Events News Research CBS CBS Publications Bioinformatics
Staff Contact About Internal CBS CBS Other

TumorTracer 1.1 Server

Go to version 1.0.

TumorTracer was trained to infer the tissue of origin of a tumor, based on somatic mutation and (when available) copy number data.

TumorTracer 1.1 was developed using the COSMIC Whole Genomes database, version 68.

TumorTracer 1.1 differs from version 1.0 only by the user input format; the underlying prediction algorithm is the same.

Currently, TumorTracer covers the following primary sites:
    breast, endometrium, kidney, large intestine, liver, lung, ovary, pancreas, prostate and skin.

When copy number aberration data is available, performance of TumorTracer 1.1 is increased, but only the following primary sites are included:
    breast, endometrium, kidney, large intestine, lung and ovary.

Reference

Marquard AM, Birkbak NJ, Thomas CE, Favero F, Krzystanek M, Lefebvre C, Ferté C, Jamal-Hanjani M, Wilson GA, Shafi S, Swanton C, Andre C, Szallasi Z, Eklund AC.
TumorTracer: a method to identify the tissue of origin from the somatic mutations of a tumor specimen.
BMC Medical Genomics 2015 Oct 1; 8:58.
Link to journal / PubMed

Instructions Output format Article abstract

SUBMISSION

Sample ID (optional): No spaces allowed

MUTATIONS

Submit VCF file: (explain)

Genome coordinates: (explain)
   GRCh37 (default)
   GRCh38

COPY NUMBER ABERRATIONS (optional)

Submit SCNA file: (explain)

Define cutoffs: (explain)
    Cutoff for deletions
    Cutoff for amplifications

I have read and agree to the Terms and Conditions for use of TumorTracer

Restrictions:
At most 20,000 entries in each of the input files.




GETTING HELP

Scientific problems: