Acidobacteria Actinobacteria Alphaproteobacteria
Aquificae Bacteroidetes/Chlorobi Betaproteobacteria
Chlamydiae/Verrucomicrobia Chloroflexi Cyanobacteria
Deinococcus-Thermus Deltaproteobacteria Epsilonproteobacteria
Firmicutes Fusobacteria Gammaproteobacteria
Other Bacteria Planctomycetes Spirochaetes
Thermotogae
Classification of phyla is from NCBI page
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264 projects found  

2 accessions found for Escherichia coli S88  

Data for CU928161  

Available Atlases
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hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: CU928161.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
CU928161_2924 CDS_3001391-3004147 100.1 5.9e-28 1
CU928161_0373 CDS_421513-422808 91.0 2.3e-25 1
CU928161_2466 CDS_2541274-2544867 81.6 1e-22 1
CU928161_0967 CDS_1047006-1044274 80.7 1.8e-22 1
CU928161_2274 CDS_2351954-2349153 80.6 2.1e-22 1
CU928161_3446 CDS_3560407-3558071 78.9 6.2e-22 1
CU928161_2275 CDS_2352169-2353995 77.9 1.1e-21 1
CU928161_2620 CDS_2728485-2727058 75.4 6.1e-21 1
CU928161_2091 CDS_2159680-2161083 70.4 1.6e-19 1
CU928161_4170 CDS_4328601-4327228 66.6 1.9e-18 1
CU928161_4844 CDS_5027312-5028736 62.4 2.8e-17 1
CU928161_4260 CDS_4437000-4438376 61.5 5.2e-17 1
CU928161_0579 CDS_620383-618941 61.0 7.2e-17 1
CU928161_3269 CDS_3375539-3376888 60.7 9e-17 1
CU928161_4131 CDS_4288973-4287924 59.7 1.7e-16 1
CU928161_0697 CDS_746444-743760 59.6 1.8e-16 1
CU928161_3631 CDS_3736072-3734720 55.0 3.6e-15 1
CU928161_1946 CDS_1992604-1991246 52.3 2e-14 1
CU928161_4396 CDS_4593843-4592752 45.0 2.5e-12 1
CU928161_1596 CDS_1651745-1653046 42.4 1.4e-11 1
CU928161_3141 CDS_3246898-3248907 29.4 6.6e-08 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CU928161_2924 1/1 292 357 .. 1 87 [] 100.1 5.9e-28
CU928161_0373 1/1 203 269 .. 1 87 [] 91.0 2.3e-25
CU928161_2466 1/1 711 777 .. 1 87 [] 81.6 1e-22
CU928161_0967 1/1 443 508 .. 1 87 [] 80.7 1.8e-22
CU928161_2274 1/1 453 518 .. 1 87 [] 80.6 2.1e-22
CU928161_3446 1/1 282 347 .. 1 87 [] 78.9 6.2e-22
CU928161_2275 1/1 388 453 .. 1 87 [] 77.9 1.1e-21
CU928161_2620 1/1 249 317 .. 1 87 [] 75.4 6.1e-21
CU928161_2091 1/1 240 304 .. 1 87 [] 70.4 1.6e-19
CU928161_4170 1/1 238 300 .. 1 87 [] 66.6 1.9e-18
CU928161_4844 1/1 255 320 .. 1 87 [] 62.4 2.8e-17
CU928161_4260 1/1 237 303 .. 1 87 [] 61.5 5.2e-17
CU928161_0579 1/1 261 327 .. 1 87 [] 61.0 7.2e-17
CU928161_3269 1/1 236 302 .. 1 87 [] 60.7 9e-17
CU928161_4131 1/1 129 186 .. 1 79 [. 59.7 1.7e-16
CU928161_0697 1/1 663 730 .. 1 87 [] 59.6 1.8e-16
CU928161_3631 1/1 233 293 .. 1 87 [] 55.0 3.6e-15
CU928161_1946 1/1 235 301 .. 1 87 [] 52.3 2e-14
CU928161_4396 1/1 142 202 .. 1 87 [] 45.0 2.5e-12
CU928161_1596 1/1 211 271 .. 1 87 [] 42.4 1.4e-11
CU928161_3141 1/1 448 516 .. 1 87 [] 29.4 6.6e-08

Alignments of top-scoring domains:
CU928161_2924: domain 1 of 1, from 292 to 357: score 100.1, E = 5.9e-28
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
kseflan+sHELRTPL++++g++ l l+ tel++ q
CU928161_2 292 IKSEFLANMSHELRTPLNGVIGFTRLTLK---------TELTPTQ-- 327

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+ l+ti+r+a+ ll++ind+Ld+s++eag
CU928161_2 328 ----------RDHLNTIERSANNLLAIINDVLDFSKLEAG 357

CU928161_0373: domain 1 of 1, from 203 to 269: score 91.0, E = 2.3e-25
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++ f+an+sHELRTPLt+++gy+e++ e ++l r
CU928161_0 203 ARRNFFANVSHELRTPLTVLQGYLEMMDE---------QPLEGAVR- 239

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l+t++++++r++ L+ +lL+ls+iea
CU928161_0 240 ----------EKALHTMREQTQRMEGLVKQLLTLSKIEAA 269

CU928161_2466: domain 1 of 1, from 711 to 777: score 81.6, E = 1e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks+fla++sHE+RTP+++I+g++elL + ls eqr
CU928161_2 711 AKSQFLATMSHEIRTPISSIMGFLELLSG---------SGLSKEQR- 747

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e+++ ++ +++ll Li ++Ld +ie+g
CU928161_2 748 ----------VEAISLAYATGQSLLGLIGEILDVDKIESG 777

CU928161_0967: domain 1 of 1, from 443 to 508: score 80.7, E = 1.8e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks fla++sHE+RTPL +I+g+a+lL + ++ q
CU928161_0 443 AKSAFLAAMSHEIRTPLYGILGTAQLLAD---------NPALNAQ-- 478

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+ l+ i +++e+ll ++nd+Ld+s ieag
CU928161_0 479 ----------RDDLRAITDSGESLLTILNDILDYSAIEAG 508

CU928161_2274: domain 1 of 1, from 453 to 518: score 80.6, E = 2.1e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ks fla++sHELRTPL +I+g+++lL++ el+
CU928161_2 453 SKSMFLATVSHELRTPLYGIIGNLDLLQT---------KELPKGV-- 488

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ + +++ ll++i+d+Ld+s+ie++
CU928161_2 489 ----------DRLVTAMNNSSSLLLKIISDILDFSKIESE 518

CU928161_3446: domain 1 of 1, from 282 to 347: score 78.9, E = 6.2e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k+ f++++sHELRTPL++I g++ +Ll+ tel++eq
CU928161_3 282 DKTTFISTISHELRTPLNGIVGLSRILLD---------TELTAEQ-- 317

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++yl+ti+ +a l ++ nd+ d+ ++e
CU928161_3 318 ----------EKYLKTIHVSAVTLGNIFNDIIDMDKMERR 347

CU928161_2275: domain 1 of 1, from 388 to 453: score 77.9, E = 1.1e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++e++a+++HE R+PLtaIrgy+++L+ +++++ +
CU928161_2 388 TLGELMAGVAHEVRNPLTAIRGYVQILRQ---------QTRDPIH-- 423

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+eyl+++l+e++++++ i++lL++sr ++
CU928161_2 424 ----------QEYLSVVLKEIDSINKVIQQLLEFSRPRHS 453

CU928161_2620: domain 1 of 1, from 249 to 317: score 75.4, E = 6.1e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +fl++lsHEL+TPL+++r +elL +++ ++l++eq
CU928161_2 249 QRHQFLRHLSHELKTPLASMREGTELLADQV------VGPLTPEQ-- 287

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e +++++++++ l++Li++lLd+ r +a
CU928161_2 288 ----------KEVVSILDSSSRNLQKLIEQLLDYNRKQAD 317

CU928161_2091: domain 1 of 1, from 240 to 304: score 70.4, E = 1.6e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+a++sHELRTPL+++rg +e++++++ + ++e+
CU928161_2 240 MRRDFMADISHELRTPLAVLRGELEAIQDGV-------RKFTPET-- 277

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
l +++ e+ l +L++dl +ls ++g
CU928161_2 278 -------------LASLQAEVGTLTKLVDDLHQLSMSDEG 304

CU928161_4170: domain 1 of 1, from 238 to 300: score 66.6, E = 1.9e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++++l+++sHELRTPLt +++ + lL++ +++
CU928161_4 238 SQQRLLSDISHELRTPLTRLQLGTALLRR---------RSGESKE-- 273

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
le+i+ ea+rl+++indlL +sr ++
CU928161_4 274 -------------LERIETEAQRLDSMINDLLVMSRNQQK 300

CU928161_4844: domain 1 of 1, from 255 to 320: score 62.4, E = 2.8e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ + +l HEL+ PL+aIrg+ae+L+e ++ +e
CU928161_4 255 YIEQYVYALTHELKSPLAAIRGAAEILRE---------GPPPEVV-- 290

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++++ il + r+++L++ lL +r+e+
CU928161_4 291 ----------ARFTDNILTQNARMQALVETLLRQARLENR 320

CU928161_4260: domain 1 of 1, from 237 to 303: score 61.5, E = 5.2e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++ ++a+++HE+R+PL++I+g+a+ e +++++ e
CU928161_4 237 ALGHLAAGVAHEIRNPLSSIKGLAKYFAE--------RAPAGGEA-- 273

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ +++ +ea+rl+r +++lL+l + +
CU928161_4 274 ----------HQLAQVMAKEADRLNRVVSELLELVKPTHL 303

CU928161_0579: domain 1 of 1, from 261 to 327: score 61.0, E = 7.2e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++s f a+++HE+RTP+t +++ +e++l + +s +++
CU928161_0 261 RQSNFSADIAHEIRTPITNLITQTEIALS---------QSRSQKEL- 297

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ l + l+e+ r+ ++++d+L l++++++
CU928161_0 298 ----------EDVLYSNLEELTRMAKMVSDMLFLAQADNN 327

CU928161_3269: domain 1 of 1, from 236 to 302: score 60.7, E = 9e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++f+++++HELR PLta++ +e+++ ++ +++ r
CU928161_3 236 RERRFTSDAAHELRSPLTALKVQTEVAQL---------SDDDPQAR- 272

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l +++ ++r rL+++lL+lsr+++
CU928161_3 273 ----------KKALLQLHSGIDRATRLVDQLLTLSRLDSL 302

CU928161_4131: domain 1 of 1, from 129 to 186: score 59.7, E = 1.7e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a ++++++l+HE+++PL ++rg+a+lL + +l+++ +
CU928161_4 129 AARDLVRGLAHEIKNPLGGLRGAAQLLSK----------ALPDPSL- 164

peLRledpeyreyletilreaerllrLindlL<-*
ey+++i+++a+rl++L+++lL
CU928161_4 165 ----------LEYTKVIIEQADRLRNLVDRLL 186

CU928161_0697: domain 1 of 1, from 663 to 730: score 59.6, E = 1.8e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +la+lsH+LRTPLt++ g ae+L +l + ++++
CU928161_0 663 IRNALLAALSHDLRTPLTVLFGQAEILTLDL-------ASEGSPH-- 700

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ + i++ + rL+n+lLd++ri++g
CU928161_0 701 ----------ARQASEIRQHVLNTTRLVNNLLDMARIQSG 730

CU928161_3631: domain 1 of 1, from 233 to 293: score 55.0, E = 3.6e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ ++a++sH+LRTPLt Ir+++e++ e ++
CU928161_3 233 DRTLLMAGVSHDLRTPLTRIRLATEMMSE---------QD------- 263

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ e+i +++e ++++i+++ d+ r +++
CU928161_3 264 ----------GYLAESINKDIEECNAIIEQFIDYLRTGQE 293

CU928161_1946: domain 1 of 1, from 235 to 301: score 52.3, E = 2e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++s+f+ +l+HELRTP++a++g ++ l +++s +
CU928161_1 235 RLSQFADDLAHELRTPINALLGQNQVTLS---------QTRSIAE-- 270

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
y++ + ++e+e ++rL +++L l+r++ +
CU928161_1 271 ---------YQKTIAGNIEELENISRLTENILFLARADKN 301

CU928161_4396: domain 1 of 1, from 142 to 202: score 45.0, E = 2.5e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ f+a+++HELRTPL+++r+++elL + t+
CU928161_4 142 NERLFTADVAHELRTPLAGVRLHLELLAK---------TH------- 172

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + + ++++ + +++lL+l+r+++
CU928161_4 173 ----------HIDVAPLVARLDQMMESVSQLLQLARAGQS 202

CU928161_1596: domain 1 of 1, from 211 to 271: score 42.4, E = 1.4e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+k +++ +++HELRTPL +r +e+ + ls+ +
CU928161_1 211 SKKQLIDGIAHELRTPLVRLRYRLEMSDN-----------LSAAE-- 244

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + r++ +l++Li++lL+++r++ +
CU928161_1 245 -------------SQALNRDISQLEALIEELLTYARLDRP 271

CU928161_3141: domain 1 of 1, from 448 to 516: score 29.4, E = 6.6e-08
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ + +l+HE+++PL+a+++y+ ++++ a+++++ e+
CU928161_3 448 VVGQTMTTLAHEINQPLNALSMYLFTARR------AIEQTQKEQA-- 486

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+l +++ + r++++i+ l++++r +
CU928161_3 487 ----------SMMLGKAEGVISRIDAIIRSLRQFTRRAEL 516


Histogram of all scores:
score obs exp (one = represents 15 sequences)
----- --- ---
-16 1 0|=
-15 3 0|=
-14 22 0|==
-13 66 3|*====
-12 221 107|=======*=======
-11 502 556|================================== *
-10 829 1032|======================================================== *
-9 868 1066|==========================================================*
-8 774 798|==================================================== *
-7 570 503|=================================*====
-6 348 289|===================*====
-5 217 158|==========*====
-4 96 85|=====*=
-3 58 44|==*=
-2 36 23|=*=
-1 31 12|*==
0 16 6|*=
1 7 3|*
2 6 1|*
3 1 0|=
4 0 0|
> 5 24 -|==


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 299.9288
P(chi-square) = 0

Total sequences searched: 4847

Whole sequence top hits:
tophits_s report:
Total hits: 21
Satisfying E cutoff: 21
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 21
Satisfying E cutoff: 21
Total memory: 29K


Acknowledgements:

This research is funded by:

Developed by: