Services are gradually being migrated to
In the near future, will be retired. Please try out the new site.

NetCorona 1.0 Server

Prediction of Coronavirus 3CL Proteinase cleavage sites on amino acid sequences

NetCorona predicts coronavirus 3C-like proteinase (or protease) cleavage sites using artificial neural networks on amino acid sequences. Every potential site is scored and a list is compiled in addition to a graphical representation. Refer to publication for more detailed information and performance values.

Instructions Output format Article abstract


Paste a single sequence or several sequences in FASTA format into the field below:

Submit a file in FASTA format directly from your local disk:

Generate graphics   

At most 10 sequences and 50,000 amino acids per submission; each sequence not more than 10,000 amino acids.

The sequences are kept confidential and will be deleted after processing.


For publication of results, please cite:

Coronavirus 3CL-pro proteinase cleavage sites: Possible relevance to SARS virus pathology
L. Kiemer, O. Lund, S. Brunak, and N. Blom
BMC Bioinformatics 2004, 5:72

View the abstract         Download the PDF


SARS protease cleavage, SARS proteinase cleavage, Avian Infectious Bronchitis Virus (AIBV), Murine Hepatitis Virus (MHV), Human Coronavirus 229E (HCoV-229E), Porcine Epidemic Diarrhea Virus (PEDV), Bovine Coronavirus (BCoV), Transmissible Gastroenteritis Virus (TGV), polyprotein cleavage, host protein cleavage, virus pathology.


Scientific problems:        Technical problems: