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Thermotogae
Classification of phyla is from NCBI page
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106 projects found  

2 accessions found for Mycobacterium abscessus ATCC 19977  

Data for CU458896  

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hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: CU458896.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
CU458896_2560 CDS_2627028-2628440 81.3 1.3e-22 1
CU458896_1703 CDS_1751747-1752763 77.1 2e-21 1
CU458896_0669 CDS_676921-678498 76.9 2.3e-21 1
CU458896_3224 CDS_3289926-3287419 68.5 5.3e-19 1
CU458896_3562 CDS_3641103-3639373 65.8 3.2e-18 1
CU458896_4019 CDS_4094954-4093473 65.5 4e-18 1
CU458896_1064 CDS_1090384-1091946 55.8 2.2e-15 1
CU458896_0944 CDS_964119-962707 49.8 1.1e-13 1
CU458896_1907 CDS_1927619-1928908 45.6 1.7e-12 1
CU458896_3313 CDS_3386749-3387885 37.8 2.8e-10 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CU458896_2560 1/1 238 305 .. 1 87 [] 81.3 1.3e-22
CU458896_1703 1/1 118 182 .. 1 87 [] 77.1 2e-21
CU458896_0669 1/1 270 334 .. 1 87 [] 76.9 2.3e-21
CU458896_3224 1/1 610 678 .. 1 87 [] 68.5 5.3e-19
CU458896_3562 1/1 291 358 .. 1 87 [] 65.8 3.2e-18
CU458896_4019 1/1 156 222 .. 1 87 [] 65.5 4e-18
CU458896_1064 1/1 250 322 .. 1 87 [] 55.8 2.2e-15
CU458896_0944 1/1 255 321 .. 1 87 [] 49.8 1.1e-13
CU458896_1907 1/1 213 279 .. 1 87 [] 45.6 1.7e-12
CU458896_3313 1/1 143 193 .. 1 73 [. 37.8 2.8e-10

Alignments of top-scoring domains:
CU458896_2560: domain 1 of 1, from 238 to 305: score 81.3, E = 1.3e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++f+a++sHELRTPL+aI+gyael++++ ++l+ +
CU458896_2 238 RVRQFVADASHELRTPLAAISGYAELARRNH-------DALPTDV-- 275

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + +++++ea r+ +L++dlL l+r+++g
CU458896_2 276 ----------AHAMSRVQSEAARMTELVEDLLLLARLDSG 305

CU458896_1703: domain 1 of 1, from 118 to 182: score 77.1, E = 2e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++e++ n+sHELRTP+ta+++ +e + +++ +e ++++
CU458896_1 118 YRRELVGNVSHELRTPITALQAVLENIVDGV-------AEPDPQT-- 155

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
l+t+l ++erl rL++dlLdls++e+g
CU458896_1 156 -------------LKTALAQTERLGRLVDDLLDLSKLENG 182

CU458896_0669: domain 1 of 1, from 270 to 334: score 76.9, E = 2.3e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+ ++sHELRTPLt+Irgyael + +++++ +
CU458896_0 270 RMRRFITDASHELRTPLTTIRGYAELYRQ---------GAATDTE-- 305

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
l +i+ e+ r+ +L++dlL l+r++a
CU458896_0 306 -----------LVLGRIEGESTRMGQLVEDLLLLARLDAH 334

CU458896_3224: domain 1 of 1, from 610 to 678: score 68.5, E = 5.3e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +l+++sH+LRTPL+a++++++ L+ d e s+e++
CU458896_3 610 LRRALLSAVSHDLRTPLAAVKAAVSSLRS-------PDIEFSPEDT- 648

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e+l t++++a++l +L+ +lLd sr+ ag
CU458896_3 649 ----------AELLATVEESADQLTALVGNLLDSSRLAAG 678

CU458896_3562: domain 1 of 1, from 291 to 358: score 65.8, E = 3.2e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++f++++sHELRTPLt++r++a+l+ + ++el++
CU458896_3 291 LQRRFTSDVSHELRTPLTTVRMAADLIYD-------NREELDPAL-- 328

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ e + +e++r + L+ dlL++sr +ag
CU458896_3 329 ----------QRSAELMVNELDRFETLLADLLEISRHDAG 358

CU458896_4019: domain 1 of 1, from 156 to 222: score 65.5, E = 4e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++f+an+sHEL+TP+ a+ +ae+Lle + ++e++
CU458896_4 156 TRRDFVANVSHELKTPVGAMGVLAEALLE---------SSDDPETV- 192

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r + e +l e++rl +++ +l lsr++
CU458896_4 193 ----------RHFGEQVLAESRRLGNMVTELIALSRLQGA 222

CU458896_1064: domain 1 of 1, from 250 to 322: score 55.8, E = 2.2e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkv.lagdtelseeqr
++ +++ ++ HELRTPLt++r+++elL + ++g + l++e++
CU458896_1 250 RQARLVTDAGHELRTPLTSLRTNTELLMA----AmQPGAPRLPDEEM 292

lpeLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + + ++ ++e l+ L+ dl dl+r +
CU458896_1 293 -----------QALQQDVIAQIEELSTLVGDLVDLARGDGA 322

CU458896_0944: domain 1 of 1, from 255 to 321: score 49.8, E = 1.1e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++f+a +sHELRTPLta+r+++e+L + +ls++qr
CU458896_0 255 SARDFAAVASHELRTPLTAMRTNLEVLST---------LNLSDDQR- 291

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e++e +r r ++ ++ l l++ +
CU458896_0 292 ----------EEIIEETIRTQSRVEATLSALERLAQGQLT 321

CU458896_1907: domain 1 of 1, from 213 to 279: score 45.6, E = 1.7e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a ++f+a+++HELRTPLta+r+ +++L++ ++ls ++r
CU458896_1 213 AARDFAASAAHELRTPLTAMRADLDTLRA---------HDLSGDER- 249

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e + ++r+ +r ++ i l +l+ +
CU458896_1 250 ----------VEVIGDLQRAQRRVEATITALGQLASGDLA 279

CU458896_3313: domain 1 of 1, from 143 to 193: score 37.8, E = 2.8e-10
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++++la+l+HE+RTP++++ +y e+ ++ + + +q
CU458896_3 143 ARRQMLADLAHEIRTPVAVLEAYMEAVED---------GVQQLDQ-- 178

peLRledpeyreyletilreaerllr<-*
+ + t++++++rl r
CU458896_3 179 -----------QTVATLRDQTRRLTR 193


Histogram of all scores:
score obs exp (one = represents 17 sequences)
----- --- ---
-15 1 0|=
-14 10 0|=
-13 53 3|*===
-12 253 112|======*========
-11 472 583|============================ *
-10 853 1081|=================================================== *
-9 989 1117|==========================================================*
-8 849 836|=================================================*
-7 600 527|==============================*=====
-6 365 303|=================*====
-5 215 166|=========*===
-4 104 89|=====*=
-3 60 47|==*=
-2 39 24|=*=
-1 24 12|*=
0 11 6|*
1 2 3|*
2 6 1|*
3 2 0|=
4 1 0|=
> 5 11 -|=


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 323.5838
P(chi-square) = 0

Total sequences searched: 4920

Whole sequence top hits:
tophits_s report:
Total hits: 10
Satisfying E cutoff: 10
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 10
Satisfying E cutoff: 10
Total memory: 24K


Acknowledgements:

This research is funded by:

Developed by: