SignalP-5.0 Server

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The SignalP 5.0 server predicts the presence of signal peptides and the location of their cleavage sites in proteins from Archaea, Gram-positive Bacteria, Gram-negative Bacteria and Eukarya. In Bacteria and Archaea, SignalP 5.0 can discriminate between three types of signal peptides:

  • Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep)
  • Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp)
  • Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep)
SignalP 5.0 is based on a deep convolutional and recurrent neural network architecture including a conditional random field.

Protein sequences should be not less than 10 amino acids. The maximum number of proteins is 5000.

Eukarya
Gram-positive
Gram-negative
Archaea

Long output
Short output (no figures)


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