MHCcluster 2.0 Server
The MHC genomic region in most species is extremely polymorphic. The
distinct specificity of the majority of the MHC molecules remains
uncharacterized. The MHCcluster is a tool to functionally cluster MHC
class I molecules (MHCI) based on their predicted binding specificity.
The tool provides highly intuitive heat-map and graphical tree-based
visualizations of the functional relationship between MHC class I and class II
For MHC class I, peptide binding predictions are made using
For MHC class II, peptide binding predictions are made using
View the version history of this server.
All the previous versions are available on line, for comparison and
Note, as of July 8, 2014 peptide binding predictions can be made using either
NetMHCpan version 2.8, or NetMHCpan version 2.7 (the earlier default)
For publication of results, please cite:
- MHCcluster, a method for functional clustering of MHC molecules.
Martin Thomsen, Claus Lundegaard, Soren Buus, Michael Rasmussen, Ole Lund and Morten Nielsen
Immunogenetics. 2013 Jun 18. [Epub ahead of print]