Integrative Systems Biology

This site contains supplementary information and data sets from research publications by the integrative systems biology group at CBS.
To access the material, please visit the page devoted to each specific publication by clicking the links or pictures below:

Genetic and environmental risk factors in congenital heart disease functionally converge in protein networks driving heart development
Kasper Lage, Steven C. Greenway, Jill A. Rosenfeld, Hiroko Wakimoto, Joshua M. Gorham, Ayellet V. Segrè, Amy E. Roberts, Leslie B. Smoot, William T. Pu, Alexandre C. Pereira, Sonia M. Mesquita, Niels Tommerup, Søren Brunak, Blake C. Ballif, Lisa G. Shaffer, Patricia K. Donahoe, Mark J. Daly, Jonathan G. Seidman, Christine E. Seidman*, Lars A. Larsen*
* These authors contributed equally
PNAS Early Edition Aug 16,2012

Dissecting spatio-temporal protein networks driving human heart development and related disorders
Kasper Lage, Kjeld Møllgård, Steven Greenway, Hiroko Wakimoto, Joshua M Gorham, Christopher T Workman, Eske Bendsen, Niclas T Hansen, Olga Rigina, Francisco S Roque, Cornelia Wiese, Vincent M Christoffels, Amy E Roberts, Leslie B Smoot, William T Pu, Patricia K Donahoe, Niels Tommerup, Søren Brunak, Christine E Seidman, Jonathan G Seidman and Lars A Larsen
Molecular Systems Biology 6:381 (2010)

A large-scale analysis of tissue-specific pathology and gene expression of human disease genes and complexes
Kasper Lage*, Niclas Tue Hansen*, E. Olof Karlberg, Aron C. Eklund, Francisco S. Roque, Patricia K. Donahoe, Zoltan Szallasi, Thomas Skøt Jensen, Søren Brunak
* These authors contributed equally
PNAS, 52, 20870-20875 (2008)

A human phenome-interactome network of protein complexes in genetic disorders
Kasper Lage*, E. Olof Karlberg*, Zenia M. Størling, Páll Ísólfur Ólason, Anders Gorm Pedersen, Olga Rigina, Anders M Hinsby, Zeynep Tümer, Flemming Pociot, Niels Tommerup, Yves Moreau and Søren Brunak
* These authors contributed equally
Nature Biotechnology, 25, 309 - 316 (2007)


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