EPipe 0.921.ws0Functional differences of protein variants
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Documentation
This is the Web Service implementation of the EPipe server (http://www.cbs.dtu.dk/services/EPipe)
Input is identical to the paste-and-click version. Output is limited only to the
isoform alignments, feature prediction results, and the remapped coordinates of the predicted
features mapped onto the alignment. All graphical generation is left out. The service runs asynchronously,
split into the following three operations:
1.runService
This operation submit sequences, alignment method plus options, and specification of which feature
predictors to include in the run.
INPUT
|+ modules
||- mpsip : Include PSIpred ('yes' or 'no')
||- mimut : Include I-mutant ('yes' or 'no')
||- msig : Include SignalP ('yes' or 'no')
||- mtmh : Include TMHMM ('yes' or 'no')
||- mpfam : Include PFAM ('yes' or 'no')
||- mpdb : Include PDB structures ('yes' or 'no')
||- mpdbid : Include PDB identity match ('yes' or 'no')
||- mnetph : Include NetPhos ('yes' or 'no')
||- mnetog : Include NetOGlyc ('yes' or 'no')
|.- mnetng : Include NetNGlyc ('yes' or 'no')
|+ alignment
||- method : Alignment method ('clustal','t-coffee','hm3align','dialign')
||+ clustal (configuration parameters for alignment method 'clustal'. Used only with method 'clustal')
|||- clgapopen : Gap opening penalty
|||- clgapext : Gap extention penalty
|||- clendgaps : ? penalty
||.- clgapdist : ? penalty
||+ t-coffee (configuration parameters for alignment method 't-coffee'. Used only with method 't-coffee')
| |- tgapopen : Gap opening penalty
| .- tgapext : Gap extention penalty
.+ sequencedata
.+ sequence (array)
|- id : Identifier
|- comment : Optional comment identifier
.- seq : Identifier
OUTPUT
|- jobid : The 32 byte identification string of the job
|- datetime : The last timepoint at which the status of the job has changed
|- status : Possible values are QUEUED, ACTIVE, FINISHED, WAITING, REJECTED,
| UNKNOWN JOBID or QUEUE DOWN
.- expire : Amount of hours since your job will expire
2. pollQueue
INPUT
.- jobid : The 32 byte identification string of the job
OUTPUT
| jobid : The 32 byte identification string of the job
| datetime : The last timepoint at which the status of the job has changed
| status : Possible values are QUEUED, ACTIVE, FINISHED, WAITING, REJECTED,
| UNKNOWN JOBID or QUEUE DOWN
. expire : Amount of hours since your job will expire
3. fetchResult
INTPUT
.- jobid : The 32 byte identification string of the job
OUTPUT
|+ modules (declares details of feature predictor output)
|.+ module (array)
| |- source : Name of the feature predictor (= module)
| .+ names
| .+ name (array)
| |- color : RGB color used for printing the feature (*)
| |- description : Description of the feature
| |- legend : Indicates of the feature is included in the legend of the plot (*)
| .- value : Value of the feauter
.+ entries (container for sequence )
.+ entry
|- seqid : (0 ...) indicating the sequence number in the order submitted
|- seqname : Name/identifier for sequnced used when submitted - seqid used is
| primary identifer
|- aln : The sequence in the aligned form, including gaps
|- seq : The raw unaligned sequence as submitted
|+ colors (container for residue coloring according the clustal's default coloring scheme)
|.- color : (array, one element per position in the alignment)
.+ modules
.+ module
|- source
.+ modules
.+ features
.+ feature
|- begin : Beginning of predicted feature, relative to orginial sequence
|- end : End of predicted feature, relative to orginial sequence
|- value : Predicted value ( see initial declaration in OUTPUT->modules
|- begin_remap : Beginning of predicted feature, relative to aligned sequence
.- end_remap : End of predicted feature, relative to aligned sequence
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