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Thermotogae
Classification of phyla is from NCBI page
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264 projects found  

1 accessions found for Salmonella enterica subsp. enterica serovar Paratyphi A str. AKU_12601  

Data for FM200053  

Available Atlases
Other Plots
hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: FM200053.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
FM200053_2765 CDS_2921179-2923935 100.2 5.1e-28 1
FM200053_2271 CDS_2417029-2415734 88.2 1.2e-24 1
FM200053_1427 CDS_1527880-1530642 82.3 5.8e-23 1
FM200053_0579 CDS_671709-674555 80.6 1.8e-22 1
FM200053_3125 CDS_3295966-3293630 78.9 5.3e-22 1
FM200053_3598 CDS_3810194-3812929 72.8 2.8e-20 1
FM200053_0294 CDS_339230-340525 69.6 2.3e-19 1
FM200053_3804 CDS_4043469-4042096 67.0 1.2e-18 1
FM200053_0719 CDS_815600-814197 63.5 1.3e-17 1
FM200053_3901 CDS_4156429-4157826 62.5 2.3e-17 1
FM200053_1991 CDS_2116029-2118713 61.1 6.1e-17 1
FM200053_3750 CDS_3989073-3988024 60.3 1e-16 1
FM200053_4274 CDS_4569490-4570716 59.8 1.3e-16 1
FM200053_1714 CDS_1809863-1811227 57.5 6.3e-16 1
FM200053_2983 CDS_3147708-3149057 55.9 1.8e-15 1
FM200053_3289 CDS_3460882-3459647 54.9 3.4e-15 1
FM200053_3993 CDS_4281329-4280259 47.7 3.8e-13 1
FM200053_1350 CDS_1459766-1461070 47.4 4.5e-13 1
FM200053_2588 CDS_2745137-2743722 36.6 5.2e-10 1
FM200053_1433 CDS_1536035-1534350 31.5 1.4e-08 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
FM200053_2765 1/1 292 357 .. 1 87 [] 100.2 5.1e-28
FM200053_2271 1/1 203 269 .. 1 87 [] 88.2 1.2e-24
FM200053_1427 1/1 395 460 .. 1 87 [] 82.3 5.8e-23
FM200053_0579 1/1 469 534 .. 1 87 [] 80.6 1.8e-22
FM200053_3125 1/1 282 347 .. 1 87 [] 78.9 5.3e-22
FM200053_3598 1/1 444 509 .. 1 87 [] 72.8 2.8e-20
FM200053_0294 1/1 204 272 .. 1 87 [] 69.6 2.3e-19
FM200053_3804 1/1 238 300 .. 1 87 [] 67.0 1.2e-18
FM200053_0719 1/1 240 304 .. 1 87 [] 63.5 1.3e-17
FM200053_3901 1/1 246 312 .. 1 87 [] 62.5 2.3e-17
FM200053_1991 1/1 663 730 .. 1 87 [] 61.1 6.1e-17
FM200053_3750 1/1 129 186 .. 1 79 [. 60.3 1e-16
FM200053_4274 1/1 189 254 .. 1 87 [] 59.8 1.3e-16
FM200053_1714 1/1 236 302 .. 1 87 [] 57.5 6.3e-16
FM200053_2983 1/1 236 302 .. 1 87 [] 55.9 1.8e-15
FM200053_3289 1/1 194 254 .. 1 87 [] 54.9 3.4e-15
FM200053_3993 1/1 142 202 .. 1 87 [] 47.7 3.8e-13
FM200053_1350 1/1 212 272 .. 1 87 [] 47.4 4.5e-13
FM200053_2588 1/1 246 311 .. 1 87 [] 36.6 5.2e-10
FM200053_1433 1/1 326 395 .. 1 87 [] 31.5 1.4e-08

Alignments of top-scoring domains:
FM200053_2765: domain 1 of 1, from 292 to 357: score 100.2, E = 5.1e-28
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
kseflan+sHELRTPL++++g++ l l+ tel++ q
FM200053_2 292 IKSEFLANMSHELRTPLNGVIGFTRLTLK---------TELNPTQ-- 327

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+ l+ti+r+a+ ll++ind+Ld+s++eag
FM200053_2 328 ----------RDHLNTIERSANNLLAIINDVLDFSKLEAG 357

FM200053_2271: domain 1 of 1, from 203 to 269: score 88.2, E = 1.2e-24
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++ f+an+sHELRTPLt+++gy+e+++e ++l r
FM200053_2 203 ARRNFFANVSHELRTPLTVLQGYLEMMQE---------QALEGAMR- 239

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l+t+++++ r++ L+ +lL+ls+iea
FM200053_2 240 ----------EKALHTMREQTYRMEGLVKQLLTLSKIEAA 269

FM200053_1427: domain 1 of 1, from 395 to 460: score 82.3, E = 5.8e-23
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ks l +sHELRTP+++++g++elL++ t+l+ eq
FM200053_1 395 RKSIHLTVISHELRTPMNGVLGAIELLQT---------TPLNIEQ-- 430

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + +t+++++ +ll++in+lLd+srie+g
FM200053_1 431 ----------QGLADTARNCTLSLLAIINNLLDFSRIESG 460

FM200053_0579: domain 1 of 1, from 469 to 534: score 80.6, E = 1.8e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ks fla++sHELRTPL +I+g+++lL++ el+
FM200053_0 469 SKSMFLATVSHELRTPLYGIIGNLDLLQT---------KELPKGV-- 504

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ + +++ ll++i+d+Ld+s+ie++
FM200053_0 505 ----------DRLVTAMNNSSSLLLKIISDILDFSKIESE 534

FM200053_3125: domain 1 of 1, from 282 to 347: score 78.9, E = 5.3e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k+ f++++sHELRTPL++I g++ +Ll+ t+l++eq
FM200053_3 282 DKTTFISTISHELRTPLNGIVGLSRILLD---------TDLTAEQ-- 317

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++yl+ti+ +a l ++ nd+ d+ ++e
FM200053_3 318 ----------EKYLKTIHVSAVTLGNIFNDIIDMDKMERR 347

FM200053_3598: domain 1 of 1, from 444 to 509: score 72.8, E = 2.8e-20
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks fla++sHE+RTPL +I+g+++lL + +l +
FM200053_3 444 AKSTFLAAMSHEIRTPLYGILGTVQLLAD---------KPLMANY-- 479

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+ l+ i +++e+ll+++nd+Ld+s ie g
FM200053_3 480 ----------RDDLQAINDSGESLLAILNDILDYSAIEVG 509

FM200053_0294: domain 1 of 1, from 204 to 272: score 69.6, E = 2.3e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +fl++lsHEL+TPL+++r +elL +++ ++l++eq
FM200053_0 204 QRHQFLRHLSHELKTPLASMREGTELLADQV------VGPLTPEQ-- 242

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e +++++++++ l++Li++lLd+ r
FM200053_0 243 ----------KEVVDILDDSSRNLQKLIEQLLDYNRKLVD 272

FM200053_3804: domain 1 of 1, from 238 to 300: score 67.0, E = 1.2e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++++l+++sHELRTPLt +++ + lL++ +++
FM200053_3 238 SQQRLLSDISHELRTPLTRLQLGTALLRR---------RGGESKE-- 273

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
le+i+ ea+rl+++indlL +sr ++
FM200053_3 274 -------------LERIETEAQRLDSMINDLLVMSRNQQK 300

FM200053_0719: domain 1 of 1, from 240 to 304: score 63.5, E = 1.3e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+a++sHELRTPL+++rg +e++++++ ++e
FM200053_0 240 MRRDFMADISHELRTPLAVLRGELEAIQDGV-------RQFTPES-- 277

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +++ e+ l +L++dl +ls ++g
FM200053_0 278 -------------VTSLQAEVGTLTKLVDDLHQLSLSDEG 304

FM200053_3901: domain 1 of 1, from 246 to 312: score 62.5, E = 2.3e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++ ++a+++HE+R+PL++I+g+a+ e +t+++ e
FM200053_3 246 AMGHLAAGVAHEIRNPLSSIKGLAKYFAE--------RTPAGGES-- 282

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e+ +++ +ea+rl+r +++lL+l + +
FM200053_3 283 ----------HELAQVMAKEADRLNRVVSELLELVKPAHL 312

FM200053_1991: domain 1 of 1, from 663 to 730: score 61.1, E = 6.1e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +la+lsH+LRTPLt++ g ae+L +l + +++++
FM200053_1 663 IRNALLAALSHDLRTPLTVLFGQAEILTLDL-------ASAGSPH-- 700

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ + i++ + rL+n+lLd++ri++g
FM200053_1 701 ----------ARQASEIRQHILNTTRLVNNLLDMARIQSG 730

FM200053_3750: domain 1 of 1, from 129 to 186: score 60.3, E = 1e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a ++++++l+HE+++PL ++rg+a+lL + +l+++ +
FM200053_3 129 AARDLVRGLAHEIKNPLGGLRGAAQLLSK----------ALPDPAL- 164

peLRledpeyreyletilreaerllrLindlL<-*
ey+++i+++a+rl++L+++lL
FM200053_3 165 ----------TEYTKVIIEQADRLRNLVDRLL 186

FM200053_4274: domain 1 of 1, from 189 to 254: score 59.8, E = 1.3e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++ + +l HEL+ PL+aIrg+ae+L+e ++ +
FM200053_4 189 EIEQYVYALTHELKSPLAAIRGAAEILRE---------GPPADVV-- 224

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++e il + r+++L++ lL +r+e+
FM200053_4 225 ----------TRFTENILAQNTRMQALVETLLRQARLENR 254

FM200053_1714: domain 1 of 1, from 236 to 302: score 57.5, E = 6.3e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+ +l+HELRTP++ ++g +++l +e+s+e+
FM200053_1 236 RLNQFADDLAHELRTPVNILLGKNQVMLS---------QERSAEE-- 271

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
y+++l ++e+e l+rL +++L l+r+e++
FM200053_1 272 ---------YQQALVDNIEELEGLSRLTENILFLARAEHQ 302

FM200053_2983: domain 1 of 1, from 236 to 302: score 55.9, E = 1.8e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++f+++++HELR PL+a++ +e+++ + ++ r
FM200053_2 236 RERRFTSDAAHELRSPLAALKVQTEVAQL---------SGDDPLSR- 272

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++l ++ ++r rL+++lL+lsr+++
FM200053_2 273 ----------DKALTQLHAGIDRATRLVDQLLTLSRLDSL 302

FM200053_3289: domain 1 of 1, from 194 to 254: score 54.9, E = 3.4e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ ++a++sH+LRTPLt Ir+++e++ e e+
FM200053_3 194 DRTLLMAGVSHDLRTPLTRIRLATEMMGE--------------ED-- 224

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ e+i +++e ++++i+++ d+ r +++
FM200053_3 225 ----------GYLAESINKDIEECNAIIEQFIDYLRTGQE 254

FM200053_3993: domain 1 of 1, from 142 to 202: score 47.7, E = 3.8e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ f+a+++HELRTPL+++r+++elL + t+
FM200053_3 142 NERLFTADVAHELRTPLSGVRLHLELLSK---------TH------- 172

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ ++ ++++ + +++lL+l+r ++
FM200053_3 173 ----------NVDVAPLIARLDQMMDSVSQLLQLARVGQS 202

FM200053_1350: domain 1 of 1, from 212 to 272: score 47.4, E = 4.5e-13
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+k +++ +++HELRTPL +r +e+ ++ l++++
FM200053_1 212 SKKQLIDGIAHELRTPLVRLRYRLEMSEN-----------LTPPE-- 245

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + r++ +l++Li++lL+++r++ +
FM200053_1 246 -------------SQALNRDIGQLEALIEELLTYARLDRP 272

FM200053_2588: domain 1 of 1, from 246 to 311: score 36.6, E = 5.2e-10
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f a++sH+L+TPL+++++ a ++l+ + + +
FM200053_2 246 RQERFSADASHQLKTPLAVLKTQAAVALA----------SQHPHH-- 280

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ e l+ + +++ +L ++lL+ls +
FM200053_2 281 ---------WYESLQAMSVTLDSTIQLTERLLQLSAVKHK 311

FM200053_1433: domain 1 of 1, from 326 to 395: score 31.5, E = 1.4e-08
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++e++++ +HEL++PL+aIr ya+ +l +l +++e++ l
FM200053_1 326 VLGEMTSGFAHELNQPLSAIRHYAQGCLIRL-------RAADEQHPL 365

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+le i+++a+r + +++l+ +g
FM200053_1 366 ----------LPALEQIDQQAQRGADTLRNLRHWVSQAQG 395


Histogram of all scores:
score obs exp (one = represents 13 sequences)
----- --- ---
-15 2 0|=
-14 26 0|==
-13 60 3|*====
-12 212 93|=======*=========
-11 449 483|=================================== *
-10 681 896|===================================================== *
-9 761 926|==========================================================*
-8 684 693|=====================================================*
-7 490 436|=================================*====
-6 283 251|===================*==
-5 203 137|==========*=====
-4 93 73|=====*==
-3 36 38|==*
-2 27 20|=*=
-1 23 10|*=
0 14 5|*=
1 5 2|*
2 5 1|*
3 2 0|=
4 0 0|
> 5 22 -|==


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 310.5337
P(chi-square) = 0

Total sequences searched: 4284

Whole sequence top hits:
tophits_s report:
Total hits: 20
Satisfying E cutoff: 20
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 20
Satisfying E cutoff: 20
Total memory: 28K


Acknowledgements:

This research is funded by:

Developed by: