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Classification of phyla is from NCBI page
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Data for CT573213  

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hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: CT573213.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
CT573213_4101 CDS_4560228-4562681 90.9 3.5e-25 1
CT573213_6301 CDS_7023612-7019590 84.8 1.8e-23 1
CT573213_0656 CDS_732292-733824 83.8 3.4e-23 1
CT573213_5764 CDS_6410197-6411966 82.8 6.6e-23 1
CT573213_0667 CDS_751001-749055 80.8 2.4e-22 1
CT573213_1239 CDS_1373512-1375368 77.4 2.3e-21 1
CT573213_6260 CDS_6969175-6965060 76.7 3.7e-21 1
CT573213_1579 CDS_1749473-1748346 73.4 3e-20 1
CT573213_5092 CDS_5651512-5650367 71.5 1e-19 1
CT573213_3735 CDS_4098912-4097353 65.5 5.3e-18 1
CT573213_5182 CDS_5755726-5758368 59.9 2.1e-16 1
CT573213_0935 CDS_1030946-1032340 58.5 5.2e-16 1
CT573213_3956 CDS_4350754-4349519 57.7 8.6e-16 2
CT573213_4901 CDS_5435894-5437609 57.0 1.4e-15 1
CT573213_5696 CDS_6318347-6316767 52.9 2e-14 1
CT573213_6208 CDS_6915110-6916507 50.2 1.2e-13 1
CT573213_0636 CDS_714278-715960 49.6 1.7e-13 1
CT573213_1794 CDS_1997658-1999247 49.6 1.8e-13 1
CT573213_1300 CDS_1448826-1450460 33.1 8e-09 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CT573213_4101 1/1 319 384 .. 1 87 [] 90.9 3.5e-25
CT573213_6301 1/1 904 972 .. 1 87 [] 84.8 1.8e-23
CT573213_0656 1/1 261 327 .. 1 87 [] 83.8 3.4e-23
CT573213_5764 1/1 123 188 .. 1 87 [] 82.8 6.6e-23
CT573213_0667 1/1 353 420 .. 1 87 [] 80.8 2.4e-22
CT573213_1239 1/1 243 311 .. 1 87 [] 77.4 2.3e-21
CT573213_6260 1/1 823 891 .. 1 87 [] 76.7 3.7e-21
CT573213_1579 1/1 145 212 .. 1 87 [] 73.4 3e-20
CT573213_5092 1/1 157 225 .. 1 87 [] 71.5 1e-19
CT573213_3735 1/1 250 316 .. 1 87 [] 65.5 5.3e-18
CT573213_5182 1/1 633 701 .. 1 87 [] 59.9 2.1e-16
CT573213_0935 1/1 141 207 .. 1 87 [] 58.5 5.2e-16
CT573213_4901 1/1 232 296 .. 1 87 [] 57.0 1.4e-15
CT573213_3956 2/2 232 297 .. 1 87 [] 56.6 1.7e-15
CT573213_5696 1/1 253 321 .. 1 87 [] 52.9 2e-14
CT573213_6208 1/1 247 313 .. 1 87 [] 50.2 1.2e-13
CT573213_0636 1/1 277 345 .. 1 87 [] 49.6 1.7e-13
CT573213_1794 1/1 239 311 .. 1 87 [] 49.6 1.8e-13
CT573213_1300 1/1 255 319 .. 1 87 [] 33.1 8e-09

Alignments of top-scoring domains:
CT573213_4101: domain 1 of 1, from 319 to 384: score 90.9, E = 3.5e-25
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks fla++sHE+RTP++a++g++ lLl+ + l+++q
CT573213_4 319 AKSAFLATISHEIRTPMNAVIGMSGLLLD---------SRLDADQ-- 354

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r ++e+++++a+ ll Lind+Ld+s+ieag
CT573213_4 355 ----------RHLTEVVHDSAHALLLLINDILDFSKIEAG 384

CT573213_6301: domain 1 of 1, from 904 to 972: score 84.8, E = 1.8e-23
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
kseflan+sHELRTPL++++ +a lL +ls++q
CT573213_6 904 YKSEFLANMSHELRTPLNSLLILARLLAQ------NPTRNLSPKQ-- 942

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
ey ++i++++ ll+Lind+Ldls+ eag
CT573213_6 943 ----------VEYAHVIHSAGSDLLQLINDILDLSKVEAG 972

CT573213_0656: domain 1 of 1, from 261 to 327: score 83.8, E = 3.4e-23
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++f+a +sHELRTPLt+Irgya+lL++ + +++++
CT573213_0 261 QVRRFAAEASHELRTPLTSIRGYADLLRA---------GMVPADEA- 297

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++l++i++ea r+ +L++dlL l+ ++++
CT573213_0 298 ----------DQALRRIQQEAARMGDLVDDLLYLAHLDEQ 327

CT573213_5764: domain 1 of 1, from 123 to 188: score 82.8, E = 6.6e-23
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
ak+e++a l HELRTPL+a++g+a+lL+ ++l+++
CT573213_5 123 AKDELIARLGHELRTPLNAMLGFAQLLEL---------EPLTPDL-- 158

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ +e+i+ ++++++Li+d+Ldl+r++ag
CT573213_5 159 ----------HDDVERIITGGRHMQALIDDVLDLARLRAG 188

CT573213_0667: domain 1 of 1, from 353 to 420: score 80.8, E = 2.4e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++fla++sHELRTPL+aI+gyael ++ +++ +++
CT573213_0 353 RMRQFLADVSHELRTPLAAISGYAELTRR-------TREPVPPDV-- 390

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +++++e+ r+ +L++dlL l+r+++g
CT573213_0 391 ----------TYAMSRVESESARMTALVSDLLLLARLDSG 420

CT573213_1239: domain 1 of 1, from 243 to 311: score 77.4, E = 2.3e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
ak++fl+++sHELR P+++++g+a lLl+ + + l++eq
CT573213_1 243 AKTRFLRSVSHELRAPVNSVLGLARLLLD------PAGDSLTDEQ-- 281

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+ +e il +++ ll L+ndlLdls++e+g
CT573213_1 282 ----------RRQVELILASTKDLLTLVNDLLDLSKAESG 311

CT573213_6260: domain 1 of 1, from 823 to 891: score 76.7, E = 3.7e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k+eflan+sHELRTPL++++ +a+lL + d +ls +q+
CT573213_6 823 YKTEFLANMSHELRTPLNSLLILAKLLAD------NPDRNLSRKQI- 862

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ eti++++ ll Lind+Ldls+ eag
CT573213_6 863 -----------DFAETIHSAGSELLGLINDILDLSKVEAG 891

CT573213_1579: domain 1 of 1, from 145 to 212: score 73.4, E = 3e-20
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++e++a +sH+LRTPL++Ir++ae+ +++l ++e++
CT573213_1 145 SRRELVAWISHDLRTPLAGIRAMAEAFQDGL--------ITDPETT- 182

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+y +++l eaerl +++dl +l+r++ag
CT573213_1 183 ----------DRYHRRVLTEAERLTGMVDDLFELARLQAG 212

CT573213_5092: domain 1 of 1, from 157 to 225: score 71.5, E = 1e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ +++a+++HELR PLt+++g++ +Ll+ +++ ++eq+
CT573213_5 157 NRADLVATVAHELRSPLTSVKGFTATLLA-------KWDRFTDEQK- 195

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +l+t+ +a+r rL+ ++Ld sri++g
CT573213_5 196 ----------KLMLNTVNTDADRVTRLLAEVLDVSRIDSG 225

CT573213_3735: domain 1 of 1, from 250 to 316: score 65.5, E = 5.3e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ + f+a++ HELRTPLt++r+ +el+ + + +s+ q+
CT573213_3 250 RDRAFVADAGHELRTPLTVLRAELELADR---------PGRSARQL- 286

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
re+++t+ +e++rl rL + lL+l+r++ g
CT573213_3 287 ----------REAIHTAAEETDRLIRLAESLLTLARMDGG 316

CT573213_5182: domain 1 of 1, from 633 to 701: score 59.9, E = 2.1e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ +l ++sH+LRTPL+a ++++ L ++ ls ++r
CT573213_5 633 VRAALLTAVSHDLRTPLAAAKAAVTGLHS-------TEAVLSRDER- 671

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e+l t++++++rl rL+++lLd+sr++ag
CT573213_5 672 ----------DELLATAEESLDRLTRLVENLLDMSRLQAG 701

CT573213_0935: domain 1 of 1, from 141 to 207: score 58.5, E = 5.2e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++f+an+sHEL+TP+ a+ +ae+ + + ++ +
CT573213_0 141 VRRDFVANVSHELKTPVGALHVLAEAVAA---------ASEDPVAV- 177

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r++ +++ +e+ rl rL++++ dlsr++
CT573213_0 178 ----------RRFASRMTHESARLARLVQEIIDLSRLQGA 207

CT573213_4901: domain 1 of 1, from 232 to 296: score 57.0, E = 1.4e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++ fla++sH++RTPLta+r+ +elL+ ++d ++ +e
CT573213_4 232 SQRHFLADVSHQIRTPLTAMRLRLELLEQDVD------ATVAAEV-- 270

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
l e++rl+r+++ lL sr+e+
CT573213_4 271 --------------AGTLVEVHRLSRMVDGLLAVSRAEHA 296

CT573213_3956: domain 2 of 2, from 232 to 297: score 56.6, E = 1.7e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++efl+++sHELRTPL+a+r+ +e+ l+ ++++ +
CT573213_3 232 VQREFLSDASHELRTPLAAMRAELEVSLT----------HRGAAD-- 266

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+r +++ +++rl+rL dlL l+r e
CT573213_3 267 ---------WRAVAGRLHTDTRRLERLTGDLLVLARSEDL 297

CT573213_5696: domain 1 of 1, from 253 to 321: score 52.9, E = 2e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+s+++a++sHE+RTPLt+Irg++ ++++ ++ ls+ q+
CT573213_5 253 IRSDLVATVSHEFRTPLTGIRGNLLTIKR-------RRNRLSDAQL- 291

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++l+ + + ++rl+rL++++L+ + +
CT573213_5 292 ----------DDLLDAAVNYSDRLSRLLENMLTAATATGT 321

CT573213_6208: domain 1 of 1, from 247 to 313: score 50.2, E = 1.2e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a +++++ l+HELRTPLt+I g+a lL +t+l+++
CT573213_6 247 AEQRLTSELAHELRTPLTTIHGAAYLLAL--------RTDLDDQA-- 283

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
re + i++++ ++++ i+ lLdl+r ++
CT573213_6 284 ----------REDVALIKNSSASMSNTISVLLDLARRHSQ 313

CT573213_0636: domain 1 of 1, from 277 to 345: score 49.6, E = 1.7e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++f+ +sH+L PL + +++lL++++ +++ +e
CT573213_0 277 DLEQFAYVASHDLQEPLRKVASFCQLLERRY-------GDKLDERG- 315

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+y+ + + a+r+++LindlL +sr +
CT573213_0 316 ----------TQYIAFAVDGAKRMQQLINDLLAFSRVGRS 345

CT573213_1794: domain 1 of 1, from 239 to 311: score 49.6, E = 1.8e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++++ ++sHELRTPLt++r+++elLl+ +e+++ +l
CT573213_1 239 RQRQLVDDASHELRTPLTSLRTNIELLLR---------AEANPHRAL 276

peL.RledpeyreyletilreaerllrLindlLdlsrieag<-*
p+++R + +l+ ++ + + l+ L+++l +l+r e +
CT573213_1 277 PAAdR------AALLRDVDAQMRELSGLVSELVELARDEVP 311

CT573213_1300: domain 1 of 1, from 255 to 319: score 33.1, E = 8e-09
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++ ++ + sH+LR+PL a+r+ ++L l++e
CT573213_1 255 RQRALIDDTSHQLRNPLMAMRLRMDMLAG----------SLPDEA-- 289

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+ ++ +a rl+ L++ ++ l+ ++a
CT573213_1 290 ----------RDTYASMVAQAGRLQVLLDGMRALAVADAA 319


Histogram of all scores:
score obs exp (one = represents 22 sequences)
----- --- ---
-16 1 0|=
-15 3 0|=
-14 44 0|==
-13 176 5|*=======
-12 411 153|======*============
-11 715 795|================================= *
-10 1084 1475|================================================== *
-9 1258 1524|==========================================================*
-8 1059 1141|================================================= *
-7 827 719|================================*=====
-6 504 413|==================*====
-5 262 227|==========*=
-4 163 121|=====*==
-3 77 64|==*=
-2 38 33|=*
-1 41 17|*=
0 12 9|*
1 7 4|*
2 4 2|*
3 1 1|*
> 4 24 -|==


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 6492.3481
P(chi-square) = 0

Total sequences searched: 6723

Whole sequence top hits:
tophits_s report:
Total hits: 19
Satisfying E cutoff: 19
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 19
Satisfying E cutoff: 19
Total memory: 28K


Acknowledgements:

This research is funded by:

Developed by: