Acidobacteria Actinobacteria Alphaproteobacteria
Aquificae Bacteroidetes/Chlorobi Betaproteobacteria
Chlamydiae/Verrucomicrobia Chloroflexi Cyanobacteria
Deinococcus-Thermus Deltaproteobacteria Epsilonproteobacteria
Firmicutes Fusobacteria Gammaproteobacteria
Other Bacteria Planctomycetes Spirochaetes
Thermotogae
Classification of phyla is from NCBI page
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76 projects found  

1 accessions found for Methylotenera sp. 301  

Data for CP002056  

Available Atlases
Other Plots
hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: CP002056.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
CP002056_0680 CDS_766484-762765 93.1 3.3e-26 1
CP002056_2442 CDS_2716826-2719045 86.9 1.9e-24 1
CP002056_2309 CDS_2569960-2572005 85.5 4.6e-24 1
CP002056_0539 CDS_600408-597481 81.7 5.7e-23 1
CP002056_0499 CDS_557936-556602 80.5 1.2e-22 1
CP002056_0960 CDS_1091538-1094159 79.6 2.2e-22 1
CP002056_1365 CDS_1518812-1522258 79.1 3e-22 1
CP002056_1102 CDS_1238031-1236598 68.5 3.1e-19 1
CP002056_0266 CDS_310882-309176 65.9 1.7e-18 1
CP002056_1015 CDS_1142809-1141556 63.1 1e-17 1
CP002056_0067 CDS_89729-91090 60.5 5.6e-17 1
CP002056_0877 CDS_1005626-1004121 60.2 7e-17 1
CP002056_2523 CDS_2795280-2796374 59.3 1.2e-16 1
CP002056_0447 CDS_496867-495494 53.8 4.4e-15 1
CP002056_1657 CDS_1869919-1868816 51.8 1.7e-14 1
CP002056_1894 CDS_2133843-2135531 50.5 3.9e-14 1
CP002056_0609 CDS_672833-674236 50.3 4.3e-14 1
CP002056_2016 CDS_2266733-2268190 48.3 1.6e-13 1
CP002056_0214 CDS_250627-252783 47.4 3e-13 1
CP002056_1810 CDS_2054698-2053403 45.2 1.3e-12 1
CP002056_2111 CDS_2366317-2367630 44.9 1.5e-12 1
CP002056_2427 CDS_2699135-2700598 36.3 4.2e-10 1
CP002056_1653 CDS_1864350-1865864 34.7 1.2e-09 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CP002056_0680 1/1 658 723 .. 1 87 [] 93.1 3.3e-26
CP002056_2442 1/1 197 262 .. 1 87 [] 86.9 1.9e-24
CP002056_2309 1/1 303 370 .. 1 87 [] 85.5 4.6e-24
CP002056_0539 1/1 733 801 .. 1 87 [] 81.7 5.7e-23
CP002056_0499 1/1 205 272 .. 1 87 [] 80.5 1.2e-22
CP002056_0960 1/1 496 563 .. 1 87 [] 79.6 2.2e-22
CP002056_1365 1/1 694 760 .. 1 87 [] 79.1 3e-22
CP002056_1102 1/1 252 320 .. 1 87 [] 68.5 3.1e-19
CP002056_0266 1/1 355 421 .. 1 87 [] 65.9 1.7e-18
CP002056_1015 1/1 201 262 .. 1 87 [] 63.1 1e-17
CP002056_0067 1/1 226 291 .. 1 87 [] 60.5 5.6e-17
CP002056_0877 1/1 277 343 .. 1 87 [] 60.2 7e-17
CP002056_2523 1/1 131 188 .. 1 79 [. 59.3 1.2e-16
CP002056_0447 1/1 233 298 .. 1 87 [] 53.8 4.4e-15
CP002056_1657 1/1 145 208 .. 1 87 [] 51.8 1.7e-14
CP002056_1894 1/1 347 413 .. 1 87 [] 50.5 3.9e-14
CP002056_0609 1/1 242 307 .. 1 87 [] 50.3 4.3e-14
CP002056_2016 1/1 256 321 .. 1 87 [] 48.3 1.6e-13
CP002056_0214 1/1 488 560 .. 1 87 [] 47.4 3e-13
CP002056_1810 1/1 213 278 .. 1 87 [] 45.2 1.3e-12
CP002056_2111 1/1 229 290 .. 1 87 [] 44.9 1.5e-12
CP002056_2427 1/1 270 321 .. 1 73 [. 36.3 4.2e-10
CP002056_1653 1/1 276 346 .. 1 87 [] 34.7 1.2e-09

Alignments of top-scoring domains:
CP002056_0680: domain 1 of 1, from 658 to 723: score 93.1, E = 3.3e-26
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
ak flan+sHE+RTP++aI+g++e++ + te+ +eq
CP002056_0 658 AKATFLANMSHEIRTPMNAIIGFSEIMMD---------TEMQDEQ-- 693

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+y +ti ++a++ll+L+nd+Ld +++e g
CP002056_0 694 ----------RRYMNTINNSAKSLLHLLNDILDSAKLEKG 723

CP002056_2442: domain 1 of 1, from 197 to 262: score 86.9, E = 1.9e-24
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
ak++f+an+sHE+RTPL++I+g + lL++ t+l+ +q
CP002056_2 197 AKTQFVANMSHEIRTPLNGIIGISTLLKT---------TPLNTDQ-- 232

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l+t++ +++ ll+L+n++Ld+++ie+
CP002056_2 233 ----------QDLLKTLEGSSKLLLSLLNNVLDFTKIEER 262

CP002056_2309: domain 1 of 1, from 303 to 370: score 85.5, E = 4.6e-24
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks+fl+n+sHELRTPL+aI+g+a+lL+ + t+++ e++
CP002056_2 303 AKSDFLSNMSHELRTPLNAILGFAQLLEGG--------TPAPTETQ- 340

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ l+ il+++ +l ++in++Ldl++ie+g
CP002056_2 341 ----------TKRLKEILKAGWYLTDMINEILDLAKIESG 370

CP002056_0539: domain 1 of 1, from 733 to 801: score 81.7, E = 5.7e-23
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
ks f+a++sHELRTPL++I+g++ + l ++ +++l+ +q
CP002056_0 733 IKSMFVASMSHELRTPLNSIIGFLGVVLQGM------SGDLNTKQ-- 771

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ l +++++a++ll+Li+d+ d+s+ieag
CP002056_0 772 ----------KDQLGRAYHSAKHLLSLISDVIDISKIEAG 801

CP002056_0499: domain 1 of 1, from 205 to 272: score 80.5, E = 1.2e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+an+sHELRTPLt++ g++e+L + e +++l
CP002056_0 205 MRRDFIANVSHELRTPLTVVGGFLETLTD---------MEGAVPDNL 242

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ y+ +++++ r++r+i+dlL+ls ie++
CP002056_0 243 ----------KNYFAMMEEQTIRMRRIIEDLLTLSSIESN 272

CP002056_0960: domain 1 of 1, from 496 to 563: score 79.6, E = 2.2e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks+fl+++sHELRTPL aI+g+a+l++ g ++ ++ q
CP002056_0 496 AKSDFLSSMSHELRTPLGAILGFAQLIES-------GTPAPTASQ-- 533

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ ++ il+++ +ll+Lin++Ldl+ ie+g
CP002056_0 534 ----------KKSIDQILKAGWYLLELINEVLDLALIESG 563

CP002056_1365: domain 1 of 1, from 694 to 760: score 79.1, E = 3e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks+ + ++sHELRTPL++I+gya+lL + dt ++
CP002056_1 694 AKSRYITGISHELRTPLNSILGYAQLLDN--------DTSIPDSR-- 730

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++++i+r++e+ll+Li+ Ld++rie g
CP002056_1 731 ----------LQAIRVIRRSGEHLLSLIEGTLDIARIEGG 760

CP002056_1102: domain 1 of 1, from 252 to 320: score 68.5, E = 3.1e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+k++fl+++sHEL+TPLtaIr ++elL + ++ ++l+++q
CP002056_1 252 QKQQFLRHVSHELKTPLTAIREATELLYD------GIGGALTAQQ-- 290

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e++ ++++ + rl+r+i++lL ++r+e+
CP002056_1 291 ----------SEITLILRENSIRLQRMIENLLNYTRMESI 320

CP002056_0266: domain 1 of 1, from 355 to 421: score 65.9, E = 1.7e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+++++an++HE+R+PL+aI+ + +lL+e +e +++ +
CP002056_0 355 ALGRLTANIAHEIRNPLSAISHANQLLQE---------DENNSKST- 391

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++le++ + + r++++i d+L+l r +
CP002056_0 392 ----------ERLLEIVADNIGRIDQIIKDVLELNRRDRT 421

CP002056_1015: domain 1 of 1, from 201 to 262: score 63.1, E = 1e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++++l ++sHE+R PL+ +++++ l++ +++
CP002056_1 201 AQTRLLHHVSHEMRSPLARMQMALGLMKQ-------------DPT-- 232

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++l++i+ ea+r++ L+ +lL+ls++e+g
CP002056_1 233 ----------SDFLDRIELEANRIDGLVGELLELSKLESG 262

CP002056_0067: domain 1 of 1, from 226 to 291: score 60.5, E = 5.6e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++f+a+++HELRTPL+a++ a+++l+ ++ +e
CP002056_0 226 GERRFTADAAHELRTPLAALKIQAQVALR---------STNKAER-- 261

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+le +l+ ++r rL+++lL+l+ri+ +
CP002056_0 262 ----------NAALENVLHGVDRATRLVEQLLTLARIDPE 291

CP002056_0877: domain 1 of 1, from 277 to 343: score 60.2, E = 7e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +la++sH++RTPLt+I+g+a +L+ ++l++eq+
CP002056_0 277 IQNALLASISHDMRTPLTSILGAATTLQQ---------PNLNAEQT- 313

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++++ i +++++l + +++L l r+e+
CP002056_0 314 ----------AQLTALIASQSRYLASTTENILSLIRLESH 343

CP002056_2523: domain 1 of 1, from 131 to 188: score 59.3, E = 1.2e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a e+l+nl+HE+R+PL ++rg+a+lL+ el+++ +
CP002056_2 131 ANAELLRNLAHEIRNPLGGLRGAAQLLEH----------ELPSPSL- 166

peLRledpeyreyletilreaerllrLindlL<-*
rey+++i++ea+rl++L ++lL
CP002056_2 167 ----------REYTQVIIKEADRLQSLMDRLL 188

CP002056_0447: domain 1 of 1, from 233 to 298: score 53.8, E = 4.4e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+ fla+++H+LRTPLta+++ +el+l e ++ +
CP002056_0 233 AQKAFLADAAHQLRTPLTALQTESELALL----------EPHPKSL- 268

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
le++ r+a r +L n+lL ++r++ +
CP002056_0 269 ----------NTTLERLNRSASRAAKLANQLLAIARADPN 298

CP002056_1657: domain 1 of 1, from 145 to 208: score 51.8, E = 1.7e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++++l +sHELR PL+ ++ ++ l++ ++++
CP002056_1 145 SQTRLLHQVSHELRSPLARLQIAVGLARQ-----------QPDKL-- 178

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ l +i+re+ r+++L+ +lL lsr+e+g
CP002056_1 179 ----------ESSLMRIERESVRMDDLVGELLALSRLESG 208

CP002056_1894: domain 1 of 1, from 347 to 413: score 50.5, E = 3.9e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+e++a++sHE RTPL +r a++Ll+ +++ see
CP002056_1 347 VVGEMAAAMSHEVRTPLGILRSSAQVLLR--------EPNISEEG-- 383

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e i++e+erl++L++ l d +r + +
CP002056_1 384 ----------HEVCGFIISETERLNKLVSALIDSARPRLP 413

CP002056_0609: domain 1 of 1, from 242 to 307: score 50.3, E = 4.3e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++ flan++H+L+TPL++++ ae++l+ e + +
CP002056_0 242 ERRHFLANAAHQLKTPLAGLKIQAEAALR----------EDDLASI- 277

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +l+ i ++ l rL n+lL l+r+e +
CP002056_0 278 ----------QHALKQISAGSDNLARLANQLLSLARAEPE 307

CP002056_2016: domain 1 of 1, from 256 to 321: score 48.3, E = 1.6e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ + +l HEL+ P+taI++ +el+ +++e++
CP002056_2 256 YIQDSVQHLTHELKSPITAIQASLELISP----------SMPPETQ- 291

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +l i+ +++r + +i+++L l+ +e++
CP002056_2 292 ----------AHFLAQIKTQSNRVQTIIQNMLGLATLEHQ 321

CP002056_0214: domain 1 of 1, from 488 to 560: score 47.4, E = 3e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a +e ++ l+HE+++PLt I++ ae + +l l + ++++e +
CP002056_0 488 AWGEVARRLAHEIKNPLTPIQLSAERMSHKL---LSKLNAADAEML- 530

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ +eti ++++ + r++n++ d++r ++
CP002056_0 531 ----------KRSTETIVNQVDAMKRMVNEFSDYARSPTP 560

CP002056_1810: domain 1 of 1, from 213 to 278: score 45.2, E = 1.3e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a+ f+a+++HELRTPLta+++ ++l ++ ++ +
CP002056_1 213 AQHAFIADAAHELRTPLTALKLQLQLTER---------ATSDVIR-- 248

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + ++ + ++r +L+ +lL+l+r e+
CP002056_1 249 ----------EVGFVKLNERLDRSIHLVKQLLTLARSESK 278

CP002056_2111: domain 1 of 1, from 229 to 290: score 44.9, E = 1.5e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++ la++sH++RTPL+ +r+ +e+L + e
CP002056_2 229 ERTLILAGVSHDIRTPLARLRLSVEMLPD-------------EGC-- 260

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + +++++ ++++i ++Ld+ + +g
CP002056_2 261 ----------GSLKNGMIQDIADMDNIIHQFLDFVKGVEG 290

CP002056_2427: domain 1 of 1, from 270 to 321: score 36.3, E = 4.2e-10
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++ ++ +l+H +R+PL++Ir++a+++ + +e ++e+
CP002056_2 270 AQGLLVPMLAHNIRNPLASIRATAQVMDD---------PEHDAET-- 305

peLRledpeyreyletilreaerllr<-*
r l+ i++ ++rl+r
CP002056_2 306 ----------RLSLRGIIDTVDRLER 321

CP002056_1653: domain 1 of 1, from 276 to 346: score 34.7, E = 1.2e-09
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
s+ +++++HEL++PL+aI++y+e++l ++ +++ ++e +
CP002056_1 276 VASQTVSAIAHELNQPLAAISAYSEVALH-----ALNSSTFNPENL- 316

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +le + +a+r + + +lL + + ++
CP002056_1 317 ----------KHALEGAVAQAQRAGKSLHELLAFMQKGEL 346


Histogram of all scores:
score obs exp (one = represents 10 sequences)
----- --- ---
-15 6 0|=
-14 9 0|=
-13 44 2|*====
-12 129 63|======*======
-11 260 327|========================== *
-10 488 607|================================================= *
-9 540 627|====================================================== *
-8 455 469|==============================================*
-7 347 296|=============================*=====
-6 208 170|================*====
-5 113 93|=========*==
-4 64 50|====*==
-3 39 26|==*=
-2 16 13|=*
-1 8 7|*
0 4 3|*
1 0 1|*
2 6 1|*
3 0 0|
4 2 0|=
> 5 26 -|===


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 150.2389
P(chi-square) = 1.332e-26

Total sequences searched: 2764

Whole sequence top hits:
tophits_s report:
Total hits: 23
Satisfying E cutoff: 23
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 23
Satisfying E cutoff: 23
Total memory: 30K


Acknowledgements:

This research is funded by:

Developed by: