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TMHMM Server v. 2.0

Prediction of transmembrane helices in proteins



Submission of a local file in FASTA format (HTML 3.0 or higher)

OR by pasting sequence(s) in FASTA format:

Output format:
Extensive, with graphics
Extensive, no graphics
One line per protein

Other options:
Use old model (version 1)

At most 10,000 sequences and 4,000,000 amino acids per submission; each sequence not more than 8,000 amino acids.

The sequences are kept confidential and will be deleted after processing.


Would you prefer to run TMHMM at your own site? TMHMM 2.0 is available as a stand-alone software package, with the same functionality as the service above. Ready-to-ship packages exist for the most common UNIX platforms. There is a download page for academic users; other users are requested to contact CBS Software Package Manager at


Scientific problems:        Technical problems: