Link to Lecture Notes
Wednesday, 18 February, 1998
1. To be able to list the
five different levels of compaction in eukaryotic chromosomes (see the
drawing on page 232), and to know the relationship between DNA persistence
length and the 11 nm fiber.
2. To know the significance
of specific DNA sequences in terms of chromatin condensation (e.g., Fragile
X) and chromosome breakage points (e.g., Z-DNA)..
3. To be able to list the
5 major histone proteins found in Eukaryotes, and to know their evolutionary
conservation, how they are modified, and how the nucleosome octamer is
Last modified on: 2 February, 2000 by Dave Ussery