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ThermoP-1.0 - Prediction of GH enzyme melting temperature at pH 5.0

ThermoP is a server that predicts the enzyme melting temperature based on features derived from sequence and a structure homology model. It can handle sequences from GH-family 5, 6, 7, 10, 11, 43 and AA9 (formerly GH61).

Instructions Output format Paper abstract


Paste a single amino acid sequence or several sequences in FASTA format into the field below:

Submit a file in FASTA format directly from your local disk:

At most 100 sequences and 200,000 amino acids per submission; each sequence not more than 6,000 amino acids.

The sequences are kept confidential and will be deleted after processing.


For publication of results, please cite:

Protein features as determinants of wild-type glycoside hydrolase thermostability.
Geertz-Hansen HM, Kiemer L, Nielsen M, et al.
Proteins. 2017;00:1-9.


Technical problems:        Scientific problems: