HLArestrictor 1.2 Server
HLArestrictor is a tool for patient-specific predictions of HLA restriction elements and optimal epitopes
within peptides. Given the high-resolution (i.e. 4-digit) HLA typing of the individual,
HLArestrictor predicts all 8-11mer peptide-binders within one or more larger peptides and provides an
overview of the predicted HLA restrictions and minimal epitopes.
The HLArestrictor-1.2 has been update to the more
recent NetMHCpan-2.4 method for peptide MHC binding predictions.
The project is a collaboration between CBS, and IMMI
View the version history of this server.
All the previous versions are available on line, for comparison and
NOTE - if you submit a large job with running time exceeding 10 hours, please use the HLrrestrictor Heavy Queue submission page. There jobs are allowed to run for up to 4 days.
For publication of results, please cite:
HLArestrictor - a tool for patient-specific predictions of HLA restriction elements and optimal epitopes within peptides
Malene Erup Larsen1,
Catherine K. Koofhethile2,
Soren Buus, and
Immunogenetics. 2010 Nov 16. [Epub ahead of print]
1Center for Biological Sequence Analysis,
Technical University of Denmark,
DK-2800 Lyngby, Denmark
2University of Oxford, Peter Medawar Building for Pathogen Research, South Parks Road, OX1 3SY, Oxford, England
3Laboratory of Experimental Immunology, Faculty of Health Sciences, University of Copenhagen, Denmark
4HIV Pathogenesis Programme, Doris Duke Medical Research Institute, University of KwaZulu-Natal, Durban, South Africa
5Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology and Harvard University, Charlestown, MA, 02129, USA