100 points Total, 10 points per question.

Lecture # 9 - Chapter 7 - Gene Mutations

1. a. (5 pts.) Draw a picture of a cell, and show what would happen if you had a somatic mutation - how would this affect the organism? Would the effects be localised or global?
 
 
 

1. b. (5 pts.) Draw a picture of a cell, and show what would happen if you had a germinal mutation - how would this affect the organism? Would the effects be localised or global?
 
 
 
 

2.a. (3 points) Give an example of a Morphological Mutation.

2.b. (3 points) Give an example of a Conditional mutation.

2.c. (4 points) Give an example of a Lethal Mutation

- how can this be inherited?
 

Lecture # 10 - Chapter 16 - The Structures of DNA and Chromosomes

3.a. (2 points) In class we talked about the tips & middle parts of chromosomes.

Name the end or "tips" of chromosomes __________________

3.b. (3 pts.) What unique type of DNA structure does this bit of the chromosome form?

3.c. (3 pts.) What does this have to do with cancer??

3.d. Name the middle-bit of chromosomes __________________


                                                                                 Opportunity to Succeed # 2
                                                                                                            3 October, 1997 page 2
 

Lecture # 11 Ch. 8 - Mutations 1 - Changes in Chromosome Structure

4. List 4 types of chromosomal mutations, and draw a simple picture of each.
 
 

5. Please could you explain why many (most?) chromosomal mutations cause mental retardation?
 
 
 
 
 

Lecture # 12 Ch. 9 - Mutations 2 - Changes in Chromosome Number

6. The following two questions have to do with polyploidy in plants….

a. (5 pts.) How common are polyploids in plants? Why?

b. (5 pts.) Why are bananas sterile?
 
 

Lecture # 13 Chapter 10 - Recombination in Bacteria & Their Viruses

7. In class we talked about 4 different methods by which DNA could enter a bacterial cell. List the 4 methods, and give a brief description of each.
 
 

8. Why is the genetic map of Escherichia coli in minutes??
 
 

Lecture # 14 Chapter 11 - On The Structures of DNA

9. Provide the information for the following sequence:

5' GGAAGAGAAAAGGGAGAGAGGGGGAAGAGAAGGAGAGAGAGAGA 3'

a. (2 pts.) What is the sequence of the other strand of DNA?
(to get full credit, the sequence must be written in the correct order)

b. (4 pts.) What type of helix would you expect this sequence to form?

c. (4 pts.) This sequence is often difficult to read using the "dideoxy" method - what
other sequencing approach might work?
 

Lecture # 15 Chapter 17 - Bacterial Genomics

10. Outline how you might go about finding the gene that codes for a disease such as Alzheimer's.
 
 
 
 
 
 
 

Extra credit: Explain how you think telomerase gene therapy might work for treating cancer.

Back Back to the Genetics syllabus

Last modified on: 2 February, 2000 by Dave Ussery