SigniSite 2.0 Server

Submission	Sample data
Please note that non-amino acid residue characters, will not be included in the evaluation, i.e. anything other than 'ARNDCQEGHILKMFPSTWYV' will be excluded.	Sample data for test of server functionality is available. The sample data will reproduce the results used on 'output format' page. To load the sample data, simply click the 'Load sample data' button below and 'submit':
Paste a multiple alignment in FASTA format into the field below:
Submit a multiple alignment file in FASTA format directly from your local disk:	HIVdb benchmark data set
	Please click here to download. Please cite:
	- Soo-Yon Rhee, Matthew J. Gonzales, Rami Kantor, Bradley J. Betts, Jaideep Ravela, and Robert W. Shafer (2003) Human immunodeficiency virus reverse transcriptase and protease sequence database. Nucleic Acids Research, 31(1), 298-303. - Shafer RW(2006). Rationale and Uses of a Public HIV Drug-Resistance Database. Journal of Infectious Diseases 194 Suppl 1:S51-8

Instructions on the meaning of the parameters below, can be found here

Significance threshold α =
Method for correction for multiple testing	Bonferroni single-step Holm step-down no correction
Choose sorting of numerical values	decreasing increasing
Unique sequence ID for relative numbering
Type of logo	Significant positions Full logo Significant residues
Please click here for instructions
Should gaps be ignored?		By default SigniSite-2.0 consideres gaps as amino acid residue #21

The sequences are kept confidential and will be deleted after analysis.