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Deinococcus-Thermus Deltaproteobacteria Epsilonproteobacteria
Firmicutes Fusobacteria Gammaproteobacteria
Other Bacteria Planctomycetes Spirochaetes
Thermotogae
Classification of phyla is from NCBI page
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264 projects found  

1 accessions found for Escherichia coli ED1a  

Data for CU928162  

Available Atlases
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hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: CU928162.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
CU928162_3160 CDS_3172450-3175206 100.1 6.2e-28 1
CU928162_0407 CDS_438875-440170 91.0 2.5e-25 1
CU928162_2757 CDS_2759117-2762710 81.6 1.1e-22 1
CU928162_1044 CDS_1090348-1087616 80.7 1.9e-22 1
CU928162_2625 CDS_2610213-2607412 80.6 2.2e-22 1
CU928162_3775 CDS_3795570-3793234 78.9 6.6e-22 1
CU928162_2919 CDS_2948106-2946679 75.4 6.4e-21 1
CU928162_2626 CDS_2610428-2612254 74.1 1.5e-20 1
CU928162_2373 CDS_2371901-2373304 70.4 1.6e-19 1
CU928162_4484 CDS_4556354-4554981 66.6 2e-18 1
CU928162_5119 CDS_5204291-5205715 62.4 3e-17 1
CU928162_0546 CDS_584955-583513 61.0 7.6e-17 1
CU928162_3592 CDS_3609122-3610471 60.7 9.6e-17 1
CU928162_4572 CDS_4661230-4662606 60.1 1.4e-16 1
CU928162_4443 CDS_4513046-4511997 59.7 1.8e-16 1
CU928162_0654 CDS_702020-699336 59.6 1.9e-16 1
CU928162_3958 CDS_3967954-3966602 55.0 3.8e-15 1
CU928162_2187 CDS_2157684-2156326 52.3 2.2e-14 1
CU928162_4700 CDS_4810045-4808954 45.0 2.6e-12 1
CU928162_1768 CDS_1765034-1766335 42.4 1.5e-11 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
CU928162_3160 1/1 292 357 .. 1 87 [] 100.1 6.2e-28
CU928162_0407 1/1 203 269 .. 1 87 [] 91.0 2.5e-25
CU928162_2757 1/1 711 777 .. 1 87 [] 81.6 1.1e-22
CU928162_1044 1/1 443 508 .. 1 87 [] 80.7 1.9e-22
CU928162_2625 1/1 453 518 .. 1 87 [] 80.6 2.2e-22
CU928162_3775 1/1 282 347 .. 1 87 [] 78.9 6.6e-22
CU928162_2919 1/1 249 317 .. 1 87 [] 75.4 6.4e-21
CU928162_2626 1/1 388 453 .. 1 87 [] 74.1 1.5e-20
CU928162_2373 1/1 240 304 .. 1 87 [] 70.4 1.6e-19
CU928162_4484 1/1 238 300 .. 1 87 [] 66.6 2e-18
CU928162_5119 1/1 255 320 .. 1 87 [] 62.4 3e-17
CU928162_0546 1/1 261 327 .. 1 87 [] 61.0 7.6e-17
CU928162_3592 1/1 236 302 .. 1 87 [] 60.7 9.6e-17
CU928162_4572 1/1 237 303 .. 1 87 [] 60.1 1.4e-16
CU928162_4443 1/1 129 186 .. 1 79 [. 59.7 1.8e-16
CU928162_0654 1/1 663 730 .. 1 87 [] 59.6 1.9e-16
CU928162_3958 1/1 233 293 .. 1 87 [] 55.0 3.8e-15
CU928162_2187 1/1 235 301 .. 1 87 [] 52.3 2.2e-14
CU928162_4700 1/1 142 202 .. 1 87 [] 45.0 2.6e-12
CU928162_1768 1/1 211 271 .. 1 87 [] 42.4 1.5e-11

Alignments of top-scoring domains:
CU928162_3160: domain 1 of 1, from 292 to 357: score 100.1, E = 6.2e-28
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
kseflan+sHELRTPL++++g++ l l+ tel++ q
CU928162_3 292 IKSEFLANMSHELRTPLNGVIGFTRLTLK---------TELTPTQ-- 327

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+ l+ti+r+a+ ll++ind+Ld+s++eag
CU928162_3 328 ----------RDHLNTIERSANNLLAIINDVLDFSKLEAG 357

CU928162_0407: domain 1 of 1, from 203 to 269: score 91.0, E = 2.5e-25
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++ f+an+sHELRTPLt+++gy+e++ e ++l r
CU928162_0 203 ARRNFFANVSHELRTPLTVLQGYLEMMDE---------QPLEGAVR- 239

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l+t++++++r++ L+ +lL+ls+iea
CU928162_0 240 ----------EKALHTMREQTQRMEGLVKQLLTLSKIEAA 269

CU928162_2757: domain 1 of 1, from 711 to 777: score 81.6, E = 1.1e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks+fla++sHE+RTP+++I+g++elL + ls eqr
CU928162_2 711 AKSQFLATMSHEIRTPISSIMGFLELLSG---------SGLSKEQR- 747

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e+++ ++ +++ll Li ++Ld +ie+g
CU928162_2 748 ----------VEAISLAYATGQSLLGLIGEILDVDKIESG 777

CU928162_1044: domain 1 of 1, from 443 to 508: score 80.7, E = 1.9e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks fla++sHE+RTPL +I+g+a+lL + ++ q
CU928162_1 443 AKSAFLAAMSHEIRTPLYGILGTAQLLAD---------NPALNAQ-- 478

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+ l+ i +++e+ll ++nd+Ld+s ieag
CU928162_1 479 ----------RDDLRAITDSGESLLTILNDILDYSAIEAG 508

CU928162_2625: domain 1 of 1, from 453 to 518: score 80.6, E = 2.2e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ks fla++sHELRTPL +I+g+++lL++ el+
CU928162_2 453 SKSMFLATVSHELRTPLYGIIGNLDLLQT---------KELPKGV-- 488

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ + +++ ll++i+d+Ld+s+ie++
CU928162_2 489 ----------DRLVTAMNNSSSLLLKIISDILDFSKIESE 518

CU928162_3775: domain 1 of 1, from 282 to 347: score 78.9, E = 6.6e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k+ f++++sHELRTPL++I g++ +Ll+ tel++eq
CU928162_3 282 DKTTFISTISHELRTPLNGIVGLSRILLD---------TELTAEQ-- 317

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++yl+ti+ +a l ++ nd+ d+ ++e
CU928162_3 318 ----------EKYLKTIHVSAVTLGNIFNDIIDMDKMERR 347

CU928162_2919: domain 1 of 1, from 249 to 317: score 75.4, E = 6.4e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +fl++lsHEL+TPL+++r +elL +++ ++l++eq
CU928162_2 249 QRHQFLRHLSHELKTPLASMREGTELLADQV------VGPLTPEQ-- 287

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e +++++++++ l++Li++lLd+ r +a
CU928162_2 288 ----------KEVVSILDSSSRNLQKLIEQLLDYNRKQAD 317

CU928162_2626: domain 1 of 1, from 388 to 453: score 74.1, E = 1.5e-20
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++e++a+++HE R+PLtaIrgy+++L +++++ +
CU928162_2 388 TLGELMAGVAHEVRNPLTAIRGYVQILHQ---------QTRDPIH-- 423

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+eyl+++l+e++++++ i++lL++sr ++
CU928162_2 424 ----------QEYLSVVLKEIDSINKVIQQLLEFSRPRHS 453

CU928162_2373: domain 1 of 1, from 240 to 304: score 70.4, E = 1.6e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+a++sHELRTPL+++rg +e++++++ + ++e+
CU928162_2 240 MRRDFMADISHELRTPLAVLRGELEAIQDGV-------RKFTPET-- 277

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
l +++ e+ l +L++dl +ls ++g
CU928162_2 278 -------------LASLQAEVGTLTKLVDDLHQLSMSDEG 304

CU928162_4484: domain 1 of 1, from 238 to 300: score 66.6, E = 2e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++++l+++sHELRTPLt +++ + lL++ +++
CU928162_4 238 SQQRLLSDISHELRTPLTRLQLGTALLRR---------RSGESKE-- 273

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
le+i+ ea+rl+++indlL +sr ++
CU928162_4 274 -------------LERIETEAQRLDSMINDLLVMSRNQQK 300

CU928162_5119: domain 1 of 1, from 255 to 320: score 62.4, E = 3e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ + +l HEL+ PL+aIrg+ae+L+e ++ +e
CU928162_5 255 YIEQYVYALTHELKSPLAAIRGAAEILRE---------GPPPEVV-- 290

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++++ il + r+++L++ lL +r+e+
CU928162_5 291 ----------ARFTDNILTQNARMQALVETLLRQARLENR 320

CU928162_0546: domain 1 of 1, from 261 to 327: score 61.0, E = 7.6e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++s f a+++HE+RTP+t +++ +e++l + +s +++
CU928162_0 261 RQSNFSADIAHEIRTPITNLITQTEIALS---------QSRSQKEL- 297

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ l + l+e+ r+ ++++d+L l++++++
CU928162_0 298 ----------EDVLYSNLEELTRMAKMVSDMLFLAQADNN 327

CU928162_3592: domain 1 of 1, from 236 to 302: score 60.7, E = 9.6e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++f+++++HELR PLta++ +e+++ ++ +++ r
CU928162_3 236 RERRFTSDAAHELRSPLTALKVQTEVAQL---------SDDDPQAR- 272

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l +++ ++r rL+++lL+lsr+++
CU928162_3 273 ----------KKALLQLHSGIDRATRLVDQLLTLSRLDSL 302

CU928162_4572: domain 1 of 1, from 237 to 303: score 60.1, E = 1.4e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++ ++a+++HE+R+PL++I+g+a+ e ++ ++ e
CU928162_4 237 ALGHLAAGVAHEIRNPLSSIKGLAKYFAE--------RASAGGEA-- 273

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ +++ +ea+rl+r +++lL+l + +
CU928162_4 274 ----------HQLAQVMAKEADRLNRVVSELLELVKPTHL 303

CU928162_4443: domain 1 of 1, from 129 to 186: score 59.7, E = 1.8e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a ++++++l+HE+++PL ++rg+a+lL + +l+++ +
CU928162_4 129 AARDLVRGLAHEIKNPLGGLRGAAQLLSK----------ALPDPSL- 164

peLRledpeyreyletilreaerllrLindlL<-*
ey+++i+++a+rl++L+++lL
CU928162_4 165 ----------LEYTKVIIEQADRLRNLVDRLL 186

CU928162_0654: domain 1 of 1, from 663 to 730: score 59.6, E = 1.9e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +la+lsH+LRTPLt++ g ae+L +l + ++++
CU928162_0 663 IRNALLAALSHDLRTPLTVLFGQAEILTLDL-------ASEGSPH-- 700

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ + i++ + rL+n+lLd++ri++g
CU928162_0 701 ----------ARQASEIRQHVLNTTRLVNNLLDMARIQSG 730

CU928162_3958: domain 1 of 1, from 233 to 293: score 55.0, E = 3.8e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ ++a++sH+LRTPLt Ir+++e++ e ++
CU928162_3 233 DRTLLMAGVSHDLRTPLTRIRLATEMMSE---------QD------- 263

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ e+i +++e ++++i+++ d+ r +++
CU928162_3 264 ----------GYLAESINKDIEECNAIIEQFIDYLRTGQE 293

CU928162_2187: domain 1 of 1, from 235 to 301: score 52.3, E = 2.2e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++s+f+ +l+HELRTP++a++g ++ l +++s +
CU928162_2 235 RLSQFADDLAHELRTPINALLGQNQVTLS---------QTRSIAE-- 270

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
y++ + ++e+e ++rL +++L l+r++ +
CU928162_2 271 ---------YQKTIAGNIEELENISRLTENILFLARADKN 301

CU928162_4700: domain 1 of 1, from 142 to 202: score 45.0, E = 2.6e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ f+a+++HELRTPL+++r+++elL + t+
CU928162_4 142 NERLFTADVAHELRTPLAGVRLHLELLAK---------TH------- 172

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + + ++++ + +++lL+l+r+++
CU928162_4 173 ----------HIDVAPLVARLDQMMESVSQLLQLARAGQS 202

CU928162_1768: domain 1 of 1, from 211 to 271: score 42.4, E = 1.5e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+k +++ +++HELRTPL +r +e+ + ls+ +
CU928162_1 211 SKKQLIDGIAHELRTPLVRLRYRLEMSDN-----------LSAAE-- 244

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + r++ +l++Li++lL+++r++ +
CU928162_1 245 -------------SQALNRDISQLEALIEELLTYARLDRP 271


Histogram of all scores:
score obs exp (one = represents 16 sequences)
----- --- ---
-16 1 0|=
-15 2 0|=
-14 25 0|==
-13 72 3|*====
-12 252 112|======*=========
-11 547 582|=================================== *
-10 858 1080|====================================================== *
-9 920 1116|==========================================================*
-8 798 835|================================================== *
-7 583 526|================================*====
-6 340 303|==================*===
-5 230 166|==========*====
-4 100 88|=====*=
-3 66 46|==*==
-2 32 24|=*
-1 28 12|*=
0 20 6|*=
1 8 3|*
2 7 1|*
3 3 0|=
4 0 0|
> 5 23 -|==


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 348.0132
P(chi-square) = 0

Total sequences searched: 5123

Whole sequence top hits:
tophits_s report:
Total hits: 20
Satisfying E cutoff: 20
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 20
Satisfying E cutoff: 20
Total memory: 28K


Acknowledgements:

This research is funded by:

Developed by: