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Chlamydiae/Verrucomicrobia Chloroflexi Cyanobacteria
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Firmicutes Fusobacteria Gammaproteobacteria
Other Bacteria Planctomycetes Spirochaetes
Thermotogae
Classification of phyla is from NCBI page
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264 projects found  

2 accessions found for Escherichia coli 042  

Data for FN554766  

Available Atlases
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hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: FN554766.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
FN554766_2977 CDS_3177000-3179756 100.1 5.9e-28 1
FN554766_0431 CDS_477744-479039 91.0 2.4e-25 1
FN554766_1057 CDS_1154580-1151866 80.7 1.8e-22 1
FN554766_2458 CDS_2591747-2588898 80.6 2.1e-22 1
FN554766_3492 CDS_3721861-3719525 77.6 1.4e-21 1
FN554766_2759 CDS_2945588-2944161 75.4 6.1e-21 1
FN554766_2459 CDS_2591914-2593740 73.6 2e-20 1
FN554766_2317 CDS_2425887-2427290 69.8 2.4e-19 1
FN554766_4277 CDS_4577235-4575862 66.6 1.9e-18 1
FN554766_4883 CDS_5237023-5238447 62.4 2.9e-17 1
FN554766_4360 CDS_4676350-4677717 61.5 5.3e-17 1
FN554766_0595 CDS_673013-671565 61.0 7.3e-17 1
FN554766_3306 CDS_3532441-3533790 60.7 9.1e-17 1
FN554766_4235 CDS_4528497-4527448 59.7 1.7e-16 1
FN554766_0708 CDS_796088-793401 59.6 1.8e-16 1
FN554766_3656 CDS_3882037-3880685 55.0 3.6e-15 1
FN554766_2115 CDS_2210368-2209010 52.3 2.1e-14 1
FN554766_4466 CDS_4804012-4802921 45.0 2.5e-12 1
FN554766_1770 CDS_1852387-1853688 42.4 1.4e-11 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
FN554766_2977 1/1 292 357 .. 1 87 [] 100.1 5.9e-28
FN554766_0431 1/1 203 269 .. 1 87 [] 91.0 2.4e-25
FN554766_1057 1/1 433 498 .. 1 87 [] 80.7 1.8e-22
FN554766_2458 1/1 469 534 .. 1 87 [] 80.6 2.1e-22
FN554766_3492 1/1 282 347 .. 1 87 [] 77.6 1.4e-21
FN554766_2759 1/1 249 317 .. 1 87 [] 75.4 6.1e-21
FN554766_2459 1/1 388 453 .. 1 87 [] 73.6 2e-20
FN554766_2317 1/1 240 304 .. 1 87 [] 69.8 2.4e-19
FN554766_4277 1/1 238 300 .. 1 87 [] 66.6 1.9e-18
FN554766_4883 1/1 255 320 .. 1 87 [] 62.4 2.9e-17
FN554766_4360 1/1 234 300 .. 1 87 [] 61.5 5.3e-17
FN554766_0595 1/1 261 327 .. 1 87 [] 61.0 7.3e-17
FN554766_3306 1/1 236 302 .. 1 87 [] 60.7 9.1e-17
FN554766_4235 1/1 129 186 .. 1 79 [. 59.7 1.7e-16
FN554766_0708 1/1 664 731 .. 1 87 [] 59.6 1.8e-16
FN554766_3656 1/1 233 293 .. 1 87 [] 55.0 3.6e-15
FN554766_2115 1/1 235 301 .. 1 87 [] 52.3 2.1e-14
FN554766_4466 1/1 142 202 .. 1 87 [] 45.0 2.5e-12
FN554766_1770 1/1 211 271 .. 1 87 [] 42.4 1.4e-11

Alignments of top-scoring domains:
FN554766_2977: domain 1 of 1, from 292 to 357: score 100.1, E = 5.9e-28
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
kseflan+sHELRTPL++++g++ l l+ tel++ q
FN554766_2 292 IKSEFLANMSHELRTPLNGVIGFTRLTLK---------TELTPTQ-- 327

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+ l+ti+r+a+ ll++ind+Ld+s++eag
FN554766_2 328 ----------RDHLNTIERSANNLLAIINDVLDFSKLEAG 357

FN554766_0431: domain 1 of 1, from 203 to 269: score 91.0, E = 2.4e-25
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++ f+an+sHELRTPLt+++gy+e++ e ++l r
FN554766_0 203 ARRNFFANVSHELRTPLTVLQGYLEMMDE---------QPLEGAVR- 239

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l+t++++++r++ L+ +lL+ls+iea
FN554766_0 240 ----------EKALHTMREQTQRMEGLVKQLLTLSKIEAA 269

FN554766_1057: domain 1 of 1, from 433 to 498: score 80.7, E = 1.8e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks fla++sHE+RTPL +I+g+a+lL + ++ q
FN554766_1 433 AKSAFLAAMSHEIRTPLYGILGTAQLLAD---------NPALNAQ-- 468

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+ l+ i +++e+ll ++nd+Ld+s ieag
FN554766_1 469 ----------RDDLRAITDSGESLLTILNDILDYSAIEAG 498

FN554766_2458: domain 1 of 1, from 469 to 534: score 80.6, E = 2.1e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ks fla++sHELRTPL +I+g+++lL++ el+
FN554766_2 469 SKSMFLATVSHELRTPLYGIIGNLDLLQT---------KELPKGV-- 504

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ + +++ ll++i+d+Ld+s+ie++
FN554766_2 505 ----------DRLVTAMNNSSSLLLKIISDILDFSKIESE 534

FN554766_3492: domain 1 of 1, from 282 to 347: score 77.6, E = 1.4e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k+ f++++sHELRTPL++I g++ +Ll+ tel+ eq
FN554766_3 282 DKTTFISTISHELRTPLNGIVGLSRILLD---------TELTVEQ-- 317

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++yl+ti+ +a l ++ nd+ d+ ++e
FN554766_3 318 ----------EKYLKTIHVSAVTLGNIFNDIIDMDKMERR 347

FN554766_2759: domain 1 of 1, from 249 to 317: score 75.4, E = 6.1e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +fl++lsHEL+TPL+++r +elL +++ ++l++eq
FN554766_2 249 QRHQFLRHLSHELKTPLASMREGTELLADQV------VGPLTPEQ-- 287

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e +++++++++ l++Li++lLd+ r +a
FN554766_2 288 ----------KEVVSILDSSSRNLQKLIEQLLDYNRKQAD 317

FN554766_2459: domain 1 of 1, from 388 to 453: score 73.6, E = 2e-20
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++e++a+++HE R+PLtaIrgy+++L+ ++ + +
FN554766_2 388 TLGELMAGVAHEVRNPLTAIRGYVQILRQ---------QTSDLIH-- 423

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+eyl+++l+e++++++ i++lL++sr ++
FN554766_2 424 ----------QEYLSVVLKEIDSINKVIQQLLEFSRPRHS 453

FN554766_2317: domain 1 of 1, from 240 to 304: score 69.8, E = 2.4e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+a++sHELRTPL+++rg +e++++++ + ++e+
FN554766_2 240 MRRDFMADISHELRTPLAVLRGELEAIQDGV-------RKFTPET-- 277

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +++ e+ l +L++dl +ls ++g
FN554766_2 278 -------------VASLQAEVGTLTKLVDDLHQLSMSDEG 304

FN554766_4277: domain 1 of 1, from 238 to 300: score 66.6, E = 1.9e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++++l+++sHELRTPLt +++ + lL++ +++
FN554766_4 238 SQQRLLSDISHELRTPLTRLQLGTALLRR---------RSGESKE-- 273

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
le+i+ ea+rl+++indlL +sr ++
FN554766_4 274 -------------LERIETEAQRLDSMINDLLVMSRNQQK 300

FN554766_4883: domain 1 of 1, from 255 to 320: score 62.4, E = 2.9e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ + +l HEL+ PL+aIrg+ae+L+e ++ +e
FN554766_4 255 YIEQYVYALTHELKSPLAAIRGAAEILRE---------GPPPEVV-- 290

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++++ il + r+++L++ lL +r+e+
FN554766_4 291 ----------ARFTDNILTQNARMQALVETLLRQARLENR 320

FN554766_4360: domain 1 of 1, from 234 to 300: score 61.5, E = 5.3e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++ ++a+++HE+R+PL++I+g+a+ e +++++ e
FN554766_4 234 ALGHLAAGVAHEIRNPLSSIKGLAKYFAE--------RAPAGGEA-- 270

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ +++ +ea+rl+r +++lL+l + +
FN554766_4 271 ----------HQLAQVMAKEADRLNRVVSELLELVKPTHL 300

FN554766_0595: domain 1 of 1, from 261 to 327: score 61.0, E = 7.3e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++s f a+++HE+RTP+t +++ +e++l + +s +++
FN554766_0 261 RQSNFSADIAHEIRTPITNLITQTEIALS---------QSRSQKEL- 297

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ l + l+e+ r+ ++++d+L l++++++
FN554766_0 298 ----------EDVLYSNLEELTRMAKMVSDMLFLAQADNN 327

FN554766_3306: domain 1 of 1, from 236 to 302: score 60.7, E = 9.1e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++f+++++HELR PLta++ +e+++ ++ +++ r
FN554766_3 236 RERRFTSDAAHELRSPLTALKVQTEVAQL---------SDDDPQAR- 272

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l +++ ++r rL+++lL+lsr+++
FN554766_3 273 ----------KKALLQLHSGIDRATRLVDQLLTLSRLDSL 302

FN554766_4235: domain 1 of 1, from 129 to 186: score 59.7, E = 1.7e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a ++++++l+HE+++PL ++rg+a+lL + +l+++ +
FN554766_4 129 AARDLVRGLAHEIKNPLGGLRGAAQLLSK----------ALPDPSL- 164

peLRledpeyreyletilreaerllrLindlL<-*
ey+++i+++a+rl++L+++lL
FN554766_4 165 ----------LEYTKVIIEQADRLRNLVDRLL 186

FN554766_0708: domain 1 of 1, from 664 to 731: score 59.6, E = 1.8e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +la+lsH+LRTPLt++ g ae+L +l + ++++
FN554766_0 664 IRNALLAALSHDLRTPLTVLFGQAEILTLDL-------ASEGSPH-- 701

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ + i++ + rL+n+lLd++ri++g
FN554766_0 702 ----------ARQASEIRQHVLNTTRLVNNLLDMARIQSG 731

FN554766_3656: domain 1 of 1, from 233 to 293: score 55.0, E = 3.6e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ ++a++sH+LRTPLt Ir+++e++ e ++
FN554766_3 233 DRTLLMAGVSHDLRTPLTRIRLATEMMSE---------QD------- 263

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ e+i +++e ++++i+++ d+ r +++
FN554766_3 264 ----------GYLAESINKDIEECNAIIEQFIDYLRTGQE 293

FN554766_2115: domain 1 of 1, from 235 to 301: score 52.3, E = 2.1e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++s+f+ +l+HELRTP++a++g ++ l +++s +
FN554766_2 235 RLSQFADDLAHELRTPINALLGQNQVTLS---------QTRSIAE-- 270

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
y++ + ++e+e ++rL +++L l+r++ +
FN554766_2 271 ---------YQKTIAGNIEELENISRLTENILFLARADKN 301

FN554766_4466: domain 1 of 1, from 142 to 202: score 45.0, E = 2.5e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ f+a+++HELRTPL+++r+++elL + t+
FN554766_4 142 NERLFTADVAHELRTPLAGVRLHLELLAK---------TH------- 172

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + + ++++ + +++lL+l+r+++
FN554766_4 173 ----------HIDVAPLVARLDQMMESVSQLLQLARAGQS 202

FN554766_1770: domain 1 of 1, from 211 to 271: score 42.4, E = 1.4e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+k +++ +++HELRTPL +r +e+ + ls+ +
FN554766_1 211 SKKQLIDGIAHELRTPLVRLRYRLEMSDN-----------LSAAE-- 244

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + r++ +l++Li++lL+++r++ +
FN554766_1 245 -------------SQALNRDISQLEALIEELLTYARLDRP 271


Histogram of all scores:
score obs exp (one = represents 16 sequences)
----- --- ---
-15 1 0|=
-14 18 0|==
-13 74 3|*====
-12 231 109|======*========
-11 525 569|================================= *
-10 844 1055|===================================================== *
-9 888 1090|======================================================== *
-8 801 816|==================================================*
-7 566 514|================================*===
-6 356 296|==================*====
-5 216 162|==========*===
-4 98 86|=====*=
-3 64 45|==*=
-2 33 24|=*=
-1 32 12|*=
0 17 6|*=
1 6 3|*
2 8 1|*
3 2 0|=
4 0 0|
> 5 21 -|==


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 311.0246
P(chi-square) = 0

Total sequences searched: 4886

Whole sequence top hits:
tophits_s report:
Total hits: 19
Satisfying E cutoff: 19
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 19
Satisfying E cutoff: 19
Total memory: 28K


Acknowledgements:

This research is funded by:

Developed by: