LipoP 1.0 Server
Prediction of lipoproteins and signal peptides
in Gram negative bacteria
The LipoP 1.0 server produces predictions of lipoproteins and discriminates
between lipoprotein signal peptides, other signal peptides and n-terminal
membrane helices in Gram-negative bacteria.
Note: Although LipoP 1.0 has been trained on sequences from Gram-negative
bacteria only, the following paper reports that it has a good
performance on sequences from Gram-positive bacteria also:
Methods for the bioinformatic identification of bacterial lipoproteins
encoded in the genomes of Gram-positive bacteria
O. Rahman, S. P. Cummings, D. J. Harrington and I. C. Sutcliffe
World Journal of Microbiology and Biotechnology
At most 5000 sequences and 500,000 amino acids per submission; each sequence not less than 70 and not more than 5,000 amino acids.
The sequences are kept confidential and will be deleted after
For publication of results, please cite:
Prediction of lipoprotein signal peptides in Gram-negative bacteria.
A. S. Juncker, H. Willenbrock, G. von Heijne, H. Nielsen, S. Brunak
and A. Krogh.
Protein Sci. 12(8):1652-62, 2003
View the abstract.
Would you prefer to run LipoP at your own site? LipoP 1.0 is available
as a stand-alone software package, with the same functionality as the service
For now only a Linux version exists.
There is a
for academic users; other users are requested to contact CBS Software Package
Manager at email@example.com.