -------------IDRLHHQTRLLSRLVEDLRTLSLADAG 264

CP002042_0783: domain 1 of 1, from 218 to 281: score 55.3, E = 1.9e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++fla+++HELRTPL+a r+ +e+++ + l +eq
CP002042_0 218 REQRFLAYAAHELRTPLSAFRASLEAARI--------KGQLEAEQ-- 254

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
l++++rea rl+ L ++lL lsr+eag
CP002042_0 255 -------------LSRLHREALRLETLAQNLLALSRAEAG 281

CP002042_0703: domain 1 of 1, from 189 to 253: score 54.9, E = 2.4e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ ++a+++H+LRTPL+++r +e++++++ + ++
CP002042_0 189 WRRGLVADIAHDLRTPLAVLRSEIEAMQDGV-------AQPNAAG-- 226

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
le+++ ++ +l++L++dl++ls +e+g
CP002042_0 227 -------------LERLHGQVMHLSKLVDDLRTLSLAESG 253

CP002042_0805: domain 1 of 1, from 106 to 170: score 49.8, E = 6.9e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++e ++l+HE+RTP+++++ ++++Lle l+ +++
CP002042_0 106 ALEEASRTLAHEFRTPVAGMLSLLDALLE----------GLPQPEA- 141

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e+le i++ea rl+rL++d L l r+ ++
CP002042_0 142 ----------KEALEMIRHEALRLSRLVED-LPLNRLPSQ 170

CP002042_2877: domain 1 of 1, from 163 to 229: score 49.5, E = 8.4e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++ fl ++ HE+RTP++++r++ae+L++ el+ e++
CP002042_2 163 RQQNFLMAVTHEFRTPISTVRLLAETLER---------RELPREKQ- 199

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
yl +++e+ rl++L ++lL +r+e+
CP002042_2 200 ----------LGYLAHMEQELSRLEALSERLLATARLEQS 229

CP002042_3022: domain 1 of 1, from 217 to 283: score 47.9, E = 2.4e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ f+ +++HELRTPL+ ++g a+l le ++++eq
CP002042_3 217 REKAFALAAAHELRTPLSLLQGRASLSLE---------RPRTPEQ-- 252

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
yre+l i r ae l + i+ lL l+ + +
CP002042_3 253 ---------YREALVEIARTAEDLAQVIEALLLLAHTQVP 283


Histogram of all scores:
score obs exp (one = represents 10 sequences)
----- --- ---
-15 2 0|=
-14 8 0|=
-13 42 2|*====
-12 109 70|======*====
-11 297 364|============================== *
-10 497 675|================================================== *
-9 589 697|==========================================================*
-8 528 522|====================================================*
-7 354 329|================================*===
-6 283 189|==================*==========
-5 154 103|==========*=====
-4 98 55|=====*====
-3 46 29|==*==
-2 25 15|=*=
-1 12 8|*=
0 10 4|*
1 2 2|*
> 2 16 -|==


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 219.7924
P(chi-square) = 1.08e-310

Total sequences searched: 3072

Whole sequence top hits:
tophits_s report:
Total hits: 13
Satisfying E cutoff: 13
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 13
Satisfying E cutoff: 13
Total memory: 26K


Acknowledgements:

This research is funded by:

Developed by: