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Firmicutes Fusobacteria Gammaproteobacteria
Other Bacteria Planctomycetes Spirochaetes
Thermotogae
Classification of phyla is from NCBI page
Search:
264 projects found  

1 accessions found for Escherichia coli str. K-12 substr. MG1655  

Data for U00096  

Available Atlases
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hmmsearch - search a sequence database with a profile HMM
HMMER 2.3.2 (Oct 2003)
Copyright (C) 1992-2003 HHMI/Washington University School of Medicine
Freely distributed under the GNU General Public License (GPL)
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -
HMM file: /home/projects/MicrobialGenomicsGroup/Packages/hmmdata-1.0.0.package/Resources/noarch/TCS/HisKA_1.hmm [HisKA]
Sequence database: U00096.Gprot.fsa
per-sequence score cutoff: >= 26.8 [TC1]
per-domain score cutoff: >= 26.8 [TC2]
per-sequence Eval cutoff: [none]
per-domain Eval cutoff: [none]
- - - - - - - - - - - - - - - - - - - - - - - - - - - - - - - -

Query HMM: HisKA
Accession: PF00512.12
Description: His Kinase A (phosphoacceptor) domain
[HMM has been calibrated; E-values are empirical estimates]

Scores for complete sequences (score includes all domains):
Sequence Description Score E-value N
-------- ----------- ----- ------- ---
U00096_2717 CDS_2913079-2915835 100.1 5.2e-28 1
U00096_0384 CDS_417113-418408 90.3 3.2e-25 1
U00096_2328 CDS_2482396-2485989 81.6 9.1e-23 1
U00096_0963 CDS_1055401-1052657 80.7 1.6e-22 1
U00096_2174 CDS_2317898-2315049 80.6 1.8e-22 1
U00096_3119 CDS_3351047-3348711 78.9 5.5e-22 1
U00096_2175 CDS_2318065-2319891 76.4 2.8e-21 1
U00096_2510 CDS_2689120-2687693 75.4 5.3e-21 1
U00096_2037 CDS_2160900-2162303 69.8 2.1e-19 1
U00096_3795 CDS_4102998-4101625 66.6 1.6e-18 1
U00096_4263 CDS_4634719-4636143 62.4 2.5e-17 1
U00096_3877 CDS_4199949-4201346 61.5 4.6e-17 1
U00096_0554 CDS_593993-592551 61.0 6.4e-17 1
U00096_2943 CDS_3168506-3169855 60.7 8e-17 1
U00096_3753 CDS_4054362-4053313 59.7 1.5e-16 1
U00096_0669 CDS_723637-720953 59.6 1.6e-16 1
U00096_3304 CDS_3533890-3532538 55.0 3.2e-15 1
U00096_1932 CDS_2036176-2034818 52.3 1.8e-14 1
U00096_3984 CDS_4331295-4330204 45.0 2.2e-12 1
U00096_1581 CDS_1680906-1682207 42.4 1.2e-11 1

Parsed for domains:
Sequence Domain seq-f seq-t hmm-f hmm-t score E-value
-------- ------- ----- ----- ----- ----- ----- -------
U00096_2717 1/1 292 357 .. 1 87 [] 100.1 5.2e-28
U00096_0384 1/1 203 269 .. 1 87 [] 90.3 3.2e-25
U00096_2328 1/1 711 777 .. 1 87 [] 81.6 9.1e-23
U00096_0963 1/1 443 508 .. 1 87 [] 80.7 1.6e-22
U00096_2174 1/1 469 534 .. 1 87 [] 80.6 1.8e-22
U00096_3119 1/1 282 347 .. 1 87 [] 78.9 5.5e-22
U00096_2175 1/1 388 453 .. 1 87 [] 76.4 2.8e-21
U00096_2510 1/1 249 317 .. 1 87 [] 75.4 5.3e-21
U00096_2037 1/1 240 304 .. 1 87 [] 69.8 2.1e-19
U00096_3795 1/1 238 300 .. 1 87 [] 66.6 1.6e-18
U00096_4263 1/1 255 320 .. 1 87 [] 62.4 2.5e-17
U00096_3877 1/1 244 310 .. 1 87 [] 61.5 4.6e-17
U00096_0554 1/1 261 327 .. 1 87 [] 61.0 6.4e-17
U00096_2943 1/1 236 302 .. 1 87 [] 60.7 8e-17
U00096_3753 1/1 129 186 .. 1 79 [. 59.7 1.5e-16
U00096_0669 1/1 663 730 .. 1 87 [] 59.6 1.6e-16
U00096_3304 1/1 233 293 .. 1 87 [] 55.0 3.2e-15
U00096_1932 1/1 235 301 .. 1 87 [] 52.3 1.8e-14
U00096_3984 1/1 142 202 .. 1 87 [] 45.0 2.2e-12
U00096_1581 1/1 211 271 .. 1 87 [] 42.4 1.2e-11

Alignments of top-scoring domains:
U00096_2717: domain 1 of 1, from 292 to 357: score 100.1, E = 5.2e-28
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
kseflan+sHELRTPL++++g++ l l+ tel++ q
U00096_271 292 IKSEFLANMSHELRTPLNGVIGFTRLTLK---------TELTPTQ-- 327

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+ l+ti+r+a+ ll++ind+Ld+s++eag
U00096_271 328 ----------RDHLNTIERSANNLLAIINDVLDFSKLEAG 357

U00096_0384: domain 1 of 1, from 203 to 269: score 90.3, E = 3.2e-25
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++ f+an+sHELRTPLt+++gy+e++ e ++l r
U00096_038 203 ARRNFFANVSHELRTPLTVLQGYLEMMNE---------QPLEGAVR- 239

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l+t++++++r++ L+ +lL+ls+iea
U00096_038 240 ----------EKALHTMREQTQRMEGLVKQLLTLSKIEAA 269

U00096_2328: domain 1 of 1, from 711 to 777: score 81.6, E = 9.1e-23
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks+fla++sHE+RTP+++I+g++elL + ls eqr
U00096_232 711 AKSQFLATMSHEIRTPISSIMGFLELLSG---------SGLSKEQR- 747

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
e+++ ++ +++ll Li ++Ld +ie+g
U00096_232 748 ----------VEAISLAYATGQSLLGLIGEILDVDKIESG 777

U00096_0963: domain 1 of 1, from 443 to 508: score 80.7, E = 1.6e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
aks fla++sHE+RTPL +I+g+a+lL + ++ q
U00096_096 443 AKSAFLAAMSHEIRTPLYGILGTAQLLAD---------NPALNAQ-- 478

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
r+ l+ i +++e+ll ++nd+Ld+s ieag
U00096_096 479 ----------RDDLRAITDSGESLLTILNDILDYSAIEAG 508

U00096_2174: domain 1 of 1, from 469 to 534: score 80.6, E = 1.8e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ks fla++sHELRTPL +I+g+++lL++ el+
U00096_217 469 SKSMFLATVSHELRTPLYGIIGNLDLLQT---------KELPKGV-- 504

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ + +++ ll++i+d+Ld+s+ie++
U00096_217 505 ----------DRLVTAMNNSSSLLLKIISDILDFSKIESE 534

U00096_3119: domain 1 of 1, from 282 to 347: score 78.9, E = 5.5e-22
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
k+ f++++sHELRTPL++I g++ +Ll+ tel++eq
U00096_311 282 DKTTFISTISHELRTPLNGIVGLSRILLD---------TELTAEQ-- 317

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++yl+ti+ +a l ++ nd+ d+ ++e
U00096_311 318 ----------EKYLKTIHVSAVTLGNIFNDIIDMDKMERR 347

U00096_2175: domain 1 of 1, from 388 to 453: score 76.4, E = 2.8e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++e++a+++HE R+PLtaIrgy+++L+ ++ ++ +
U00096_217 388 TLGELMAGVAHEVRNPLTAIRGYVQILRQ---------QTSDPIH-- 423

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+eyl+++l+e++++++ i++lL++sr ++
U00096_217 424 ----------QEYLSVVLKEIDSINKVIQQLLEFSRPRHS 453

U00096_2510: domain 1 of 1, from 249 to 317: score 75.4, E = 5.3e-21
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +fl++lsHEL+TPL+++r +elL +++ ++l++eq
U00096_251 249 QRHQFLRHLSHELKTPLASMREGTELLADQV------VGPLTPEQ-- 287

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+e +++++++++ l++Li++lLd+ r +a
U00096_251 288 ----------KEVVSILDSSSRNLQKLIEQLLDYNRKQAD 317

U00096_2037: domain 1 of 1, from 240 to 304: score 69.8, E = 2.1e-19
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++++f+a++sHELRTPL+++rg +e++++++ + ++e+
U00096_203 240 MRRDFMADISHELRTPLAVLRGELEAIQDGV-------RKFTPET-- 277

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ +++ e+ l +L++dl +ls ++g
U00096_203 278 -------------VASLQAEVGTLTKLVDDLHQLSMSDEG 304

U00096_3795: domain 1 of 1, from 238 to 300: score 66.6, E = 1.6e-18
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+++++l+++sHELRTPLt +++ + lL++ +++
U00096_379 238 SQQRLLSDISHELRTPLTRLQLGTALLRR---------RSGESKE-- 273

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
le+i+ ea+rl+++indlL +sr ++
U00096_379 274 -------------LERIETEAQRLDSMINDLLVMSRNQQK 300

U00096_4263: domain 1 of 1, from 255 to 320: score 62.4, E = 2.5e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ + +l HEL+ PL+aIrg+ae+L+e ++ +e
U00096_426 255 YIEQYVYALTHELKSPLAAIRGAAEILRE---------GPPPEVV-- 290

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++++ il + r+++L++ lL +r+e+
U00096_426 291 ----------ARFTDNILTQNARMQALVETLLRQARLENR 320

U00096_3877: domain 1 of 1, from 244 to 310: score 61.5, E = 4.6e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a++ ++a+++HE+R+PL++I+g+a+ e +++++ e
U00096_387 244 ALGHLAAGVAHEIRNPLSSIKGLAKYFAE--------RAPAGGEA-- 280

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++ +++ +ea+rl+r +++lL+l + +
U00096_387 281 ----------HQLAQVMAKEADRLNRVVSELLELVKPTHL 310

U00096_0554: domain 1 of 1, from 261 to 327: score 61.0, E = 6.4e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++s f a+++HE+RTP+t +++ +e++l + +s +++
U00096_055 261 RQSNFSADIAHEIRTPITNLITQTEIALS---------QSRSQKEL- 297

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ l + l+e+ r+ ++++d+L l++++++
U00096_055 298 ----------EDVLYSNLEELTRMAKMVSDMLFLAQADNN 327

U00096_2943: domain 1 of 1, from 236 to 302: score 60.7, E = 8e-17
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ ++f+++++HELR PLta++ +e+++ ++ +++ r
U00096_294 236 RERRFTSDAAHELRSPLTALKVQTEVAQL---------SDDDPQAR- 272

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+++l +++ ++r rL+++lL+lsr+++
U00096_294 273 ----------KKALLQLHSGIDRATRLVDQLLTLSRLDSL 302

U00096_3753: domain 1 of 1, from 129 to 186: score 59.7, E = 1.5e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
a ++++++l+HE+++PL ++rg+a+lL + +l+++ +
U00096_375 129 AARDLVRGLAHEIKNPLGGLRGAAQLLSK----------ALPDPSL- 164

peLRledpeyreyletilreaerllrLindlL<-*
ey+++i+++a+rl++L+++lL
U00096_375 165 ----------LEYTKVIIEQADRLRNLVDRLL 186

U00096_0669: domain 1 of 1, from 663 to 730: score 59.6, E = 1.6e-16
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ +la+lsH+LRTPLt++ g ae+L +l + ++++
U00096_066 663 IRNALLAALSHDLRTPLTVLFGQAEILTLDL-------ASEGSPH-- 700

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
++ + i++ + rL+n+lLd++ri++g
U00096_066 701 ----------ARQASEIRQHVLNTTRLVNNLLDMARIQSG 730

U00096_3304: domain 1 of 1, from 233 to 293: score 55.0, E = 3.2e-15
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++ ++a++sH+LRTPLt Ir+++e++ e ++
U00096_330 233 DRTLLMAGVSHDLRTPLTRIRLATEMMSE---------QD------- 263

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ e+i +++e ++++i+++ d+ r +++
U00096_330 264 ----------GYLAESINKDIEECNAIIEQFIDYLRTGQE 293

U00096_1932: domain 1 of 1, from 235 to 301: score 52.3, E = 1.8e-14
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
++s+f+ +l+HELRTP++a++g ++ l +++s +
U00096_193 235 RLSQFADDLAHELRTPINALLGQNQVTLS---------QTRSIAE-- 270

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
y++ + ++e+e ++rL +++L l+r++ +
U00096_193 271 ---------YQKTIAGNIEELENISRLTENILFLARADKN 301

U00096_3984: domain 1 of 1, from 142 to 202: score 45.0, E = 2.2e-12
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+ f+a+++HELRTPL+++r+++elL + t+
U00096_398 142 NERLFTADVAHELRTPLAGVRLHLELLAK---------TH------- 172

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + + ++++ + +++lL+l+r+++
U00096_398 173 ----------HIDVAPLVARLDQMMESVSQLLQLARAGQS 202

U00096_1581: domain 1 of 1, from 211 to 271: score 42.4, E = 1.2e-11
*->akseflanlsHELRTPLtaIrgyaelLleeldkvlagdtelseeqrl
+k +++ +++HELRTPL +r +e+ + ls+ +
U00096_158 211 SKKQLIDGIAHELRTPLVRLRYRLEMSDN-----------LSAAE-- 244

peLRledpeyreyletilreaerllrLindlLdlsrieag<-*
+ + r++ +l++Li++lL+++r++ +
U00096_158 245 -------------SQALNRDISQLEALIEELLTYARLDRP 271


Histogram of all scores:
score obs exp (one = represents 13 sequences)
----- --- ---
-16 1 0|=
-15 4 0|=
-14 13 0|=
-13 46 3|*===
-12 185 94|=======*=======
-11 419 489|================================= *
-10 706 908|======================================================= *
-9 763 938|==========================================================*
-8 699 702|=====================================================*
-7 504 442|=================================*=====
-6 332 254|===================*======
-5 188 139|==========*====
-4 94 74|=====*==
-3 56 39|==*==
-2 29 20|=*=
-1 35 10|*==
0 16 5|*=
1 6 2|*
2 11 1|*
3 2 0|=
4 0 0|
> 5 22 -|==


% Statistical details of theoretical EVD fit:
mu = -8.9758
lambda = 0.6525
chi-sq statistic = 311.4840
P(chi-square) = 0

Total sequences searched: 4267

Whole sequence top hits:
tophits_s report:
Total hits: 20
Satisfying E cutoff: 20
Total memory: 21K

Domain top hits:
tophits_s report:
Total hits: 20
Satisfying E cutoff: 20
Total memory: 28K


Acknowledgements:

This research is funded by:

Developed by: