Acidobacteria Actinobacteria Alphaproteobacteria
Aquificae Bacteroidetes/Chlorobi Betaproteobacteria
Chlamydiae/Verrucomicrobia Chloroflexi Cyanobacteria
Deinococcus-Thermus Deltaproteobacteria Epsilonproteobacteria
Firmicutes Fusobacteria Gammaproteobacteria
Other Bacteria Planctomycetes Spirochaetes
Thermotogae
Classification of phyla is from NCBI page
Search:
264 projects found  

1 accessions found for Escherichia coli 55989  

Data for CU928145  

Available Atlases
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hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: CU928145.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
CU928145_0393 CDS_443054-444349 91.0 2.4e-25 1
CU928145_2616 CDS_2716755-2720348 81.6 1.1e-22 1
CU928145_2428 CDS_2533288-2530487 80.6 2.1e-22 1
CU928145_1075 CDS_1164845-1162101 79.2 5.1e-22 1
CU928145_3550 CDS_3710271-3707935 78.9 6.3e-22 1
CU928145_2791 CDS_2914317-2912890 75.4 6.2e-21 1
CU928145_2292 CDS_2392906-2394309 69.8 2.4e-19 1
CU928145_4276 CDS_4486727-4485354 66.6 1.9e-18 1
CU928145_4915 CDS_5148696-5150120 62.4 2.9e-17 1
CU928145_4364 CDS_4591785-4593161 61.5 5.3e-17 1
CU928145_0545 CDS_611340-609880 61.0 7.3e-17 1
CU928145_3812 CDS_3970393-3968993 60.8 8.2e-17 1
CU928145_4232 CDS_4439999-4438950 59.7 1.8e-16 1
CU928145_3367 CDS_3520574-3521923 59.6 1.8e-16 1
CU928145_0660 CDS_740146-737462 59.6 1.8e-16 1
CU928145_3827 CDS_3987467-3988948 59.2 2.4e-16 1
CU928145_3723 CDS_3871197-3869845 55.0 3.7e-15 1
CU928145_2153 CDS_2227177-2225819 52.3 2.1e-14 1
CU928145_4468 CDS_4717521-4716430 45.0 2.5e-12 1
CU928145_1738 CDS_1831797-1833098 42.4 1.4e-11 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CU928145_0393 1/1 203 269 .. 1 87 [] 91.0 2.4e-25
CU928145_2616 1/1 711 777 .. 1 87 [] 81.6 1.1e-22
CU928145_2428 1/1 453 518 .. 1 87 [] 80.6 2.1e-22
CU928145_1075 1/1 443 508 .. 1 87 [] 79.2 5.1e-22
CU928145_3550 1/1 282 347 .. 1 87 [] 78.9 6.3e-22
CU928145_2791 1/1 249 317 .. 1 87 [] 75.4 6.2e-21
CU928145_2292 1/1 240 304 .. 1 87 [] 69.8 2.4e-19
CU928145_4276 1/1 238 300 .. 1 87 [] 66.6 1.9e-18
CU928145_4915 1/1 255 320 .. 1 87 [] 62.4 2.9e-17
CU928145_4364 1/1 237 303 .. 1 87 [] 61.5 5.3e-17
CU928145_0545 1/1 265 331 .. 1 87 [] 61.0 7.3e-17
CU928145_3812 1/1 247 313 .. 1 87 [] 60.8 8.2e-17
CU928145_4232 1/1 129 186 .. 1 79 [. 59.7 1.8e-16
CU928145_3367 1/1 236 302 .. 1 87 [] 59.6 1.8e-16
CU928145_0660 1/1 663 730 .. 1 87 [] 59.6 1.8e-16
CU928145_3827 1/1 262 328 .. 1 87 [] 59.2 2.4e-16
CU928145_3723 1/1 233 293 .. 1 87 [] 55.0 3.7e-15
CU928145_2153 1/1 235 301 .. 1 87 [] 52.3 2.1e-14
CU928145_4468 1/1 142 202 .. 1 87 [] 45.0 2.5e-12
CU928145_1738 1/1 211 271 .. 1 87 [] 42.4 1.4e-11

Alignments of top-scoring domains:
CU928145_0393: domain 1 of 1, from 203 to 269: score 91.0, E = 2.4e-25
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++ f+an+sHELRTPLt+++gy+e++ e ++l r
CU928145_0 203 ARRNFFANVSHELRTPLTVLQGYLEMMDE---------QPLEGAVR- 239

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l+t++++++r++ L+ +lL+ls+iea
CU928145_0 240 ----------EKALHTMREQTQRMEGLVKQLLTLSKIEAA 269

CU928145_2616: domain 1 of 1, from 711 to 777: score 81.6, E = 1.1e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks+fla++sHE+RTP+++I+g++elL + ls eqr
CU928145_2 711 AKSQFLATMSHEIRTPISSIMGFLELLSG---------SGLSKEQR- 747

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e+++ ++ +++ll Li ++Ld +ie+g
CU928145_2 748 ----------VEAISLAYATGQSLLGLIGEILDVDKIESG 777

CU928145_2428: domain 1 of 1, from 453 to 518: score 80.6, E = 2.1e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ks fla++sHELRTPL +I+g+++lL++ el+
CU928145_2 453 SKSMFLATVSHELRTPLYGIIGNLDLLQT---------KELPKGV-- 488

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ + +++ ll++i+d+Ld+s+ie++
CU928145_2 489 ----------DRLVTAMNNSSSLLLKIISDILDFSKIESE 518

CU928145_1075: domain 1 of 1, from 443 to 508: score 79.2, E = 5.1e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks fla++sHE+RTPL +I+g+a+lL + + q
CU928145_1 443 AKSAFLAAMSHEIRTPLYGILGTAQLLAD---------NPTLNAQ-- 478

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+ l+ i +++e+ll ++nd+Ld+s ieag
CU928145_1 479 ----------RDDLRAITDSGESLLTILNDILDYSAIEAG 508

CU928145_3550: domain 1 of 1, from 282 to 347: score 78.9, E = 6.3e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k+ f++++sHELRTPL++I g++ +Ll+ tel++eq
CU928145_3 282 DKTTFISTISHELRTPLNGIVGLSRILLD---------TELTAEQ-- 317

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++yl+ti+ +a l ++ nd+ d+ ++e
CU928145_3 318 ----------EKYLKTIHVSAVTLGNIFNDIIDMDKMERR 347

CU928145_2791: domain 1 of 1, from 249 to 317: score 75.4, E = 6.2e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +fl++lsHEL+TPL+++r +elL +++ ++l++eq
CU928145_2 249 QRHQFLRHLSHELKTPLASMREGTELLADQV------VGPLTPEQ-- 287

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e +++++++++ l++Li++lLd+ r +a
CU928145_2 288 ----------KEVVSILDSSSRNLQKLIEQLLDYNRKQAD 317

CU928145_2292: domain 1 of 1, from 240 to 304: score 69.8, E = 2.4e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+a++sHELRTPL+++rg +e++++++ + ++e+
CU928145_2 240 MRRDFMADISHELRTPLAVLRGELEAIQDGV-------RKFTPET-- 277

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +++ e+ l +L++dl +ls ++g
CU928145_2 278 -------------VASLQAEVGTLTKLVDDLHQLSMSDEG 304

CU928145_4276: domain 1 of 1, from 238 to 300: score 66.6, E = 1.9e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++++l+++sHELRTPLt +++ + lL++ +++
CU928145_4 238 SQQRLLSDISHELRTPLTRLQLGTALLRR---------RSGESKE-- 273

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
le+i+ ea+rl+++indlL +sr ++
CU928145_4 274 -------------LERIETEAQRLDSMINDLLVMSRNQQK 300

CU928145_4915: domain 1 of 1, from 255 to 320: score 62.4, E = 2.9e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ + +l HEL+ PL+aIrg+ae+L+e ++ +e
CU928145_4 255 YIEQYVYALTHELKSPLAAIRGAAEILRE---------GPPPEVV-- 290

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++++ il + r+++L++ lL +r+e+
CU928145_4 291 ----------ARFTDNILTQNARMQALVETLLRQARLENR 320

CU928145_4364: domain 1 of 1, from 237 to 303: score 61.5, E = 5.3e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++ ++a+++HE+R+PL++I+g+a+ e +++++ e
CU928145_4 237 ALGHLAAGVAHEIRNPLSSIKGLAKYFAE--------RAPAGGEA-- 273

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ +++ +ea+rl+r +++lL+l + +
CU928145_4 274 ----------HQLAQVMAKEADRLNRVVSELLELVKPTHL 303

CU928145_0545: domain 1 of 1, from 265 to 331: score 61.0, E = 7.3e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++s f a+++HE+RTP+t +++ +e++l + +s +++
CU928145_0 265 RQSNFSADIAHEIRTPITNLITQTEIALS---------QSRSQKEL- 301

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ l + l+e+ r+ ++++d+L l++++++
CU928145_0 302 ----------EDVLYSNLEELTRMAKMVSDMLFLAQADNN 331

CU928145_3812: domain 1 of 1, from 247 to 313: score 60.8, E = 8.2e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+s+f ++++HELRTP++ +++ ++ +l+ e++ +
CU928145_3 247 KLSDFSSDIAHELRTPVSNLMMQTQFALA---------KERDVSH-- 282

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
yre+l l+e++rl+r+ +d+L l+r e+g
CU928145_3 283 ---------YREILFANLEELKRLSRMTSDMLFLARSEHG 313

CU928145_4232: domain 1 of 1, from 129 to 186: score 59.7, E = 1.8e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a ++++++l+HE+++PL ++rg+a+lL + +l+++ +
CU928145_4 129 AARDLVRGLAHEIKNPLGGLRGAAQLLSK----------ALPDPSL- 164

peLRledpeyreyletilreaerllrLindlL<-*
ey+++i+++a+rl++L+++lL
CU928145_4 165 ----------LEYTKVIIEQADRLRNLVDRLL 186

CU928145_3367: domain 1 of 1, from 236 to 302: score 59.6, E = 1.8e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++f+++++HELR PLta++ +e+++ ++ +++ r
CU928145_3 236 RERRFTSDAAHELRSPLTALKVQTEVAQL---------SDDDPQAR- 272

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l ++ ++r rL+++lL+lsr+++
CU928145_3 273 ----------KKALLQLHYGIDRATRLVDQLLTLSRLDSL 302

CU928145_0660: domain 1 of 1, from 663 to 730: score 59.6, E = 1.8e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +la+lsH+LRTPLt++ g ae+L +l + ++++
CU928145_0 663 IRNALLAALSHDLRTPLTVLFGQAEILTLDL-------ASEGSPH-- 700

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ + i++ + rL+n+lLd++ri++g
CU928145_0 701 ----------ARQASEIRQHVLNTTRLVNNLLDMARIQSG 730

CU928145_3827: domain 1 of 1, from 262 to 328: score 59.2, E = 2.4e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ f a+++HE+RTP+t + + +e++l ++++ ++
CU928145_3 262 RQANFSADIAHEIRTPITNLVTQTEIALS---------QDRTQREL- 298

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ l + l+e +r+ ++++d+L l++++++
CU928145_3 299 ----------EDVLYSSLEEYNRMTKMVSDMLFLAQADNN 328

CU928145_3723: domain 1 of 1, from 233 to 293: score 55.0, E = 3.7e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ ++a++sH+LRTPLt Ir+++e++ e ++
CU928145_3 233 DRTLLMAGVSHDLRTPLTRIRLATEMMSE---------QD------- 263

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ e+i +++e ++++i+++ d+ r +++
CU928145_3 264 ----------GYLAESINKDIEECNAIIEQFIDYLRTGQE 293

CU928145_2153: domain 1 of 1, from 235 to 301: score 52.3, E = 2.1e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++s+f+ +l+HELRTP++a++g ++ l +++s +
CU928145_2 235 RLSQFADDLAHELRTPINALLGQNQVTLS---------QTRSIAE-- 270

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
y++ + ++e+e ++rL +++L l+r++ +
CU928145_2 271 ---------YQKTIAGNIEELENISRLTENILFLARADKN 301

CU928145_4468: domain 1 of 1, from 142 to 202: score 45.0, E = 2.5e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ f+a+++HELRTPL+++r+++elL + t+
CU928145_4 142 NERLFTADVAHELRTPLAGVRLHLELLAK---------TH------- 172

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + + ++++ + +++lL+l+r+++
CU928145_4 173 ----------HIDVAPLVARLDQMMESVSQLLQLARAGQS 202

CU928145_1738: domain 1 of 1, from 211 to 271: score 42.4, E = 1.4e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+k +++ +++HELRTPL +r +e+ + ls+ +
CU928145_1 211 SKKQLIDGIAHELRTPLVRLRYRLEMSDN-----------LSAAE-- 244

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + r++ +l++Li++lL+++r++ +
CU928145_1 245 -------------SQALNRDISQLEALIEELLTYARLDRP 271


Histogram of all scores:
score obs exp (one = represents 16 sequences)
----- --- ---
-16 1 0|=
-15 3 0|=
-14 25 0|==
-13 79 3|*====
-12 233 108|======*========
-11 511 564|================================ *
-10 803 1047|=================================================== *
-9 897 1081|========================================================= *
-8 775 809|================================================= *
-7 561 510|===============================*====
-6 375 293|==================*=====
-5 204 161|==========*==
-4 105 86|=====*=
-3 69 45|==*==
-2 28 23|=*
-1 34 12|*==
0 14 6|*
1 8 3|*
2 12 1|*
3 2 0|=
4 2 0|=
> 5 22 -|==


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 338.1118
P(chi-square) = 0

Total sequences searched: 4919

Whole sequence top hits:
tophits_s report:
Total hits: 20
Satisfying E cutoff: 20
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 20
Satisfying E cutoff: 20
Total memory: 28K


Acknowledgements:

This research is funded by:

Developed by: