Link to Lecture Notes
 Biology 210
 GENETICS
Wednesday, 18 February, 1998

Chapter6c

The Structure of Eukaryotic Chromosomes

Part 2: DNA Compaction
in chromatin and chromosomes

Learning Objectives:

1. To be able to list the five different levels of compaction in eukaryotic chromosomes (see the drawing on page 232), and to know the relationship between DNA persistence length and the 11 nm fiber.
 

2. To know the significance of specific DNA sequences in terms of chromatin condensation (e.g., Fragile X) and chromosome breakage points (e.g., Z-DNA)..
 

3. To be able to list the 5 major histone proteins found in Eukaryotes, and to know their evolutionary conservation, how they are modified, and how the nucleosome octamer is assembled.



 

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Last modified on: 2 February, 2000 by Dave Ussery