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Thermotogae
Classification of phyla is from NCBI page
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264 projects found  

3 accessions found for Escherichia coli O127:H6 str. E2348/69  

Data for FM180568  

Available Atlases
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hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: FM180568.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
FM180568_3053 CDS_3147009-3149765 100.1 5.7e-28 1
FM180568_0335 CDS_376932-378227 91.0 2.3e-25 1
FM180568_2563 CDS_2640787-2644380 81.6 1e-22 1
FM180568_0978 CDS_1043422-1040690 80.7 1.8e-22 1
FM180568_2363 CDS_2447045-2444244 80.6 2e-22 1
FM180568_3489 CDS_3631163-3628827 78.9 6e-22 1
FM180568_2364 CDS_2447260-2449086 77.9 1.1e-21 1
FM180568_2833 CDS_2920743-2919316 75.4 5.9e-21 1
FM180568_2221 CDS_2285335-2286738 69.8 2.3e-19 1
FM180568_4216 CDS_4420101-4418728 66.6 1.8e-18 1
FM180568_4699 CDS_4960599-4962023 62.4 2.7e-17 1
FM180568_4310 CDS_4531281-4532657 60.1 1.2e-16 1
FM180568_4175 CDS_4372457-4371408 59.7 1.7e-16 1
FM180568_0584 CDS_653150-650466 59.6 1.7e-16 1
FM180568_0470 CDS_527228-525786 59.0 2.6e-16 1
FM180568_3316 CDS_3451251-3452600 56.9 9.9e-16 1
FM180568_3649 CDS_3785308-3783956 55.0 3.5e-15 1
FM180568_2079 CDS_2134462-2133104 52.3 2e-14 1
FM180568_4440 CDS_4683056-4681965 45.0 2.4e-12 1
FM180568_1694 CDS_1758156-1759457 42.4 1.3e-11 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
FM180568_3053 1/1 292 357 .. 1 87 [] 100.1 5.7e-28
FM180568_0335 1/1 203 269 .. 1 87 [] 91.0 2.3e-25
FM180568_2563 1/1 711 777 .. 1 87 [] 81.6 1e-22
FM180568_0978 1/1 443 508 .. 1 87 [] 80.7 1.8e-22
FM180568_2363 1/1 453 518 .. 1 87 [] 80.6 2e-22
FM180568_3489 1/1 282 347 .. 1 87 [] 78.9 6e-22
FM180568_2364 1/1 388 453 .. 1 87 [] 77.9 1.1e-21
FM180568_2833 1/1 249 317 .. 1 87 [] 75.4 5.9e-21
FM180568_2221 1/1 240 304 .. 1 87 [] 69.8 2.3e-19
FM180568_4216 1/1 238 300 .. 1 87 [] 66.6 1.8e-18
FM180568_4699 1/1 255 320 .. 1 87 [] 62.4 2.7e-17
FM180568_4310 1/1 237 303 .. 1 87 [] 60.1 1.2e-16
FM180568_4175 1/1 129 186 .. 1 79 [. 59.7 1.7e-16
FM180568_0584 1/1 663 730 .. 1 87 [] 59.6 1.7e-16
FM180568_0470 1/1 261 327 .. 1 87 [] 59.0 2.6e-16
FM180568_3316 1/1 236 302 .. 1 87 [] 56.9 9.9e-16
FM180568_3649 1/1 233 293 .. 1 87 [] 55.0 3.5e-15
FM180568_2079 1/1 235 301 .. 1 87 [] 52.3 2e-14
FM180568_4440 1/1 142 202 .. 1 87 [] 45.0 2.4e-12
FM180568_1694 1/1 211 271 .. 1 87 [] 42.4 1.3e-11

Alignments of top-scoring domains:
FM180568_3053: domain 1 of 1, from 292 to 357: score 100.1, E = 5.7e-28
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
kseflan+sHELRTPL++++g++ l l+ tel++ q
FM180568_3 292 IKSEFLANMSHELRTPLNGVIGFTRLTLK---------TELTPTQ-- 327

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+ l+ti+r+a+ ll++ind+Ld+s++eag
FM180568_3 328 ----------RDHLNTIERSANNLLAIINDVLDFSKLEAG 357

FM180568_0335: domain 1 of 1, from 203 to 269: score 91.0, E = 2.3e-25
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++ f+an+sHELRTPLt+++gy+e++ e ++l r
FM180568_0 203 ARRNFFANVSHELRTPLTVLQGYLEMMDE---------QPLEGAVR- 239

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l+t++++++r++ L+ +lL+ls+iea
FM180568_0 240 ----------EKALHTMREQTQRMEGLVKQLLTLSKIEAA 269

FM180568_2563: domain 1 of 1, from 711 to 777: score 81.6, E = 1e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks+fla++sHE+RTP+++I+g++elL + ls eqr
FM180568_2 711 AKSQFLATMSHEIRTPISSIMGFLELLSG---------SGLSKEQR- 747

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e+++ ++ +++ll Li ++Ld +ie+g
FM180568_2 748 ----------VEAISLAYATGQSLLGLIGEILDVDKIESG 777

FM180568_0978: domain 1 of 1, from 443 to 508: score 80.7, E = 1.8e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks fla++sHE+RTPL +I+g+a+lL + ++ q
FM180568_0 443 AKSAFLAAMSHEIRTPLYGILGTAQLLAD---------NPALNAQ-- 478

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+ l+ i +++e+ll ++nd+Ld+s ieag
FM180568_0 479 ----------RDDLRAITDSGESLLTILNDILDYSAIEAG 508

FM180568_2363: domain 1 of 1, from 453 to 518: score 80.6, E = 2e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ks fla++sHELRTPL +I+g+++lL++ el+
FM180568_2 453 SKSMFLATVSHELRTPLYGIIGNLDLLQT---------KELPKGV-- 488

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ + +++ ll++i+d+Ld+s+ie++
FM180568_2 489 ----------DRLVTAMNNSSSLLLKIISDILDFSKIESE 518

FM180568_3489: domain 1 of 1, from 282 to 347: score 78.9, E = 6e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k+ f++++sHELRTPL++I g++ +Ll+ tel++eq
FM180568_3 282 DKTTFISTISHELRTPLNGIVGLSRILLD---------TELTAEQ-- 317

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++yl+ti+ +a l ++ nd+ d+ ++e
FM180568_3 318 ----------EKYLKTIHVSAVTLGNIFNDIIDMDKMERR 347

FM180568_2364: domain 1 of 1, from 388 to 453: score 77.9, E = 1.1e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++e++a+++HE R+PLtaIrgy+++L+ +++++ +
FM180568_2 388 TLGELMAGVAHEVRNPLTAIRGYVQILRQ---------QTRDPIH-- 423

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+eyl+++l+e++++++ i++lL++sr ++
FM180568_2 424 ----------QEYLSVVLKEIDSINKVIQQLLEFSRPRHS 453

FM180568_2833: domain 1 of 1, from 249 to 317: score 75.4, E = 5.9e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +fl++lsHEL+TPL+++r +elL +++ ++l++eq
FM180568_2 249 QRHQFLRHLSHELKTPLASMREGTELLADQV------VGPLTPEQ-- 287

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e +++++++++ l++Li++lLd+ r +a
FM180568_2 288 ----------KEVVSILDSSSRNLQKLIEQLLDYNRKQAD 317

FM180568_2221: domain 1 of 1, from 240 to 304: score 69.8, E = 2.3e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+a++sHELRTPL+++rg +e++++++ + ++e+
FM180568_2 240 MRRDFMADISHELRTPLAVLRGELEAIQDGV-------RKFTPET-- 277

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +++ e+ l +L++dl +ls ++g
FM180568_2 278 -------------VASLQAEVGTLTKLVDDLHQLSMSDEG 304

FM180568_4216: domain 1 of 1, from 238 to 300: score 66.6, E = 1.8e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++++l+++sHELRTPLt +++ + lL++ +++
FM180568_4 238 SQQRLLSDISHELRTPLTRLQLGTALLRR---------RSGESKE-- 273

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
le+i+ ea+rl+++indlL +sr ++
FM180568_4 274 -------------LERIETEAQRLDSMINDLLVMSRNQQK 300

FM180568_4699: domain 1 of 1, from 255 to 320: score 62.4, E = 2.7e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ + +l HEL+ PL+aIrg+ae+L+e ++ +e
FM180568_4 255 YIEQYVYALTHELKSPLAAIRGAAEILRE---------GPPPEVV-- 290

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++++ il + r+++L++ lL +r+e+
FM180568_4 291 ----------ARFTDNILTQNARMQALVETLLRQARLENR 320

FM180568_4310: domain 1 of 1, from 237 to 303: score 60.1, E = 1.2e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++ ++a+++HE+R+PL++I+g+a+ e ++ ++ e
FM180568_4 237 ALGHLAAGVAHEIRNPLSSIKGLAKYFAE--------RASAGGEA-- 273

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ +++ +ea+rl+r +++lL+l + +
FM180568_4 274 ----------HQLAQVMAKEADRLNRVVSELLELVKPTHL 303

FM180568_4175: domain 1 of 1, from 129 to 186: score 59.7, E = 1.7e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a ++++++l+HE+++PL ++rg+a+lL + +l+++ +
FM180568_4 129 AARDLVRGLAHEIKNPLGGLRGAAQLLSK----------ALPDPSL- 164

peLRledpeyreyletilreaerllrLindlL<-*
ey+++i+++a+rl++L+++lL
FM180568_4 165 ----------LEYTKVIIEQADRLRNLVDRLL 186

FM180568_0584: domain 1 of 1, from 663 to 730: score 59.6, E = 1.7e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +la+lsH+LRTPLt++ g ae+L +l + ++++
FM180568_0 663 IRNALLAALSHDLRTPLTVLFGQAEILTLDL-------ASEGSPH-- 700

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ + i++ + rL+n+lLd++ri++g
FM180568_0 701 ----------ARQASEIRQHVLNTTRLVNNLLDMARIQSG 730

FM180568_0470: domain 1 of 1, from 261 to 327: score 59.0, E = 2.6e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++s f a+++HE+RTP+t +++ +e++l + +s +++
FM180568_0 261 RQSNFSADIAHEIRTPITNLITQTEIALS---------QSRSQKEL- 297

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ + l+e+ r+ ++++d+L l++++++
FM180568_0 298 ----------EDVHYSNLEELTRMAKMVSDMLFLAQADNN 327

FM180568_3316: domain 1 of 1, from 236 to 302: score 56.9, E = 9.9e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++f+++++HELR PLta++ +e+++ ++ + + r
FM180568_3 236 RERRFTSDAAHELRSPLTALKVQTEVAQL---------SDDDQQAR- 272

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l +++ ++r rL+++lL+lsr+++
FM180568_3 273 ----------KKALLQLHSGIDRATRLVDQLLTLSRLDSL 302

FM180568_3649: domain 1 of 1, from 233 to 293: score 55.0, E = 3.5e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ ++a++sH+LRTPLt Ir+++e++ e ++
FM180568_3 233 DRTLLMAGVSHDLRTPLTRIRLATEMMSE---------QD------- 263

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ e+i +++e ++++i+++ d+ r +++
FM180568_3 264 ----------GYLAESINKDIEECNAIIEQFIDYLRTGQE 293

FM180568_2079: domain 1 of 1, from 235 to 301: score 52.3, E = 2e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++s+f+ +l+HELRTP++a++g ++ l +++s +
FM180568_2 235 RLSQFADDLAHELRTPINALLGQNQVTLS---------QTRSIAE-- 270

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
y++ + ++e+e ++rL +++L l+r++ +
FM180568_2 271 ---------YQKTIAGNIEELENISRLTENILFLARADKN 301

FM180568_4440: domain 1 of 1, from 142 to 202: score 45.0, E = 2.4e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ f+a+++HELRTPL+++r+++elL + t+
FM180568_4 142 NERLFTADVAHELRTPLAGVRLHLELLAK---------TH------- 172

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + + ++++ + +++lL+l+r+++
FM180568_4 173 ----------HIDVAPLVARLDQMMESVSQLLQLARAGQS 202

FM180568_1694: domain 1 of 1, from 211 to 271: score 42.4, E = 1.3e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+k +++ +++HELRTPL +r +e+ + ls+ +
FM180568_1 211 SKKQLIDGIAHELRTPLVRLRYRLEMSDN-----------LSAAE-- 244

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + r++ +l++Li++lL+++r++ +
FM180568_1 245 -------------SQALNRDISQLEALIEELLTYARLDRP 271


Histogram of all scores:
score obs exp (one = represents 15 sequences)
----- --- ---
-16 1 0|=
-15 4 0|=
-14 15 0|=
-13 64 3|*====
-12 201 104|======*=======
-11 463 539|=============================== *
-10 782 1001|===================================================== *
-9 874 1034|==========================================================*
-8 748 774|================================================== *
-7 559 488|================================*=====
-6 338 280|==================*====
-5 202 154|==========*===
-4 100 82|=====*=
-3 82 43|==*===
-2 34 22|=*=
-1 34 11|*==
0 16 6|*=
1 5 3|*
2 7 1|*
3 2 0|=
4 0 0|
> 5 23 -|==


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 311.0360
P(chi-square) = 0

Total sequences searched: 4703

Whole sequence top hits:
tophits_s report:
Total hits: 20
Satisfying E cutoff: 20
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 20
Satisfying E cutoff: 20
Total memory: 28K


Acknowledgements:

This research is funded by:

Developed by: