| 1 | Nitrosopumilus maritimus SCM1 | ACTM | 19265 | 1 | 1,645,259 | 65.8 | 10 | 10 | 0 | 0 | 0 | 10 |
| 2 | Sulfolobus islandicus M.16.4 | ACTS | 18807 | 1 | 2,586,647 | 65.0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 3 | Sulfolobus islandicus M.16.27 | ACTS | 18873 | 1 | 2,692,402 | 65.0 | 0 | 0 | 0 | 0 | 0 | 0 |
| 4 | Sulfolobus islandicus M.14.25 | ACTS | 18871 | 1 | 2,608,832 | 64.9 | 0 | 0 | 0 | 0 | 0 | 0 |
| 5 | Sulfolobus islandicus L.S.2.15 | ACTS | 18987 | 1 | 2,736,272 | 64.9 | 0 | 0 | 0 | 0 | 0 | 0 |
| 6 | Sulfolobus islandicus L.D.8.5 | ACTS | 18803 | 2 | 2,748,647 | 64.7 | 0 | 0 | 0 | 0 | 0 | 0 |
| 7 | Sulfolobus islandicus Y.N.15.51 | ACTS | 18651 | 2 | 2,854,410 | 64.7 | 0 | 0 | 0 | 0 | 0 | 0 |
| 8 | Sulfolobus islandicus Y.G.57.14 | ACTS | 19487 | 1 | 2,702,058 | 64.6 | 0 | 0 | 0 | 0 | 0 | 0 |
| 9 | Staphylothermus marinus F1 | ACTD | 17449 | 1 | 1,570,485 | 64.3 | 0 | 0 | 0 | 0 | 0 | 0 |
| 10 | Sulfolobus solfataricus P2 | ACTS | 108 | 1 | 2,992,245 | 64.2 | 0 | 0 | 0 | 0 | 0 | 0 |
| 11 | Sulfolobus acidocaldarius DSM 639 | ACTS | 13935 | 1 | 2,225,959 | 63.3 | 0 | 0 | 0 | 0 | 0 | 0 |
| 12 | Staphylothermus hellenicus DSM 12710 | ACTD | 33683 | 1 | 1,580,347 | 63.2 | 0 | 0 | 0 | 0 | 0 | 0 |
| 13 | Caldivirga maquilingensis IC-167 | ACTT | 17421 | 1 | 2,077,567 | 56.9 | 0 | 0 | 0 | 0 | 0 | 0 |
| 14 | Desulfurococcus kamchatkensis 1221n | ACTD | 28141 | 1 | 1,365,223 | 54.7 | 0 | 0 | 0 | 0 | 0 | 0 |
| 15 | Metallosphaera sedula DSM 5348 | ACTS | 17447 | 1 | 2,191,517 | 53.8 | 0 | 0 | 0 | 0 | 0 | 0 |
| 16 | Thermosphaera aggregans DSM 11486 | ACTD | 36571 | 1 | 1,316,595 | 53.3 | 0 | 0 | 0 | 0 | 0 | 0 |
| 17 | Pyrobaculum islandicum DSM 4184 | ACTT | 16743 | 1 | 1,826,402 | 50.4 | 0 | 0 | 0 | 0 | 0 | 0 |
| 18 | Pyrobaculum aerophilum str. IM2 | ACTT | 172 | 1 | 2,222,430 | 48.6 | 0 | 0 | 0 | 0 | 0 | 0 |
| 19 | Hyperthermus butylicus DSM 5456 | ACTD | 208 | 1 | 1,667,163 | 46.3 | 0 | 0 | 0 | 0 | 0 | 0 |
| 20 | Pyrobaculum arsenaticum DSM 13514 | ACTT | 15582 | 1 | 2,121,076 | 44.9 | 0 | 0 | 0 | 0 | 0 | 0 |
| 21 | Aeropyrum pernix K1 | ACTD | 211 | 1 | 1,669,696 | 43.7 | 0 | 0 | 0 | 0 | 0 | 0 |
| 22 | Ignicoccus hospitalis KIN4/I | ACTD | 13914 | 1 | 1,297,538 | 43.5 | 0 | 0 | 0 | 0 | 0 | 0 |
| 23 | Pyrobaculum calidifontis JCM 11548 | ACTT | 18111 | 1 | 2,009,313 | 42.8 | 0 | 0 | 0 | 0 | 0 | 0 |
| 24 | Thermofilum pendens Hrk 5 | ACTT | 16331 | 2 | 1,813,393 | 42.3 | 0 | 0 | 0 | 0 | 0 | 0 |
| 25 | Thermoproteus neutrophilus V24Sta | ACTT | 15645 | 1 | 1,769,823 | 40.1 | 0 | 0 | 0 | 0 | 0 | 0 |
| 26 | Sulfolobus solfataricus 98/2 | | 30989 | 1 | N/A | N/A | N/A | N/A | N/A | N/A | N/A | N/A |